{"title":"A system for cryomicroscopy with thermal and chemical control capabilities","authors":"A. Berube, D. Walcerz","doi":"10.1109/NEBC.1994.305159","DOIUrl":"https://doi.org/10.1109/NEBC.1994.305159","url":null,"abstract":"A cryomicroscopy system is described in which the chemical environment and temperature of a specimen can be independently and simultaneously controlled during a cryopreservation protocol. In this system, temperature is regulated via computer interface, and the actual freezing of a specimen can be precisely controlled by operator input. In addition, the specimen can be continuously viewed during a cryopreservation protocol.<<ETX>>","PeriodicalId":117140,"journal":{"name":"Proceedings of 1994 20th Annual Northeast Bioengineering Conference","volume":"511 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1994-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123069648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Time frequency analysis of the electromyogram during fatigue","authors":"M. Davies, S. Reisman","doi":"10.1109/NEBC.1994.305165","DOIUrl":"https://doi.org/10.1109/NEBC.1994.305165","url":null,"abstract":"Spectral parameters obtained from the surface electromyogram (EMG) signal have been used as indicators of fatigue during a sustained contraction. A new technique, time frequency analysis, was applied to the EMG signal. This technique generates a continuous representation of the changing spectrum of the signal through time. Three types of time frequency distributions were applied to the EMG signal. As predicted, differences existed between the distributions. The amplitude differential from the first time slice of the distribution to the last was the smallest for the short time Fourier transform. The Wigner-Ville distribution was spread out across the most frequencies. Walls appeared in the Choi-Williams distribution, but otherwise it was the most compressed. All the distributions displayed the expected spectral compression; however, more work is necessary to clarify the results.<<ETX>>","PeriodicalId":117140,"journal":{"name":"Proceedings of 1994 20th Annual Northeast Bioengineering Conference","volume":"306 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1994-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123092174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comparative sensitivity analysis between spherical and cylindrical intraventricular impedance imaging catheters","authors":"G. W. Walker, S. Kun, R. Peura","doi":"10.1109/NEBC.1994.305155","DOIUrl":"https://doi.org/10.1109/NEBC.1994.305155","url":null,"abstract":"An intraventricular impedance imaging (III) system, that will be used for assessing electrical and mechanical cardiac properties via an intraventricular catheter, is presently under development. There have been no published results that show which of the available geometries, spherical or cylindrical, is more suitable for an intraventricular catheter. The purpose of this work is to perform a sensitivity analysis on both intraventricular catheters. Numerical simulations were performed using models developed for catheters placed in ellipsoidal heart ventricles. The results indicate that a cylindrical catheter exhibits a greater sensitivity to positional movements and more specificity in calculating the potential distribution on its surface for a given position, when compared with a spherical catheter.<<ETX>>","PeriodicalId":117140,"journal":{"name":"Proceedings of 1994 20th Annual Northeast Bioengineering Conference","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1994-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129930851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Contour extraction from HVEM image of microvessel using active contour models","authors":"M. Xiao, Y.Q. Shi, D. Kristol, L. Horn, P. Englet","doi":"10.1109/NEBC.1994.305193","DOIUrl":"https://doi.org/10.1109/NEBC.1994.305193","url":null,"abstract":"Reports research results on contour extraction from high voltage electron microscope (HVEM) images of thick cross section montages of small blood vessels. The previous work on this subject which was based on the conventional edge detection operations combined with edge linking, has proven inadequate to describe the inner structural compartments of microvessels. Here an active contour model (commonly referred to as \"Snakes\") has been applied to advance the previous work. Active contour models have proven themselves to be a powerful and flexible paradigm for many problems in image understanding, especially in contour extraction from medical images. With the developed energy functions, the active contour is attracted towards the edges under the action of internal forces (describing some elasticity properties of the contour), image forces and external forces by means of minimization of the energy functions. Based on this active model, an effective algorithm is implemented as a powerful tool for 2D contour extraction in the authors' problem for the first time. The results thus obtained turn out to be encouraging.<<ETX>>","PeriodicalId":117140,"journal":{"name":"Proceedings of 1994 20th Annual Northeast Bioengineering Conference","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1994-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125410342","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Classification of multifunction surface EMG using advanced AR model representations","authors":"R. Knox, D.H. Brooks","doi":"10.1109/NEBC.1994.305164","DOIUrl":"https://doi.org/10.1109/NEBC.1994.305164","url":null,"abstract":"The potential use of new features derived from autoregressive coefficients for upper limb EMG pattern recognition has been discussed (Knox et al., 15/sup th/ Ann. Int. Conf. of the IEEE EMBS, San Diego, CA, USA, Oct. 1993). These new features (reflection coefficients, cepstral coefficients, and logarithmic area ratios) are used heavily in speech processing. Results from a nonparametric linear classifier are presented.