Advanced Functional Materials最新文献_第9页

Unlocking the Origin of High-Temperature Superconductivity in Molecular Hydrides at Moderate Pressures 揭开分子氢化物在中等压力下高温超导性的起源

IF 19 1区材料科学

Advanced Functional Materials Pub Date : 2024-11-18 DOI: 10.1002/adfm.202415910

Wendi Zhao, Austin Ellis, Defang Duan, Hongwei Wang, Qiwen Jiang, Mingyang Du, Tian Cui, Maosheng Miao

{"title":"Unlocking the Origin of High-Temperature Superconductivity in Molecular Hydrides at Moderate Pressures","authors":"Wendi Zhao, Austin Ellis, Defang Duan, Hongwei Wang, Qiwen Jiang, Mingyang Du, Tian Cui, Maosheng Miao","doi":"10.1002/adfm.202415910","DOIUrl":"https://doi.org/10.1002/adfm.202415910","url":null,"abstract":"The current pressing challenge in the field of superconducting hydride research is to lower the stable pressure of such materials for practical applications. Molecular hydrides are usually stable under moderate pressure, but the underlying metallization mechanism remains elusive. Here, the important role of chemical interactions in governing the structures and properties of molecular hydrides is demonstrated. A new mechanism is proposed for obtaining high-temperature and even room-temperature superconductivity in molecular hydrides and report that the ternary hydride NaKH12 hosts Tc values up to 245 K at moderate pressure of 60 GPa. Both the excellent stability and superconductivity of NaKH12 originate from the fact that the localized electrons in the interstitial region of the metal lattice occupying the crystal orbitals well matched with the hydrogen lattice and forming chemical templates to assist the assembly of H2 units. These localized electrons weaken the H─H covalent bonds and improve the charge connectivity between the H2 units, ensuring the strong coupling between electrons and hydrogen-dominated optical phonons. The theory provides a key perspective for understanding the superconductivity of molecular hydrides with various structural motifs, opening the door to obtaining high-temperature superconductors from molecular hydrides at moderate pressures.","PeriodicalId":112,"journal":{"name":"Advanced Functional Materials","volume":"31 1","pages":""},"PeriodicalIF":19.0,"publicationDate":"2024-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142665345","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Highly Potent Os@Au-TPA Coordination Structure-Based Sonosensitizer for Tumor Sono-Immunotherapies 用于肿瘤超声免疫疗法的高效力 Os@Au-TPA 配位结构声敏化剂

IF 19 1区材料科学

Advanced Functional Materials Pub Date : 2024-11-18 DOI: 10.1002/adfm.202412564

Pengfei Xie, Xiao Rong, Xuelian Qin, Min Li, Yan Zuo, Bingjie Liu, Sujiao Cao, Jie Yang, Li Qiu

{"title":"A Highly Potent Os@Au-TPA Coordination Structure-Based Sonosensitizer for Tumor Sono-Immunotherapies","authors":"Pengfei Xie, Xiao Rong, Xuelian Qin, Min Li, Yan Zuo, Bingjie Liu, Sujiao Cao, Jie Yang, Li Qiu","doi":"10.1002/adfm.202412564","DOIUrl":"https://doi.org/10.1002/adfm.202412564","url":null,"abstract":"Ultrasound (US) becomes an appealing modality for stimulating or amplifying immune responses during cancer therapy, which is also termed sono-immunotherapy. However, the clinical prospect has not been fully realized due to the scarcity of efficient sonosensitizers. Herein, for the first time a novel Os-doped Au-tri(pyridin-4-yl) amine coordination structure (Os@Au-TPA)-based sonosensitizer is originally designed and synthesized for sono-immunotherapy of breast-metastasized tumors. Impressively, Os@Au-TPA shows much higher US-mediated 1O2-producing activity than Au-TPA as well as the other traditional sonosensitizers, for example, ≈41.6 folds to ce6, 19.5 times to Protoporphyrin IX (PpIX), 12.0 to Indocyanine Green (ICG), and 11.1 to Iron phthalocyanine (Pc(Fe)). The Os@Au-TPA can not only generate abundant ROS upon US irradiation to implement sonodynamic therapy (SDT), stimulating cell apoptosis and further immunogenic cell death, but can also generate O2 to alleviate hypoxia to promote the polarization of M2 to M1 macrophages to enhance tumor immunogenicity. As a result, when combined with PD-L1 antibody, it remodels the immunosuppressive tumor microenvironment, achieves concurrent sonodynamic-triggered immune activation, and eradicates both the original and distant-metastasized tumors efficiently. This work not only provides a new strategy to construct potent sonosensitizers from pyridine-metal coordination structures but also proves that sonosensitizers with high performance are crucial in boosting cancer sono-immunotherapy.","PeriodicalId":112,"journal":{"name":"Advanced Functional Materials","volume":"99 1","pages":""},"PeriodicalIF":19.0,"publicationDate":"2024-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142665387","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Enhanced Second-Harmonic Generation in Quadratically Nonlinear Weyl Semimetal NbAs for Broadband Photodetection Applications 增强四非线性韦尔半金属 NbAs 中的二次谐波生成，实现宽带光电探测应用

