Digestive Diseases and Sciences最新文献

{"title":"Homemade Microbrew: Auto-brewery Syndrome in a Patient with Crohn's Disease.","authors":"Alexandra C Leto, Michael Shen, Faten N Aberra","doi":"10.1007/s10620-026-10175-6","DOIUrl":"10.1007/s10620-026-10175-6","url":null,"abstract":"","PeriodicalId":11378,"journal":{"name":"Digestive Diseases and Sciences","volume":" ","pages":"6119-6122"},"PeriodicalIF":2.8,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148789460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnostic Accuracy of Optical Endoscopic Evaluation and EUS for Differentiating T1a and T1b Barrett's Adenocarcinoma: A Systematic Review and Meta-Analysis.","authors":"Rinrada Worapongpaiboon, Suchapa Arayakarnkul, Kasenee Tiankanon, Saowanee Ngamruengphong","doi":"10.1007/s10620-026-10113-6","DOIUrl":"10.1007/s10620-026-10113-6","url":null,"abstract":"<p><strong>Background and aims: </strong>Accurate differentiation between T1a and T1b Barrett's adenocarcinoma (BAC) is essential for selecting endoscopic resection (ER) versus surgery. The diagnostic reliability of optical endoscopic evaluation (OEE) and endoscopic ultrasound (EUS) remains inconsistent. We performed a systematic review and meta-analysis to assess their diagnostic performance.</p><p><strong>Methods: </strong>PubMed, Embase, Scopus, and Cochrane were searched through December 2025. Studies evaluating OEE or EUS for differentiating T1a from T1b BAC were included. Pooled sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and accuracy were calculated using random-effects models. Heterogeneity was assessed with I². Hierarchical summary receiver operating characteristic (HSROC) analysis compared modalities. Secondary analyses evaluated Paris morphology and Barrett's segment length (BSL) using diagnostic odds ratios (DORs).</p><p><strong>Results: </strong>Nineteen studies (2,292 patients) were included. OEE showed pooled sensitivity of 55.3% and specificity of 75.1%, with accuracy of 63.1%. EUS demonstrated sensitivity of 66.1%, specificity of 89.3%, and accuracy of 82.8%. HSROC analysis showed no significant difference between modalities (AUC 0.69 vs 0.87; P = 1). Paris 0-I, 0-IIa, lesions with 0-IIc components, and BSL ≥ 3 cm were not associated with T1b invasion. Paris 0-IIb lesions were significantly less likely to harbor T1b disease (DOR 0.17, 95% CI 0.07-0.38).</p><p><strong>Conclusions: </strong>Both OEE and EUS demonstrate modest accuracy for differentiating T1a from T1b BAC. Endoscopic morphology is not a reliable predictor of submucosal invasion, except for flat lesions being less likely T1b. ER remains essential for definitive staging.</p>","PeriodicalId":11378,"journal":{"name":"Digestive Diseases and Sciences","volume":" ","pages":"5496-5510"},"PeriodicalIF":2.8,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148445214","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Epidemiology of Acute Colonic Pseudo-obstruction (Ogilvie Syndrome) Based on Disease-Specific Data.","authors":"Bahar Saberzadeh-Ardestani, Loren Laine","doi":"10.1007/s10620-026-10142-1","DOIUrl":"10.1007/s10620-026-10142-1","url":null,"abstract":"<p><strong>Purpose: </strong>Prior epidemiologic assessment of acute colonic pseudo-obstruction (ACPO) used nonspecific ICD-9 coding preventing precise case identification. Implementation of disease-specific ICD-10-CM code K59.81 (Ogilvie syndrome) in 2020 enables more accurate characterization.</p><p><strong>Methods: </strong>Adults with ICD-10-CM code K59.81 in the 2021-2022 National Inpatient Sample were identified. Patients were classified into four treatment groups: medical management, colonoscopy alone, surgery alone, and combined colonoscopy/surgery. Multivariable regression models assessed associations between treatment group and outcomes.