Ejso最新文献

{"title":"Advert ESSO Congress 2025","authors":"","doi":"10.1016/S0748-7983(25)00831-5","DOIUrl":"10.1016/S0748-7983(25)00831-5","url":null,"abstract":"","PeriodicalId":11522,"journal":{"name":"Ejso","volume":"51 9","pages":"Article 110403"},"PeriodicalIF":2.9,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144996225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reply to: In reference to “A pilot study evaluating the feasibility of enriching and detecting circulating tumour cells from peripheral and ovarian veins in rare epithelial ovarian carcinomas”","authors":"Faye Lewis , Mark P. Ward , Feras Abu Saadeh , John J. O'Leary , Sharon A. O'Toole","doi":"10.1016/j.ejso.2025.110206","DOIUrl":"10.1016/j.ejso.2025.110206","url":null,"abstract":"","PeriodicalId":11522,"journal":{"name":"Ejso","volume":"51 9","pages":"Article 110206"},"PeriodicalIF":2.9,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144293545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reply to: Comment on “Postoperative quality of life in patients with early-stage cervical cancer: A prospective 10-year follow-up study”","authors":"Katerina Maxova M.D., Michael J. Halaska M.D., Ph.D.","doi":"10.1016/j.ejso.2025.110256","DOIUrl":"10.1016/j.ejso.2025.110256","url":null,"abstract":"","PeriodicalId":11522,"journal":{"name":"Ejso","volume":"51 9","pages":"Article 110256"},"PeriodicalIF":2.9,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144539580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Breaking the scalpel ceiling: Persistent barriers faced by female surgeons in modern surgical practice.","authors":"Adele Ketley, Jenna Morgan","doi":"10.1016/j.ejso.2025.110423","DOIUrl":"https://doi.org/10.1016/j.ejso.2025.110423","url":null,"abstract":"<p><p>Despite female medical students and newly qualifying doctors now outnumbering males, surgery remains a male-dominated specialty. Whilst numbers of female within surgical specialties continue to rise, they still lag behind other specialties, even though women have equivalent or better surgical outcomes than their male counterparts. Reasons for this under representation are multifactorial, but include historic cultural issues, lack of representation, sexism, misogyny, sexual misconduct and challenges with pregnancy and childcare, that disproportionally affect female surgeons. Cancer surgery has traditionally been male dominated, often involving complex, lengthy surgery and is often a very competitive career. However, the data suggests that female surgeons have greater empathy, sensitivity and communication skills, which are assets in this often emotionally charged area of practice. This article presents an overview of these issues and calls for systemic reform and a cultural shift in surgical specialties to address these barriers.</p>","PeriodicalId":11522,"journal":{"name":"Ejso","volume":" ","pages":"110423"},"PeriodicalIF":2.9,"publicationDate":"2025-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145039340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Women surgeons: Are they Better?: Narrative review.","authors":"Natsumi Saka, Jun Watanabe","doi":"10.1016/j.ejso.2025.110421","DOIUrl":"https://doi.org/10.1016/j.ejso.2025.110421","url":null,"abstract":"<p><p>Surgery has historically been a male-dominated field; however, the representation of female surgeons has steadily increased, necessitating a comprehensive review of comparative performance. This narrative review synthesises recent literature to evaluate male and female surgeons across several key domains: technical skills, non-technical abilities, patient outcomes, and academic contributions. In terms of technical skills, research presents nuanced findings. While some studies suggest a potential male advantage in visuospatial skills, other evidence indicates that these initial differences can be mitigated or eliminated through dedicated training and prior experience with activities such as video games. Conversely, female surgeons consistently demonstrate superior manual dexterity. In non-technical areas, female surgeons consistently receive higher patient scores for communication, including providing clear explanations, listening attentively, and dedicating sufficient