{"title":"Racing performance of Standardbred horses following surgical treatment of apical proximal sesamoid bone fractures (49 cases)","authors":"J. J. Burns, K. M. MacMillan, E. John, A. Doyle","doi":"10.1111/eve.14119","DOIUrl":"10.1111/eve.14119","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Apical proximal sesamoid bone (PSB) fractures are a common occurrence in Standardbred racehorses due to the high-intensity nature of their work. Several studies have evaluated the racing performance after surgical removal of apical fracture fragments in Thoroughbred horses, however information pertaining to Standardbred racehorses is limited.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>To (i) describe the distribution of apical PSB fractures in a population of Standardbred racehorses; and (ii) measure return to athletic ability in these horses following surgical removal of apical PSB fracture fragments.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Study design</h3>\u0000 \u0000 <p>Retrospective.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Medical records of Standardbred racehorses presenting to the Atlantic Veterinary College (AVC) for surgical treatment of an apical PSB fracture were reviewed. Lifetime racing records were obtained, and the five race starts before injury and the five race starts following surgical treatment were analysed for total earnings and number of top-3 placings for each horse.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Thirty-three horses raced following surgery; 22 of which were racing prior to injury. No significant differences were found in top-3 placings or monetary earnings for the 22 horses which had raced prior to and after surgery. There was no significant difference in limb or sesamoid affected and return to racing. No associations were found between type of surgery performed or degree of suspensory desmitis and whether the horse returned to racing.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Main limitations</h3>\u0000 \u0000 <p>Small sample size.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>88% of horses that were racing prior to injury also raced following surgical treatment of an apical PSB fracture. Surgical removal of apical PSB fractures in Standardbred racehorses does not appear to affect their future athletic ability.</p>\u0000 </section>\u0000 </div>","PeriodicalId":11786,"journal":{"name":"Equine Veterinary Education","volume":"37 8","pages":"444-448"},"PeriodicalIF":0.8,"publicationDate":"2025-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/eve.14119","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144537216","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Atypical myopathy associated with box elder in Europe","authors":"E. J. Knowles, R. J. Piercy","doi":"10.1111/eve.14117","DOIUrl":"10.1111/eve.14117","url":null,"abstract":"<p>The case report by Jahn et al. (<span>2025</span>) describes a case of atypical myopathy in Europe caused by ingestion of the protoxin hypoglycin A (HGA) from box elder seedlings. This is an important report. It reminds clinicians in Europe that trees other than The European sycamore (<i>Acer pseudoplatanus</i>) may contain HGA and that there is a potential for other unfamiliar plant species to cause pasture-associated toxicities.</p><p>After many years of research, the pathogenesis of atypical myopathy, also known as seasonal pasture myopathy, is now well understood. The severe myopathy results from the ingestion of the seeds or seedlings of European sycamore (<i>Acer pseudoplatanus</i>) in Europe and the box elder (<i>Acer negundo</i>) in the USA (Valberg et al., <span>2013</span>; Westermann et al., <span>2008</span>). The seeds, seedlings, and leaves of these trees contain the protoxin HGA, and to a lesser extent its analogue methylenecyclopropylglycine (MCPrG; Bochnia et al., <span>2019</span>). These protoxins are metabolised to the active toxins methylenecyclopropylacetyl-CoA (MCPA-CoA) and MCPrG-CoA, respectively, at tissue-specific rates and primarily in skeletal muscle (Sander et al., <span>2023</span>). The toxic effects mainly occur in the highly-oxidative ‘slow-twitch’ type I muscle fibres such as the postural muscles, masseters, diaphragm and cardiac muscle (Cassart et al., <span>2007</span>). The primary toxin, MCPA-CoA inhibits acyl-CoA dehydrogenase enzymes involved in the beta-oxidation of fatty acids and catabolism of branched-chain amino acids resulting in failure of mitochondrial energy generation and subsequently muscle cell death (Westermann et al., <span>2008</span>). Inhibition of Acyl-CoA dehydrogenase enzymes causes an accumulation of their acyl-CoA substrates and the carnitine and glycine conjugates of those substrates in serum and urine, a characteristic metabolic profile known as multiple acyl-CoA dehydrogenase deficiency (MADD) (Westermann et al., <span>2008</span>). The accumulation of acylcarnitines together with the protoxins (HGA and MCPrG) and the carnitine conjugates of the toxins (MCPA-carnitine and MCPF-carnitine) can be detected in serum by liquid-chromatography-mass-spectometry (LCMS) (Bochnia et al., <span>2019</span>; González-Medina et al., <span>2021</span>; Valberg et al., <span>2013</span>).</p><p>In many cases a diagnosis of atypical myopathy can be made relatively confidently based on the characteristic clinical signs, serum biochemical changes, the seasonal occurrence and, in Europe, the presence of sycamore (<i>Acer psuedoplatanus</i>) seeds or seedlings on the pasture (Dunkel et al., <span>2018</span>; González-Medina et al., <span>2017</span>). Detection of serum HGA or MCPA-carnitine by LCMS may be useful to confirm the diagnosis and may be particularly useful to identify sub-clinically affected cases, or those with less-severe or unusual presentations or when a toxic (tree) source cannot r","PeriodicalId":11786,"journal":{"name":"Equine Veterinary Education","volume":"37 5","pages":"231-233"},"PeriodicalIF":0.8,"publicationDate":"2025-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/eve.14117","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143749972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
