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95P Integrating plasma ctDNA detection and tumor comprehensive genomic and transcriptomic profiling to maximize the clinical implications of precision oncology 整合血浆ctDNA检测和肿瘤综合基因组和转录组分析，以最大限度地提高精确肿瘤学的临床意义
IF 8.3 2区 医学
ESMO Open Pub Date : 2025-08-01 DOI: 10.1016/j.esmoop.2025.105447
N.H. Vo , N.H. Tran , P. Nguyen , V-A.H. Nguyen , L.N. Tu
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引用次数: 0
99P Pre-analytical barriers to successful molecular profiling 99P分析前障碍成功的分子分析
IF 8.3 2区 医学
ESMO Open Pub Date : 2025-08-01 DOI: 10.1016/j.esmoop.2025.105451
C. Carolyn , S.F. Ang , A. Tan , T.J.Y. Tan , D. Tai , S. Tan , Y.Z. Ong , Z.L. Chan , D.P. Lau , J.C. Yeo , G.S. Tan , F.H.X. Yap , T.K.Y. Tay , L. Low , S. Tee , M. Ng , A. Skanderup , D.S.W. Tan
{"title":"99P Pre-analytical barriers to successful molecular profiling","authors":"C. Carolyn , S.F. Ang , A. Tan , T.J.Y. Tan , D. Tai , S. Tan , Y.Z. Ong , Z.L. Chan , D.P. Lau , J.C. Yeo , G.S. Tan , F.H.X. Yap , T.K.Y. Tay , L. Low , S. Tee , M. Ng , A. Skanderup , D.S.W. Tan","doi":"10.1016/j.esmoop.2025.105451","DOIUrl":"10.1016/j.esmoop.2025.105451","url":null,"abstract":"","PeriodicalId":11877,"journal":{"name":"ESMO Open","volume":"10 ","pages":"Article 105451"},"PeriodicalIF":8.3,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144748570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
92O Clinico-genomic characteristics of lung squamous cell carcinoma without smoking history: A nationwide database analysis in Japan 无吸烟史的肺鳞状细胞癌的临床-基因组特征：日本全国数据库分析
IF 8.3 2区 医学
ESMO Open Pub Date : 2025-08-01 DOI: 10.1016/j.esmoop.2025.105444
Y. Uehara , T. Koyama , R. Kitadai , Y. Okuma , K. Gosho , M.O. Okada , J. Sato , Y. Katsuya , T. Kohno , Y. Goto , N. Yamamoto
{"title":"92O Clinico-genomic characteristics of lung squamous cell carcinoma without smoking history: A nationwide database analysis in Japan","authors":"Y. Uehara , T. Koyama , R. Kitadai , Y. Okuma , K. Gosho , M.O. Okada , J. Sato , Y. Katsuya , T. Kohno , Y. Goto , N. Yamamoto","doi":"10.1016/j.esmoop.2025.105444","DOIUrl":"10.1016/j.esmoop.2025.105444","url":null,"abstract":"","PeriodicalId":11877,"journal":{"name":"ESMO Open","volume":"10 ","pages":"Article 105444"},"PeriodicalIF":8.3,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144748697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
83P Efficacy and safety of KRAS G12C inhibitors across solid tumors: A systematic review and meta-analysis KRAS G12C抑制剂在实体肿瘤中的疗效和安全性：一项系统综述和荟萃分析
IF 8.3 2区 医学
ESMO Open Pub Date : 2025-08-01 DOI: 10.1016/j.esmoop.2025.105433
H.T. Hashim
{"title":"83P Efficacy and safety of KRAS G12C inhibitors across solid tumors: A systematic review and meta-analysis","authors":"H.T. Hashim","doi":"10.1016/j.esmoop.2025.105433","DOIUrl":"10.1016/j.esmoop.2025.105433","url":null,"abstract":"","PeriodicalId":11877,"journal":{"name":"ESMO Open","volume":"10 ","pages":"Article 105433"},"PeriodicalIF":8.3,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144748738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
66eP Survival and safety analysis of adebrelimab combined with chemotherapy as first-line treatment for extensive-stage small cell lung cancer in real-world settings 阿布来单抗联合化疗作为一线治疗广泛期小细胞肺癌的生存和安全性分析
IF 8.3 2区 医学
ESMO Open Pub Date : 2025-08-01 DOI: 10.1016/j.esmoop.2025.105415
L. Yu, C. Guan, Y. Jing
{"title":"66eP Survival and safety analysis of adebrelimab combined with chemotherapy as first-line treatment for extensive-stage small cell lung cancer in real-world settings","authors":"L. Yu, C. Guan, Y. Jing","doi":"10.1016/j.esmoop.2025.105415","DOIUrl":"10.1016/j.esmoop.2025.105415","url":null,"abstract":"","PeriodicalId":11877,"journal":{"name":"ESMO Open","volume":"10 ","pages":"Article 105415"},"PeriodicalIF":8.3,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144748841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
53P Exploiting fusion-derived neoantigens for adjuvant therapy in colorectal cancer 利用融合源性新抗原用于结直肠癌的辅助治疗
IF 8.3 2区 医学
ESMO Open Pub Date : 2025-08-01 DOI: 10.1016/j.esmoop.2025.105402
T.B.Q. Nguyen , L.S. Tran , D.T.P. Tran , Q.T.M. Pham , N. Nguyen , T. Nguyen , H. Tran