time during consultations. The literature on patient outcomes is complex and sometimes contradictory. Several large-scale observational studies and meta-analyses have reported a small but statistically significant reduction in mortality for patients treated by female surgeons, whereas other research has found no such association. Despite these findings, female surgeons remain underrepresented in senior academic and organisational leadership roles, with persistent disparities in departmental chair positions and grant funding. This gap is not necessarily attributable to a lack of productivity but rather to insufficient mentorship and institutional support. The evidence highlights that individual qualities and training are more significant than gender, although persistent systemic biases continue to pose challenges to female surgeons' career advancement and patient trust. Addressing these prejudices is essential to fostering a safe and equitable environment for all.</p>","PeriodicalId":11522,"journal":{"name":"Ejso","volume":" ","pages":"110421"},"PeriodicalIF":2.9,"publicationDate":"2025-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145039327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Future perspectives of cancer surgery in AI healthcare transformation: A call for surgeon leadership, ethical direction, and scientific rigor.","authors":"Monica Ortenzi, Pietro Mascagni, Young-Woo Kim","doi":"10.1016/j.ejso.2025.110418","DOIUrl":"https://doi.org/10.1016/j.ejso.2025.110418","url":null,"abstract":"","PeriodicalId":11522,"journal":{"name":"Ejso","volume":" ","pages":"110418"},"PeriodicalIF":2.9,"publicationDate":"2025-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145063372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rethinking TNM: Tumor deposit-based prognostic models may improve N-staging in colorectal cancer","authors":"Simon Lundström ,&nbsp;Erik Agger ,&nbsp;Marie-Louise Lydrup ,&nbsp;Fredrik Jörgren ,&nbsp;Pamela Buchwald","doi":"10.1016/j.ejso.2025.110420","DOIUrl":"10.1016/j.ejso.2025.110420","url":null,"abstract":"<div><h3>Introduction</h3><div>Tumor deposits are an important negative prognostic factor for long-term oncological outcomes in colorectal cancer patients, independent of lymph node status. Several novel models have been proposed to further integrate tumor deposits into the TNM-staging system, but their comparative performance remains unclear. The aim of this study was to identify, compare and validate novel prognostic models incorporating tumor deposits for N-stage classification.</div></div><div><h3>Methods</h3><div>A scoping literature review identified novel prognostic models that incorporated tumor deposits or tumor deposit count into N-staging. The identified models were validated using patient data from the Swedish Colorectal Cancer Registry, assessing overall survival, distant metastasis, and local recurrence. Prognostic performance was compared to the TNM N-staging using Kaplan-Meier curves for visual analysis, Harrell's C-index for discriminative ability, and Bayesian information criterion for model fit.</div></div><div><h3>Results</h3><div>Of 792 articles, seventeen met the inclusion criteria, resulting in ten unique models in addition to TNM. For the patient cohort, 26,970 patients remained after exclusion, of whom 3,312 (12 %) had tumor deposits. All models were superior to TNM with two models standing out; an integrated model combining lymph node and tumor deposit count, and a ratio model considering number of tumor deposits, positive lymph nodes, and total number of extracted nodal structures. All models provided prognostic value, but differences were modest.</div></div><div><h3>Conclusion</h3><div>This study demonstrated that although all models outperformed TNM, prognostic differences between the models were small. While tumor deposits provide valuable prognostic information for high-risk patients, additional risk factors are required to further enhance the staging system.