American Journal of Chemistry and Pharmacy最新文献_第2页

Covid Infection and Variables Affecting its Severity Among Pregnant Women in Dubai 迪拜孕妇感染新冠病毒及其严重程度的影响因素

American Journal of Chemistry and Pharmacy Pub Date : 2023-04-30 DOI: 10.54536/ajcp.v2i1.1397

Kefah El Debek, Hamdan Bin Muhammad

{"title":"Covid Infection and Variables Affecting its Severity Among Pregnant Women in Dubai","authors":"Kefah El Debek, Hamdan Bin Muhammad","doi":"10.54536/ajcp.v2i1.1397","DOIUrl":"https://doi.org/10.54536/ajcp.v2i1.1397","url":null,"abstract":"The acute respiratory syndrome has produced an unprecedented global disaster since December 2019 known as coronavirus 2 (SARS-CoV-2). Pregnant women are a particular group that needs special care during crises and infectious illnesses. Compared to uninfected women, this cross-sectional study was based on pregnant women infected with COVID-19. The data was collected from DHA Latifa Hospital, Medical records. The research committee approved the study in DHA. The study was based on 326 patients aged 20-42 years, of which COVID-infected pregnant women were 199 and 118 were uninfected. Most patients were from the UAE, with a mean age of 31.63+ 6.36 and an average BMI of 28.96±1.16 kg/m2 of COVID-infected pregnant women. While the mean age of 31.33+ 6.23 and an average BMI of 27.06±11.05 kg/m2 of uninfected pregnant women. Hemoglobin (HB), White Blood cells (WBCs), and C-Reactive Protein(CRP) showed significantly different when compared to COVID-infected and uninfected pregnant women. Significant results showed in Comorbid diseases compared with COVID-infected and uninfected pregnant women, but a high frequency was observed in uninfected women. The results showed insignificance with Comorbid diseases when compared with COVID- infected pregnant women and uninfected pregnant women. A decrease in WBC and CRP was observed in COVID- infected pregnant women","PeriodicalId":113806,"journal":{"name":"American Journal of Chemistry and Pharmacy","volume":"9 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117061437","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Synthesis and Characterization of Alpinia calcarata Loaded Nanoparticles to Control Hyperglycemia calcalata纳米颗粒控制高血糖的合成与表征

American Journal of Chemistry and Pharmacy Pub Date : 2023-03-10 DOI: 10.54536/ajcp.v2i1.1293

B. Wanniarachchi, P. G. U. Chathuranga, P. H. U. W. De Silva, B. Jayawardena

{"title":"Synthesis and Characterization of Alpinia calcarata Loaded Nanoparticles to Control Hyperglycemia","authors":"B. Wanniarachchi, P. G. U. Chathuranga, P. H. U. W. De Silva, B. Jayawardena","doi":"10.54536/ajcp.v2i1.1293","DOIUrl":"https://doi.org/10.54536/ajcp.v2i1.1293","url":null,"abstract":"Bovine Serum Albumin (BSA) nanoparticles loaded with the bioactive compounds of A. calcarata, which is known to exert its antidiabetic activity through the inhibition of pancreatic enzymes, are a good form of an antidiabetic nutraceutical as they have reduced side effects, protection of active compounds from environmental agents, specific delivery to target sites and prolonged shelf-life. The objective of the present study was to synthesize and characterize A. calcarata loaded nanoparticles (ALNP) to be used as a powder form nutraceutical with higher antidiabetic activity. In this study an aqueous A. calcarata extract (4.00 mL) was added to BSA (20 mg/mL, 4.00 mL, pH 9) in the presence of citric acid as the cross-linking agent. The ALNP gave an IC50 value of 147 µg/mL, a glucose (5 mM) uptake percentage of 73.09% at a 0.5 mg/mL concentration, a solubility value of 64%, A. calcarata loading percentage of 6.66% and A. calcarata entrapment efficiency of 87.71%. They had a spherical morphology and uniform size with a particle size of 1030.70 nm, PDI of 0.199 and a zeta potential of 2.57 mV. The UV-Visible absorbance spectra and FT-IR spectra showed that citric acid had caused conformational changes in the protein structure of BSA and that the active compounds were successfully loaded into the synthesized nanoparticles which interacted with the protein matrix via covalent bonds. Therefore, it can be concluded that the synthesized nanoparticles have an antidiabetic effect and the antidiabetic activity of bioactive compounds of the aqueous A. calcarata extract become enhanced when loaded onto the nanocarriers.","PeriodicalId":113806,"journal":{"name":"American Journal of Chemistry and Pharmacy","volume":"32 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125867412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Study on the Therapeutic Effect of 5-Azacytidine to Attenuate the Ramifying Repercussions of Ischemia Reperfusion Injury on Mitochondrial Molecular Machinery 5-氮杂胞苷减轻缺血再灌注损伤对线粒体分子机制影响的研究