{"title":"53P Exploiting fusion-derived neoantigens for adjuvant therapy in colorectal cancer","authors":"T.B.Q. Nguyen , L.S. Tran , D.T.P. Tran , Q.T.M. Pham , N. Nguyen , T. Nguyen , H. Tran","doi":"10.1016/j.esmoop.2025.105402","DOIUrl":"10.1016/j.esmoop.2025.105402","url":null,"abstract":"","PeriodicalId":11877,"journal":{"name":"ESMO Open","volume":"10 ","pages":"Article 105402"},"PeriodicalIF":8.3,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144748948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
56P Bioengineered nanovaccine with a TLR7/8 agonist for needle-free intranasal immunotherapy of metastatic cancer 含TLR7/8激动剂的56P生物工程纳米疫苗用于转移性癌症的无针鼻内免疫治疗
IF 8.3 2区 医学
ESMO Open Pub Date : 2025-08-01 DOI: 10.1016/j.esmoop.2025.105405
B. Kim, S.Y. Lim, P. Liu, J.H. Jeong
{"title":"56P Bioengineered nanovaccine with a TLR7/8 agonist for needle-free intranasal immunotherapy of metastatic cancer","authors":"B. Kim, S.Y. Lim, P. Liu, J.H. Jeong","doi":"10.1016/j.esmoop.2025.105405","DOIUrl":"10.1016/j.esmoop.2025.105405","url":null,"abstract":"","PeriodicalId":11877,"journal":{"name":"ESMO Open","volume":"10 ","pages":"Article 105405"},"PeriodicalIF":8.3,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144749021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
97P Molecular profiling of metastatic non-small cell lung carcinoma: Real-word analysis from a tertiary care centre in India 转移性非小细胞肺癌的分子谱分析：来自印度三级保健中心的实时分析
IF 8.3 2区 医学
ESMO Open Pub Date : 2025-08-01 DOI: 10.1016/j.esmoop.2025.105449
S.J. Cherulil , S. Kombath Payini , G. Kormath Veetil , A. Chandrashekharan , N. Ap
{"title":"97P Molecular profiling of metastatic non-small cell lung carcinoma: Real-word analysis from a tertiary care centre in India","authors":"S.J. Cherulil , S. Kombath Payini , G. Kormath Veetil , A. Chandrashekharan , N. Ap","doi":"10.1016/j.esmoop.2025.105449","DOIUrl":"10.1016/j.esmoop.2025.105449","url":null,"abstract":"","PeriodicalId":11877,"journal":{"name":"ESMO Open","volume":"10 ","pages":"Article 105449"},"PeriodicalIF":8.3,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144749034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
9P Total neoadjuvant therapy with trastuzumab in HER2-positive gastric and gastroesophageal junction adenocarcinoma: Interim analysis results 曲妥珠单抗治疗her2阳性胃和胃食管交界处腺癌的新辅助治疗：中期分析结果
IF 8.3 2区 医学
ESMO Open Pub Date : 2025-08-01 DOI: 10.1016/j.esmoop.2025.105354
R.S. Abdulaeva , L.R. Shulumba , E. Obarevich , D. Gavrilova , N. Besova , A. Rays , G.G. Makiev , A. Margusheva , E. Mustafasade , A. Tryakin , S. Nered , M. Abgaryan , H. Sun , M. Nikulin , O. Abou-Khaidar , N. Kozlov , I. Karasjov , E. Kolobanova , I. Stilidi
{"title":"9P Total neoadjuvant therapy with trastuzumab in HER2-positive gastric and gastroesophageal junction adenocarcinoma: Interim analysis results","authors":"R.S. Abdulaeva , L.R. Shulumba , E. Obarevich , D. Gavrilova , N. Besova , A. Rays , G.G. Makiev , A. Margusheva , E. Mustafasade , A. Tryakin , S. Nered , M. Abgaryan , H. Sun , M. Nikulin , O. Abou-Khaidar , N. Kozlov , I. Karasjov , E. Kolobanova , I. Stilidi","doi":"10.1016/j.esmoop.2025.105354","DOIUrl":"10.1016/j.esmoop.2025.105354","url":null,"abstract":"","PeriodicalId":11877,"journal":{"name":"ESMO Open","volume":"10 ","pages":"Article 105354"},"PeriodicalIF":8.3,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144749108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
108P Urinary microRNA expression signatures as non-invasive biomarkers for predicting bladder cancer progression 108P尿微rna表达特征作为预测膀胱癌进展的非侵入性生物标志物
IF 8.3 2区 医学
ESMO Open Pub Date : 2025-08-01 DOI: 10.1016/j.esmoop.2025.105460
M. Ranjan , P. Jain , I. Singh , M. Kumar , V. Sharma , M. Bargotya , P. Agarwal , B. Das
{"title":"108P Urinary microRNA expression signatures as non-invasive biomarkers for predicting bladder cancer progression","authors":"M. Ranjan , P. Jain , I. Singh , M. Kumar , V. Sharma , M. Bargotya , P. Agarwal , B. Das","doi":"10.1016/j.esmoop.2025.105460","DOIUrl":"10.1016/j.esmoop.2025.105460","url":null,"abstract":"","PeriodicalId":11877,"journal":{"name":"ESMO Open","volume":"10 ","pages":"Article 105460"},"PeriodicalIF":8.3,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144749112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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