Conference Proceedings. 2nd International IEEE EMBS Conference on Neural Engineering, 2005.最新文献_第5页

Deep brain stimulation of the subthalamic nucleus: model-based analysis of the effects of electrode capacitance on the volume of activation 丘脑底核的深部脑刺激:电极电容对激活体积影响的基于模型的分析

Conference Proceedings. 2nd International IEEE EMBS Conference on Neural Engineering, 2005. Pub Date : 2005-03-16 DOI: 10.1109/CNE.2005.1419589

C. Butson, C.C. Mclntyre

{"title":"Deep brain stimulation of the subthalamic nucleus: model-based analysis of the effects of electrode capacitance on the volume of activation","authors":"C. Butson, C.C. Mclntyre","doi":"10.1109/CNE.2005.1419589","DOIUrl":"https://doi.org/10.1109/CNE.2005.1419589","url":null,"abstract":"Deep brain stimulation (DBS) has rapidly emerged as an effective clinical treatment for movement disorders. However, our understanding of the neural effects of DBS is limited, and significant opportunities exist to optimize electrode design to enhance therapeutic effectiveness. To address these issues, we have developed computational tools to predict the neural response to stimulation. For decades the electrostatic approximation has been applied in neural stimulation modeling, treating the electrode as a perfect current source and the neural tissue as a purely conductive medium. However, clinical DBS electrodes are voltage controlled, utilize an asymmetrical biphasic stimulus waveform, and are surrounded by a 3D anisotropic, inhomogeneous tissue medium. To more accurately model DBS in the human, we have developed finite element models (FEM) of the electrode and tissue medium that incorporate a Fourier FEM solver to determine the potential distribution in the tissue in time and space simultaneously. The field data is then coupled to multi-compartment neuron models to predict neural activation. Our results show that electrostatic models overestimate the volume of activation (VOA) by -30% compared to voltage-controlled stimulation for typical therapeutic stimulation parameter settings. The error is directly related to the electrode capacitance and the stimulation pulse width. These results illustrate the need for detailed models of neural stimulation to accurately predict the effects of DBS","PeriodicalId":113815,"journal":{"name":"Conference Proceedings. 2nd International IEEE EMBS Conference on Neural Engineering, 2005.","volume":"113 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2005-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126213734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

A Fully-Automated Neural Spike Sorting Based on Projection Pursuit and Gaussian Mixture Model 基于投影寻踪和高斯混合模型的全自动神经脉冲排序

Conference Proceedings. 2nd International IEEE EMBS Conference on Neural Engineering, 2005. Pub Date : 2005-03-16 DOI: 10.1109/CNE.2005.1419576

Kyung Hwan Kim

引用次数: 2

Design of Two-Dimensional Grid Electrodes Considering Spatial Characteristics of SEMG Signal 考虑表面肌电信号空间特征的二维网格电极设计

Conference Proceedings. 2nd International IEEE EMBS Conference on Neural Engineering, 2005. Pub Date : 2005-03-16 DOI: 10.1109/CNE.2005.1419616

M.M. Rahman, M. Ferdjallah, G. Harris

{"title":"Design of Two-Dimensional Grid Electrodes Considering Spatial Characteristics of SEMG Signal","authors":"M.M. Rahman, M. Ferdjallah, G. Harris","doi":"10.1109/CNE.2005.1419616","DOIUrl":"https://doi.org/10.1109/CNE.2005.1419616","url":null,"abstract":"Surface grid electrode is a noninvasive technique, which can be utilized for topographic analysis of EMG signals. Grid electrode increases the uptake area and provides a better picture of spatial and temporal characteristics of muscle activity. Determination of clinical parameters such as muscle conduction velocity, location of innervation zone, firing pattern, size and location of motor unit, are some of the challenging applications of multi-electrode array. However, an optimum grid electrode requires detail examination regarding the dimension and inter-electrode distance of the array. In this paper a systematic approach is presented for selecting a grid spacing to reduce spatial aliasing. The characteristics of isotropic layers of subcutaneous fat and skin tissues are incorporated in a computer muscle model in order to analyze their effects on complete potential profile and grid spacing. The variation of spatial cutoff frequency and corresponding inter electrode distance with depth of muscle fiber inside the muscle are simulated in both time and frequency domain for three different levels of accuracy","PeriodicalId":113815,"journal":{"name":"Conference Proceedings. 2nd International IEEE EMBS Conference on Neural Engineering, 2005.","volume":"25 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2005-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129951012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Comparison of EEG Preprocessing Methods using Time Delay Neural Networks 基于时滞神经网络的脑电信号预处理方法比较

