Endocrine Practice最新文献

{"title":"Impact of Hybrid Continuous Glucose Monitoring on Glycemic Control in a Medical Intensive Care Unit.","authors":"Eileen R Faulds, Melanie Natasha Rayan, Molly McNett, Matthew Exline, Laureen Jones, Abigail Shoben, Chyongchiou J Lin, Brooke Lee, Amanie Rasul, Kathleen M Dungan","doi":"10.1016/j.eprac.2026.08.021","DOIUrl":"10.1016/j.eprac.2026.08.021","url":null,"abstract":"<p><strong>Objective: </strong>Continuous glucose monitoring (CGM) offers real-time glucose data that may improve dysglycemia detection in critically ill patients; however, evidence supporting its clinical effectiveness in the intensive care unit (ICU) remains limited. The objective of this study was to evaluate whether a nurse-driven hybrid continuous glucose monitoring plus point-of-care (POC) validation protocol improves glycemic outcomes compared with standard POC monitoring alone among medical ICU patients receiving continuous intravenous (IV) insulin.</p><p><strong>Methods: </strong>In this single-center prospective intervention cohort study, 100 medical ICU (MICU) patients receiving continuous IV insulin were monitored using a hybrid CGM+POC protocol and compared with 100 matched historical controls. The primary outcome was % time in glucose range (70-180 mg/dL) during continuous IV insulin therapy, calculated using POC values (at least every 4 h) for between-group comparisons. Secondary outcomes included % time in additional glucose ranges, hyperglycemia (>250 and > 400 mg/dL), and hypoglycemia (<70 and < 54 mg/dL).</p><p><strong>Results: </strong>Compared with controls, CGM-managed patients achieved an increased time in range (76% ± 18 vs 64% ± 21; P < .001) with persistent improvement after adjusting for confounders and marked reductions in severe hyperglycemia (>250 mg/dL: 6% ± 11 vs 17% ± 18; >300 mg/dL: 2.7 ± 0.6% vs 11.3 ± 1.4%; P < .001 for both). Hypoglycemic events were infrequent and similar between groups. A total of 3590 temporally matched CGM-POC pairs were available for analysis.</p><p><strong>Conclusion: </strong>In this prospective MICU cohort, real-time hybrid CGM use improved glycemic control and reduced severe hyperglycemia without increasing hypoglycemia, supporting further evaluation of structured CGM integration in critical care practice.</p>","PeriodicalId":11682,"journal":{"name":"Endocrine Practice","volume":" ","pages":""},"PeriodicalIF":4.4,"publicationDate":"2026-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148890959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Patient Redistribution Across Risk Categories in Differentiated Thyroid Cancer Using the 2025 Versus 2015 American Thyroid Association Risk Stratification Systems.","authors":"Lina Pedraza Sanchez, Larry Grullon-Polanco, Kristen J Otto, Caitlin McMullen, Prerna Dogra, Elio Monsour, Sarimar Agosto Salgado, Deepa Danan, Syeda Mahrukh Naqvi, Bruce M Wenig, Christine H Chung, Colleen Veloski, Valentina D Tarasova","doi":"10.1016/j.eprac.2026.08.019","DOIUrl":"https://doi.org/10.1016/j.eprac.2026.08.019","url":null,"abstract":"<p><strong>Objective: </strong>The 2025 American Thyroid Association (ATA) guidelines for differentiated thyroid cancer (DTC) expanded and refined the risk stratification system (RSS). The extent of patient redistribution across risk categories and the clinicopathologic drivers of reclassification remain unclear.</p><p><strong>Methods: </strong>We conducted a retrospective study of adult DTC patients who underwent thyroid surgery at a tertiary cancer center between 1999 and 2025. The 2015 and 2025 ATA RSS criteria were applied to the same cohort using R-based algorithms. Patient migration across risk categories and clinicopathologic factors associated with reclassification were analyzed descriptively.