Current Biology最新文献_第2页

Dancing male riflebirds create a dynamic sensory trajectory that guides female choice. 跳舞的雄性来福鸟创造了一个动态的感官轨迹来引导雌性的选择。

IF 7.5 1区生物学

Current Biology Pub Date : 2025-09-29 DOI: 10.1016/j.cub.2025.09.009

Thomas MacGillavry, Yannick Jadoul, Leonida Fusani

{"title":"Dancing male riflebirds create a dynamic sensory trajectory that guides female choice.","authors":"Thomas MacGillavry, Yannick Jadoul, Leonida Fusani","doi":"10.1016/j.cub.2025.09.009","DOIUrl":"https://doi.org/10.1016/j.cub.2025.09.009","url":null,"abstract":"Sexual displays often consist of multiple signal components that combine to create dynamic, multisensory \"dance\" performances.1,2,3,4,5 However, how signal dynamics guide mate choice remains poorly understood. Deciphering the temporal and rhythmic structure of displays is therefore crucial for understanding their evolution and function. We show that the courtship dances of male Victoria's riflebirds-a bird of paradise endemic to subtropical Australia-involve synchronized visual and acoustic components that begin slowly, subtly accelerate, and culminate in a rapid tempo plateau, during which males flash their yellow gape. All displays that resulted in mating reached this tempo plateau, which was associated with both stronger tempo acceleration and an overall much longer duration of acceleration. Attention holding is likely key to display success, as evidenced by a threshold effect of ∼16 s before any matings occurred, though most displays failed to reach this threshold. We find that higher plateau tempi are clearly associated with mating success, supporting a prevailing hypothesis that female choice generally selects for male performance maxima.6,7 Although we also find suggestive evidence that stronger tempo acceleration and greater rhythmic variability, but not the rate of gape flashes, improve mating success, these effects were not robust, suggesting potential attention-holding functions.4,8,9 Our results reveal a unique and rhythmically intricate temporal structure in riflebird mating dances, where males begin with slow, accelerating movements before creating a stimulating grand finale that guides female choice. The sensory trajectory of sexual signals may thus be a core target of mate choice driving the evolution of complex animal dance performances.","PeriodicalId":11359,"journal":{"name":"Current Biology","volume":" ","pages":""},"PeriodicalIF":7.5,"publicationDate":"2025-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145198687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A RALF-brassinosteroid signaling circuit regulates Arabidopsis hypocotyl cell shape. ralf -油菜素类固醇信号通路调节拟南芥下胚轴细胞形状。

IF 7.5 1区生物学

Current Biology Pub Date : 2025-09-26 DOI: 10.1016/j.cub.2025.09.016

David Biermann, Michelle von Arx, Kristina S Munzert-Eberlein, Kaltra Xhelilaj, David Séré, Martin Stegmann, Grégory Vert, Sebastian Wolf, Timo Engelsdorf, Cyril Zipfel, Julien Gronnier

{"title":"A RALF-brassinosteroid signaling circuit regulates Arabidopsis hypocotyl cell shape.","authors":"David Biermann, Michelle von Arx, Kristina S Munzert-Eberlein, Kaltra Xhelilaj, David Séré, Martin Stegmann, Grégory Vert, Sebastian Wolf, Timo Engelsdorf, Cyril Zipfel, Julien Gronnier","doi":"10.1016/j.cub.2025.09.016","DOIUrl":"https://doi.org/10.1016/j.cub.2025.09.016","url":null,"abstract":"Plant cells survey and modulate their cell walls to control their shape and anisotropic growth. Signaling mediated by the plant steroid hormones brassinosteroids (BR) plays a central role in coordinating cell wall status and cell growth, and alterations in the cell wall-BR feedback loop leads to life-threatening defects in tissue and cellular integrity. How the status of the cell wall is relayed to BR signaling remains largely unclear. Increasing evidence shows that RAPID ALKALANIZATION FACTORs (RALFs), a class of secreted peptides, play structural and signaling roles at the cell surface. Here, we show that loss of RALF signaling mediated by the plasma membrane-localized RALF receptor complex FERONIA (FER)-LORELEI-LIKE GPI-anchor protein 1 (LLG1) leads to defects in cell morphology, organization, and composition of the cell wall-including pectin methylation status-and to an increase in BR signaling. We observed that increase in BR signaling mitigates the cellular defects associated with the loss of FER-mediated RALF signaling. We show that perception of RALF23 promotes the formation and signaling activity of the main BR receptor complex formed by BRASSINOSTEROID INSENSITIVE 1 (BRI1) and BRI1-ASSOCIATED KINASE 1 (BAK1) and that its bioactivity relies on pectin status. Our observations suggest a model in which RALF peptides operate at the nexus between cell wall status and BR signaling, capable of inducing changes in the cell wall as well as functioning as a cell-wall-informed signaling cues initiating a feedback loop that solicits BR signaling and coordinates cell morphogenesis.","PeriodicalId":11359,"journal":{"name":"Current Biology","volume":" ","pages":""},"PeriodicalIF":7.5,"publicationDate":"2025-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145181813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Reduced oxytocin signaling in the dBNST drives the transition from acute pain to persistent anxiety. dBNST中催产素信号的减少推动了从急性疼痛到持续焦虑的转变。