IF 19 1区材料科学

Advanced Functional Materials Pub Date : 2024-11-18 DOI: 10.1002/adfm.202418485

Xin Li, Yu Bian, Cong Xia, Bojin Zhao, Shihui Ma, Jiajia Wang, Hailong Qiu, Hongjun Liu, Ming Liu, Hongwei Yu, Ning Ye, Zhanggui Hu, Yicheng Wu

{"title":"Enhanced Second-Harmonic Generation in Quadratically Nonlinear Weyl Semimetal NbAs for Broadband Photodetection Applications","authors":"Xin Li, Yu Bian, Cong Xia, Bojin Zhao, Shihui Ma, Jiajia Wang, Hailong Qiu, Hongjun Liu, Ming Liu, Hongwei Yu, Ning Ye, Zhanggui Hu, Yicheng Wu","doi":"10.1002/adfm.202418485","DOIUrl":"https://doi.org/10.1002/adfm.202418485","url":null,"abstract":"Quadratically nonlinear photodetectors (QNPDs) typically focus on 2D materials with high second-order nonlinear polarizability, thereby severely disregarding bulk nonlinear optical (NLO) crystals as these rely on phase-matching technology and achieving efficient bulk QNPDs remains a significant challenge. Weyl semimetal crystals have some signatures of inversion symmetry breaking, most notably second-order NLO polarizability, while the inability to balance the low transmittance limits frequency conversion of the zero-band gap absorption-induced crystal. Herein, this study investigates an efficient QNPD based on bulk NbAs crystals designed with a strong second-harmonic effect due to its large refractive index (≈5.0), resulting in an intense laser reflectivity of 50% on its surface, which creates a favorable environment for achieving second-harmonic generation (SHG) without phase matching. The QNPD has a rectification ratio exceeding 107 with a dark current of 164 pA and an enhanced photoresponse in the 355‒1900 nm range, exhibiting a maximum responsivity of 4.1 mA W−1 with a detectivity of 0.8 × 1010 Jones at 355 nm. The responsivity improvement rate is 88% higher than that of linear NbAs (001) photodetector. This study opens new avenues for designing QNPDs by utilizing the second harmonic effect in bulk Weyl semimetal crystals.","PeriodicalId":112,"journal":{"name":"Advanced Functional Materials","volume":"18 1","pages":""},"PeriodicalIF":19.0,"publicationDate":"2024-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142670717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dual-Surface Polydentate Anchoring Enabled Strain Regulation for Stable and Efficient Perovskite Solar Cells 双表面多齿锚定实现应变调节，实现稳定高效的 Perovskite 太阳能电池

IF 19 1区材料科学

Advanced Functional Materials Pub Date : 2024-11-18 DOI: 10.1002/adfm.202415547

Fancong Zeng, Lin Xu, Chencheng Hu, Jiahe Xing, Yanjie Wu, Xue Bai, Biao Dong, Hongwei Song