</p><p><strong>Results: </strong>A total of 843 patients with DTC (papillary, follicular, oncocytic, high grade, poorly differentiated) were included in the study. Most patients with DTC (669; 79.4%) remained in the same risk category, while 174 (20.6%) migrated to a different one. Among 2015 ATA low-risk patients, 105 (12.6%) were reclassified to higher-risk categories by the 2025 ATA RSS, including 84 to the low-intermediate group and 21 to the intermediate-high group. Additionally, 69 patients (8.2%) were reclassified from the 2015 intermediate-risk category to the 2025 high-risk category. Consequently, under the 2025 ATA RSS, the proportion of low-risk patients decreased by 29.7%, whereas the 2025 ATA intermediate-risk (low-intermediate and intermediate-high) and high-risk groups increased by 9.6% and 8.2%, respectively. No downward reclassification was observed.</p><p><strong>Conclusion: </strong>Application of the 2025 ATA RSS resulted in upward reclassification. The clinical implications of this redistribution remain to be validated, and further work is needed to correlate the revised risk categories with recurrence rates and disease-specific outcomes.</p>","PeriodicalId":11682,"journal":{"name":"Endocrine Practice","volume":" ","pages":""},"PeriodicalIF":4.4,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148872752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Conversation with Dr. Guillermo Umpierrez: Ketosis-Prone Type 2 Diabetes Mellitus: 3 Decades of Clinical, Pathophysiologic, and Therapeutic Insights","authors":"M. Cecilia Lansang MD, MPH,&nbsp;Guillermo Umpierrez MD","doi":"10.1016/j.eprac.2026.08.002","DOIUrl":"10.1016/j.eprac.2026.08.002","url":null,"abstract":"","PeriodicalId":11682,"journal":{"name":"Endocrine Practice","volume":"32 9","pages":"Pages 1438-1440"},"PeriodicalIF":4.4,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148859429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Influence of Gender-Affirming Hormone Therapy, With or Without Pubertal Suppression, on Sexual Function in Adults: A Pilot Study","authors":"Jamie L. Finegan BA,&nbsp;Jennifer T. Anger MD,&nbsp;Kyle Okamuro BS,&nbsp;Ron S. Newfield MD,&nbsp;Maja Marinkovic MD","doi":"10.1016/j.eprac.2026.04.012","DOIUrl":"10.1016/j.eprac.2026.04.012","url":null,"abstract":"<div><h3>Objective</h3><div>Gender-affirming medical therapy (GAMT), including pubertal suppression with gonadotropin-releasing hormone agonists (GnRHa) and gender-affirming hormone therapy (GAHT), is a key component of care for many transgender and gender diverse (TGD) individuals. Although hormonal impacts on physical changes are well documented, effects of GAHT compared with GnRHa + GAHT on sexual function and desire remain underexplored.</div></div><div><h3>Methods</h3><div>The present study assessed sexual function and desire in TGD adults using the validated Changes in Sexual Functioning Questionnaire 14. Participants were recruited from 2 clinical sites and grouped by GAMT type: GAHT alone or GnRHa + GAHT.</div></div><div><h3>Results</h3><div>A total of 58 participants (24 assigned female at birth, 34 assigned male at birth; mean age 22 years, range 18-25) were enrolled and their responses were analyzed. Survey questions were grouped into 5 domains of sexual functioning and scored as outlined by the instrument’s developers. Overall, there were no significant differences in sexual function between individuals who received GAHT alone and those who also received pubertal suppression with GnRHa. However, assigned male at birth participants exhibited significantly higher rates of decreased sexual function compared with assigned female at birth individuals across most domains, including desire (<em>P</em> = .021), arousal (<em>P</em> = .040), and orgasm (<em>P</em> &lt; .001).</div></div><div><h3>Conclusions</h3><div>Our pilot study suggests that pubertal suppression with GnRHa was not associated with sexual function compared with GAHT alone. Further research with larger, diverse samples and longitudinal design is warranted to better understand the long-term effects of GAMT on sexual health. This study highlights the need for inclusive sexual health assessments and improved tools tailored to TGD populations.