T. Gamonal Cembraro, S. Fernández-Carnero, J. N. Cuenca-Zaldívar, L. Jiménez-Ortega, N. Cadeau Comte, E. A. Sánchez Romero
{"title":"How do equine welfare states influence humans and vice versa: Can the welfare of both species be improved if this is considered?","authors":"T. Gamonal Cembraro, S. Fernández-Carnero, J. N. Cuenca-Zaldívar, L. Jiménez-Ortega, N. Cadeau Comte, E. A. Sánchez Romero","doi":"10.1111/eve.14103","DOIUrl":"10.1111/eve.14103","url":null,"abstract":"","PeriodicalId":11786,"journal":{"name":"Equine Veterinary Education","volume":"37 6","pages":"284-287"},"PeriodicalIF":0.8,"publicationDate":"2025-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143914705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Mikic, F. Frers, L. Wittenberg-Voges, M. Hellige
{"title":"Spinal ataxia and computed tomography findings in a Poitou donkey affected with congenital occipitoatlantoaxial malformation","authors":"M. Mikic, F. Frers, L. Wittenberg-Voges, M. Hellige","doi":"10.1111/eve.14108","DOIUrl":"https://doi.org/10.1111/eve.14108","url":null,"abstract":"<p>A 3-year-old Poitou donkey was referred for a computed tomography (CT) examination of the cervical spine due to acute deterioration of spinal ataxia. Neurological assessment revealed restricted neck mobility, hypermetria and circumduction of all limbs, indicating a grade 2 out of 5 ataxia. Abnormalities of the neurologic examination were most likely associated with spinal cord disease between C1 and C5. CT examination identified an asymmetric, congenital, occipitoatlantoaxial malformation (OAAM). A static extradural compression of the spinal cord secondary to the malformation was present. This case report represents an inaugural documentation of OAAM in a Poitou donkey.</p>","PeriodicalId":11786,"journal":{"name":"Equine Veterinary Education","volume":"37 11","pages":"e261-e265"},"PeriodicalIF":0.8,"publicationDate":"2025-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://beva.onlinelibrary.wiley.com/doi/epdf/10.1111/eve.14108","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145237315","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Rivera Maza, R. C. Bishop, S. M. Austin, J. H. Foreman, P. A. Wilkins
{"title":"Characteristics of meconium impaction/retention in newborn foals: From 2006 to 2024","authors":"S. Rivera Maza, R. C. Bishop, S. M. Austin, J. H. Foreman, P. A. Wilkins","doi":"10.1111/eve.14109","DOIUrl":"10.1111/eve.14109","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Meconium impaction/retention is a significant cause of colic in foals. Historically, limitations of both medical and surgical treatment are noted. Outcomes of meconium impaction/retention have not recently been reported.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>To describe case characteristics and outcomes in foals with meconium impaction/retention.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Study design</h3>\u0000 \u0000 <p>Retrospective, single referral hospital.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Medical records from 2006 to 2024 were searched for foals ≤3 days old with a history of straining to defecate, abdominal distention, colic, weakness and/or tail flagging. Signalment, presenting complaint, treatment, outcome and comorbidities were summarised and compared between groups based on sex and survival. Associations between comorbidities and survival were evaluated by zero-inflated Poisson regression.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Forty-three foals met the inclusion criteria. Male foals dominated (30/43; 70%). All foals were managed with enemas; phosphate (11/43; 30%), water with soap/lube (25/43; 58%), not specified 9/43 (21%), multiple types (8; 19%), acetylcysteine retention (1; 2%). Forty foals (93%) survived to discharge, and three (7%) were humanely euthanised. Of surviving foals, 37/40 (93%) responded fully to medical treatment. Surgical treatment was required in 4 foals (9%); 3/4 (75%) survived. Comorbidities were common including sepsis (10/43; 23%), pneumonia (10/43; 23%), failure of passive transfer (6/43; 14%) and hypoxic-ischaemic encephalopathy (5/43; 12%). Non-survivors (3/43; 7%) were euthanised due to sepsis, limb malformation and pneumonia.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Main limitations</h3>\u0000 \u0000 <p>Small sample size and low number of non-survivors prevented meaningful statistical analysis.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Medical management of meconium impaction/retention is successful in the great majority of cases. Prognosis depends on the comorbidities present.