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Proceedings of 1994 20th Annual Northeast Bioengineering Conference最新文献

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Mechanism for muscle force deactivation during quick length changes 快速长度变化过程中肌肉力量失活的机制
Proceedings of 1994 20th Annual Northeast Bioengineering Conference Pub Date : 1994-03-17 DOI: 10.1109/NEBC.1994.305163
J. Palladino, A. Noordergraaf
{"title":"Mechanism for muscle force deactivation during quick length changes","authors":"J. Palladino, A. Noordergraaf","doi":"10.1109/NEBC.1994.305163","DOIUrl":"https://doi.org/10.1109/NEBC.1994.305163","url":null,"abstract":"Muscle exhibits complex viscoelastic properties. Neither lumped muscle models nor ultrastructural crossbridge models have been successful in satisfactorily describing these properties, or in proposing a mechanism for their origin. A recently developed large-scale distributed model of a single muscle fiber based on myofilament kinetics is shown capable of describing all four stages of force deactivation following a quick change in muscle length during isometric contraction. In essence, this model implicates muscle's viscoelastic bonds and distributed mechanical properties as the origin of its complex dynamic behavior.<<ETX>>","PeriodicalId":117140,"journal":{"name":"Proceedings of 1994 20th Annual Northeast Bioengineering Conference","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1994-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129657525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Data acquisition in the viral serology laboratory for clinical decision support in AIDS research 病毒血清学实验室数据采集对艾滋病研究的临床决策支持
Proceedings of 1994 20th Annual Northeast Bioengineering Conference Pub Date : 1994-03-17 DOI: 10.1109/NEBC.1994.305158
T.J. Chahil, G. Rao, D. Kristol, R. Stephens, J. Swerdlow, A. Scolpino, T. Denny
{"title":"Data acquisition in the viral serology laboratory for clinical decision support in AIDS research","authors":"T.J. Chahil, G. Rao, D. Kristol, R. Stephens, J. Swerdlow, A. Scolpino, T. Denny","doi":"10.1109/NEBC.1994.305158","DOIUrl":"https://doi.org/10.1109/NEBC.1994.305158","url":null,"abstract":"Research on human immunodeficiency virus (HIV) infection and opportunistic infections (OIs) that accompany acquired immunodeficiency syndrome (AIDS) requires various resources, including biomedical instrumentation, data acquisition programs using high- or low-level languages and database technology. The viral serology laboratory uses various testing methodologies to study the interrelationships of HIV with cytomegalovirus (CMV) and the protein /spl betasub 2/-microglobulin (/spl betasub 2/-M) for various research and clinical protocols. Among other instrumentation, this laboratory uses Abbott's IMx system to detect the concentration or presence of analytes in patient specimens. The IMx system software and hardware provide facilities for data acquisition. This study focuses on the automation of data capture and storage mechanisms following specimen testing involving CMV and /spl betasub 2/-M immunoassays using Abbott's IMx system.<<ETX>>","PeriodicalId":117140,"journal":{"name":"Proceedings of 1994 20th Annual Northeast Bioengineering Conference","volume":"32 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1994-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126745620","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Sources of error in measuring tissue pH with microsensors 用微传感器测量组织pH值的误差来源
Proceedings of 1994 20th Annual Northeast Bioengineering Conference Pub Date : 1994-03-17 DOI: 10.1109/NEBC.1994.305160
A. H. Auerbach, B. Soller, R. Peura
{"title":"Sources of error in measuring tissue pH with microsensors","authors":"A. H. Auerbach, B. Soller, R. Peura","doi":"10.1109/NEBC.1994.305160","DOIUrl":"https://doi.org/10.1109/NEBC.1994.305160","url":null,"abstract":"The use of pH microsensors in tissue is complicated by a rise in pH over a given period of time. One explanation for this occurrence is that the formation of a layer of protein on the surface of a glass electrode may affect the recorded pH. Experiments were designed to study the effect of both a uniform and nonuniform coating of fibrinogen on pH. A uniform coating is seen to affect the recorded value to a greater degree than a nonuniform coating. If a sensor does acquire a uniform layer of protein upon placement in tissue, then this error needs to be further addressed to obtain accurate pH measurements.<<ETX>>","PeriodicalId":117140,"journal":{"name":"Proceedings of 1994 20th Annual Northeast Bioengineering Conference","volume":"32 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1994-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115319293","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 4
