Conference Proceedings. 2nd International IEEE EMBS Conference on Neural Engineering, 2005.最新文献_第7页

Cerebral Hemodynamics Assessed by means of Transcranial Doppler and Near - Infrared Spectroscopy in Healthy Smokers and non-Smokers 用经颅多普勒和近红外光谱评价健康吸烟者和非吸烟者的脑血流动力学

Conference Proceedings. 2nd International IEEE EMBS Conference on Neural Engineering, 2005. Pub Date : 2005-03-16 DOI: 10.1109/CNE.2005.1419540

F. Molinari, W. Liboni, G. Grippi, E. Negri

{"title":"Cerebral Hemodynamics Assessed by means of Transcranial Doppler and Near - Infrared Spectroscopy in Healthy Smokers and non-Smokers","authors":"F. Molinari, W. Liboni, G. Grippi, E. Negri","doi":"10.1109/CNE.2005.1419540","DOIUrl":"https://doi.org/10.1109/CNE.2005.1419540","url":null,"abstract":"The assessment of cerebral vasomotor reactivity (VMR) is a valuable tool for the early detection of risk condition in healthy subjects and for the non-invasive bedside evaluation of patients. Typically, cerebral hemodynamics assessment is performed in correspondence of CO2 reactivity. We studied the VMR of a population of young healthy non-smokers (n=10, age 27 plusmn 4.1) and healthy smokers (n=4, age 28 plusmn 4.5) using a joint approach based on transcranial Doppler ultrasonography and near-infrared spectroscopy, to monitor cerebral blood flow velocity (CBFV) and concentrations of oxygenated (O2Hb) and reduced (CO2Hb) haemoglobin. VMR was induced by means of voluntary breath-holding (BH). We quantified VMR using the breath-holding index (BHI). Smokers BH duration was significantly lower than that of non-smokers (p < 10-4; their BHI did not significantly differ from that of non-smokers in terms of CBFV, but differed in terms of O2Hb and CO2Hb concentrations changes. Specifically, with respect to non-smokers, smokers presented a delayed VMR that took place only around 60% of the apnoea phase. This delayed response could reveal an impaired autoregulatory mechanism and could be a risk condition when the subjects need to compensate an abrupt change in the cerebral blood flow","PeriodicalId":113815,"journal":{"name":"Conference Proceedings. 2nd International IEEE EMBS Conference on Neural Engineering, 2005.","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2005-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127719366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Cortical recording with silicon microelectrodes: model-based analysis of contact dimension and encapsulation changes on recorded waveforms 用硅微电极进行皮层记录:基于模型的接触尺寸分析和记录波形上的封装变化

Conference Proceedings. 2nd International IEEE EMBS Conference on Neural Engineering, 2005. Pub Date : 2005-03-16 DOI: 10.1109/CNE.2005.1419575

M. Moffitt, C. McIntyre

{"title":"Cortical recording with silicon microelectrodes: model-based analysis of contact dimension and encapsulation changes on recorded waveforms","authors":"M. Moffitt, C. McIntyre","doi":"10.1109/CNE.2005.1419575","DOIUrl":"https://doi.org/10.1109/CNE.2005.1419575","url":null,"abstract":"Brain machine interfaces represent an emerging area of neurotechnology with both basic science and clinical applications. We developed a model of intracortical microelectrode recording to address the role of contact dimensions, tissue encapsulation, and neuron position on the time course and amplitude of the voltage records. We used a multi-compartment cable model of a 3D reconstruction of a layer V cortical pyramidal neuron to determine transmembrane currents generated during action potential signaling. We coupled the neuron model to finite element models (FEM) of microelectrodes in a cortical tissue medium. The neuronal currents were applied to the FEM and the voltage record at the contact was determined as a function of time. Our results show that the recorded waveform is relatively independent of typical contact sizes (<1000 mum2), but local inhomogeneities in the tissue medium can substantially enhance or suppress signal amplitude. Extensions of these analyses will enable development of silicon-substrate electrodes with optimized contact shape and distribution to achieve specific recording objectives","PeriodicalId":113815,"journal":{"name":"Conference Proceedings. 2nd International IEEE EMBS Conference on Neural Engineering, 2005.","volume":"26 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2005-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125922105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

High Frequency Stimulation Suppresses Compound Action Potentials In Vitro 高频刺激抑制体外复合动作电位

Conference Proceedings. 2nd International IEEE EMBS Conference on Neural Engineering, 2005. Pub Date : 2005-03-16 DOI: 10.1109/CNE.2005.1419555

