Drug and alcohol review最新文献

{"title":"Analysis of Methamphetamine-Related Deaths: A Retrospective Cross-Sectional Study","authors":"Arif Garbioğlu,&nbsp;Hacı Altay","doi":"10.1111/dar.70241","DOIUrl":"https://doi.org/10.1111/dar.70241","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Methamphetamine use and related mortality have increased worldwide, yet forensic data from Turkey remain limited.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This retrospective cross-sectional autopsy study investigated the demographic, toxicological and medicolegal characteristics of methamphetamine-related deaths in Zonguldak, Turkey, between 2015 and 2025. Among the 1863 forensic autopsies, 30 cases with analytically confirmed methamphetamine positivity were included.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The mean age was 33.4 ± 8.7 years and 90.0% of the cases were male. The highest annual proportion of forensic autopsies with methamphetamine detected was observed in 2023. Accidental death was the most common manner of death and methamphetamine toxicity was the leading cause of death. All natural deaths were attributed to cardiovascular disease. Polydrug use was present in 56.7% of the cases.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Discussion and Conclusions</h3>\u0000 \u0000 <p>Our findings indicate that methamphetamine-related deaths in Turkey share demographic and forensic characteristics with international reports and underscore the growing medicolegal and public health burden associated with stimulant use.</p>\u0000 </section>\u0000 </div>","PeriodicalId":11318,"journal":{"name":"Drug and alcohol review","volume":"45 6","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-08-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/dar.70241","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148784189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ethnic Disparities in Police Diversion and Criminalisation for Drug Possession in England: A Study of 32,758 Incidents","authors":"Ashley Mills,&nbsp;Dan Lewer,&nbsp;Guillermo Reyes Pascual,&nbsp;Nadine Hendrie,&nbsp;Paul Quinton,&nbsp;Matthew Bacon,&nbsp;Alex Stevens","doi":"10.1111/dar.70230","DOIUrl":"https://doi.org/10.1111/dar.70230","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Police-led drug diversion schemes have expanded across England, yet little is known about whether their use reproduces established ethnic disparities in policing outcomes.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Using individual-level data from 32,758 incidents recorded by 15 police forces (covering 38% of England's population), we conducted a cohort study to estimate ethnic differences in the likelihood of: (i) being offered diversion for suspected drug possession; and (ii) receiving a criminal sanction. Mixed-effects logistic regression models were used to adjust for age, sex, suspected drug type and police-force area, with missing data addressed via Bayesian chained imputation.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>We found substantial disparities. Compared with White suspects, Black suspects had significantly lower odds of receiving an offer of diversion (odds ratio 0.75, 95% confidence interval 0.65–0.87), while Asian suspects had significantly higher odds (odds ratio 1.25, 95% confidence interval 1.09–1.43). For criminalisation, Asian suspects were less likely than White suspects to receive a criminal sanction (odds ratio 0.81, 95% confidence interval 0.74–0.89), while Black suspects showed no statistically significant difference.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Discussion and Conclusions</h3>\u0000 \u0000 <p>These findings extend long-standing evidence of unequal policing, showing that ethnic disparities persist at the earliest decision points of drug law enforcement—even within schemes intended to reduce criminalisation. The results underscore the need for police forces to monitor and remediate disproportionality in diversion decisions. Future work should investigate mechanisms underpinning officers' diversion decisions and assess whether differential access to diversion contributes to cumulative inequalities in police-community relations and downstream criminal justice outcomes.