</div></div>","PeriodicalId":11682,"journal":{"name":"Endocrine Practice","volume":"32 9","pages":"Pages 1395-1400"},"PeriodicalIF":4.4,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147766072","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Deep Dive Into Endocrine and Reproductive Health in Patients With Cystic Fibrosis: Before and Beyond Solid Organ Transplantations","authors":"Maheswaran Dhanasekaran MD,&nbsp;Basma Ataallah MD,&nbsp;Jawairia Shakil MD,&nbsp;Bhargavi Patham MD","doi":"10.1016/j.eprac.2026.04.006","DOIUrl":"10.1016/j.eprac.2026.04.006","url":null,"abstract":"<div><div>Patients with cystic fibrosis often have significant baseline endocrine comorbidities that may worsen following organ transplantation, necessitating long-term surveillance, and close follow-up. Post-transplant glycemic control is critical due to the risk of worsening cystic fibrosis-related diabetes or new-onset post-transplant diabetes mellitus associated with glucocorticoids, calcineurin inhibitors, and additional metabolic stressors. Poor glycemic control is linked to increased rates of hospitalization, graft dysfunction, rejection, morbidity, and mortality. Intensive patient education, close glucose monitoring, and timely initiating or escalating antidiabetes medication use are fundamental care goals. Cystic fibrosis also increases baseline osteoporosis and fracture risk due to gonadal dysfunction, chronic malabsorption, and frequent GC use, which may be further exacerbated post-transplant due to additional insults from high dose GCs and immunosuppression. Routine assessment on bone health, including bone mineral density and vitamin D monitoring, is essential to prevent osteoporosis and reduce fracture risk. In addition, adrenal insufficiency remains an under-recognized complication related to prolonged GC use, and clinicians should maintain a lower threshold to actively screen for adrenal insufficiency routine visits. Furthermore, post-transplant improvements in fertility and increased use of assisted reproductive technologies underscore the growing need for comprehensive, multidimensional monitoring protocols. Optimizing endocrine health and providing structured preconception counseling are essential to prevent unplanned post-transplant pregnancies and mitigating adverse maternal and fetal outcomes. This comprehensive review explores key challenges in endocrine care among patients with cystic fibrosis, with special emphasis on post-transplant patients, including glycemic control, bone health, adrenal and thyroid dysfunction, and reproductive endocrine management.</div></div>","PeriodicalId":11682,"journal":{"name":"Endocrine Practice","volume":"32 9","pages":"Pages 1409-1418"},"PeriodicalIF":4.4,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147766064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Incidence and Predictors of Acute Pancreatitis in Patients With Diabetic Ketoacidosis (DKA) and Hyperosmolar Hyperglycemic State (HHS): A Multicenter Retrospective Study","authors":"Eunae Cho MD, PhD,&nbsp;Jun Hyung Lee MD,&nbsp;Ga Ram You MD,&nbsp;Min Woo Chung MD,&nbsp;Gihyun Kim MD,&nbsp;Se Woo Park MD, PhD,&nbsp;Maira Haque MD,&nbsp;Rodger A. Liddle MD,&nbsp;Chang Hwan Park MD, PhD","doi":"10.1016/j.eprac.2026.04.015","DOIUrl":"10.1016/j.eprac.2026.04.015","url":null,"abstract":"<div><h3>Objectives</h3><div>Acute pancreatitis (AP) complicates hyperglycemic crisis, yet incidence and predictors remain unclear. We evaluated the incidence and predictors of AP in patients with diabetic ketoacidosis (DKA) and hyperosmolar hyperglycemic state (HHS).</div></div><div><h3>Methods</h3><div>This retrospective multicenter study included patients with hyperglycemic crisis between January 2015 and August 2025 at 3 tertiary hospitals. DKA/HHS and AP were diagnosed per American Diabetes Association and revised Atlanta criteria, respectively. Multivariable analysis was performed for the total cohort and DKA subgroup.