</div></div>","PeriodicalId":11522,"journal":{"name":"Ejso","volume":"51 11","pages":"Article 110420"},"PeriodicalIF":2.9,"publicationDate":"2025-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144996881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of tumor size on oncological and surgical outcomes in robot-assisted transaxillary surgery for papillary thyroid carcinoma","authors":"Piermarco Papini,&nbsp;Leonardo Rossi,&nbsp;Leonardo Russo,&nbsp;Chiara Becucci,&nbsp;Andrea De Palma,&nbsp;Carlo Enrico Ambrosini,&nbsp;Marco Puccini,&nbsp;Gabriele Materazzi","doi":"10.1016/j.ejso.2025.110422","DOIUrl":"10.1016/j.ejso.2025.110422","url":null,"abstract":"<div><h3>Background</h3><div>Robot-assisted transaxillary thyroidectomy (RATT) has emerged as a remote access approach for differentiated thyroid carcinoma (DTC), yet data on its oncological efficacy for tumors larger than 3 cm, particularly in European cohorts, remain scarce. This study aimed to evaluate surgical and oncological outcomes of RATT in patients with papillary thyroid carcinoma (PTC), stratified by tumor size.</div></div><div><h3>Materials and methods</h3><div>We retrospectively reviewed 270 patients with histologically confirmed PTC who underwent RATT between July 2012 and August 2022 at a single tertiary center. Patients were categorized into two groups based on tumor size: Group A (&lt;3 cm, n = 226) and Group B (≥3 cm, n = 44). Surgical outcomes, complication rates, and oncological parameters—including serum thyroglobulin (Tg) levels, anti-thyroglobulin antibodies, and structural recurrence—were analyzed. Subgroup analysis was conducted based on radioiodine ablation (RAI) status.</div></div><div><h3>Results</h3><div>No significant differences were observed between groups in terms of operative time, hospital stay, or postoperative complications. Tg levels after RAI were comparable between Group A and Group B (p = 0.999), indicating similar biochemical response. Only one patient experienced structural recurrence during follow-up (mean: 48 ± 31 months). Patients who underwent lobectomy alone showed no evidence of recurrence regardless of tumor size. No independent predictors of Tg levels were identified.</div></div><div><h3>Conclusions</h3><div>RATT appears to be a safe and oncologically effective approach for PTC, even for tumors ≥3 cm. These findings support the broader use of RATT in selected patients, with outcomes comparable across tumor sizes. Further multicenter studies with longer follow-up are warranted to validate these results.</div></div>","PeriodicalId":11522,"journal":{"name":"Ejso","volume":"51 11","pages":"Article 110422"},"PeriodicalIF":2.9,"publicationDate":"2025-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144996948","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Selection for local treatment and outcomes of surgical resection in patients with synchronous colorectal liver metastases: A nationwide population-based study","authors":"Michelle R. de Graaff ,&nbsp;Joost M. Klaase ,&nbsp;Macel den Dulk ,&nbsp;Dirk J. Grünhagen ,&nbsp;R.-J. Swijnenburg ,&nbsp;G. Kazemier ,&nbsp;M. Liem ,&nbsp;E.J.T. Belt ,&nbsp;M. Vermaas ,&nbsp;J.S.D. Mieog ,&nbsp;P. Gobardhan ,&nbsp;A. Rijken ,&nbsp;S.J. Oosterling ,&nbsp;K. Bosscha ,&nbsp;Niels F.M. Kok ,&nbsp;MarloesA.G. Elferink","doi":"10.1016/j.ejso.2025.110411","DOIUrl":"10.1016/j.ejso.2025.110411","url":null,"abstract":"<div><h3>Background</h3><div>The aim of this study was to evaluate potential disparities in the probability of undergoing surgical treatment among patients with synchronous colorectal liver metastases (CRLM) and to investigate which non-tumour-related characteristics influenced postoperative outcomes.</div></div><div><h3>Methods</h3><div>This was a population-based study of all patients diagnosed with synchronous CRLM between 2015 and 2021 in the Netherlands. Data were retrieved from the Netherlands Cancer Registry (NCR) and data of patients who underwent surgical exploration were retrieved from the Dutch Hepato Biliary Audit (DHBA). The association between non-tumour-related factors, the chance of getting local treatment of CRLM and outcomes after resection were evaluated using multivariable logistic regression models.