A. Jensen, D. Durand

{"title":"High Frequency Stimulation Suppresses Compound Action Potentials In Vitro","authors":"A. Jensen, D. Durand","doi":"10.1109/CNE.2005.1419555","DOIUrl":"https://doi.org/10.1109/CNE.2005.1419555","url":null,"abstract":"Deep brain stimulation (DBS), also known as high frequency stimulation (HFS), is a promising method for the therapeutic control of epilepsy; although, the way DBS affects neural elements close to the stimulating electrode remains an important question. Sinusoidal HFS (50 Hz) suppresses synaptic and non-synaptic cellular neural activity in several in vitro epilepsy models. Although, the effects of HFS on axonal conduction are not known. In the present study, we tested the hypothesis that HFS suppresses local axonal conduction in vitro. HFS was locally applied to either the CA1 pyramidale cell layer or the alvear axon field of rat hippocampal slices. Complete suppression was indicated by a 100% reduction in amplitude of the field potential for the duration of the HFS. The results show that sinusoidal HFS suppresses the alvear compound action potential (CAP) as well as the CA1 antidromic evoked potential (AEP). Suppression was dependent on HFS amplitude, while HFS frequency was found not to be statistically significant. HFS applied to the alveus was more effective in suppressing the CAP than HFS applied to the CA1 pyramidale cell layer. These data suggest that HFS can block not only cellular neural firing but also activity in the axons of these cells or axons of passage","PeriodicalId":113815,"journal":{"name":"Conference Proceedings. 2nd International IEEE EMBS Conference on Neural Engineering, 2005.","volume":"216 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2005-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124270074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

MEG Adaptive Noise Suppression using Fast LMS 基于快速LMS的MEG自适应噪声抑制

Conference Proceedings. 2nd International IEEE EMBS Conference on Neural Engineering, 2005. Pub Date : 2005-03-16 DOI: 10.1109/CNE.2005.1419543

N. Ahmar, J. Simon

引用次数: 18

A Wavelet(MZ-DWT) Based Action Potential Detector at Low Signal-to-Noise Ratios 基于小波(MZ-DWT)的低信噪比动作电位检测器

Conference Proceedings. 2nd International IEEE EMBS Conference on Neural Engineering, 2005. Pub Date : 2005-03-16 DOI: 10.1109/CNE.2005.1419617

Dohoon Kim, J. Choi, Taejeong Kim

引用次数: 1

Encoding of Tactile Responses in the Periphery of the Somatosensory System 体感系统外围触觉反应的编码

Conference Proceedings. 2nd International IEEE EMBS Conference on Neural Engineering, 2005. Pub Date : 2005-03-16 DOI: 10.1109/CNE.2005.1419558

S. Leiser, K. Moxon

{"title":"Encoding of Tactile Responses in the Periphery of the Somatosensory System","authors":"S. Leiser, K. Moxon","doi":"10.1109/CNE.2005.1419558","DOIUrl":"https://doi.org/10.1109/CNE.2005.1419558","url":null,"abstract":"Biomimetics, or neuromimetics in particular, have held out the promise that by studying the nervous system we could discern optimal design strategies and parameters to develop better artificial devices. However, when studying natural systems it has proved difficult to abstract useful design strategies. One reason for this difficulty is the poor techniques for studying neural systems during natural behaviors. We developed a novel technique for studying cells in the trigeminal ganglion whose nerve terminals lie in the follicles surrounding the whiskers on the rats face and transduce tactile stimulation to electrical impulses for subsequent processing by the central nervous system. The goals of this work were to 1) determine if the passive response properties of these cells are used by the animal during natural exploration and 2) evaluate how these cells encode complex stimuli. We developed a novel method for chronically recording from these peripheral nerve cells and determined that 1) the passive response properties are used by these primary cells to encode sensory information during natural exploration and 2) while each cell has a narrow range of parameters that it responds to, the rat employs complex behavioral movements of the whiskers and head to optimize the probability of exciting these cells. As a population then, these cells convey complex features of their environment and the CNS uses precise spike timing to decode the information","PeriodicalId":113815,"journal":{"name":"Conference Proceedings. 2nd International IEEE EMBS Conference on Neural Engineering, 2005.","volume":"378 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2005-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122478510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Optimal Input Selection for MISO Systems Identification: Applications to BMIs MISO系统识别的最优输入选择:在bmi中的应用