</p>\u0000 </section>\u0000 </div>","PeriodicalId":11318,"journal":{"name":"Drug and alcohol review","volume":"45 6","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-08-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/dar.70230","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148784190","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Confusing Uncertainty With Bias: The Challenges of Working With Real-World Data","authors":"Jack Wilson,&nbsp;Matthew Sunderland,&nbsp;Siobhan O'Dean,&nbsp;Tim Slade,&nbsp;Danielle Dawson,&nbsp;Olivia Dobson,&nbsp;Janni Leung,&nbsp;Gary Chan,&nbsp;Maree Teesson,&nbsp;Wayne Hall,&nbsp;Nicola Newton,&nbsp;Valentina Lorenzetti,&nbsp;Emily Stockings","doi":"10.1111/dar.70242","DOIUrl":"https://doi.org/10.1111/dar.70242","url":null,"abstract":"","PeriodicalId":11318,"journal":{"name":"Drug and alcohol review","volume":"45 6","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148753618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Experiences of Healthcare Support and Access Among Women Who Use Performance and Image-Enhancing Drugs","authors":"Hannah C. Schuurs,&nbsp;Zoe Walter,&nbsp;Leanne Hides,&nbsp;Mair Underwood","doi":"10.1111/dar.70227","DOIUrl":"10.1111/dar.70227","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Women who use performance and image-enhancing drugs (PIED) face distinct health risks, yet little is known about how they engage with healthcare or seek support. This study explored how women who use PIEDs navigate healthcare, with a focus on engagement, disclosure and stigma.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Method</h3>\u0000 \u0000 <p>An interpretative phenomenological analysis was undertaken, involving semi-structured interviews with nine women with current/historical experience of PIED use, and engagement in regular weight training. Interviews explored health monitoring, support-seeking, and experiences with healthcare services and providers in the context of their PIED use.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Participants described healthcare experiences ranging from respectful, supportive care to dismissal, judgement and clinical uncertainty. Three interrelated themes were identified: (i) participants' proactive engagement in health monitoring and healthcare to manage risks associated with PIED use; (ii) systemic barriers and knowledge gaps within healthcare, which made appropriate care difficult to access and navigate and, at times, shifted the burden of expertise onto participants within clinical encounters; and (iii) the importance of non-judgemental care, with stigma and fear of judgement shaping disclosure, trust and help-seeking.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Discussion and Conclusions</h3>\u0000 \u0000 <p>This study provides an in-depth qualitative account of how women who use PIEDs engage with and navigate healthcare. Despite strong health motivation and proactive risk management, participants often encountered structural and interpersonal barriers to care. Respectful, non-judgemental interactions were central to positive healthcare engagement and sometimes more influential than clinical expertise alone. Findings highlight the need for improved professional education and gender-sensitive, harm-reduction-oriented resources to support women who use PIEDs.</p>\u0000 </section>\u0000 </div>","PeriodicalId":11318,"journal":{"name":"Drug and alcohol review","volume":"45 6","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/dar.70227","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148720052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Making Veterans Visible in Australia's Alcohol and Other Drug Services: Leveraging the Alcohol and Other Drug National Quality Framework","authors":"Jane Fischer,&nbsp;Andrew Prevett,&nbsp;Kirrilly Thompson","doi":"10.1111/dar.70236","DOIUrl":"10.1111/dar.70236","url":null,"abstract":"<p>Many veterans seek alcohol and other drug (AOD) care in mainstream services, where veteran status is not routinely identified. This limits the sector's capacity to recognise veterans' needs, plan appropriate responses and assess outcomes. This commentary examines the implications of the Royal Commission into Defence and Veteran Suicide for Australia's AOD sector. It argues that embedding veteran identification within existing accreditation processes under the AOD National Quality Framework offers a practical means of strengthening military cultural capability and improving responsiveness to veterans' needs. Although this approach does not resolve all structural challenges, it provides a concrete starting point for improving recognition and care for veterans within Australia's AOD treatment system.