</div></div><div><h3>Results</h3><div>Among 406 patients (303 with DKA, 103 with HHS), 60 (14.8%) developed AP, more frequently in DKA than in HHS (17.5% vs6.8%). Patients with AP more often presented with abdominal pain and shock and had higher serum γ-glutamyl transferase (γ-GTP) and triglyceride levels. Higher body mass index, abdominal pain, shock, elevated γ-GTP, and hypertriglyceridemia independently predicted AP. In the DKA subgroup, alcohol consumption, type 2 diabetes, abdominal pain, shock, and γ-GTP were independent predictors. While AP was associated with increased intensive care unit admission, it did not result in increased hospital stay or in-hospital mortality.</div></div><div><h3>Conclusion</h3><div>AP occurs in a substantial proportion of hyperglycemic crises. Its development is linked to specific metabolic and hemodynamic stressors, suggesting a multifactorial pathophysiology.</div></div>","PeriodicalId":11682,"journal":{"name":"Endocrine Practice","volume":"32 9","pages":"Pages 1369-1377"},"PeriodicalIF":4.4,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147812523","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Response to Letter “Perioperative Implications of Belzutifan Therapy in HIF2A-Related Pheochromocytoma and Paraganglioma”","authors":"Hussam Alkaissi MD, MS,&nbsp;Karel Pacak MD, PhD, DSc, FACE","doi":"10.1016/j.eprac.2026.07.009","DOIUrl":"10.1016/j.eprac.2026.07.009","url":null,"abstract":"","PeriodicalId":11682,"journal":{"name":"Endocrine Practice","volume":"32 9","pages":"Pages 1445-1446"},"PeriodicalIF":4.4,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148469665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk Factors for Prolonged Hospital Stay and 90-Day Readmission After Thyroidectomy in the Pediatric Population: A Nationwide Readmissions Database 2016-2020 Analysis","authors":"Jyun-Ming Huang MD,&nbsp;Chen-Sheng Huang MD","doi":"10.1016/j.eprac.2026.04.001","DOIUrl":"10.1016/j.eprac.2026.04.001","url":null,"abstract":"<div><h3>Objectives</h3><div>Thyroidectomy in children, though uncommon, is indicated for malignancies, benign goiters, and hyperthyroidism. While generally safe, concerns remain regarding postoperative complications, prolonged hospitalization, and readmission. However, large-scale data on risk factors for these outcomes in pediatric patients are limited. This study aimed to identify factors associated with prolonged hospital stay and 90-day readmission using a nationally representative database.</div></div><div><h3>Methods</h3><div>Data from the Nationwide Readmissions Database from 2016 to 2020 were retrospectively analyzed. Children 1-19 year old who underwent thyroidectomy were included in this study. Prolonged length of stay (LOS) was defined as LOS at or above the 75th percentile. Multivariable logistic regression using backward selection identified factors independently associated with prolonged LOS and 90-day readmission.</div></div><div><h3>Results</h3><div>A total of 871 pediatric thyroidectomy cases were identified, representing 2081 weighted admissions. The mean age of the patients was 14.6 years, and 75% were female. Total thyroidectomy (adjusted odds ratio [aOR] = 2.61), emergent surgery (aOR = 2.58), diabetes mellitus (aOR = 2.55), postoperative hypocalcemia (aOR = 3.05), and respiratory failure (aOR = 10.37) were associated with prolonged LOS. Factors associated with increased risk of 90-day readmission were male sex (aOR = 2.80), total thyroidectomy (aOR = 2.65), autoimmune disease (aOR = 3.28), postoperative hypocalcemia (aOR = 1.90), and postprocedural pain (aOR = 3.33).</div></div><div><h3>Conclusions</h3><div>This study identified key risk factors for prolonged hospitalization and readmission after thyroidectomy in children. These findings may support tailored perioperative strategies to improve outcomes and optimize health care resource utilization in this population.