</p><p><strong>Results: </strong>Age/sex adjusted incidences of ACPO hospitalization were 3.99 and 4.03 per 100,000 population in 2021 and 2022. Incidence was higher in males than females (66% of cases were in men) and increased with age in both sexes. Medical management was the predominant treatment (77.9%), followed by colonoscopy alone (13.0%), surgery alone (6.6%), and combined colonoscopy/surgery (2.4%). Complication and mortality rates were 4.9% and 6.8%. In adjusted analyses, compared to medical management, surgery (OR = 11.48; 95% CI 7.45-17.71) and combined colonoscopy/surgery (OR = 10.41; 95% CI 5.49-19.73) had higher complications, surgery alone had higher mortality (OR = 2.51; 95% CI 1.87-3.37), colonoscopy alone trended toward lower mortality (OR = 0.67; 95% CI 0.45-1.00), and all procedural interventions had longer hospital stays.</p><p><strong>Conclusions: </strong>Disease-specific diagnostic coding for ACPO identified a population with pronounced male predominance and higher incidence in the elderly. Colonoscopy was used in 15% of cases and surgery in 9%. While most patients with ACPO require only medical management, colonoscopy was not associated with increased complications and potentially may be associated with reduced mortality. Surgery had the highest complication and mortality rates, likely reflecting greater disease severity in patients requiring operative intervention in addition to the risks of surgery.</p>","PeriodicalId":11378,"journal":{"name":"Digestive Diseases and Sciences","volume":" ","pages":"5683-5690"},"PeriodicalIF":2.8,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148535576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Impact of Fistulizing Disease, Treatment Modalities, and Clinical Activity on Health-Related Quality of Life in Crohn's Disease.","authors":"Haluk Tarik Kani, Yasemin Kaldirim Armutcuoglu, Ilkay Ergenc, Begum Ozsarac, Beyza Nur Sahin, Gamzenur Kaya, Bunyamin Oztemiz, Burak Can Demir, Ozlen Atug, Yesim Ozen Alahdab","doi":"10.1007/s10620-026-10135-0","DOIUrl":"10.1007/s10620-026-10135-0","url":null,"abstract":"<p><strong>Background: </strong>Fistulizing Crohn's disease (CD) is a severe phenotype associated with morbidity and impaired health-related quality of life (HRQoL). However, it remains unclear whether HRQoL impairment is driven by fistula presence or ongoing inflammatory activity. This study aimed to evaluate the association of fistulizing disease, disease activity, and treatment exposure with HRQoL.</p><p><strong>Methods: </strong>This cross-sectional study included consecutive adult patients with CD attending a tertiary inflammatory bowel disease clinic. Patients were classified as having fistulizing or non-fistulizing disease. The primary outcome was HRQoL, assessed using the Inflammatory Bowel Disease Questionnaire (IBDQ) and its four subdomains. Luminal and perianal disease activities were evaluated using the Crohn's Disease Activity Index (CDAI) and Perianal Disease Activity Index (PDAI). Associations were analyzed using t-test or Mann-Whitney U test, Chi-square or Fisher's exact test, and Spearman's rank correlation, as appropriate.</p><p><strong>Results: </strong>A total of 209 patients were included (mean age 38.6 ± 13.1 years; 36.8% female); 106 (50.7%) had fistulizing disease, predominantly perianal. Female sex was associated with lower total IBDQ scores (p < 0.001). CDAI showed a moderate inverse correlation with total IBDQ score (ρ = -0.538, p < 0.001), and PDAI was also negatively correlated with total IBDQ score (ρ = -0.372, p = 0.001). Similar correlations were observed across all IBDQ subdomains. Fistula presence, including perianal fistulas, smoking status, prior surgery, and biologic exposure were not significantly associated with HRQoL.</p><p><strong>Conclusions: </strong>Active luminal and perianal inflammation, rather than fistula presence alone, appears to be the principal determinant of HRQoL in CD.