</p>","PeriodicalId":11318,"journal":{"name":"Drug and alcohol review","volume":"45 6","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-08-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/dar.70236","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148720334","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Regional COVID-19 Lockdowns on Alcohol Use and Smoking in Two Chilean University Communities: A Difference-In-Difference Analysis","authors":"Sebastián Peña,&nbsp;Daniela Palet,&nbsp;Camila Salazar-Fernández,&nbsp;Francisca Román Mella","doi":"10.1111/dar.70229","DOIUrl":"10.1111/dar.70229","url":null,"abstract":"&lt;div&gt;\u0000 \u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Introduction&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;Effects of lockdowns on alcohol use and smoking remain unclear. By exploiting the variation in regional COVID-19 lockdowns in two Chilean regions, we examined their effect on alcohol use and smoking in two university communities.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Methods&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;We conducted a quasi-experimental study in university communities in two Chilean regions, Coquimbo and Araucanía. Participants were a longitudinal cohort (&lt;i&gt;n&lt;/i&gt; = 896) assessed seven times from July 2020 (&lt;span&gt;&lt;/span&gt;&lt;math&gt;\u0000 &lt;semantics&gt;\u0000 &lt;mrow&gt;\u0000 &lt;msub&gt;\u0000 &lt;mi&gt;t&lt;/mi&gt;\u0000 &lt;mn&gt;1&lt;/mn&gt;\u0000 &lt;/msub&gt;\u0000 &lt;/mrow&gt;\u0000 &lt;annotation&gt;$$ {t}_1 $$&lt;/annotation&gt;\u0000 &lt;/semantics&gt;&lt;/math&gt;) to April 2021 (&lt;span&gt;&lt;/span&gt;&lt;math&gt;\u0000 &lt;semantics&gt;\u0000 &lt;mrow&gt;\u0000 &lt;msub&gt;\u0000 &lt;mi&gt;t&lt;/mi&gt;\u0000 &lt;mn&gt;7&lt;/mn&gt;\u0000 &lt;/msub&gt;\u0000 &lt;/mrow&gt;\u0000 &lt;annotation&gt;$$ {t}_7 $$&lt;/annotation&gt;\u0000 &lt;/semantics&gt;&lt;/math&gt;). Outcomes were weekly grams of alcohol use, heavy episodic drinking (HED) and cigarettes smoked per day.&lt;/p&gt;\u0000 &lt;/section&gt;\u0000 \u0000 &lt;section&gt;\u0000 \u0000 &lt;h3&gt; Results&lt;/h3&gt;\u0000 \u0000 &lt;p&gt;Lockdown between &lt;span&gt;&lt;/span&gt;&lt;math&gt;\u0000 &lt;semantics&gt;\u0000 &lt;mrow&gt;\u0000 &lt;msub&gt;\u0000 &lt;mi&gt;t&lt;/mi&gt;\u0000 &lt;mn&gt;1&lt;/mn&gt;\u0000 &lt;/msub&gt;\u0000 &lt;/mrow&gt;\u0000 &lt;annotation&gt;$$ {t}_1 $$&lt;/annotation&gt;\u0000 &lt;/semantics&gt;&lt;/math&gt; and &lt;span&gt;&lt;/span&gt;&lt;math&gt;\u0000 &lt;semantics&gt;\u0000 &lt;mrow&gt;\u0000 &lt;msub&gt;\u0000 &lt;mi&gt;t&lt;/mi&gt;\u0000 &lt;mn&gt;3&lt;/mn&gt;\u0000 &lt;/msub&gt;\u0000 &lt;/mrow&gt;\u0000 &lt;annotation&gt;$$ {t}_3 $$&lt;/annotation&gt;\u0000 &lt;/semantics&gt;&lt;/math&gt; was associated with an increase of 15.6 g of alcohol used per week (95% confidence interval 1.8; 29.3) and an increase of 0.3 daily cigarettes smoked (95% confidence interval 0.003; 0.5) at &lt;span&gt;&lt;/span&gt;&lt;math&gt;\u0000 &lt;semantics&gt;\u0000 &lt;mrow&gt;\u0000 &lt;msub&gt;\u0000 &lt;mi&gt;t&lt;/mi&gt;\u0000 &lt;mn&gt;3&lt;/mn&gt;\u0000 &lt;/msub&gt;\u0000 &lt;/mrow&gt;\u0000 &lt;annotation&gt;$$ {t}_3 $$&lt;","PeriodicalId":11318,"journal":{"name":"Drug and alcohol review","volume":"45 6","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/dar.70229","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148711420","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessing the Concurrent Validity of the Australian Treatment Outcomes Profile in a Methamphetamine Dependent Treatment-Seeking Population","authors":"Brendan Clifford,&nbsp;Rachel M. Deacon,&nbsp;Kristie Mammen,&nbsp;Krista J. Siefried,&nbsp;Nadine Ezard,&nbsp;Nicholas Lintzeris","doi":"10.1111/dar.70224","DOIUrl":"10.1111/dar.70224","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>The Australian Treatment Outcomes Profile (ATOP) is a brief clinical tool assessing substance use, health and well-being used in Australian alcohol and other drug treatment services. It is validated for use with clients using alcohol, opioids and cannabis, but not yet for clients who primarily use methamphetamine.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>An embedded validation study was undertaken in treatment-seeking adults enrolled in a randomised double-blind placebo-controlled trial of lisdexamfetamine for methamphetamine dependence with sites in New South Wales, South Australia and Victoria. Participant demographics were collected during study screening. The ATOP and comparators (Time Line Follow Back, Opiate Treatment Index, Depression Anxiety Stress Scale, WHOQOL-BREF and Personal Wellbeing Index) were collected at baseline. Continuous ATOP items were analysed using Pearson's correlation coefficient, and dichotomous items were analysed using Fleiss's <i>κ</i>. Agreement was rated as strong where measures were ≥ 0.50, moderate where agreement was 0.30–0.49, and weak where &lt; 0.30.