IF 7.5 1区生物学

Current Biology Pub Date : 2025-09-26 DOI: 10.1016/j.cub.2025.09.012

Shunchang Fang, Yuxin Qin, Hanbing Lian, Yufang Zhong, Yishuai Yang, Xiao-Dan Yu, Shana Yang, Jiankai Liang, Wenhui Xiao, Songhai Wen, Xiao Min Zhang, Boxing Li, Lianyan Huang

{"title":"Reduced oxytocin signaling in the dBNST drives the transition from acute pain to persistent anxiety.","authors":"Shunchang Fang, Yuxin Qin, Hanbing Lian, Yufang Zhong, Yishuai Yang, Xiao-Dan Yu, Shana Yang, Jiankai Liang, Wenhui Xiao, Songhai Wen, Xiao Min Zhang, Boxing Li, Lianyan Huang","doi":"10.1016/j.cub.2025.09.012","DOIUrl":"https://doi.org/10.1016/j.cub.2025.09.012","url":null,"abstract":"Transient sensory experiences can trigger sustained emotional disturbances, yet the underlying neural mechanisms remain unclear. Here, we show that acute pain induces persistent anxiety in male mice, independent of ongoing nociceptive input, through reduced oxytocin signaling in the dorsal bed nucleus of the stria terminalis (dBNST). Reactivating oxytocin receptors (Oxtrs) in the dBNST markedly alleviated anxiety-like behaviors following pain resolution. Mechanistically, chemogenetic inhibition of somatostatin-expressing (SST) neurons in the dBNST (dBNSTSST neurons) abolished oxytocin's anxiolytic effects, while pharmacological blockade or selective knockdown of Oxtrs in these neurons increased anxiety-like behaviors. Transcriptomic and electrophysiological analyses further revealed that alterations in synaptic transmission and intrinsic excitability participate in this anxiety state. Together, these findings define a multilevel framework-spanning molecular, cellular, and circuit mechanisms-by which acute sensory input induces long-term emotional dysregulation. This study advances our understanding of pain-related affective disorders and highlights oxytocin signaling and dBNSTSST neurons as promising therapeutic targets.","PeriodicalId":11359,"journal":{"name":"Current Biology","volume":" ","pages":""},"PeriodicalIF":7.5,"publicationDate":"2025-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145181878","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Visual circuitry for distance estimation in Drosophila. 果蝇距离估计的视觉回路。

IF 7.5 1区生物学

Current Biology Pub Date : 2025-09-26 DOI: 10.1016/j.cub.2025.09.008

Joseph W Shomar, Elizabeth E Wu, Braedyn Au, Kate Maier, Baohua Zhou, Natalia C B Matos, Garrett Sager, Gustavo M Santana, Ryosuke Tanaka, Caitlin Gish, Damon A Clark