A mathematical model of blood flow through stenotic arteries 血液流经狭窄动脉的数学模型
Proceedings of 1994 20th Annual Northeast Bioengineering Conference Pub Date : 1994-03-17 DOI: 10.1109/NEBC.1994.305189
M. Chugani, M. Savic, Z. Macek
{"title":"A mathematical model of blood flow through stenotic arteries","authors":"M. Chugani, M. Savic, Z. Macek","doi":"10.1109/NEBC.1994.305189","DOIUrl":"https://doi.org/10.1109/NEBC.1994.305189","url":null,"abstract":"The authors derive the equation for the velocity vector in the axial direction for an incompressible, Newtonian fluid, flowing through a nonuniform, symmetric, rigid, cylindrical tube. The authors apply their solution to regions of arteriosclerotic plaque in mammalian arteries and state the conditions under which their assumptions are valid. The results of simulations carried out for several shapes and sizes of plaque deposits, which have been modeled by a /spl beta/-distribution, are presented.<<ETX>>","PeriodicalId":117140,"journal":{"name":"Proceedings of 1994 20th Annual Northeast Bioengineering Conference","volume":"65 5","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1994-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132532232","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A hydrophilic self-anchoring material for orthopedic devices 一种用于矫形装置的亲水性自锚材料
Proceedings of 1994 20th Annual Northeast Bioengineering Conference Pub Date : 1994-03-17 DOI: 10.1109/NEBC.1994.305186
A. Sharda, I. Kamel
{"title":"A hydrophilic self-anchoring material for orthopedic devices","authors":"A. Sharda, I. Kamel","doi":"10.1109/NEBC.1994.305186","DOIUrl":"https://doi.org/10.1109/NEBC.1994.305186","url":null,"abstract":"A hydrophilic polymer matrix reinforced with a 3D braided graphite structure is presented as a novel alternative to traditional metallic materials for orthopedic devices. This material has the mechanical properties of bone in the dry state. When fitted into a mold and immersed in an aqueous medium, its swelling tendency causes the application of a radial force on the mold, anchoring the material in place and enhancing bone deposition. The swelling behavior of the poly(acrylic acid) matrix as a function of the concentration of AMA and glycerol was characterized and reduced to 38 vol.%. A push-out test was conducted to determine the strength of the implant/mold interface. This was measured to be 8.3 MPa using an aluminum mold.<<ETX>>","PeriodicalId":117140,"journal":{"name":"Proceedings of 1994 20th Annual Northeast Bioengineering Conference","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1994-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134265669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pulse compression ultrasound for minimization of transmitted peak power 脉冲压缩超声传输峰值功率的最小化
Proceedings of 1994 20th Annual Northeast Bioengineering Conference Pub Date : 1994-03-17 DOI: 10.1109/NEBC.1994.305166
L. Welch
{"title":"Pulse compression ultrasound for minimization of transmitted peak power","authors":"L. Welch","doi":"10.1109/NEBC.1994.305166","DOIUrl":"https://doi.org/10.1109/NEBC.1994.305166","url":null,"abstract":"Spread spectrum pulse compression can be used as a method for reducing peak power so that it is within the bounds of safety guidelines set by the American Institute of Ultrasonic Measurements (AIUM). Pulse compression accomplishes this by implementing a longer length transmitted pulse of lower amplitude while maintaining the same signal gain, resolution, and signal-to-noise ratios. Here, correlation algorithms for implementing such a subsystem are described, as well as computer simulation results for methods that reduce correlation sidelobe levels resulting from that process.<<ETX>>","PeriodicalId":117140,"journal":{"name":"Proceedings of 1994 20th Annual Northeast Bioengineering Conference","volume":"90 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1994-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124633574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Multiresolution analysis of PTCA isopotential maps PTCA等电位图的多分辨率分析
Proceedings of 1994 20th Annual Northeast Bioengineering Conference Pub Date : 1994-03-17 DOI: 10.1109/NEBC.1994.305192
H. On, D. Brooks, R. Macleod, H. Krim
{"title":"Multiresolution analysis of PTCA isopotential maps","authors":"H. On, D. Brooks, R. Macleod, H. Krim","doi":"10.1109/NEBC.1994.305192","DOIUrl":"https://doi.org/10.1109/NEBC.1994.305192","url":null,"abstract":"The discrete wavelet transform is applied as a joint time/space analysis tool for body surface potential maps. The results of the joint time/space analysis are compared with previous work done by using integral maps. The wavelet transform revealed the close relation between temporal and spatial aspects of cardiac signals. The results of the authors' work suggest that the multiresolution signal decomposition via wavelet transforms provides a new and useful approach to evaluate body surface potential maps.<<ETX>>","PeriodicalId":117140,"journal":{"name":"Proceedings of 1994 20th Annual Northeast Bioengineering Conference","volume":"24 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1994-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133555168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Diffusion coefficients mapped MR imaging-with application to human brain diseases 磁共振成像扩散系数图-应用于人类脑部疾病