American Journal of Chemistry and Pharmacy Pub Date : 2023-02-05 DOI: 10.54536/ajcp.v2i1.1169

Vasisht Yegneshwaran, Priyanka N. Prem, S. Boovarahan, G. Kurian

{"title":"A Study on the Therapeutic Effect of 5-Azacytidine to Attenuate the Ramifying Repercussions of Ischemia Reperfusion Injury on Mitochondrial Molecular Machinery","authors":"Vasisht Yegneshwaran, Priyanka N. Prem, S. Boovarahan, G. Kurian","doi":"10.54536/ajcp.v2i1.1169","DOIUrl":"https://doi.org/10.54536/ajcp.v2i1.1169","url":null,"abstract":"5-Azacytidine is a hypomethylating agent that has for long been used in cancer therapy due to its ability to inhibit the protein DNA methyltransferase responsible for hyper-methylating DNA strands. Recently, studies involving in vitro, ex vivo, and in vivo experiments have assessed the cardioprotective effects of 5-Azacytidine during myocardial ischemia-reperfusion injury (IRI). However, the effect of this compound in restoring the damage induced to mitochondrial molecular machinery during IRI has not yet been explored. Understanding this would help us analyze the ways through which mito-targeted therapeutics can be used. The purpose of this study is to investigate the therapeutic impact of 5-Azacytidine, as DNA methylation is a very common epigenetic modification observed during IRI. Furthermore, the protective effect of the compound in alleviating the damage induced to mitochondria during IRI can be identified, as DNA methylation can leave a direct impact on the mitochondrial genes as well. An isolated mitochondria model will be used to determine the effects of 5-Azacydine on mitochondrial molecular machinery as the capacity to generate DNA, RNA, and proteins are preserved in isolated mitochondria. In this study, we focus on the mechanisms of mitochondrial replication, and translation to understand the effect of 5-Azacytidine on the IRI affected mitochondrial system. Mitochondrial dysfunction is also another key turn of events that happens during IRI. The role of 5-Azacyidine in preserving the functionality is also being assessed in our research. The findings of these experiments would help us determine the plasticity the compound imparts on mitochondrial molecular mechanism’s integrity and function post-induced IRI.","PeriodicalId":113806,"journal":{"name":"American Journal of Chemistry and Pharmacy","volume":"74 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115692833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Relationship Between the Type of Dimensions (3D, 2D) and Mental Interaction (High, Low) in the Augmented Reality Environment and its Effects on Learning 增强现实环境中维度类型(3D、2D)与心理互动(高、低)的关系及其对学习的影响

American Journal of Chemistry and Pharmacy Pub Date : 2023-01-15 DOI: 10.54536/ajcp.v2i1.1075

S. Safaan

{"title":"The Relationship Between the Type of Dimensions (3D, 2D) and Mental Interaction (High, Low) in the Augmented Reality Environment and its Effects on Learning","authors":"S. Safaan","doi":"10.54536/ajcp.v2i1.1075","DOIUrl":"https://doi.org/10.54536/ajcp.v2i1.1075","url":null,"abstract":"The research aims to reveal the relationship between the type of dimensions (3D, 2D) and the type of mental interaction (high and low) and its impact on students’ knowledge of the types of wireless networks and their components in the course “Wireless Communications and Mobile Security” based on their satisfaction with this learning, and their academic achievement. The research sample is 144 students in the second year, fourth level of the cybersecurity diploma, and they were divided into four experimental groups. The first experimental group studies with books augmented with three-dimensional models with high mental interaction, and the second experimental group studies with books augmented with three-dimensional models with low mental interaction. The third experimental group is taught with books augmented with two-dimensional models with high mental interaction, and finally, the fourth experimental group is taught with virtual books with two-dimensional models with low mental interaction. The research results that there is an interaction between the type of dimensions in augmented reality books and the mental interaction (high, low) in identifying the types of wireless networks and their components, where the high mental interaction groups excelled, regardless of the type of dimensions (3D, 2D) in the achievement test, and there was clear satisfaction for the students of the groups that study with 3D models compared to the 2D groups.","PeriodicalId":113806,"journal":{"name":"American Journal of Chemistry and Pharmacy","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127358082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Computer Forensics Education: The Applications of Forensic Tools in Modern Education System 计算机取证教育:取证工具在现代教育系统中的应用