{"title":"Dual-Surface Polydentate Anchoring Enabled Strain Regulation for Stable and Efficient Perovskite Solar Cells","authors":"Fancong Zeng, Lin Xu, Chencheng Hu, Jiahe Xing, Yanjie Wu, Xue Bai, Biao Dong, Hongwei Song","doi":"10.1002/adfm.202415547","DOIUrl":"https://doi.org/10.1002/adfm.202415547","url":null,"abstract":"Continuous breakthroughs of photoelectric conversion efficiency (PCE) in perovskite solar cells are achieved, but the inherent instability caused by residual tensile strain and interfacial defects remains a major obstacle to their application. In this study, a polydentate ligand-regulated dual-surface stress management strategy for perovskite (PVK) is introduced to eliminate tensile strain and interface defects via multidentate anchoring. 3-amino-5-bromopicolinaldehyde (BD) is employed on the lower surface of PVK, while its −CO, −NH2, and pyridine functional groups facilitate the bridging of SnO2 with PVK, alleviating tensile stress and lowering interfacial energy barriers. For the upper surface, the bis−SO2, pyridine, and bis−CF3 functional groups of N-(5-Chloro-2-pyridyl) bis(trifluoromethanesulfonimide) (FC) are utilized to increase the ion migration energy barrier through anchoring, which effectively diminishes tensile stress and defects. Besides, −CF3 also constructs a hydrophobic barrier on the upper surface. Notably, tensile stress successfully transforms into compressive stress based on the dual-surface stress regulation, significantly improving the framework stability of PVK. Consequently, the devices treated with BD and FC achieve an elevated open-circuit voltage of 1.24 V and PCE of 24.70%. The modified device (unencapsulated) maintains 92% of initial PCE after 2000 h in the atmosphere and 91% after 500 h under 85% RH, showcasing enhanced stability.","PeriodicalId":112,"journal":{"name":"Advanced Functional Materials","volume":"128 1","pages":""},"PeriodicalIF":19.0,"publicationDate":"2024-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142670773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

2D Memory Enabled by Electrical Stimulation-Induced Defect Engineering for Complicated Neuromorphic Computing 通过电刺激诱导缺陷工程实现二维存储器，用于复杂神经形态计算

IF 19 1区材料科学

Advanced Functional Materials Pub Date : 2024-11-18 DOI: 10.1002/adfm.202416333

Jie Cheng, Pan Zhang, Xinyu Ouyang, Weijia Tang, Bing Song, Youwei Zhang, Yu Zheng, Anlian Pan

{"title":"2D Memory Enabled by Electrical Stimulation-Induced Defect Engineering for Complicated Neuromorphic Computing","authors":"Jie Cheng, Pan Zhang, Xinyu Ouyang, Weijia Tang, Bing Song, Youwei Zhang, Yu Zheng, Anlian Pan","doi":"10.1002/adfm.202416333","DOIUrl":"https://doi.org/10.1002/adfm.202416333","url":null,"abstract":"Defect engineering is extensively utilized in 2D memory devices due to its effectiveness in enhancing charge-trapping ability. However, conventional defect modulation techniques usually introduce only single types of carrier traps and cannot reconfigure trap types and densities after device fabrication. Here, for the first time, electrical stimulation-driven long-range migration of Cu ions within CuInP2S6 (CIPS) films is demonstrated to simultaneously introduce both electron and hole traps and enable reconfigurable modulation of interfacial defect trapping. This process is referred to as “electrical stimulation-induced defect engineering”. By integrating these defect traps and the dual-gate coupling effect, the memory window-to-scan range (MW/S.R) ratio, which reflects the device's charge trapping ability, doubled and peaked at 78.1% at Vbg = ± 80 V. Additionally, the dual-gate memory device based on the graphene/CIPS/h-BN/WSe2 heterostructure exhibits a maximum on/off ratio reaching 107 for multi-level storage states, integrating neuromorphic computing and logic operations within a single platform. With 81 storage states and paired-pulse facilitation (PPF), it achieves ≈90% accuracy in reservoir computing (RC) simulations. These results highlight the potential of electrical stimulation-induced defect engineering for next-generation electronics.","PeriodicalId":112,"journal":{"name":"Advanced Functional Materials","volume":"18 1","pages":""},"PeriodicalIF":19.0,"publicationDate":"2024-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142670769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Aqu-Thermoplastics: Recycling Plastics with Water 水热塑料：用水回收塑料

IF 19 1区材料科学

Advanced Functional Materials Pub Date : 2024-11-18 DOI: 10.1002/adfm.202417119

Chunchun Yin, Yirong Wang, Jinfeng Wang, Jingxuan You, Xi Wang, Jun Zhang, Jinming Zhang