<<ETX>>","PeriodicalId":117140,"journal":{"name":"Proceedings of 1994 20th Annual Northeast Bioengineering Conference","volume":"290 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1994-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116866503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cyclic variation of the power of ultrasonic Doppler signal from pulsatile blood flow","authors":"S. J. Wu, K. Shung","doi":"10.1109/NEBC.1994.305181","DOIUrl":"https://doi.org/10.1109/NEBC.1994.305181","url":null,"abstract":"Doppler ultrasound has been used as a clinical tool for measuring the velocity of blood flow in vessels for many years. The power of the ultrasonic Doppler signal from blood is related to blood properties and flow conditions i.e., hematocrit, nature of flow, degree of cell aggregation, etc. and has recently been used to obtain the so-called \"power mode\" Doppler images. It would help one to interpret the image if one understood how it changes in response to different conditions. The variation of the power of the ultrasonic Doppler signal from porcine blood during the flow cycle under pulsatile flow conditions has been evaluated experimentally with a 10 MHz pulsed Doppler flowmeter using a pulsatile flow mock loop consisting of a polystyrene or latex vessel model at a peak flow rate of 0.6188 l/min (30 to 60 beats/min), similar to physiological conditions, but of different stroke rates. A significant difference in the cyclic variation of Doppler power is observed as the stroke rate or measuring site is varied.<<ETX>>","PeriodicalId":117140,"journal":{"name":"Proceedings of 1994 20th Annual Northeast Bioengineering Conference","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1994-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125379442","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Baroreceptor reflex sensitivity among stroke survivors: a pilot study","authors":"S. Fernando, S. Reisman, M. Daum, R. Zorowitz","doi":"10.1109/NEBC.1994.305183","DOIUrl":"https://doi.org/10.1109/NEBC.1994.305183","url":null,"abstract":"Baroreceptor reflex sensitivity index (BRSI) derived from phase IV of the Valsalva manoeuvre is used to evaluate heart functioning in stroke survivors. Ten subjects (five normal controls and five stroke survivors) are analyzed and compared. The comparison shows that stroke patients have a lower BRSI value than normal subjects and the values fall into the range characterized as clinically depressed.<<ETX>>","PeriodicalId":117140,"journal":{"name":"Proceedings of 1994 20th Annual Northeast Bioengineering Conference","volume":"35 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1994-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128373876","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Application of genetic optimization to medical image segmentation","authors":"R. Cornely, W. Kuklinski","doi":"10.1109/NEBC.1994.305171","DOIUrl":"https://doi.org/10.1109/NEBC.1994.305171","url":null,"abstract":"A number of important problems in medical imaging can be classified as segmentation problems. These segmentation problems can be formulated as configurational optimization problems by representing the configurations of interest in an image as unique subsets of the complete image. An effective segmentation optimization algorithm must determine the specific image subset that best exhibits an a priori set of quantitative characteristics. Here, a genetic optimization algorithm was used to produce a population of individual sub-images that were tested via a quantitative objective function, ranked using a linear fitness and decrement scheme, and modified using a genetic cross-over operator. The algorithm was found to converge within 25 to 50 generations to a good fit to the targeted configuration in a robust and efficient manner.<<ETX>>","PeriodicalId":117140,"journal":{"name":"Proceedings of 1994 20th Annual Northeast Bioengineering Conference","volume":"42 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1994-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131889443","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Effects of current frequency, fiber orientation and sample thickness on the measured resistivity of skeletal muscle","authors":"C. Najarian, S. Kun, R. Peura","doi":"10.1109/NEBC.1994.305156","DOIUrl":"https://doi.org/10.1109/NEBC.1994.305156","url":null,"abstract":"Impedance measurements are being used as a noninvasive method for evaluation of tissue characteristics. However, the challenge is that there is no known unique correlation between the electrical behavior of tissues and their physiological parameters. The purpose of this research is to establish the groundwork that would lead to this correlation, by investigating the electrical properties of biological tissue. Experimental measurements were conducted on excised canine muscle samples using PC controlled instrumentation. The resistivity of the skeletal muscle was measured at various frequencies, angles between the fiber orientation and electrode axis, and sample thicknesses.<<ETX>>","PeriodicalId":117140,"journal":{"name":"Proceedings of 1994 20th Annual Northeast Bioengineering Conference","volume":"43 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1994-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133144697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"In vitro testing and evaluation of intraaortic and extraaortic balloon counterpulsation devices","authors":"J. Izzo, S. Gabbay, C. Mayott","doi":"10.1109/NEBC.1994.305154","DOIUrl":"https://doi.org/10.1109/NEBC.1994.305154","url":null,"abstract":"The primary purpose of this project was to develop an in vitro environment in which the intraaortic balloon pump and extraaortic balloon pump could be tested and evaluated. This was done by modifying a mechanical heart simulator to accommodate both devices, and developing a software system that could collect and process the data relevant to the operation of the two balloons.<<ETX>>","PeriodicalId":117140,"journal":{"name":"Proceedings of 1994 20th Annual Northeast Bioengineering Conference","volume":"37 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1994-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129135348","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}