Ejso最新文献

{"title":"Robotic versus open level III-IV inferior vena cava thrombectomy: A multicenter, retrospective, propensity-matched analysis","authors":"Liangyou Gu ,&nbsp;Lin Yao ,&nbsp;Qingbo Huang ,&nbsp;Yonghui Chen ,&nbsp;Peng Wu ,&nbsp;Cheng Peng ,&nbsp;Huaikang Li ,&nbsp;Peng Zhang ,&nbsp;Yaoyao Zheng ,&nbsp;Baojun Wang ,&nbsp;Zhisong He ,&nbsp;Xin Ma ,&nbsp;Xu Zhang","doi":"10.1016/j.ejso.2025.110327","DOIUrl":"10.1016/j.ejso.2025.110327","url":null,"abstract":"<div><h3>Background</h3><div>The safety and efficacy of robotic inferior vena cava thrombectomy (IVCTE) for level III-IV thrombus with a comparison to open IVCTE is still unclear. This study aimed to compare robotic vs open IVCTE for renal tumors with level III-IV tumor thrombus.</div></div><div><h3>Materials and methods</h3><div>We performed a retrospective analysis of patients who underwent R-IVCTE or O-IVCTE in four academic tertiary centers between 2015 and 2023. Propensity score-matching analysis was performed. Perioperative data and prognosis were reviewed. Progression-free survival and overall survival were analyzed by Kaplan-Meier survival curve, and comparison between groups was performed by log-rank test.</div></div><div><h3>Results</h3><div>A total of 34 and 70 patients underwent R-IVCTE and O-IVCTE, respectively. After matching, baseline characteristics were comparable (30 vs 30 patients). Of the matched cohorts, robotic procedures were associated with longer operative time (508 vs 322 min; p &lt; 0.001), lower rate of cardiopulmonary bypass (33.3 % vs 66.7 %; p = 0.010), longer ICU stay (5 vs 2 days, p = 0.001), shorter postoperative hospital stay (10 vs 13 days, p = 0.021). Patients undergoing R-IVCTE had a higher level of serum aminotransferase and aspartate aminotransferase than those undergoing O-IVCTE at 1–2 days after surgery, and the difference had disappeared at 1 week after surgery. No difference was observed between the two approaches regarding estimated blood loss, complications, pathological variables and oncological outcomes.</div></div><div><h3>Conclusions</h3><div>R-IVCTE can be feasible and safe in selected cases of renal tumors with level III-IV tumor thrombus, which may achieve similar perioperative and oncological outcomes compared to O-IVCTE.</div></div>","PeriodicalId":11522,"journal":{"name":"Ejso","volume":"51 10","pages":"Article 110327"},"PeriodicalIF":3.5,"publicationDate":"2025-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144633895","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comment on “Pre-operative radiotherapy for breast cancer patients receiving mastectomy and immediate autologous tissue reconstruction”","authors":"Wei Zhang,&nbsp;Qidong Ge","doi":"10.1016/j.ejso.2025.110313","DOIUrl":"10.1016/j.ejso.2025.110313","url":null,"abstract":"","PeriodicalId":11522,"journal":{"name":"Ejso","volume":"51 10","pages":"Article 110313"},"PeriodicalIF":3.5,"publicationDate":"2025-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144632448","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis of influencing factors for achieving textbook outcome after laparoscopic right posterior sectionectomy of hepatocellular carcinoma","authors":"Changyan Zhu ,&nbsp;Jiali Wu ,&nbsp;Xiuyuan Wang ,&nbsp;Weixing Zhang ,&nbsp;Zhiqiang Fu ,&nbsp;Yuqiu Hu","doi":"10.1016/j.ejso.2025.110328","DOIUrl":"10.1016/j.ejso.2025.110328","url":null,"abstract":"<div><h3>Background</h3><div>Textbook outcome (TO) is a comprehensive indicator used to assess postoperative outcomes and quality of care. This study analyzes the incidence and influencing factors of TO after laparoscopic right posterior sectionectomy (LRPS) in hepatocellular carcinoma (HCC) patients.