</p>","PeriodicalId":11378,"journal":{"name":"Digestive Diseases and Sciences","volume":" ","pages":"5737-5744"},"PeriodicalIF":2.8,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148600394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Higher Off-Therapy Relapse Risk with Tenofovir Alafenamide than Entecavir in Non-cirrhotic HBeAg-Negative Chronic Hepatitis B: Insights from End-of-Treatment qHBsAg Stratification.","authors":"Yi-Jie Huang, Chung-Hsin Chang, Shou-Wu Lee, Chun-Fang Tung, Szu-Chia Liao, Teng-Yu Lee, Yen-Chun Peng, Jun-Sing Wang","doi":"10.1007/s10620-026-10188-1","DOIUrl":"10.1007/s10620-026-10188-1","url":null,"abstract":"<p><strong>Background and aims: </strong>End-of-treatment (EOT) qHBsAg predicts off-therapy relapse in HBeAg-negative chronic hepatitis B (CHB), but whether its stratifying ability differs between entecavir (ETV) and tenofovir alafenamide (TAF) remains unclear. This study compared 12-month relapse risk across EOT qHBsAg strata after ETV or TAF discontinuation in non-cirrhotic HBeAg-negative CHB patients.</p><p><strong>Methods: </strong>In this retrospective cohort study, non-cirrhotic HBeAg-negative CHB patients discontinuing ETV or TAF were 1:1 propensity score matched. Virological relapse was assessed by Kaplan-Meier analysis and Cox regression; clinical relapse by cumulative incidence functions with Fine-Gray competing risks regression. Hazard ratios and subdistribution hazard ratios (sHRs) were compared across EOT qHBsAg strata (< 2, 2-3, ≥3 log₁₀ IU/mL).</p><p><strong>Results: </strong>A total of 130 patients (65 per group) were analyzed. Among ETV discontinuers, clinical relapse rates increased progressively with higher EOT qHBsAg (0.0%, 14.6%, and 25.0% for <2, 2-3, and ≥3 log₁₀ IU/mL, respectively). In contrast, TAF discontinuers showed persistently high virological (68.8%-86.3%) and clinical relapse rates (48.5%-57.1%) regardless of EOT qHBsAg level. The relapse risk difference was most pronounced at lower EOT qHBsAg: the sHR for clinical relapse (TAF vs. ETV) reached 5.164 (95% CI 2.131-12.515) at 2-3 log₁₀ IU/mL, with no ETV events at <2 log₁₀ IU/mL. Overall sHR was 5.633 (95% CI 2.801-11.329; p < 0.001).</p><p><strong>Conclusions: </strong>EOT qHBsAg effectively stratifies clinical relapse risk after ETV discontinuation but shows limited discriminative ability after TAF cessation, where relapse rates remain uniformly high across all qHBsAg levels.</p>","PeriodicalId":11378,"journal":{"name":"Digestive Diseases and Sciences","volume":" ","pages":"5939-5947"},"PeriodicalIF":2.8,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148789492","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cardiac Arrests During Inpatient Gastrointestinal Endoscopic Procedures: A United States Nationwide Assessment.","authors":"Spencer R Goble, David Wong Arias, Joseph A Akambase, Thomas M Leventhal","doi":"10.1007/s10620-026-10094-6","DOIUrl":"10.1007/s10620-026-10094-6","url":null,"abstract":"<p><strong>Background: </strong>Major cardiac events can complicate endoscopic procedures. However, the true incidence and outcomes of these events are not well defined.</p><p><strong>Aims: </strong>We aimed to define the true incidence of cardiac arrest during inpatient endoscopic procedures and the associated outcomes.</p><p><strong>Methods: </strong>We performed a cross-sectional retrospective analysis of the National Inpatient Sample from 2016 to 2023. Endoscopic intraprocedural cardiac arrests were identified using ICD-10 diagnostic and procedural codes. Multivariable logistic regression was used to assess patient and procedural factors associated with cardiac arrest. Outcomes among patients experiencing endoscopic intraprocedural cardiac arrest were compared with those of all other cases of in-hospital cardiac arrest.</p><p><strong>Results: </strong>Among 11,137,008 inpatient endoscopic procedures, 1,110 were complicated by cardiac arrest, corresponding to one cardiac arrest per 10,125 procedures. Among assessed patient factors, congestive heart failure had the strongest association with cardiac arrest (aOR = 2.78, 95% CI 2.04-3.78; p < 0.001). Compared with upper endoscopy, colonoscopy was associated with a lower risk of cardiac arrest (aOR = 0.50, 95% CI 0.36-0.69; p < 0.001), while endoscopic retrograde cholangiopancreatography had a similar risk (aOR = 0.75, 95% CI 0.49-1.15; p = 0.183). In-hospital mortality was lower among patients with endoscopy-associated cardiac arrest compared with other cases of in-hospital cardiac arrest (30.6% vs. 71.0%; aOR-0.17, 95% CI 0.13-0.23; p < 0.001).