{"title":"Progressive sequential development of left and right-sided idiopathic recurrent laryngeal neuropathy in a Standardbred racehorse","authors":"H. M. B. Olsen, R. Sørby, E. Strand","doi":"10.1111/eve.14089","DOIUrl":"https://doi.org/10.1111/eve.14089","url":null,"abstract":"<p>A 4-year-old Standardbred racehorse presented to the hospital due to poor performance and abnormal respiratory noises. A high-speed treadmill videoendoscopic examination including tracheal airway pressure measurements was performed. Grade C left recurrent neuropathy was diagnosed and a prosthetic laryngoplasty was performed. Following surgery, the horse went back into training and eventually racing and performed well in its first two starts. Ten and a half months later the horse re-presented with abnormal respiratory noise, and poor performance had returned. Therefore, the examination was repeated. This revealed that the left arytenoid cartilage was in a similar abducted position as immediately after prosthetic laryngoplasty surgery. However, right-sided arytenoid paresis was present as well as bilateral aryepiglottic fold collapse and right vocal fold collapse. Bilateral aryepiglottic fold resection and right vocal cordectomy was performed using a diode laser under standing sedation. The horse presented a third time, four and a half months later. At this point, the horse had developed right arytenoid paralysis, and it was euthanised. Necroscopy and histopathological examinations were performed. The right cricoarytenoideus dorsalis muscle was moderately reduced in size and showed signs of denervation atrophy. There was loss of normal myelinated fibres of both recurrent laryngeal nerves as well as evidence of active degeneration of the right recurrent laryngeal nerve. In the way the horse sequentially developed first left-sided then right-sided arytenoid paralysis, combined with histological evidence of nerve degeneration, a diagnosis of ‘clinical’ bilateral idiopathic recurrent laryngeal neuropathy was established.</p>","PeriodicalId":11786,"journal":{"name":"Equine Veterinary Education","volume":"37 6","pages":"e98-e104"},"PeriodicalIF":0.8,"publicationDate":"2025-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/eve.14089","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143913989","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Review of intra-articular 2.5% polyacrylamide hydrogel, a new concept in the management of osteoarthritis","authors":"A. Tnibar","doi":"10.1111/eve.14087","DOIUrl":"https://doi.org/10.1111/eve.14087","url":null,"abstract":"<div>\u0000 \u0000 <p>Recent observational and experimental trials have demonstrated that intra-articular 2.5% injectable polyacrylamide hydrogel (2.5 iPAAG) is highly effective, lasting and safe for the treatment of equine osteoarthritis (OA). Over the last decade, intra-articular 2.5 iPAAG has shown to be a potent and promising drug in the medication of OA in horses, as no other single medical treatment for OA has such prolonged efficacy. Preliminary observations on the mechanisms of action of intra-articular 2.5 iPAAG support a mechanical effect through integration into the synovial membrane, an increase in joint elasticity possibly reducing overall joint capsule stiffness, and provision of lasting viscosupplementation which contributes to protecting articular surfaces. Because 2.5 iPAAG is an inert and biocompatible hydrogel, no effects on arthrocentesis cytology parameters have been observed. Studies also suggest that the positive effects of 2.5 iPAAG occur in the absence of intra-articular neurotoxicity or fibrosis, with a low-level macrophage-driven foreign body response. The effect on the synovial membrane and joint capsule and the long-acting viscosupplementation represent new concepts in the management of equine OA.</p>\u0000 </div>","PeriodicalId":11786,"journal":{"name":"Equine Veterinary Education","volume":"37 3","pages":"161-168"},"PeriodicalIF":0.8,"publicationDate":"2024-12-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143253387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Partial arytenoidectomy in 21 standing draught horses with recurrent laryngeal neuropathy","authors":"S. M. Gray, S. D. Gutierrez-Nibeyro","doi":"10.1111/eve.14092","DOIUrl":"https://doi.org/10.1111/eve.14092","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>To report the use of standing partial arytenoidectomy (PA) in draught horses affected by left-sided recurrent laryngeal neuropathy (RLN).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Study design</h3>\u0000 \u0000 <p>Retrospective descriptive study.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Animals</h3>\u0000 \u0000 <p>Twenty-one draught horses diagnosed with left-sided recurrent laryngeal neuropathy (RLN).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Medical records of 21 draught horses subjected to standing PA to treat left-sided RLN were reviewed. Data recorded included history, signalment, presenting complaint, athletic or intended use, pre- and postoperative resting upper respiratory tract endoscopic findings, perioperative medication, surgical details, postoperative exercise recommendations and follow-up.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Twenty-one horses (100%) had a history of abnormal respiratory noise and 15 horses (71%) had exercise intolerance. Of the 19 horses with follow-up, surgery resolved or significantly reduced the abnormal respiratory noise in 17 horses (90%) and resolved exercise intolerance in all 13 horses with a history of exercise intolerance and follow-up. None of the horses had signs or evidence of coughing at the time of follow-up.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Standing left-sided PA can resolve the clinical signs associated with left-sided RLN in draught horses.