</div></div><div><h3>Method</h3><div>A retrospective cohort study was conducted on HCC patients who underwent LRPS at Sun Yat-sen Memorial Hospital from January 2018 to June 2023. Patients were divided into TO and non-TO groups. Univariable and multivariable logistic regression analyses identified factors influencing TO achievement.</div></div><div><h3>Result</h3><div>A total of 115 HCC patients underwent LRPS, with 70.4 % (82/115) achieving TO. Univariable logistic regression analysis identified smoking history, preoperative alanine transaminase, preoperative R-glutaminase transferase, operative time, intraoperative blood loss, blood transfusion and lymphovascular invasion as risk factors. Multivariablelogistic regression analysis revealed smoking history (OR: 9.92, 95 % CI: 2.60–37.82, P = 0.001), preoperative alanine transaminase (OR: 3.43, 95 % CI: 1.11–10.57, P = 0.032), preoperative R-glutaminase transferase (OR: 3.34, 95 % CI: 1.16–9.65, P = 0.026), and intraoperative blood loss (OR: 1.25, 95 % CI: 1.07–1.47, P = 0.005) as independent risk factors. The combined index of these factors showed the greatest predictive value for TO (AUC: 0.821, 95 % CI: 0.74–0.90, P &lt; 0.001).</div></div><div><h3>Conclusion</h3><div>TO is a reliable measure for LRPS outcomes. Factors such as no smoking history, preoperative alanine transaminase ≤50 U/L, preoperative R-glutaminase transferase ≤60 U/L, and intraoperative blood loss &lt;325 mL are associated with higher TO achievement.</div></div>","PeriodicalId":11522,"journal":{"name":"Ejso","volume":"51 10","pages":"Article 110328"},"PeriodicalIF":3.5,"publicationDate":"2025-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144654681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of PuraBond® on postoperative pain following transoral resections of primary oral or oropharyngeal neoplastic mucosal lesions: A blinded randomised controlled study (PuraBond® PROOF)","authors":"Randa Ghazal Asswad ,&nbsp;James Constable ,&nbsp;Ahmed Abdelrahman ,&nbsp;Paul Banks ,&nbsp;Zoe Mellor ,&nbsp;Terry M. Jones ,&nbsp;Richard Shaw ,&nbsp;Katharine Davies ,&nbsp;Christopher Loh ,&nbsp;Richard Jackson ,&nbsp;Andrew Schache ,&nbsp;Jason C. Fleming","doi":"10.1016/j.ejso.2025.110322","DOIUrl":"10.1016/j.ejso.2025.110322","url":null,"abstract":"<div><h3>Background</h3><div>RADA16 (PuraBond®) is a novel, synthetic agent that forms a transparent, self-assembling scaffold, mimicking human extracellular-matrix to promote haemostasis. We hypothesise this physical barrier provides effective analgesia for upper aerodigestive tract surgical wounds through nociception blockade during swallowing. This study evaluated PuraBond®’s efficacy on postoperative pain following transoral resection of oral/oropharyngeal mucosal lesions.</div></div><div><h3>Methods</h3><div>A prospective, blinded, single-centre, randomised controlled trial was conducted, comparing intraoperative PuraBond® application versus no topical agent. Patients undergoing transoral resection of dysplasia/malignancy of the oral cavity or oropharynx were recruited. Stratification factors included lesion site, electrosurgery versus laser technique, and concurrent neck dissection. The primary outcome measure was pain scores measured using a visual analogue scale over 30-days postoperatively.</div></div><div><h3>Results</h3><div>In total, 68 patients were recruited (70% oropharyngeal, 30% oral; PuraBond® n = 32, control n = 36) and analysed. Mean pain scores over the study period were 2.56 and 3.41 for PuraBond® and control groups respectively. The control arm had higher baseline adjusted pain scores at all timepoints, but none of these were individually statistically significant. Cumulative results however demonstrated a significantly greater increase in pain from preoperative baseline for the control group over the entire 30-day period (0.61, 95% CI 0.12–1.10, p = 0.016), with the most noticeable clinical difference during the initial week (0.77, 95% CI 0.18–1.36, p = 0.011). Although underpowered with regards to haemorrhage events, these were three-times lower with PuraBond® (p = 0.266).