{"title":"Aqu-Thermoplastics: Recycling Plastics with Water","authors":"Chunchun Yin, Yirong Wang, Jinfeng Wang, Jingxuan You, Xi Wang, Jun Zhang, Jinming Zhang","doi":"10.1002/adfm.202417119","DOIUrl":"https://doi.org/10.1002/adfm.202417119","url":null,"abstract":"Recycling of real waste plastics with diverse composition is extremely difficult. Herein, an eco-friendly and easy-to-operate strategy is demonstrated to facilitate the recycling of plastic composites and mixtures by using only water. An aqu-thermoplastic bioplastic (CPp-TA) is constructed with switchable water solubility and excellent thermoplastic property from natural cellulose. CPp-TA consisted of the cellulose main chain (C) and two functional groups, internal-plasticizing group (Pp) and switchable group (TA). It not only has outstanding thermo-plastic formability, water resistance, and mechanical property to satisfy the daily needs, but also can be easily recycled with water by switching to the water-soluble state. CPp-TA can processed into various high-performance plastic parts, fibers, heat-sealing packaging, transparent cups, paper-plastic composites, and aluminum-plastic composites by conventional thermoplastic processing methods. The obtained CPp-TA/Al/paper composite exhibits better barrier performance than the famous Tetra Pak with a complex recycling process, and can be easily separated into CPp-TA, Al foil, and paper by using basic aqueous solution to trigger the water solubility of CPp-TA. Similarly, CPp-TA can be effectively separated from plastic mixtures. The recovery yield achieves to 100%. The revolutionary aqu-thermoplastic materials and water-recycling strategy markedly reduce the recycling difficulty of intricate plastics and promote the sustainable development.","PeriodicalId":112,"journal":{"name":"Advanced Functional Materials","volume":"99 1","pages":""},"PeriodicalIF":19.0,"publicationDate":"2024-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142670772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

High-Performance Organic Solar Cells Enabled by 3D Globally Aromatic Carboranyl Solid Additive 利用三维全球芳香族碳硼酰固体添加剂实现高性能有机太阳能电池

IF 19 1区材料科学

Advanced Functional Materials Pub Date : 2024-11-18 DOI: 10.1002/adfm.202418805

Hanqiang Wang, Zhicheng Zhong, Sergio Gámez-Valenzuela, Jin-Woo Lee, Bolin Li, Changjing Xu, Jie Yang, Huiliang Sun, Bumjoon J. Kim, Bin Liu, Xugang Guo

{"title":"High-Performance Organic Solar Cells Enabled by 3D Globally Aromatic Carboranyl Solid Additive","authors":"Hanqiang Wang, Zhicheng Zhong, Sergio Gámez-Valenzuela, Jin-Woo Lee, Bolin Li, Changjing Xu, Jie Yang, Huiliang Sun, Bumjoon J. Kim, Bin Liu, Xugang Guo","doi":"10.1002/adfm.202418805","DOIUrl":"https://doi.org/10.1002/adfm.202418805","url":null,"abstract":"A key factor in optimizing organic solar cells (OSCs) is the precise control of blend film morphology to enhance exciton dissociation and charge transport. Solid additives play a vital role in this process, with 3D polyhedral or spherical molecules being ideal candidates due to their delocalized π-orbitals and omnidirectional charge transport. However, the application of classical fullerene derivatives as spherical additives is limited by their synthetic complicacy and poor solubility. Herein, the potential of 3D globally aromatic carboranyl cages as solid additives, specifically 1-amino-o-carborane (CB-NH2) and 1-carboxy-o-carborane (CB-COOH), is explored to fine-tune the film morphology and improve the performance of OSCs. These spherical molecules provide an extensive surface for hydrogen bonding interactions, which serve as the driving force for manipulating the vertical phase separation and active layer crystallinity. Remarkably, CB-NH2-processed devices with well-tuned morphology yield a remarkable power conversion efficiency of 19.48%, highlighting the effectiveness of 3D carboranyl additives on improving OSC performance. This work challenges the reliance on fullerene derivatives as spherical additives and offers new insights into the mechanisms by which 3D globally aromatic additives can achieve high performance in OSCs, emphasizing the significance of molecular engineering in the development of next-generation solar cell technology.","PeriodicalId":112,"journal":{"name":"Advanced Functional Materials","volume":"34 1","pages":""},"PeriodicalIF":19.0,"publicationDate":"2024-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142670776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Chemically Processed Porous V2O5 Thin-Film Cathodes for High-Performance Thin-film Zn-Ion Batteries 用于高性能薄膜锌-离子电池的化学加工多孔 V2O5 薄膜阴极

IF 19 1区材料科学

Advanced Functional Materials Pub Date : 2024-11-18 DOI: 10.1002/adfm.202417607

Jingli Luo, Mengjue Cao, Nibagani Naresh, Jnanraj Borah, Shuhui Li, Tianlei Wang, Bimal K. Sarma, Jianfeng Yao, Ivan P. Parkin, Buddha Deka Boruah