{"title":"Visual circuitry for distance estimation in Drosophila.","authors":"Joseph W Shomar, Elizabeth E Wu, Braedyn Au, Kate Maier, Baohua Zhou, Natalia C B Matos, Garrett Sager, Gustavo M Santana, Ryosuke Tanaka, Caitlin Gish, Damon A Clark","doi":"10.1016/j.cub.2025.09.008","DOIUrl":"https://doi.org/10.1016/j.cub.2025.09.008","url":null,"abstract":"Animals must infer the three-dimensional structure of their environment from two-dimensional retinal images. They use visual cues like motion parallax and binocular disparity to judge distances to objects, and studies across several animal models have found and characterized neural signals that correlate with visual distance. However, the causal role of these neurons in distance estimation and the range of their possible neural properties remain poorly understood. Here, we show that both directional and non-directional feature-selective neurons in the Drosophila visual system are involved in estimating distance during free locomotion. We used a high-throughput behavioral assay to perform a targeted silencing screen of visual neurons, and we subsequently characterized distance tuning using in vivo two-photon microscopy, thus linking distance perception directly to neural signals. Silencing the primary motion detectors eliminated distance-dependent behavior, consistent with reliance on motion parallax. Our screen also identified a visual feature-detecting neuron that encodes a non-canonical motion parallax signal: the signal is not direction selective for object or background motion, but it is tuned to the relative speeds of foreground and background, resulting in a signal that can measure relative distance. Our results demonstrate the behavioral roles of direction-selective and distance-tuned neurons in fly distance estimation and provide a framework for considering broader classes of neurons that encode distance through motion parallax.","PeriodicalId":11359,"journal":{"name":"Current Biology","volume":" ","pages":""},"PeriodicalIF":7.5,"publicationDate":"2025-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145181867","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Store-independent activation of STIM1-ORAI1 by SPCA2 determines the basal CFTR activity in secretory epithelial cells. SPCA2对STIM1-ORAI1的非依赖性激活决定了分泌性上皮细胞中CFTR的基础活性。

IF 7.5 1区生物学

Current Biology Pub Date : 2025-09-26 DOI: 10.1016/j.cub.2025.09.006

Aletta Kata Kiss, Árpád Varga, Marietta Görög, Tamara Madácsy, Woo Young Chung, Petra Pallagi, Viktória Szabó, Petra Susánszki, Enikő Kúthy-Sutus, Dániel Varga, Péter Bíró, Ingrid Hegnes Sendstad, Tim Crul, Boldizsár Jójárt, Bálint Tél, Zsófia Horváth, Szintia Barnai, Anita Balázs, György Lázár, Miklós Erdélyi, Shmuel Muallem, József Maléth

{"title":"Store-independent activation of STIM1-ORAI1 by SPCA2 determines the basal CFTR activity in secretory epithelial cells.","authors":"Aletta Kata Kiss, Árpád Varga, Marietta Görög, Tamara Madácsy, Woo Young Chung, Petra Pallagi, Viktória Szabó, Petra Susánszki, Enikő Kúthy-Sutus, Dániel Varga, Péter Bíró, Ingrid Hegnes Sendstad, Tim Crul, Boldizsár Jójárt, Bálint Tél, Zsófia Horváth, Szintia Barnai, Anita Balázs, György Lázár, Miklós Erdélyi, Shmuel Muallem, József Maléth","doi":"10.1016/j.cub.2025.09.006","DOIUrl":"https://doi.org/10.1016/j.cub.2025.09.006","url":null,"abstract":"Cystic fibrosis transmembrane conductance regulator (CFTR) determines epithelial ion secretion, which is fundamental in various organs. The synergy between cyclic AMP (cAMP) and Ca2+ signaling fine-tunes CFTR-mediated secretion; however, the organization of such signaling complexes and their physiological impact remained largely unknown. Here, we identified an apical membrane signaling complex consisting of secretory pathway Ca2+-ATPase (SPCA2), stromal interaction molecule 1 (STIM1)/calcium release-activated calcium channel protein 1 (ORAI1), adenylyl cyclases, and CFTR. In this complex, SPCA2 facilitates constitutive, store-independent but STIM1-dependent ORAI1-mediated Ca2+ influx by activating ORAI1 and promoting STIM1/ORAI1 interaction, which is essential for basal CFTR function. Analysis by super-resolution dSTORM revealed constitutive organization of the proteins in a nanodomain on the apical membrane, which translates local Ca2+ increases to cAMP elevation and CFTR activation in unstimulated cells required for ion secretion. The same system operates in the pancreas, airways, and liver. Our findings reveal an essential, self-directing regulatory mechanism of CFTR-mediated ion secretion in secretory epithelial cells, independent from neurohormonal stimuli.","PeriodicalId":11359,"journal":{"name":"Current Biology","volume":" ","pages":""},"PeriodicalIF":7.5,"publicationDate":"2025-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145181785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Central clock drives foraging rhythm through modulating food odor attraction in Drosophila. 果蝇的中央时钟通过调节食物气味吸引来驱动觅食节奏。