</div></div><div><h3>Conclusion</h3><div>PuraBond® use following head and neck mucosal resections is a safe and potentially useful surgical adjunct in reducing postoperative pain. The opportunity exists, via adequately-powered studies, to assess whether the trend towards reduced haemorrhage is significant and reproducible. Trial registration: NCT05773781(<span><span>https://clinicaltrials.gov</span><svg><path></path></svg></span>).</div></div>","PeriodicalId":11522,"journal":{"name":"Ejso","volume":"51 10","pages":"Article 110322"},"PeriodicalIF":3.5,"publicationDate":"2025-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144632749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Re: Optimal timing of surgery after neoadjuvant chemoradiotherapy in rectal cancer: A retrospective analysis.","authors":"Parsa Torkaman, Ali Hosseini","doi":"10.1016/j.ejso.2025.110316","DOIUrl":"https://doi.org/10.1016/j.ejso.2025.110316","url":null,"abstract":"","PeriodicalId":11522,"journal":{"name":"Ejso","volume":"51 10","pages":"110316"},"PeriodicalIF":2.9,"publicationDate":"2025-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144803793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comment on “A deep-learning model to predict the completeness of cytoreductive surgery in colorectal cancer with peritoneal metastasis”","authors":"Yibin Ma","doi":"10.1016/j.ejso.2025.110315","DOIUrl":"10.1016/j.ejso.2025.110315","url":null,"abstract":"","PeriodicalId":11522,"journal":{"name":"Ejso","volume":"51 10","pages":"Article 110315"},"PeriodicalIF":3.5,"publicationDate":"2025-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144623770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comment on: \"Muscle-specific strength predicts postoperative complications and survival in patients undergoing curative colectomy for colorectal cancer\"","authors":"Min Zou ,&nbsp;Zijie Yang ,&nbsp;Jinkai Feng ,&nbsp;Zengqiang Yang","doi":"10.1016/j.ejso.2025.110321","DOIUrl":"10.1016/j.ejso.2025.110321","url":null,"abstract":"","PeriodicalId":11522,"journal":{"name":"Ejso","volume":"51 10","pages":"Article 110321"},"PeriodicalIF":3.5,"publicationDate":"2025-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144632750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perioperative dynamic changes of systemic inflammatory biomarkers predict tumor recurrence following curative-intent resection of hepatocellular carcinoma","authors":"Jingming Lu ,&nbsp;Fumin Wang ,&nbsp;Yaoxing Ren ,&nbsp;Yu An ,&nbsp;Francesca Ratti ,&nbsp;Hugo P. Marques ,&nbsp;Silvia Silva ,&nbsp;Olivier Soubrane ,&nbsp;Vincent Lam ,&nbsp;George A. Poultsides ,&nbsp;Irinel Popescu ,&nbsp;Razvan Grigorie ,&nbsp;Sorin Alexandrescu ,&nbsp;Guillaume Martel ,&nbsp;Aklile Workneh ,&nbsp;Andrea Ruzzenente ,&nbsp;Tom Hugh ,&nbsp;Luca Aldrighetti ,&nbsp;Itaru Endo ,&nbsp;Yi Lyu ,&nbsp;Timothy M. Pawlik","doi":"10.1016/j.ejso.2025.110320","DOIUrl":"10.1016/j.ejso.2025.110320","url":null,"abstract":"<div><h3>Background</h3><div>Hepatic inflammation during liver resection induces immune dysregulation. We sought to investigate how surgical stress reshapes systemic inflammation and affects tumor recurrence following surgical resection of hepatocellular carcinoma (HCC).</div></div><div><h3>Methods</h3><div>Patients who underwent curative resection of HCC between 2000 and 2022 were identified from an international multicenter cohort. We longitudinally quantified perioperative inflammatory dynamics, particularly neutrophil-to-lymphocyte ratio (NLR) and systemic immune-inflammation index (SII). The primary endpoint was recurrence-free survival (RFS). Model performance was validated through bootstrap resampling (1000 iterations) and ROC analysis.