</p><p><strong>Conclusions: </strong>Intraprocedural cardiac arrest is an uncommon complication of inpatient endoscopy. Upper endoscopy carries a higher risk than colonoscopy, and patients with congestive heart failure are at increased risk. Outcomes following endoscopy-associated cardiac arrest are more favorable than for other in-hospital cardiac arrests.</p>","PeriodicalId":11378,"journal":{"name":"Digestive Diseases and Sciences","volume":" ","pages":"5356-5362"},"PeriodicalIF":2.8,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13585844/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148387476","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Endoscopic Hand Suturing After Gastric Endoscopic Submucosal Dissection in Patients with Low to Intermediate Risk of Delayed Bleeding: A Retrospective Pilot Study.","authors":"Zofia Orzeszko, Przemysław Kasprzyk, Urszula Zawada, Kasper Maryńczak, Mirosław Szura, Michał Spychalski","doi":"10.1007/s10620-026-10168-5","DOIUrl":"10.1007/s10620-026-10168-5","url":null,"abstract":"<p><strong>Purpose: </strong>Endoscopic hand suturing (EHS) enables closure of large mucosal defects after gastric endoscopic submucosal dissection (ESD), but evidence on its prophylactic use in patients at low to intermediate risk of delayed bleeding (DB) is limited. This pilot study evaluated the feasibility of EHS following gastric ESD in a Wester setting.</p><p><strong>Methods: </strong>This retrospective pilot study included 46 consecutive patients with low to intermediate DB risk (BEST-J score 0-2) who underwent uneventful gastric ESD between September 2023 and December 2024. Post-ESD defects were closed using EHS (group A, n = 20) or left open (group B, n = 26). Primary outcomes were technical success of closure and DB rate. Secondary outcomes included overall procedure time (OPT), perforation rate, and length of hospital stay (HS).</p><p><strong>Results: </strong>En bloc resection and complete closure were successful in 100% of attempted cases. DB in group A was 0.0% (0/20) versus 7.7% (2/26) in group B (mean difference [MD] 7.7%; 95%CI: - 3.3 to 18.7). OPT was longer in the EHS group (59 ± 19 vs. 35 ± 17 min; MD 23 min; 95%CI: 12-34). No delayed perforations occurred. HS was shorter in group A (2.1 ± 1.0 vs. 2.9 ± 1.1 days; MD 0.8 days; 95%CI: 0.2-1.4).</p><p><strong>Conclusion: </strong>In a Western setting, EHS after gastric ESD is feasible and enables reliable defect closure. However, implementation of EHS is associated with increased procedure time and cost, and its clinical benefit in low- to intermediate-risk patients remains uncertain.</p><p><strong>Clinicaltrials: </strong>gov Identifier: NCT06779266 retrospectively registered.</p>","PeriodicalId":11378,"journal":{"name":"Digestive Diseases and Sciences","volume":" ","pages":"5890-5898"},"PeriodicalIF":2.8,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13585951/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148723073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Leaving No Stone Unturned - Update on the Current Approach to Diagnosing and Treatment of Idiopathic Acute Pancreatitis.","authors":"Ping Yue, Rong Wang, Ke Zhao, Wenbo Meng","doi":"10.1007/s10620-026-10093-7","DOIUrl":"10.1007/s10620-026-10093-7","url":null,"abstract":"","PeriodicalId":11378,"journal":{"name":"Digestive Diseases and Sciences","volume":" ","pages":"5286-5288"},"PeriodicalIF":2.8,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148410643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Utility and Diagnostic Yield of Duodenal Versus Jejunal Aspirates for Small Intestinal Bacterial or Fungal Overgrowth.","authors":"Pearl Princess Uy, Karlo Fidel, Jing Sun, Anabel Liyen Cartelle, Satish S C Rao","doi":"10.1007/s10620-026-10119-0","DOIUrl":"10.1007/s10620-026-10119-0","url":null,"abstract":"<p><strong>Background and aims: </strong>Small intestinal bacterial (SIBO) or fungal overgrowth (SIFO) involves excessive microbial growth in the small intestine. While jejunal aspirate is the gold standard for diagnosis, duodenal aspiration is easier to perform. This study determined and compared the diagnostic yield of tandemly performed duodenal and jejunal aspirates and cultures.