</p>\u0000 </section>\u0000 </div>","PeriodicalId":11786,"journal":{"name":"Equine Veterinary Education","volume":"37 11","pages":"587-592"},"PeriodicalIF":0.8,"publicationDate":"2025-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12341383/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144844976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Intra-articular corticosteroids: Systematic review of effects of multiple injections and different doses","authors":"P. K. A. Tokawa, R. Y. A. Baccarin, G. M. Zanotto","doi":"10.1111/eve.14098","DOIUrl":"10.1111/eve.14098","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Corticosteroids are commonly used for intra-articular (IA) treatment of osteoarthritis (OA); however, controversy exists regarding its use as a multiple-injection treatment and for appropriate dosing.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>This systematic review collected and critically appraised evidence regarding the effects of (1) multiple injections protocols for OA treatment in horses and humans; (2) different doses of corticosteroids for treating OA in horses and humans; (3) different doses of corticosteroids in challenged joint tissues/cells in vitro.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Study design</h3>\u0000 \u0000 <p>Systematic review.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Titles published up to June 2022 generated by searches in PubMed, CAB and the Web of Science were screened using general inclusion criteria. Each question (multiple treatments; different doses in vivo and in vitro) had further inclusion requirements. The risk of bias was assessed according to the study design. Horses were the species of interest but human studies were also considered.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Of 6417 titles generated by the systematic search, only nine met all inclusion criteria for question 1, one was included for question 2 and 11 for question 3. Most studies showed unclear/high risk of bias. Multiple-injection protocols showed better symptom-modifying changes at first injections with decreasing improvements over time or for shorter follow-ups in both humans and horses. Disease-modifying changes improved over shorter follow-ups; however, at longer periods, negative effects were seen. Determining the dose effect of different doses of corticosteroids was challenging as only one in vivo study met the inclusion criteria. In vitro, lower doses appeared to be safer for articular tissues.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Main limitations</h3>\u0000 \u0000 <p>Lack of studies meeting inclusion criteria.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>No benefits but drawbacks of multiple IA injections in the long term were found in this review. Results regarding the dose of corticosteroids in OA joints were poorly available in vivo and support the use of lower doses. In vitro, studies pointed out that lower doses might be safer for joint tissues.</p>\u0000 </section>\u0000 </div>","PeriodicalId":11786,"journal":{"name":"Equine Veterinary Education","volume":"37 10","pages":"522-531"},"PeriodicalIF":0.8,"publicationDate":"2025-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://beva.onlinelibrary.wiley.com/doi/epdf/10.1111/eve.14098","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144935423","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
T. C. Rosa, M. T. Magalhães, I. Santos, M. Uva, S. Ramos, L. R. G. Pardon Lamas
{"title":"Outcome and survival of septic arthritis treated with 0.05% chlorhexidine solution: Description of 10 cases","authors":"T. C. Rosa, M. T. Magalhães, I. Santos, M. Uva, S. Ramos, L. R. G. Pardon Lamas","doi":"10.1111/eve.14104","DOIUrl":"10.1111/eve.14104","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Established or ongoing septic arthritis requiring repeated joint flushing remains a treatment challenge with a poor survival outcome aggravated by the necessity of controlled antimicrobial usage.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>To describe the outcomes and survival rates of patients with synovial sepsis treated by lavage with a 0.05% chlorhexidine solution.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Study design</h3>\u0000 \u0000 <p>Clinical retrospective observational study.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Patients with synovial sepsis underwent standing needle or arthroscopic lavage under general anaesthesia with a 0.05% chlorhexidine solution, followed by Lactate Ringer Solution (LRS). Complementary systemic and regional antibiotics were used. Short- (6 months) and long-term (>1 year) outcomes were assessed.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Ten horses met the inclusion criteria. Affected joints included metacarpophalangeal joints (2), tarsocrural joint (1), radiocarpal and intercarpal joints (2), distal interphalangeal joints and navicular bursa (3), distal interphalangeal joints (2). Time from onset to referral ranged from 1 to 20 days, with a mean of 8.3 days. Eighty per cent of horses survived for more than 1 year. Four horses were retired to the field, three returned to a light level of work and one went back to full work.