</div></div><div><h3>Results</h3><div>A total of 745 patients were included. Among the dynamic changes of inflammation cells count, only changes in NLR at postoperative day 3 versus preoperative value (ΔNLR3) was identified as a strong predictor associated with HCC recurrence (HR 1.005, 95 % 1.002–1.009; <em>p</em> = 0.002). The optimal cutoff value of <span><math><mrow><mo>Δ</mo><mi>N</mi><mi>L</mi><mi>R</mi><mn>3</mn></mrow></math></span> was defined as 47, and patients with <span><math><mrow><mo>Δ</mo><mi>N</mi><mi>L</mi><mi>R</mi><mn>3</mn></mrow></math></span> ≥ 47 had 75 % increased risk of tumor recurrence versus individuals with <span><math><mrow><mo>Δ</mo><mi>N</mi><mi>L</mi><mi>R</mi><mn>3</mn></mrow></math></span> &lt; 47 (HR 1.75, 95 % CI 1.35–2.28, p &lt; 0.001). Moreover, <span><math><mrow><mo>Δ</mo><mi>N</mi><mi>L</mi><mi>R</mi><mn>3</mn></mrow></math></span> could be utilized in differentiating high-versus low-recurrence risk patients with early staged HCC. By combining <span><math><mrow><mo>Δ</mo><mi>N</mi><mi>L</mi><mi>R</mi><mn>3</mn></mrow></math></span> with tumor-associated risk factors, we created an <em>InfTumMod</em> model, which demonstrated very good predictive accuracy of 70 % relative to tumor recurrence within the first three years following surgical resection of HCC.</div></div><div><h3>Conclusions</h3><div>The ΔNLR3 index reflected systemic inflammation and risk of tumor recurrence. The <em>InfTumMod</em> model incorporated inflammation index and tumor characteristics, which can help identify patients at higher risk of recurrence and mortality.</div></div>","PeriodicalId":11522,"journal":{"name":"Ejso","volume":"51 10","pages":"Article 110320"},"PeriodicalIF":3.5,"publicationDate":"2025-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144604736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between the type of pre-existing adenoma and response of rectal cancer to neoadjuvant therapy","authors":"Sameh Hany Emile ,&nbsp;Nir Horesh ,&nbsp;Zoe Garoufalia ,&nbsp;Anjelli Wignakumar ,&nbsp;Michal Perets ,&nbsp;Ebram Salama ,&nbsp;Steven D. Wexner","doi":"10.1016/j.ejso.2025.110319","DOIUrl":"10.1016/j.ejso.2025.110319","url":null,"abstract":"<div><h3>Background</h3><div>Several factors influence response to neoadjuvant therapy (NAT) for locally advanced rectal cancer. One potentially relevant factor not previously studied is the type of pre-existing adenoma. We aimed to investigate the association between the type of pre-existing adenoma and response of rectal cancer to NAT and examine the tumor characteristics by adenoma type.</div></div><div><h3>Methods</h3><div>This study was a retrospective review of patients with stage II-III rectal adenocarcinomas from the NCDB (2004–2017) who underwent proctectomy after NAT. Rectal cancers were classified and compared by the type of pre-existing adenomas: villous adenoma (VA), tubular adenoma (TA), and tubulovillous adenoma (TVA)-associated carcinomas. Case-control analysis of failure of response to NAT was conducted, including type of pre-existing adenoma as a potential covariate.</div></div><div><h3>Results</h3><div>2760 patients (69.6 % male; mean age: 59.9 years) with stage II (44.8 %) or stage III (55.2 %) rectal cancers were included. Most adenomas were TVA (78.4 %), followed by VA (21.1 %) and TA (0.5 %). 55.5 % of patients showed complete response (10 %) and partial (downstaging; 45.5 %) response after NAT. 64.3 % of TA-associated rectal carcinomas failed to respond to NAT compared to 46.4 % and 43.9 % of VA and TVA-associated carcinomas, respectively (p = 0.388). Independent predictors of failure of response to NAT were stage II disease (OR: 1.85, p &lt; 0.001), high tumor grade (OR: 1.94, p = 0.007), LVI (OR: 3.34, p &lt; 0.001), PNI (OR: 1.69, p = 0.032), and elevated pretreatment CEA (OR: 1.54, p = 0.002).