Proceedings of 1994 20th Annual Northeast Bioengineering Conference Pub Date : 1994-03-17 DOI: 10.1109/NEBC.1994.305168
B. Yu
{"title":"Diffusion coefficients mapped MR imaging-with application to human brain diseases","authors":"B. Yu","doi":"10.1109/NEBC.1994.305168","DOIUrl":"https://doi.org/10.1109/NEBC.1994.305168","url":null,"abstract":"The author investigated the feasibility of detecting human brain lesions by using the magnetic resonance (MR) imaging mapping technique of diffusion coefficients. MR images of a typical normal human brain are shown; a conventional SE image and a diffusion weighted image. It is demonstrated that the ventricles have the highest intensity due to the water consistency of cerebospinal fluid. White matter has the lowest diffusion coefficient because of its lipid consistency. A T1-weighted image of a patient with an aged brain and the diffusion mapped image of the same patient are shown. The size of the ventricles are shown to be larger than normal. A darker area around the ventricle indicates that there could be more fibrous tissue with limited diffusion coefficient due to aging.<<ETX>>","PeriodicalId":117140,"journal":{"name":"Proceedings of 1994 20th Annual Northeast Bioengineering Conference","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1994-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130382466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The approach and evaluation of a university-based rehabilitation engineering project 校本康复工程项目的方法与评价
Proceedings of 1994 20th Annual Northeast Bioengineering Conference Pub Date : 1994-03-17 DOI: 10.1109/NEBC.1994.305187
L. Sarma, J. Lacourse, N. Vroman, R. Croce
{"title":"The approach and evaluation of a university-based rehabilitation engineering project","authors":"L. Sarma, J. Lacourse, N. Vroman, R. Croce","doi":"10.1109/NEBC.1994.305187","DOIUrl":"https://doi.org/10.1109/NEBC.1994.305187","url":null,"abstract":"A university based vocational rehabilitation (VR) team has been formed at the University of New Hampshire (UNH). This team helps the state vocational rehabilitation division in aiding their respective disabled clients with adaptive technical equipment to help make them more productive in their jobs. Here, the UNH/VR team's methodology is described, along with their overall evaluation.<<ETX>>","PeriodicalId":117140,"journal":{"name":"Proceedings of 1994 20th Annual Northeast Bioengineering Conference","volume":"20 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1994-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116904882","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A comparison of diffusive light reflectance from in vitro and in vivo media 体外和体内介质的漫射光反射率比较
Proceedings of 1994 20th Annual Northeast Bioengineering Conference Pub Date : 1994-03-17 DOI: 10.1109/NEBC.1994.305152
M. R. Muller, L. Ostrander
{"title":"A comparison of diffusive light reflectance from in vitro and in vivo media","authors":"M. R. Muller, L. Ostrander","doi":"10.1109/NEBC.1994.305152","DOIUrl":"https://doi.org/10.1109/NEBC.1994.305152","url":null,"abstract":"The shape of surface reflectance curves is compared for a test medium and for the surface of the human limb. A modulated light spot was incident on the surface of the media and mean reflectance was measured at light source-detector separations ranging from 2.5 mm to 34.5 mm. The in vitro model was constructed to approximate a diffusive layered biological medium. The diffusive properties of the model were changed at depth. Both the in vitro and in vivo results are compared with those predicted by diffusion theory for a uniform diffusive medium. The results indicate that the in vitro medium appears to capture the optical behavior of an in vivo medium for surface measurements out to five diffusion lengths. In addition, the data from both media are matched to the uniform diffusive medium predicted by diffusion theory with good agreement at large source-detector separations.<<ETX>>","PeriodicalId":117140,"journal":{"name":"Proceedings of 1994 20th Annual Northeast Bioengineering Conference","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1994-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117235941","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
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