</p><p><strong>Methods: </strong>Patients with gas and bloating symptoms and suspected SIBO/SIFO underwent enteroscopy, during which duodenal and jejunal aspirates were sequentially collected using a 2 mm Liguory catheter under aseptic conditions. Cultures were performed for aerobic, anaerobic, and fungal organisms. The endoscopic time, diagnostic yield, and concordance rates were compared.</p><p><strong>Results: </strong>Of 57 patients, 24 (42%) had positive cultures for SIBO and SIFO with diagnostic yield of 33% for both duodenal and jejunal aspirates. The overall concordance rate between duodenal and jejunal aspirates was 82% (47/57), with Cohen's kappa of 0.61. Among positive cases, the concordance was 58% (14/24). Using jejunal aspirates as the gold standard, duodenal aspirates had a sensitivity of 74%, specificity of 87%, positive predictive value of 74%, and negative predictive value of 87%. Aerobes predominated (79%), with 15% anaerobes and 6% fungi. Common aerobes included Streptococcus, Haemophilus, Klebsiella, Rothia, and Neisseria, and anaerobes included Clostridium and Bacteroides, with similar prevalence at both sites. Jejunal aspiration took significantly longer to perform than duodenal (p < 0.001).</p><p><strong>Conclusion: </strong>Duodenal and jejunal aspirates have comparable diagnostic yields for detecting SIBO/SIFO. With similar microbial profiles but shorter procedural time, duodenal aspirates offer a practical and efficient alternative for routine evaluation although may miss diagnosis.</p>","PeriodicalId":11378,"journal":{"name":"Digestive Diseases and Sciences","volume":" ","pages":"5575-5581"},"PeriodicalIF":2.8,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148497209","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Safety and Feasibility of a Patient-Centered Same-Day Polypectomy Referral System: A Single-Center Experience.","authors":"Seung Yong Shin, Min-Jae Kim, Jae Jun Park, Jie-Hyun Kim, Young Hoon Youn, Hyojin Park","doi":"10.1007/s10620-026-10109-2","DOIUrl":"10.1007/s10620-026-10109-2","url":null,"abstract":"<p><strong>Background: </strong>Colon polypectomy is often performed on a separate day following screening colonoscopy, necessitating repeat bowel preparation.</p><p><strong>Aims: </strong>We implemented a novel same-day polypectomy referral system to improve patient convenience and evaluated its clinical outcomes and patient satisfaction compared with conventional elective polypectomy.</p><p><strong>Methods: </strong>We retrospectively analyzed a prospectively maintained database of patients referred for colon polypectomy at a tertiary center between July and December 2017. Polyp characteristics, bowel preparation quality, procedural outcomes, and complications were compared. Patient satisfaction was assessed using a questionnaire.</p><p><strong>Results: </strong>A total of 112 patients were included (same-day polypectomy, n = 57; elective polypectomy, n = 55). The number and location of resected polyps were comparable between groups. Polyps in the same-day group were significantly smaller (6.3 ± 3.2 mm vs. 10.9 ± 8.7 mm, P < 0.001), and bowel preparation quality was lower (mean BBPS 6.8 ± 1.6 vs. 8.4 ± 1.0, P < 0.001). No procedure-related complications occurred in either group. Among respondents, 95% reported satisfaction with the same-day system, most commonly due to avoidance of repeat bowel preparation (71.8%).</p><p><strong>Conclusion: </strong>The same-day polypectomy referral pathway appeared feasible in carefully selected patients with non-complex colorectal polyps and was associated with high satisfaction among questionnaire respondents. Lower bowel preparation quality in the same-day group should be considered when interpreting the findings, and the modest sample size precludes definitive conclusions regarding safety.</p>","PeriodicalId":11378,"journal":{"name":"Digestive Diseases and Sciences","volume":" ","pages":"5582-5591"},"PeriodicalIF":2.8,"publicationDate":"2026-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148497375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}