IF 7.5 1区生物学

Current Biology Pub Date : 2025-09-26 DOI: 10.1016/j.cub.2025.09.011

Mingmin Zhou, Meijun Zheng, Xiaohang Zhang, Xin Liu, Jing Guo, Xichu Cao, Aike Guo, Yan Li

引用次数: 0

Waggle-dance-recruited honeybees expect landscape structures. 摇摆舞招募的蜜蜂期待景观结构。

IF 7.5 1区生物学

Current Biology Pub Date : 2025-09-24 DOI: 10.1016/j.cub.2025.08.055

Zhengwei Wang, Jana Mach, Xiuxian Chen, Randolf Menzel

{"title":"Waggle-dance-recruited honeybees expect landscape structures.","authors":"Zhengwei Wang, Jana Mach, Xiuxian Chen, Randolf Menzel","doi":"10.1016/j.cub.2025.08.055","DOIUrl":"https://doi.org/10.1016/j.cub.2025.08.055","url":null,"abstract":"Honeybee foragers explore the environment before they start foraging, following dances, or performing dances. Foragers are therefore familiar with the landscape surrounding the hive during their foraging career. Here, we ask whether dance-recruited honeybees expect the landscape features that the dancer experienced during its outbound foraging flights. If this were the case, the dance-recruited honeybees would behave differently according to whether the landscape features they experienced during their outbound flight matched the expected features. In our experiments, the dance followers (recruits) had explored the environment around the hive, and the dancers flew along an elongated ground structure (a gravel road) running approximately northward from the hive in the outbound condition. The flights of the recruits were recorded by harmonic radar. The recruits were released not only at the hive but also at two remote sites within the explored area, where they faced either a similar north-running gravel road or even grassland. We found that the recruits released from the remote sites performed flights more similar to those of the hive-released bees when they experienced a similar elongated ground structure. This behavior did not result from a spontaneous or learned tendency to follow elongated ground structures as documented by control experiments. We conclude that dance-recruited honeybees expect the salient landscape structures that the dancer experienced, although the dance message includes only vector information.","PeriodicalId":11359,"journal":{"name":"Current Biology","volume":" ","pages":""},"PeriodicalIF":7.5,"publicationDate":"2025-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145148238","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Delayed recovery of seed-dispersal interactions after deforestation. 森林砍伐后种子传播相互作用的延迟恢复。

IF 7.5 1区生物学

Current Biology Pub Date : 2025-09-24 DOI: 10.1016/j.cub.2025.08.070

Anna R Landim, Jörg Albrecht, Jorge Brito, Santiago Burneo, Santiago Erazo, Felicity L Newell, Boris A Tinoco, Marco Tschapka, Eike Lena Neuschulz, Matthias Schleuning