</div></div><div><h3>Conclusions</h3><div>TA-associated carcinomas exhibited the lowest response to NAT, although not statistically significant. Predictors for failure of response to NAT were stage II disease, high tumor grade, LVI and PNI, and elevated pretreatment CEA levels.</div></div>","PeriodicalId":11522,"journal":{"name":"Ejso","volume":"51 10","pages":"Article 110319"},"PeriodicalIF":3.5,"publicationDate":"2025-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144623768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Long term outcomes of breast primary sarcomas and malignant phyllodes tumors: 20 years observational analysis of the BEAM∗ study group. (∗the breast European association for mesenchymal tumors)","authors":"Alejandro M. Sanchez ,&nbsp;Flavia De Lauretis ,&nbsp;Angela Bucaro ,&nbsp;Chiara V. Pirrottina ,&nbsp;Niccolò Borghesan ,&nbsp;Antonio Franco ,&nbsp;Lorenzo Scardina ,&nbsp;Diana Giannarelli ,&nbsp;Alba Di Leone ,&nbsp;Riccardo Masetti ,&nbsp;Armando Orlandi ,&nbsp;Alessandra Fabi ,&nbsp;Antonella Palazzo ,&nbsp;Ilaria Poli ,&nbsp;Angela Santoro ,&nbsp;Antonino Mulè ,&nbsp;Nicoletta D’Alessandris ,&nbsp;Fabio Marazzi ,&nbsp;Valeria Masiello ,&nbsp;Valeria Verusio ,&nbsp;Jenny C. Millochau","doi":"10.1016/j.ejso.2025.110265","DOIUrl":"10.1016/j.ejso.2025.110265","url":null,"abstract":"<div><h3>Background</h3><div>Primary breast sarcomas (PBS) and malignant phyllodes tumors (MPT) represent less than 1 % of breast malignancies. Current evidence relies on heterogeneous retrospective series, resulting in controversial therapeutic approaches. This study aimed to analyze long-term outcomes in a large multicentric cohort treated with consistent strategies.</div></div><div><h3>Materials and methods</h3><div>We conducted a multicentric retrospective study involving 113 patients treated for PBS (n = 42), MPT (n = 47), and mixed cases (MC, n = 24) at 11 European breast units between 2000 and 2020. Primary endpoint was disease-free survival (DFS). Secondary endpoints included overall survival (OS), local recurrence rate (LRR), and positive margin, re-excision, and axillary involvement rates. Survival analyses were performed using the Kaplan-Meier method and log-rank test.</div></div><div><h3>Results</h3><div>With a median follow-up of 95 months, the 10-year OS, DFS, and LRR for the entire cohort were 75.2 %, 61.9 %, and 18.4 %, respectively. Mixed cases exhibited the poorest outcomes (10-year OS: 57.6 %, DFS: 46.1 %), followed by PBS (OS: 67.5 %, DFS: 46.5 %). MPT demonstrated better survival rates (OS: 89.2 %, DFS: 82.9 %). Significant survival factors included histological subtype, surgical margins, and age. Notably, adjuvant chemotherapy was linked to worse outcomes (HR 5.11, 95 % CI 2.16–12.09, p &lt; 0.001 for OS), likely indicating selection bias for high-risk patients.</div></div><div><h3>Conclusions</h3><div>This study represents the largest European series with a homogeneous treatment approach and long-term follow-up. MC emerge as a distinct high-risk entity, with outcomes akin to angiosarcomas. While surgery remains the cornerstone of treatment, our data challenge the current paradigm regarding adjuvant chemotherapy, highlighting the need for new strategies, particularly for high-risk subtypes.</div></div>","PeriodicalId":11522,"journal":{"name":"Ejso","volume":"51 10","pages":"Article 110265"},"PeriodicalIF":3.5,"publicationDate":"2025-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144605424","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}