American Journal of Chemistry and Pharmacy Pub Date : 2022-12-29 DOI: 10.54536/ajcp.v1i2.1077

S. Safaan

{"title":"Computer Forensics Education: The Applications of Forensic Tools in Modern Education System","authors":"S. Safaan","doi":"10.54536/ajcp.v1i2.1077","DOIUrl":"https://doi.org/10.54536/ajcp.v1i2.1077","url":null,"abstract":"Cybercrime and computer-related incidents are becoming more prevalent and common, resulting in billions of dollars in damages. To address these crimes and scams, there is an urgent need to build digital forensics training programme, that will equip relevant professionals to investigate computer crime and events efficiently. There is presently no standard that governs the development of an academic program’s digital forensics curriculum. This study extensively investigates prior work on curriculum design in digital forensics as well as existing computer forensics course offered at the first is the Community College in Buraidah, and the second is the Community College in Unaizah namely, “Cyber Security Diploma” The Cyber Security Diploma is offered in both colleges, the Community College in Buraidah and Unaizah, and the diploma is at the third level of the course “Computer Forensic Analysis,” which is the focus of the research topic. Interviews were conducted with both digital forensic trainers and practitioners, and the findings were examined in order to identify and assess the skills and knowledge required by the industry and law enforcement agencies for their digital forensic examiners. Hands-on training may be delivered by constructing and managing a student laboratory specifically designed for digital forensic examination instruction. A laboratory can be outfitted with a wide range of software solutions, ranging from commercial investigation suites to free command line tools. Similarly, the forensic workstations that execute the software might be supplied by the vendor as stand-alone devices or assembled from separate components in-house. Building and administering a student lab successfully can be a daunting task, but it can also be done on a little budget as long as the focus stays on student achievement.","PeriodicalId":113806,"journal":{"name":"American Journal of Chemistry and Pharmacy","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-12-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125983053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Oral Acyclovir Induced Acute Kidney Injury 口服阿昔洛韦致急性肾损伤

American Journal of Chemistry and Pharmacy Pub Date : 2022-11-01 DOI: 10.54536/ajcp.v1i2.829

Sadawey Yasser, Abdulhameed Yasameen

引用次数: 0

Empagliflozin-Induced Acute Pancreatitis and Euglycemic Diabetic Ketoacidosis in Type 2 Diabetes Mellitus 恩格列净诱导的2型糖尿病急性胰腺炎和糖尿病酮症酸中毒

American Journal of Chemistry and Pharmacy Pub Date : 2022-10-23 DOI: 10.54536/ajcp.v1i2.747

Sadawey Yasser, Metwally Hesham

引用次数: 0

Dietary Risks Assessment of Antibiotic Residues and Microbial Safety of Local Honey in Adamawa State 阿达马瓦州当地蜂蜜抗生素残留和微生物安全的膳食风险评估

American Journal of Chemistry and Pharmacy Pub Date : 2022-09-12 DOI: 10.54536/ajcp.v1i1.492

F.B Dowell, O. Maitera, M. Daniel, M. Micah

{"title":"Dietary Risks Assessment of Antibiotic Residues and Microbial Safety of Local Honey in Adamawa State","authors":"F.B Dowell, O. Maitera, M. Daniel, M. Micah","doi":"10.54536/ajcp.v1i1.492","DOIUrl":"https://doi.org/10.54536/ajcp.v1i1.492","url":null,"abstract":"This study investigated the microbial safety and dietary risk assessments of antibiotic residues in honey. The determination of antibiotic residues in this study were carried out using HPLC (LC 1200 series Agilent Tech). The results of the microbial analysis of the honey samples showed that, some of the honey samples were contaminated with micro-organisms. The antibiotics with highest mean concentration in the study were chloramphenicol (6.468±0.03 µg/kg) and sulfonamide (5.553±0.04 µg/kg) from sample HS1 and HG2 respectively. Estimated daily intake (EDIs) of detected antibiotic residues which were compared with the recommended acceptable daily intake (ADIs) for each antibiotic allowed in food. Chloramphenicol was observed to possess the highest risk for adults and children (1.08E-04 µg/kg/bw) and (4.31E-04 µg/kg/bw) respectively in sample HS1. All the EDIs evaluated for antibiotic residues falls below acceptable daily intake (ADI). The target hazard quotient (THQ) and health index (HI) for antibiotic residues in all the samples were < 1, this suggested no risks associated with the level of antibiotic residues risks thus having less danger to human health through its consumption.","PeriodicalId":113806,"journal":{"name":"American Journal of Chemistry and Pharmacy","volume":"2016 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125730563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Magnitude and Associated Factors for Sexually Transmitted Infections Among Hawassa Industrial Park Workers, Southern Ethiopia 埃塞俄比亚南部哈瓦萨工业园工人性传播感染的程度及相关因素

