Empagliflozin-Induced Acute Pancreatitis and Euglycemic Diabetic Ketoacidosis in Type 2 Diabetes Mellitus

Sadawey Yasser, Metwally Hesham
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Abstract

Acute pancreatitis and euglycemic DKA, EDKA, are uncommon but potentially fatal complications in diabetic patients on sodium-glucose cotransporter 2 inhibitors (SGLT2). This case report presents the exceptional occurrence of a 49-year-old; male patient diagnosed with empagliflozin-induced EDKA coupled with T2DM as a precursor to acute pancreatitis. Euglycemic DKA may be produced after administering just one dose of SGLT2. On discharge, empagliflozin was managed to stop. Since the initial administration of SGLT2, this diagnosis should be considered a potential consequence. Appropriate medical treatment is made possible by diagnosing and treating this life-threatening condition promptly.
恩格列净诱导的2型糖尿病急性胰腺炎和糖尿病酮症酸中毒
在使用钠-葡萄糖共转运蛋白2抑制剂(SGLT2)的糖尿病患者中,急性胰腺炎和血糖性DKA (EDKA)并不常见,但可能是致命的并发症。本病例报告提出了一个异常发生的49岁;诊断为恩格列净诱导的EDKA合并T2DM为急性胰腺炎前兆的男性患者。只需给药一剂SGLT2即可产生促血糖DKA。出院时,恩帕列净被设法停用。由于最初使用SGLT2,该诊断应被视为潜在的后果。通过及时诊断和治疗这种危及生命的疾病,可以进行适当的医疗。
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