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>One hundred and eighteen study participants (2018–2020) had data for concurrent validity analysis. Strong validity was demonstrated for physical health, psychological health, quality of life, injecting drug use and crime items, and for days of use for amphetamines, alcohol, cannabis and cocaine. There was weak validity for days of use for benzodiazepines. Heroin use days and other opioid use days were endorsed by fewer than five participants and were therefore unable to be assessed.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Discussion and Conclusions</h3>\u0000 \u0000 <p>The ATOP is valid for use in a treatment-seeking methamphetamine-dependent population, expanding the range of tools for assessment and standardised outcome monitoring across different settings and services.</p>\u0000 </section>\u0000 </div>","PeriodicalId":11318,"journal":{"name":"Drug and alcohol review","volume":"45 6","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/dar.70224","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148705870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Simultaneous versus Sequential Cessation of Tobacco and Cannabis: Preferences of Young Adults Who Co-Use in France","authors":"Tangui Barré,&nbsp;Géraldine Cazorla,&nbsp;Vincent Leroy,&nbsp;Gwenaëlle Maradan,&nbsp;Clotilde Couderc,&nbsp;Julia de Ternay,&nbsp;Carlotta Magnani,&nbsp;Patrizia Carrieri","doi":"10.1111/dar.70221","DOIUrl":"10.1111/dar.70221","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Co-use of tobacco and cannabis is common among young adults and is associated with higher dependence and quitting difficulties. Little is known about the preference for simultaneous or sequential dual cessation in this population. We aimed to explore preferences for the timing of dual cessation and the methods most likely to be used by young adults who co-use.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Data came from an online nationwide cross-sectional survey of people co-using tobacco and cannabis in France. Preferences for the timing of dual cessation were modelled using binary logistic and multinomial regressions among participants aged 18–30 years. We also described cessation methods (for tobacco and cannabis separately) previously tried and those considered likely to be used in future quit attempts.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Among 357 young adults (54.9% men; median age 24), those using tobacco daily and cannabis ≥ 20 days/month had a 56% lower likelihood of preferring simultaneous over sequential cessation (adjusted odds ratio 0.44 [0.21–0.90], <i>p</i> = 0.024) compared with participants with the least frequent co-use. Participants who perceived their tobacco use as more harmful than their cannabis use were more likely to prefer quitting tobacco first. Across past and future attempts, the most cited methods for both substances were sport, cannabidiol, electronic cigarettes and nicotine replacement therapy.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Discussion and Conclusions</h3>\u0000 \u0000 <p>Simultaneous cessation appeared more acceptable to young adults with lower-risk co-use patterns. Overall, the likelihood of using recommended cessation methods was low. Further research is needed to develop effective and acceptable sequential cessation strategies for young adults who co-use these substances.</p>\u0000 </section>\u0000 </div>","PeriodicalId":11318,"journal":{"name":"Drug and alcohol review","volume":"45 6","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13453397/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148700977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Characterising the Beyond 50 Cohort: Preliminary Exploration of Physical and Psychosocial Health Factors and Substance Use Among a Cohort of Community Dwelling Adults Aged 50–70 Years","authors":"Rose Laing,&nbsp;Tina Lam,&nbsp;Bosco Rowland,&nbsp;Paul Dietze,&nbsp;Aislinn Lalor,&nbsp;Keith D. Hill,&nbsp;Laura Alfrey,&nbsp;Nadine E. Andrew,&nbsp;Shalini Arunogiri,&nbsp;Stephen Bright,&nbsp;Louisa Picco,&nbsp;Suzanne Nielsen","doi":"10.1111/dar.70228","DOIUrl":"10.1111/dar.70228","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Older adults exhibit unique risks associated with poor mental health and substance use. The Beyond 50 study is a longitudinal cohort investigating the determinants of healthy ageing, including relationships between physical and psychosocial health and substance use. We aim to characterise the Beyond 50 cohort and explore patterns of physical and psychosocial health and substance use.