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Main limitations</h3>\u0000 \u0000 <p>Retrospective study of a limited group of horses initially treated by different clinicians before referral, as such, first-line treatment had differences between cases. Resolution was evaluated on based clinical signs rather than clinical pathology of synovial fluid due to clinical decisions or difficulty in obtaining samples.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>With this series of challenging synovial sepsis cases treated by lavage with a chlorhexidine solution, we provide a treatment protocol, proof of clinical concept and report patients' short- and long-term clinical outcomes. Short- and long-term postoperative lameness should be expected despite the resolution of the septic arthritis. This treatment poses a novel option for challenging cases but should be regarded as a salvage procedure due to the possibility of long-term mild lameness.</p>\u0000 </section>\u0000 </div>","PeriodicalId":11786,"journal":{"name":"Equine Veterinary Education","volume":"37 10","pages":"532-538"},"PeriodicalIF":0.8,"publicationDate":"2025-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144935424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. McCullagh, M. C. M. Dosi, J. A. Keen, N. Parkinson, A. Tay, B. C. McGorum
{"title":"Return of a racehorse to racing after iatrogenic lipoid pneumonia","authors":"S. McCullagh, M. C. M. Dosi, J. A. Keen, N. Parkinson, A. Tay, B. C. McGorum","doi":"10.1111/eve.14101","DOIUrl":"10.1111/eve.14101","url":null,"abstract":"<p>There is a paucity of literature describing equine lipoid pneumonia (LP) caused by inadvertent intrapulmonary administration of liquid paraffin (mineral oil). This case report improves our understanding of LP by describing; (1) the first reported return of a horse to racing after LP, (2) the likely benefits of prolonged dexamethasone administration, (3) the detailed short- and long-term pulmonary and systemic responses to intrapulmonary liquid paraffin and (4) the prolonged pulmonary retention of liquid paraffin.</p>","PeriodicalId":11786,"journal":{"name":"Equine Veterinary Education","volume":"37 7","pages":"e105-e111"},"PeriodicalIF":0.8,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/eve.14101","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144207035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E. de Bruijn, L. Rutigliano, R. Hiltrop, K. Chiers, E. Raes, E. Paulussen
{"title":"Uncommon presentation of an invasive T-cell lymphoma in a young Warmblood stallion","authors":"E. de Bruijn, L. Rutigliano, R. Hiltrop, K. Chiers, E. Raes, E. Paulussen","doi":"10.1111/eve.14099","DOIUrl":"10.1111/eve.14099","url":null,"abstract":"<div>\u0000 \u0000 <p>A 2-year-old stallion was referred to the Department of Internal Medicine, Reproduction and Population Medicine of Ghent University with signs of lethargy and anorexia. Abdominal and thoracic ultrasound appeared normal. Biochemistry revealed severe liver dysfunction and haematology indicated a leucocytosis. Therefore, treatment with broad-spectrum antimicrobials and supportive perfusion therapy was initiated. After a few days severe quidding was observed. Oral examination identified a suspected mass of the soft palate. Radiographs confirmed the presence of a soft tissue mass in the left maxillary sinuses. Due to cost constraints, computed tomography (CT) could not be performed. As the clinical condition deteriorated, the stallion was euthanised. Post-mortem examination revealed an unusual, multicentric T-cell lymphoma, characterised by a primary, bilaterally symmetrical, severely invasive mass in the head with metastases in numerous lymph nodes and multiple thoracic and abdominal organs.</p>\u0000 </div>","PeriodicalId":11786,"journal":{"name":"Equine Veterinary Education","volume":"37 8","pages":"e153-e158"},"PeriodicalIF":0.8,"publicationDate":"2025-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144536942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Metabolic encephalopathy associated with uraemic syndrome and hyperammonaemia in a horse presenting with renal failure","authors":"T. Fernandes, M. Robin","doi":"10.1111/eve.14096","DOIUrl":"10.1111/eve.14096","url":null,"abstract":"<div>\u0000 \u0000 <p>A 3-year-old racing Arabian mare was admitted to the hospital with a 5-day history of muscle pain, lethargy and anorexia. The mare arrived at the hospital with marked neurological abnormalities, dehydration and melaena. Investigation revealed severe azotaemia, acute renal failure, hyperammonaemia and evidence of recent myopathy. Therapeutic objectives were the correction of fluid deficiencies and restoration of normal renal function and urine production. The mare responded rapidly to treatment and was discharged after 12 days, before going on to race the following year. To the authors' knowledge, this is the first report of survival of a case of acute renal failure with metabolic encephalopathy associated with hyperammonaemia and uraemic syndrome in the horse. Additionally, the case had symptoms of GI disease consistent with uraemic damage to the intestine.</p>\u0000 </div>","PeriodicalId":11786,"journal":{"name":"Equine Veterinary Education","volume":"37 5","pages":"e85-e91"},"PeriodicalIF":0.8,"publicationDate":"2025-01-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/eve.14096","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143749881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}