</div></div><div><h3>Results</h3><div>From the NCR, 14,047 patients with synchronous CRLM were included. Of these 2753 (20 %) patients underwent local treatment of CRLM. Non-tumour-related factors associated with a lower likelihood of local treatment of CRLM included age (OR 0.94 95 %CI 0.94–0.95) and female sex (OR 0.87, 95 %CI 0.78–0.97). Middle and high Socioeconomic status (SES) compared to low SES (respectively OR 1.35, 95 %CI 1.18–1.54 and OR 1.61, 95 %CI 1.41–1.84) and presentation in a hospital that performed liver surgery (OR 1.52, 95 %CI 1.26–1.84) were associated with a higher likelihood of getting local treatment. From the DHBA 2535 patients were included. Non-tumour-related factors associated with both major morbidity and mortality included age (OR 1.01 95 %CI 1.00–1.03 and OR 1.07, 95 %CI 1.02–1.11, respectively) and ASA-score ≥3 (OR 1.7,95 %CI 1.34–2.29 and OR 2.88, 95 CI 1.92–1.11) respectively.</div></div><div><h3>Conclusion</h3><div>In addition to tumour-related factors, non-tumour-related factors, including age, male sex, SES and hospital of presentation, all contributed to the likelihood of getting local treatment for CRLM. As not all these factors influence postoperative outcomes, healthcare systems should also focus on eliminating barriers to accessing appropriate care.</div></div>","PeriodicalId":11522,"journal":{"name":"Ejso","volume":"51 11","pages":"Article 110411"},"PeriodicalIF":2.9,"publicationDate":"2025-08-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145205956","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Outcomes following exploratory surgery without subsequent resection in perihilar cholangiocarcinoma: A nationwide analysis","authors":"Julien A. Luyten ,&nbsp;Lydia G. van der Geest ,&nbsp;Steven W.M. Olde Damink ,&nbsp;Frank G. Schaap ,&nbsp;Bas Groot Koerkamp ,&nbsp;Marjolein Y.V. Homs ,&nbsp;Joris I. Erdmann ,&nbsp;Willem F. Brandts ,&nbsp;Joanne Verheij ,&nbsp;Frederik J.H. Hoogwater ,&nbsp;Jeroen Hagendoorn ,&nbsp;Jelmer E. Oor ,&nbsp;Robert C. Verdonk ,&nbsp;Iryna V. Samarska ,&nbsp;Razvan L. Miclea ,&nbsp;Jan Bednarsch ,&nbsp;Ulf P. Neumann ,&nbsp;Judith de Vos-Geelen ,&nbsp;Maxime J.L. Dewulf ,&nbsp;Dutch Hepatocellular and Cholangiocarcinoma Group","doi":"10.1016/j.ejso.2025.110419","DOIUrl":"10.1016/j.ejso.2025.110419","url":null,"abstract":"<div><h3>Introduction</h3><div>Definitive assessment of resectability in perihilar cholangiocarcinoma (pCCA) often requires surgical exploration. Limited data exist on whether surgical exploration without resection affects the chance of receiving subsequent systemic therapy and survival. This nationwide analysis aims to address this question.</div></div><div><h3>Methods</h3><div>Patients diagnosed with non-metastatic pCCA between 2012 and 2023 were selected from the Netherlands Cancer Registry and categorized as resected, explored (surgical exploration without resection), or non-explored (non-metastatic tumours without exploration or resection). Overall survival data was stratified by systemic therapy use.</div></div><div><h3>Results</h3><div>The cohort included 2014 patients of which 490 patients (24.3 %) underwent resection, 258 patients (12.8 %) underwent surgical exploration without resection, and 1266 patients (62.9 %) were not explored. Overall, 90-day mortality following exploration was 19.5 %. Among explored patients, 38.0 % (98/258) received systemic therapy compared to 10.6 % (134/1266) of non-explored patients (p &lt; 0.001). With systemic therapy, explored patients had a median overall survival (mOS) of 14.3 months (95 % CI 12.7–18.2) from diagnosis compared to 12.8 months (95 % CI 11.6–15.8) for non-explored patients (p = 0.350). With best supportive care, explored patients had a mOS of 8.1 months (95 % CI 6.5–10.3) compared to 3.2 months (95 % CI 2.8–3.7) for non-explored patients (p ≤ 0.001).</div></div><div><h3>Conclusion</h3><div>Among patients with non-metastatic pCCA receiving systemic therapy, survival outcomes are comparable between those who undergo surgical exploration and those who do not. Despite a possible impact on quality of life, these findings suggest that surgical exploration does not hinder access to systemic therapy or negatively affect survival.</div></div>","PeriodicalId":11522,"journal":{"name":"Ejso","volume":"51 11","pages":"Article 110419"},"PeriodicalIF":2.9,"publicationDate":"2025-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144996950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}