{"title":"Delayed recovery of seed-dispersal interactions after deforestation.","authors":"Anna R Landim, Jörg Albrecht, Jorge Brito, Santiago Burneo, Santiago Erazo, Felicity L Newell, Boris A Tinoco, Marco Tschapka, Eike Lena Neuschulz, Matthias Schleuning","doi":"10.1016/j.cub.2025.08.070","DOIUrl":"https://doi.org/10.1016/j.cub.2025.08.070","url":null,"abstract":"Deforestation has reduced the area of old-growth tropical forests, making restoration essential to recover biodiversity. Because most tropical plants rely on seed dispersal by animals, plant-animal interactions are crucial for natural forest recovery. Yet, the recovery time of seed-dispersal interactions is still unknown and likely depends on both local and landscape-scale factors, such as habitat suitability and connectivity to the surrounding forest. We conducted an empirical study in 62 plots along a 40-year chronosequence of forest recovery in the Ecuadorian Chocó, covering plots in active agricultural land, recovering forests, and old-growth forests, differing in their connectivity to the surrounding forest. In each plot, we recorded interactions between fleshy-fruited plants and frugivorous animals and measured key functional traits related to seed-dispersal interactions. Using a Bayesian model, we estimated the recovery times for the functional diversity of plants, animals, and their interactions contingent on patch connectivity. Due to the presence of remnant trees, plant functional diversity was similarly high as in old-growth forests shortly after deforestation. At mean levels of patch connectivity, animal functional diversity required 40 years to recover, and seed-dispersal interactions recovered after 19 years. The functional diversity of interactions needed more than 30 years to recover at low levels of patch connectivity. Our results show that seed-dispersal interactions can require several decades to functionally recover, depending on the connectivity to the surrounding forest. This finding provides a new benchmark for the timing of tropical forest restoration that critically depends on re-establishing functionally diverse seed-dispersal interactions.","PeriodicalId":11359,"journal":{"name":"Current Biology","volume":" ","pages":""},"PeriodicalIF":7.5,"publicationDate":"2025-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145148271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Olfactory floral mimicry of injured ants mediates the attraction of kleptoparasitic fly pollinators. 受伤蚂蚁的嗅觉花卉模仿介导了盗寄生蝇传粉者的吸引力。

IF 7.5 1区生物学

Current Biology Pub Date : 2025-09-24 DOI: 10.1016/j.cub.2025.08.060

Ko Mochizuki

{"title":"Olfactory floral mimicry of injured ants mediates the attraction of kleptoparasitic fly pollinators.","authors":"Ko Mochizuki","doi":"10.1016/j.cub.2025.08.060","DOIUrl":"https://doi.org/10.1016/j.cub.2025.08.060","url":null,"abstract":"Specialized pollination by flies often involves specific floral mimicry of various food and brood substrates.1,2,3 However, identifying a precise model is challenging due to the ecological diversity of flies, which subject plants to diverse selection pressures.4,5 Here, I report that Vincetoxicum nakaianum (Apocynaceae) lures kleptoparasitic fly pollinators by producing a floral scent mimicking the volatiles released by injured ants. Field observations confirmed that V. nakaianum is pollinated by four kleptoparasitic chloropid fly species that feed on the body fluids of injured insects.6,7,8,9,10 In chemical analysis of floral scent, nonane, undecane, octyl acetate (8Ac), decyl acetate (10Ac), and methyl-6-methyl salicylate (6-MMS)11,12,13 were identified consistently across all samples. A synthetic mixture of these five floral scent components was attractive to pollinating flies. However, in the absence of 10Ac or 6-MMS, the mixture was unattractive to flies. When 10Ac and 6-MMS were offered in combination, flies were attracted; these two compounds alone were, however, not attractive. The compositions of volatiles emitted from injured Formica ants closely resembled V. nakaianum floral scent, sharing 10Ac and 6-MMS. Y-maze experiments confirmed that pollinators were attracted to Formica japonica following spider attack. These results indicate that V. nakaianum employs the olfactory mimicry of injured ants to attract pollinators. Although ants are pervasive and frequently interact with plants, no flowers have been reported to mimic ants. This study highlights the diverse evolutionary outcomes of adaptation to fly pollinators and the evolutionary capacity of ant mimicry in plants.","PeriodicalId":11359,"journal":{"name":"Current Biology","volume":" ","pages":""},"PeriodicalIF":7.5,"publicationDate":"2025-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145148303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Chitooligosaccharide receptors modulate root microbiota to enhance symbiosis and growth in Medicago. 壳寡糖受体调节根微生物群促进紫花苜蓿共生和生长。

IF 7.5 1区生物学

Current Biology Pub Date : 2025-09-24 DOI: 10.1016/j.cub.2025.09.045

Jing-Mei Qian, Kangping Li, Weidong Liu, Jingyi Zhang, Allan Wylie, Brian Arnall, Mark J Krzmarzick, Ertao Wang, Giles E D Oldroyd, Yang Bai, Feng Feng, Jingying Zhang

引用次数: 0