</div></div>","PeriodicalId":11682,"journal":{"name":"Endocrine Practice","volume":"32 9","pages":"Pages 1333-1339"},"PeriodicalIF":4.4,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147662411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cystic Fibrosis–Related Diabetes: Pathophysiology, Spectrum of Glycemic Abnormalities, and Evolving Approaches to Screening","authors":"Jennifer Apsan MD,&nbsp;Kajal Gandhi DO, MPH,&nbsp;Juan Pablo Perdomo Rodriguez MD,&nbsp;Mónica E. Bianco MD,&nbsp;Sara K. Bartz MD,&nbsp;Christine L. Chan MD","doi":"10.1016/j.eprac.2026.04.016","DOIUrl":"10.1016/j.eprac.2026.04.016","url":null,"abstract":"<div><div>Cystic fibrosis–related diabetes (CFRD) is a well-recognized and increasingly prevalent complication of cystic fibrosis (CF), most frequently developing in adolescence and adulthood. CFRD is associated with pulmonary function decline, poor nutritional status, and increased infection risk, and contributes to increased morbidity and mortality. The objective of this review is (1) to provide a summary of CFRD pathophysiology, highlighting the spectrum of glycemic abnormalities preceding development of CFRD, and (2) to review CFRD screening guidelines, including a narrative review of the current evidence for different CFRD screening approaches. We also review challenges to screening and important considerations in the setting of novel CF therapeutics and increasing longevity in this population.</div></div>","PeriodicalId":11682,"journal":{"name":"Endocrine Practice","volume":"32 9","pages":"Pages 1401-1408"},"PeriodicalIF":4.4,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147812514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association Between Clinical Factors and Postoperative Hypoglycemia in Pheochromocytoma and Paraganglioma: A Retrospective Cohort Study","authors":"Yuke Li MM,&nbsp;Wencong Han MD,&nbsp;Yujian Cui MM,&nbsp;Jinwei Wang PhD,&nbsp;Zheng Zhang MD,&nbsp;Nan Li MD","doi":"10.1016/j.eprac.2026.04.009","DOIUrl":"10.1016/j.eprac.2026.04.009","url":null,"abstract":"<div><h3>Objectives</h3><div>This study aimed to investigate the correlation between clinical factors and postoperative hypoglycemia in pheochromocytoma and paraganglioma (PPGL).</div></div><div><h3>Methods</h3><div>This retrospective cohort study included adult patients who underwent PPGL surgery with pathologic confirmation. The primary endpoint was the occurrence of postoperative hypoglycemia. Pre- and intraoperative clinical variables were collected. Independent risk factors for postoperative hypoglycemia were identified using multivariate logistic regression analysis, and a predictive model along with a nomogram was constructed and validated.</div></div><div><h3>Results</h3><div>A total of 346 PPGL patients were enrolled. Postoperative hypoglycemia occurred in 45 patients (13.0%), with 35 cases (83.3%) occurring within 24 h after surgery. Multivariate analysis identified age &lt; 30 years (odds ratio [OR] 3.091, 95% confidence interval [CI] 1.145-8.344, <em>P</em>= .026), history of chronic kidney disease (OR 3.253, 95% CI 1.213-8.725, <em>P</em>= .019), preoperative typical symptoms (defined as the presence of at least one of the classic triad: headaches, palpitations, or sweating) (OR 2.207, 95% CI 1.119-4.355, <em>P</em>= .022), preoperative positive semi-quantitative urine glucose (OR 2.986, 95% CI 1.063-8.390, <em>P</em>= .038), and adrenal tumor (OR 3.224, 95% CI 1.208-8.604, <em>P</em>= .019) as independent risk factors for postoperative hypoglycemia. The area under the receiver operating characteristic curve for the predictive model was 0.734 (95% CI 0.659-0.809). Calibration plots suggested good consistency between the predicted and actual risk. The final model was visualized via a nomogram.</div></div><div><h3>Conclusions</h3><div>Clinical factors were independently associated with the occurrence of postoperative hypoglycemia in PPGL. The visual nomogram developed in this study aided in predicting the risk of postoperative hypoglycemia in PPGL patients.</div></div>","PeriodicalId":11682,"journal":{"name":"Endocrine Practice","volume":"32 9","pages":"Pages 1387-1394"},"PeriodicalIF":4.4,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147728757","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}