American Journal of Chemistry and Pharmacy Pub Date : 2022-09-04 DOI: 10.54536/ajcp.v1i1.431

Solomon Tesfaye Doelaso

{"title":"Magnitude and Associated Factors for Sexually Transmitted Infections Among Hawassa Industrial Park Workers, Southern Ethiopia","authors":"Solomon Tesfaye Doelaso","doi":"10.54536/ajcp.v1i1.431","DOIUrl":"https://doi.org/10.54536/ajcp.v1i1.431","url":null,"abstract":"Sexually Transmitted Infections (STI) are a group of infectious diseases spread through unprotected sexual intercourses, resulting in curable and incurable diseases. The syndrome is a variety of clinical signs and symptoms caused by pathogens that can be acquired and transmitted through sexual activity. Around the world estimated about 376 million people become infected each year with one of four common curable STIs where about 86 million new cases of curable STIs occurred in the African region. The objective of this study to assess the magnitude and associated factors for Sexually transmitted infections in 2020 among Hawassa industrial park workers, Southern Ethiopia. The multistage sampling technique was used to select a total of 663 study participants. The data were entered into the Epi-Data version 4.4 and analyzed by SPSS version 21. Both bivariate and multivariable logistic regression analyses were employ P-values of <0.05 and AOR with 95%CI was used to determine the presence of association between covariates and dependent variable.. The Self-reported STI magnitude in the last 12 months was 18.7% (18.54-18.91) among the Hawassa industry park workers. Hometown residence [AOR=2.29; 95%CI: 1.34-3.92], drinking alcohol (AOR=3.26; 95%CI: 1.74-6.09), view/read pornography (AOR=4.38; 95%CI: 2.67-7.18) and poor knowledge (AOR=2.69; 95%CI: 1.65-4.420 were significantly associated with the magnitude of STIs. The Self-reported magnitude of STIs among Hawassa Industrial Park was found to be high.","PeriodicalId":113806,"journal":{"name":"American Journal of Chemistry and Pharmacy","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128965050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cause of Land Degradation and Rehabilitation Practices in Case of Amba Sidist Western Ethiopia 埃塞俄比亚西部Amba Sidist土地退化的原因和恢复措施

American Journal of Chemistry and Pharmacy Pub Date : 2022-08-23 DOI: 10.54536/ajcp.v1i1.419

Dessalew Shitu

{"title":"Cause of Land Degradation and Rehabilitation Practices in Case of Amba Sidist Western Ethiopia","authors":"Dessalew Shitu","doi":"10.54536/ajcp.v1i1.419","DOIUrl":"https://doi.org/10.54536/ajcp.v1i1.419","url":null,"abstract":"In Ethiopia, land degradation has become a serious problem affecting all spheres of social, economic and political life of the population. It is one of the major challenges to agricultural development and food security of the country. In order to solve the problem of land degradation, a lot of efforts have been made since 1970s. However, at the end the intervention couldn’t be sustainable and able to bring the intended impact. Thus, identification of challenges in relation to land rehabilitation practices is of paramount importance. The study was undertaken in Amba 6 kebele. In order to achieve the objective of the study, both primary and secondary data were generated by employing qualitative and quantitative data. Stratified sampling technique was used to select 76 household heads were selected from on Amba 6 by using stratified random sampling as it is believed that the households are similar with respect to the characteristics that influence the research output. The process of analysis of the study was carried out using qualitative description and quantitative analysis. The quantitative data was analyzed using frequency, percentage and mean when appropriate. The qualitative data was discussed to substantiate the study. The findings of the study indicated that decrease in productivity of farm land, involvement in off-farm activities, increase in size of human population, lack of full cooperation of family members to involve in land rehabilitation practices, low assistance gained from neighbor-hoods, less access to extension service and inadequate attention from woreda Agriculture and Rural Development office are the major challenges encountering the implementation of land rehabilitation practices in effective way.","PeriodicalId":113806,"journal":{"name":"American Journal of Chemistry and Pharmacy","volume":"104 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128029052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3