</p>\u0000 </section>\u0000 </div>","PeriodicalId":11786,"journal":{"name":"Equine Veterinary Education","volume":"37 6","pages":"293-298"},"PeriodicalIF":0.8,"publicationDate":"2024-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/eve.14092","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143914285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Insulin resistance versus dysregulation—a distinction without a difference","authors":"E. M. Kellon","doi":"10.1111/eve.14082","DOIUrl":"https://doi.org/10.1111/eve.14082","url":null,"abstract":"<p>For the last 10 years, the term ‘insulin dysregulation’ has replaced ‘insulin resistance’ when referring to horses with hyperinsulinaemia. The rationale was that this was an all-inclusive term that covered all possible causes of hyperinsulinaemia. The implication is that hyperinsulinaemia has been shown to occur outside of insulin resistance; with insulin resistance being defined as failure of the insulin-sensitive cells to respond normally to insulin, as best documented by the euglycaemic hyperinsulinaemic clamp. This article will show the evidence for that is weak to nonexistent in the horse and the term ‘insulin dysregulation’ is a misnomer that should be abandoned.</p>","PeriodicalId":11786,"journal":{"name":"Equine Veterinary Education","volume":"37 4","pages":"210-215"},"PeriodicalIF":0.8,"publicationDate":"2024-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/eve.14082","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143554370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Identifying the causes of chronic unilateral nasal discharge in the horse","authors":"P. M. Dixon","doi":"10.1111/eve.14077","DOIUrl":"https://doi.org/10.1111/eve.14077","url":null,"abstract":"<div>\u0000 \u0000 <p>This article briefly reviews the causes of unilateral nasal discharge associated with sinonasal disease in the horse. While computed tomographic and radiographic imaging are often of great diagnostic value, clinical and nasal endoscopic examinations are the initial steps in investigating these disorders. This article reviews the use of oral examination and nasal endoscopy in the investigation of nasal discharge caused by sinonasal disease.</p>\u0000 </div>","PeriodicalId":11786,"journal":{"name":"Equine Veterinary Education","volume":"37 3","pages":"117-124"},"PeriodicalIF":0.8,"publicationDate":"2024-11-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143253410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
P. Jahn, T. Novotná, R. Brumarová, D. Dobešová, L. Ottová, D. Friedecký, P. Maršálek
{"title":"Horse with myopathy caused by consumption of box elder tree seedlings in the Czech Republic","authors":"P. Jahn, T. Novotná, R. Brumarová, D. Dobešová, L. Ottová, D. Friedecký, P. Maršálek","doi":"10.1111/eve.14081","DOIUrl":"https://doi.org/10.1111/eve.14081","url":null,"abstract":"<p>An 18-year-old Saxon Warmblood gelding was referred to an equine clinic in the Czech Republic in May 2019 for mild colic. The horse had 7 h of grazing and 30–45 min of exercise every day. At the clinic, physical examination ruled out gastrointestinal disease, while clinical pathology confirmed rhabdomyolysis (creatine kinase 29,088 IU/L; reference range 110–250 IU/L). Because of the suspicion of atypical myopathy (AM), metabolomic analysis of hypoglycin A (HGA), 31 acylcarnitines (ACs) and free carnitine was performed in four dry serum and one blood spot. After laboratory confirmation of AM in the patient studied (HGA: 0.757–0.415 μmol/L, ACs elevation), an incriminated pasture was visited and searched for the source of the toxin. No sycamore (<i>Acer pseudoplatanus</i>) was found in the vicinity of the pasture. However, several box elder (<i>Acer negundo</i>) trees were found, and toxicological analysis revealed HGA in the samaras (7.66–296.00 mg/kg), leaves (2.12–9.39 mg/kg) and seedlings (339.00 mg/kg). Not only sycamore but also the box elder tree can be a potential source of poisoning in horses in Europe, particularly in lowland areas with a warm climate.</p>","PeriodicalId":11786,"journal":{"name":"Equine Veterinary Education","volume":"37 5","pages":"e77-e84"},"PeriodicalIF":0.8,"publicationDate":"2024-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/eve.14081","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143749922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
O. Fletcher, J. Mackinder, R. Agass, C. Bianco, A. Ortiz, J. Dixon
{"title":"Imaging and histopathological findings of a third metacarpal aneurysmal bone cyst and pathological proximal suspensory ligament avulsion fracture","authors":"O. Fletcher, J. Mackinder, R. Agass, C. Bianco, A. Ortiz, J. Dixon","doi":"10.1111/eve.14080","DOIUrl":"https://doi.org/10.1111/eve.14080","url":null,"abstract":"<div>\u0000 \u0000 <p>A 10-year-old Quarter Horse mare presented with acute and severe lameness, persisting despite initial farriery intervention. Upon physical examination, palpation of the proximal thirds of the third and fourth metacarpal bones elicited marked pain. Radiographic evaluation revealed a well-defined radiolucency within the proximal third of the left third metacarpal bone, localised to the enthesis of the proximal suspensory ligament. Ultrasonographic findings demonstrated moderate thickening and increased vascularity of the suspensory ligament at this level. Surgical intervention was considered; however, its feasibility was constrained by the atypical nature and location of the lesion. Subsequent magnetic resonance imaging (MRI) provided a detailed characterisation of the lesion, confirming its expansile nature and the suspected associated avulsion fracture presence. Histopathological examination corroborated the diagnosis of an aneurysmal bone cyst (ABC) with an accompanying bone fracture and bone remodelling. Cases like the one described here define the importance of utilising advanced imaging techniques in combination with conventional modalities, especially when diagnosing and assessing the extent of unusual or complex lesions, to inform prognosis and guide treatment decisions. Due to the lesion's intramedullary location, expansile nature and involvement of critical anatomical structures, surgical interventions were limited which led to a recommendation for humane euthanasia.</p>\u0000 </div>","PeriodicalId":11786,"journal":{"name":"Equine Veterinary Education","volume":"37 5","pages":"265-270"},"PeriodicalIF":0.8,"publicationDate":"2024-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143749921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}