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Baseline data collection was completed between September 2023 and August 2024. Annual follow-up data collection commenced in September 2024. Descriptive statistics will be used to characterise the cohort at the time of baseline survey completion.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Of the 1059 participants, the mean age was 61 years (standard deviation 0.2 years) and 46.8% were female. Just over half (52.4%, <i>n</i> = 555) received a positive screen for potentially hazardous alcohol consumption (past 12-month use), 8.7% (<i>n</i> = 92) reported recent tobacco use, 3.7% (<i>n</i> = 39) reported recent cannabis use and 5.5% (<i>n</i> = 58) reported other nonmedical substance use. Twelve percent (<i>n</i> = 134) screened positive for the symptoms of moderate to severe anxiety, 16.4% (<i>n</i> = 174) screened positive for the symptoms of moderate to severe depression, 15.7% (<i>n</i> = 166) were moderately to severely lonely and 22.6% (<i>n</i> = 239) reported being dissatisfied with their social relationships.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Discussion and Conclusion</h3>\u0000 \u0000 <p>The Beyond 50 cohort displays high rates of alcohol use, with levels of social isolation, loneliness, anxiety and depression comparable to the broader Victoria population. This lends to the cohort's ability to provide further insight into factors that affect healthy ageing and will allow for detailed analysis into the impacts of various physical and psychosocial factors on overall health and wellbeing.</p>\u0000 </section>\u0000 </div>","PeriodicalId":11318,"journal":{"name":"Drug and alcohol review","volume":"45 6","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13453339/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148700936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring the Dose–Response Relationship Between Alcohol Consumption and Harm to Others in Australia","authors":"Koen Smit,&nbsp;Heng Jiang,&nbsp;Katherine J. Karriker-Jaffe,&nbsp;Anne-Marie Laslett","doi":"10.1111/dar.70226","DOIUrl":"10.1111/dar.70226","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Alcohol consumption often leads to harm to individuals other than the drinker. Yet, few studies have quantified an exposure-response gradient using “nominated” drinkers' alcohol volume and their heavy episodic drinking (HED) frequency to predict harm-type burden and overall severity among people harmed by someone else's alcohol use. We examined these dose–response relationships across sociodemographic groups.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Data were drawn from the cross-sectional Australian 2021 Alcohol's Harm to Others (AHTO) Survey. A total of 2574 adults (18+ years) participated, of whom 554 reported harm from another person's drinking in the past 12 months. Respondents identified the person who harmed them the most (the “nominated drinker”) and reported on the person's weekly alcohol volume and frequency of HED. Harms experienced included an overall harm score (0–10 scale) and a count of 14 specific harms.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>There was a significant positive dose–response relationship between the nominated drinker's alcohol consumption (both weekly volume and frequency of HED) and the degree of harm experienced by respondents. Although subgroup analyses suggested stronger effects among women, younger respondents, and when the drinker was a (former) partner, these differences were not statistically significant.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Discussion and Conclusions</h3>\u0000 \u0000 <p>Greater alcohol consumption and more frequent HED are associated with more severe harms to others, regardless of respondents' sociodemographic background. A clear dose–response relationship exists between alcohol consumption by a known drinker and harm to others. The dose–response gradient was stronger at higher exposure levels, suggesting that reducing very frequent heavy drinking may yield disproportionately larger reductions in AHTO burden.</p>\u0000 </section>\u0000 </div>","PeriodicalId":11318,"journal":{"name":"Drug and alcohol review","volume":"45 6","pages":""},"PeriodicalIF":2.9,"publicationDate":"2026-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13449624/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148683871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}