Conference Proceedings. 2nd International IEEE EMBS Conference on Neural Engineering, 2005. Pub Date : 2005-03-16 DOI: 10.1109/CNE.2005.1419607

R. Rao, R. Derakhshani

引用次数: 26

An Integrated System for Multichannel Neuronal Recording with Spike / LFP Separation and Digital Output 一种具有尖峰/ LFP分离和数字输出的多通道神经元记录集成系统

Conference Proceedings. 2nd International IEEE EMBS Conference on Neural Engineering, 2005. Pub Date : 2005-03-16 DOI: 10.1109/CNE.2005.1419637

Y. Perelman, Ran Ginosar

引用次数: 11

A Boosting Approach to P300 Detection with Application to Brain-Computer Interfaces 基于脑机接口的P300增强检测方法

Conference Proceedings. 2nd International IEEE EMBS Conference on Neural Engineering, 2005. Pub Date : 2005-03-16 DOI: 10.1109/CNE.2005.1419562

U. Hoffmann, G. garcia, J. Vesin, K. Diserens, T. Ebrahimi

引用次数: 100

Synchronous stereo-video and biosignal recording - a basic setup for Human-Computer-Interface applications 同步立体视频和生物信号记录-人机界面应用程序的基本设置

Conference Proceedings. 2nd International IEEE EMBS Conference on Neural Engineering, 2005. Pub Date : 2005-03-16 DOI: 10.1109/CNE.2005.1419669

O. Burmeister, M. Litza, M. Nitschke, U. Hofmann

引用次数: 7

Dynamic Simulation and Testing of the Electrode-Electrolyte Interface of 3-D Stimulating Microelectrodes 三维刺激微电极电极-电解质界面的动态仿真与测试

Conference Proceedings. 2nd International IEEE EMBS Conference on Neural Engineering, 2005. Pub Date : 2005-03-16 DOI: 10.1109/CNE.2005.1419584

A. Hung, D. Zhou, R. Greenberg, J. Judy

引用次数: 5

Continuous Quantitative Motor Evoked Potentials for Spinal Cord Injury Detection 连续定量运动诱发电位检测脊髓损伤

Conference Proceedings. 2nd International IEEE EMBS Conference on Neural Engineering, 2005. Pub Date : 2005-03-16 DOI: 10.1109/CNE.2005.1419651

Hongxuan Zhang, Y. Oweis, H. Mozaffari-Naeini, S. Venkatesha, N. Thakor, A. Natarajan

引用次数: 3

Bioelectronic Artificial Nose Using Four-Channel Moth Antenna Biopotential Recordings 利用四通道飞蛾天线生物电位记录的生物电子学人工鼻子

Conference Proceedings. 2nd International IEEE EMBS Conference on Neural Engineering, 2005. Pub Date : 2005-03-16 DOI: 10.1109/CNE.2005.1419620

A. Myrick, T. Baker, K. Park, J. Hetling

{"title":"Bioelectronic Artificial Nose Using Four-Channel Moth Antenna Biopotential Recordings","authors":"A. Myrick, T. Baker, K. Park, J. Hetling","doi":"10.1109/CNE.2005.1419620","DOIUrl":"https://doi.org/10.1109/CNE.2005.1419620","url":null,"abstract":"The use of insect antennae as an odor sensor array was evaluated as a means to advance the current capabilities of \" artificial nose\" technology. A given species is highly sensitive to odors of survival interest (e.g. species-specific pheromones), but also to a broad range of other natural and anthropogenic compounds. The sensitivity of the antennae to some odors extends to the parts per billion range. In contrast, the best current artificial nose technology is able to detect compounds in the parts per million range. Here, a system designed to utilize four antenna biopotential signals suitable for field use and a computational analysis strategy which allows discrimination between specific odors, and between odor and background or unknown compounds, with high fidelity and in real time, is described. The automated analysis measures three parameters per odor response. Following a training period, a K nearest-neighbor (KNN) approach is used to classify an unknown odor, assuming equal prior probabilities. The algorithm can also declare an odor as \"unknown\". System responses to single filaments in an odor plume can be analyzed and classified in less than one second","PeriodicalId":113815,"journal":{"name":"Conference Proceedings. 2nd International IEEE EMBS Conference on Neural Engineering, 2005.","volume":"11 5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2005-03-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132874624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 6