Conference Proceedings. 2nd International IEEE EMBS Conference on Neural Engineering, 2005. Pub Date : 2005-03-16 DOI: 10.1109/CNE.2005.1419581

E. Perreault, D. Westwick, E. Pohlmeyer, S. Solla, L. Miller

{"title":"Optimal Input Selection for MISO Systems Identification: Applications to BMIs","authors":"E. Perreault, D. Westwick, E. Pohlmeyer, S. Solla, L. Miller","doi":"10.1109/CNE.2005.1419581","DOIUrl":"https://doi.org/10.1109/CNE.2005.1419581","url":null,"abstract":"We have developed an algorithm for selecting an optimal set of inputs for use in linear multiple-input, single-output system identification processes. The algorithm provides a decomposition of the system output such that each component is uniquely attributable to a specific input This reduces the complexity of the estimation problem by optimally selecting inputs according to the uniqueness of their output contribution and is useful in when subsets of the inputs are highly correlated or do not contribute significantly to the system output. The algorithm was evaluated on experimental data consisting of up to 40 simultaneously recorded motor cortical signals and peripheral electromyograms (EMGs) from four upper limb muscles in a freely moving primate. It was used to select the optimal motor cortical signals for predicting each of the EMGs and significantly reduced the number of inputs needed to generate accurate EMG predictions. For example, although physiological recordings from up to 40 different neuronal signals were available, the input selection algorithm reduced this 10 neuronal signals that made significant contributions to the recorded EMGs","PeriodicalId":113815,"journal":{"name":"Conference Proceedings. 2nd International IEEE EMBS Conference on Neural Engineering, 2005.","volume":"34 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2005-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131467820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 5

An investigation of inner light during Zen meditation using alpha-suppressed EEG and VEP 利用抑制脑电图和VEP研究禅宗冥想时的内在光

Conference Proceedings. 2nd International IEEE EMBS Conference on Neural Engineering, 2005. Pub Date : 2005-03-16 DOI: 10.1109/CNE.2005.1419710

Kang-Ming Chang, Chuan-Yi Liu, Pei-Chen Lo

引用次数: 3

Neural Network Controller for an Upper Extremity Neuroprosthesis 上肢神经假体的神经网络控制器

Conference Proceedings. 2nd International IEEE EMBS Conference on Neural Engineering, 2005. Pub Date : 2005-03-16 DOI: 10.1109/CNE.2005.1419641

J. G. Hincapie, D. Blana, E. Chadwick, R. Kirsch

{"title":"Neural Network Controller for an Upper Extremity Neuroprosthesis","authors":"J. G. Hincapie, D. Blana, E. Chadwick, R. Kirsch","doi":"10.1109/CNE.2005.1419641","DOIUrl":"https://doi.org/10.1109/CNE.2005.1419641","url":null,"abstract":"The long term goal of this project is to develop a controller for an upper extremity neuroprosthesis targeted for people with C5/C6 spinal cord injury (SCI). The challenge is to determine how to simultaneously stimulate different paralyzed muscles based on the EMG activity of muscles under retained voluntary control. The proposed controller extracts information from the recorded EMG signals and processes this information to generate the appropriate stimulation levels to activate the paralyzed muscles. The goal of this project was to design and evaluate this controller using a dynamic, three-dimensional musculoskeletal model of the arm. Different arm movements were recorded from able bodied subjects and these kinematics served as input to the model. The model was modified to reflect C5/C6 SCI, and inverse simulations were run to provide muscle activation patterns corresponding to the movements recorded. A set of \"voluntary\" and \"paralyzed\" muscles was selected for the controller based on each muscle's relevance as suggested by the simulations. Activation patterns were then used to train a dynamic neural network that predicts \"paralyzed\" muscle activations from \"voluntary\" muscle activations. The neural network controller was able to predict the activation level of three paralyzed muscles with less than 2% average prediction error, using four input muscles as inputs","PeriodicalId":113815,"journal":{"name":"Conference Proceedings. 2nd International IEEE EMBS Conference on Neural Engineering, 2005.","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2005-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129580151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Spontaneous bursts are better indicators of tetanus-induced plasticity than responses to probe stimuli 自发爆发是破伤风诱发的可塑性的较好指标，而不是对探针刺激的反应

Conference Proceedings. 2nd International IEEE EMBS Conference on Neural Engineering, 2005. Pub Date : 2005-03-16 DOI: 10.1109/CNE.2005.1419652

Radhika Madhavan, Zenas C. Chao, Steve M. Potter

引用次数: 18