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Epilepsy Currents最新文献

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Could the Lateral Hypothalamus Be a New Target for Therapeutic Intervention to Prevent Seizures? 下丘脑外侧能成为治疗干预预防癫痫发作的新靶点吗？
IF 5.8 2区 医学
Epilepsy Currents Pub Date : 2025-04-30 eCollection Date: 2025-07-01 DOI: 10.1177/15357597251337839
Jeffrey H Goodman
{"title":"Could the Lateral Hypothalamus Be a New Target for Therapeutic Intervention to Prevent Seizures?","authors":"Jeffrey H Goodman","doi":"10.1177/15357597251337839","DOIUrl":"10.1177/15357597251337839","url":null,"abstract":"","PeriodicalId":11742,"journal":{"name":"Epilepsy Currents","volume":" ","pages":"305-307"},"PeriodicalIF":5.8,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12043600/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143992297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Relax, but Don't Forget to Breathe: Ictal Central Apnea and SUDEP. 放松，但不要忘记呼吸：关键中枢呼吸暂停和猝死。
IF 5.8 2区 医学
Epilepsy Currents Pub Date : 2025-04-30 eCollection Date: 2025-07-01 DOI: 10.1177/15357597251335680
Ian C Wenker
{"title":"Relax, but Don't Forget to Breathe: Ictal Central Apnea and SUDEP.","authors":"Ian C Wenker","doi":"10.1177/15357597251335680","DOIUrl":"10.1177/15357597251335680","url":null,"abstract":"","PeriodicalId":11742,"journal":{"name":"Epilepsy Currents","volume":" ","pages":"310-312"},"PeriodicalIF":5.8,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12043610/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143997042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Drop of Insight: Blood-Based Clues to Posttraumatic Epilepsy. 一滴洞察力：创伤后癫痫的血液线索。
IF 5.8 2区 医学
Epilepsy Currents Pub Date : 2025-04-30 eCollection Date: 2025-05-01 DOI: 10.1177/15357597251334089
Deanna Necula, Jeanne T Paz
{"title":"A Drop of Insight: Blood-Based Clues to Posttraumatic Epilepsy.","authors":"Deanna Necula, Jeanne T Paz","doi":"10.1177/15357597251334089","DOIUrl":"10.1177/15357597251334089","url":null,"abstract":"","PeriodicalId":11742,"journal":{"name":"Epilepsy Currents","volume":" ","pages":"203-206"},"PeriodicalIF":5.8,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12043612/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143985047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Inflammation Emerges as a Sensitizer of a Heat-Responsive Cation Channel. 炎症作为热反应性阳离子通道的增敏剂出现。
IF 5.8 2区 医学
Epilepsy Currents Pub Date : 2025-04-30 eCollection Date: 2025-05-01 DOI: 10.1177/15357597251334101
Nicholas H Varvel
{"title":"Inflammation Emerges as a Sensitizer of a Heat-Responsive Cation Channel.","authors":"Nicholas H Varvel","doi":"10.1177/15357597251334101","DOIUrl":"10.1177/15357597251334101","url":null,"abstract":"","PeriodicalId":11742,"journal":{"name":"Epilepsy Currents","volume":" ","pages":"184-186"},"PeriodicalIF":5.8,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12043651/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143958217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
From All to One: Can a Large Cohort of Individuals with SCN1A-Related Epilepsy Offer Predictions for Other Individuals With SCN1A Variants? 从所有到一个：SCN1A相关癫痫患者的大队列能否为其他SCN1A变异患者提供预测？
IF 5.8 2区 医学
Epilepsy Currents Pub Date : 2025-04-30 eCollection Date: 2025-05-01 DOI: 10.1177/15357597251333279
Elizabeth E Gerard
{"title":"From All to One: Can a Large Cohort of Individuals with SCN1A-Related Epilepsy Offer Predictions for Other Individuals With SCN1A Variants?","authors":"Elizabeth E Gerard","doi":"10.1177/15357597251333279","DOIUrl":"10.1177/15357597251333279","url":null,"abstract":"","PeriodicalId":11742,"journal":{"name":"Epilepsy Currents","volume":" ","pages":"158-160"},"PeriodicalIF":5.8,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12043658/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143974136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Fyn-ding Novel Therapeutic Targets for Temporal Lobe Epilepsy-Unlikely Partners at the Hippocampal Synapse. 海马突触颞叶癫痫不可能伙伴的新治疗靶点。
IF 5.8 2区 医学
Epilepsy Currents Pub Date : 2025-04-30 eCollection Date: 2025-07-01 DOI: 10.1177/15357597251335683
Larissa Robinson-Cooper, Melissa Barker-Haliski
{"title":"Fyn-ding Novel Therapeutic Targets for Temporal Lobe Epilepsy-Unlikely Partners at the Hippocampal Synapse.","authors":"Larissa Robinson-Cooper, Melissa Barker-Haliski","doi":"10.1177/15357597251335683","DOIUrl":"10.1177/15357597251335683","url":null,"abstract":"","PeriodicalId":11742,"journal":{"name":"Epilepsy Currents","volume":" ","pages":"299-301"},"PeriodicalIF":5.8,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12043599/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143983807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Stigmatizing Impact of Perceived Epilepsy Stigma. 感知癫痫病耻感的污名化影响。
IF 5.8 2区 医学
Epilepsy Currents Pub Date : 2025-04-16 eCollection Date: 2025-07-01 DOI: 10.1177/15357597251325682
Danielle A Becker
{"title":"The Stigmatizing Impact of Perceived Epilepsy Stigma.","authors":"Danielle A Becker","doi":"10.1177/15357597251325682","DOIUrl":"10.1177/15357597251325682","url":null,"abstract":"","PeriodicalId":11742,"journal":{"name":"Epilepsy Currents","volume":" ","pages":"263-265"},"PeriodicalIF":5.8,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12003312/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143990643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Back to the Future: Endophenotypes of Idiopathic Generalized Epilepsy. 回到未来：特发性全身性癫痫的内表型。
IF 5.8 2区 医学
Epilepsy Currents Pub Date : 2025-04-16 DOI: 10.1177/15357597251323127
Peter Widdess-Walsh
{"title":"Back to the Future: Endophenotypes of Idiopathic Generalized Epilepsy.","authors":"Peter Widdess-Walsh","doi":"10.1177/15357597251323127","DOIUrl":"https://doi.org/10.1177/15357597251323127","url":null,"abstract":"","PeriodicalId":11742,"journal":{"name":"Epilepsy Currents","volume":" ","pages":"15357597251323127"},"PeriodicalIF":5.8,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12003322/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143959463","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Epilepsy and Amyloid: The Plot Thickens… So Will the Brain Thin? 癫痫和淀粉样蛋白：情节变厚……那么大脑会变薄吗？
IF 5.8 2区 医学
Epilepsy Currents Pub Date : 2025-04-16 eCollection Date: 2025-07-01 DOI: 10.1177/15357597251333160
Rani A Sarkis
{"title":"Epilepsy and Amyloid: The Plot Thickens… So Will the Brain Thin?","authors":"Rani A Sarkis","doi":"10.1177/15357597251333160","DOIUrl":"10.1177/15357597251333160","url":null,"abstract":"","PeriodicalId":11742,"journal":{"name":"Epilepsy Currents","volume":" ","pages":"266-268"},"PeriodicalIF":5.8,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12003314/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144002759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Do Seizures Damage the Brain?-Cumulative Effects of Seizures and Epilepsy: A 2025 Perspective. 癫痫会损害大脑吗？-癫痫发作和癫痫的累积效应：2025年的展望。
IF 5.8 2区 医学
Epilepsy Currents Pub Date : 2025-04-16 DOI: 10.1177/15357597251331927
Pavel Klein, Enrique Carrazana, Tracy Glauser, Bruce P Herman, Patricia Penovich, Adrian L Rabinowicz, Thomas P Sutula
{"title":"<i>Do Seizures Damage the Brain</i>?-Cumulative Effects of Seizures and Epilepsy: A 2025 Perspective.","authors":"Pavel Klein, Enrique Carrazana, Tracy Glauser, Bruce P Herman, Patricia Penovich, Adrian L Rabinowicz, Thomas P Sutula","doi":"10.1177/15357597251331927","DOIUrl":"https://doi.org/10.1177/15357597251331927","url":null,"abstract":"<p><p>In 1885, William Gowers proposed that epilepsy is a progressive disease, based on clinical evidence before any effective treatments were available. His long-standing hypothesis has been summarized with the statement \"seizures beget seizures.\" Whether this is the case and related questions about seizure-induced modification and damage of brain circuits are of fundamental importance for neurobiological understanding of epilepsy, development of effective treatment strategies, clinical management, and prognostication. Consensus about progression and seizure-induced damage has remained controversial. Here, we critically review these long-standing questions, incorporating perspectives about perceived inconsistencies in past studies, potential implications of recent longitudinal imaging and cognitive studies, and emphasize experimental and clinical gaps that have proved challenging. Answers to these questions are important for development of management strategies to achieve prompt effective acute control of seizures and prevention of their potential recurrence and long-term comorbidities.</p>","PeriodicalId":11742,"journal":{"name":"Epilepsy Currents","volume":" ","pages":"15357597251331927"},"PeriodicalIF":5.8,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12003328/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143958918","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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