{"title":"Chemically Processed Porous V2O5 Thin-Film Cathodes for High-Performance Thin-film Zn-Ion Batteries","authors":"Jingli Luo, Mengjue Cao, Nibagani Naresh, Jnanraj Borah, Shuhui Li, Tianlei Wang, Bimal K. Sarma, Jianfeng Yao, Ivan P. Parkin, Buddha Deka Boruah","doi":"10.1002/adfm.202417607","DOIUrl":"https://doi.org/10.1002/adfm.202417607","url":null,"abstract":"Thin-film rechargeable batteries have a wide range of applications due to their unique properties such as small size, thinness, and the ability to power smart devices, including portable electronic devices, medical devices, smart cards, RFID tags, and Internet of Things (IoT) devices. Processing thin-film electrodes for these batteries generally relies on standard physical vapor deposition technologies. However, producing porous thin-films using these techniques presents significant challenges. Here, a rapid and cost-effective chemical route for processing porous vanadium oxide (V2O5) thin-film cathodes for application in Zinc-ion-based thin-film batteries (Zn-TFBs) is explored. The V2O5 precursor process uses an industrially viable spraying technique, which not only offers impressive charge storage performance of an areal capacity of 47.34 µAh cm−2, areal energy of 50.18 µWh cm−2, and areal power of 53 µW cm−2 at 50 µA cm−2 in the optimized gel-electrolyte composition. This study introduces a cost-effective and industrially viable method for processing highly porous thin-film cathodes, enabling the production of high-performance, affordable, and safer thin-film batteries.","PeriodicalId":112,"journal":{"name":"Advanced Functional Materials","volume":"7 1","pages":""},"PeriodicalIF":19.0,"publicationDate":"2024-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142670770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Highly Efficient Blue Organic Light-Emitting Devices Based on “Cross”-Shaped Hot Exciton Emitters 基于 "十字 "形热激子发射器的高效蓝色有机发光器件

IF 19 1区材料科学

Advanced Functional Materials Pub Date : 2024-11-18 DOI: 10.1002/adfm.202415633

Chunyu Liu, Denghui Liu, Deli Li, Tong Wang, Di Liu, Xilin Mu, Jiasen Zhang, Tingting Feng, Kaibo Fang, Shi-Jian Su, Yubo Zhou, Siyao Wu, Wei Li, Ziyi Ge

{"title":"Highly Efficient Blue Organic Light-Emitting Devices Based on “Cross”-Shaped Hot Exciton Emitters","authors":"Chunyu Liu, Denghui Liu, Deli Li, Tong Wang, Di Liu, Xilin Mu, Jiasen Zhang, Tingting Feng, Kaibo Fang, Shi-Jian Su, Yubo Zhou, Siyao Wu, Wei Li, Ziyi Ge","doi":"10.1002/adfm.202415633","DOIUrl":"https://doi.org/10.1002/adfm.202415633","url":null,"abstract":"The development of blue electroluminescent (EL) materials remains a significant challenge in organic light-emitting diode (OLED) technology. In this study, a novel design strategy is proposed for blue hot exciton (HE) materials, which involves utilizing a “cross” shaped molecular structure characterized by substantial steric hindrance and a highly twisted conformation. The unique cross-shaped molecular architecture with distinct “arms” enables flexible control over the excited state properties of the molecule, thereby facilitating precise modulation of high-lying triplet and low-lying singlet excited state energy levels. Furthermore, the 3D spatial configuration of the molecule effectively reduces close molecular packing, thereby minimizing the risk of material concentration quenching. The proof-of-concept HE emitters CN-PI and TP-PI exhibit non-π-π stacking configurations in single crystals, achieving high photoluminescence quantum yield (PLQY) values up to 51.3% and 46.5% in non-doped thin films, respectively, along with rapid radiation decay rates and reasonable distribution of Tm (m ≤ 5) and S1 states. Non-doped OLEDs incorporating these emitters demonstrate exceptional external quantum efficiencies (EQE), reaching 7.3% and 6.4%, respectively, while exhibiting minimal efficiency roll-off at high luminance. This research introduces a promising approach for developing high-performance blue HE emitters.","PeriodicalId":112,"journal":{"name":"Advanced Functional Materials","volume":"248 1","pages":""},"PeriodicalIF":19.0,"publicationDate":"2024-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142665343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Biodegradable Acid-Responsive Nanocarrier for Enhanced Antibiotic Therapy Against Drug-Resistant Helicobacter Pylori via Urease Inhibition 可生物降解的酸响应纳米载体，通过抑制尿素酶加强抗生素治疗抗药性幽门螺旋杆菌的效果

IF 19 1区材料科学

Advanced Functional Materials Pub Date : 2024-11-18 DOI: 10.1002/adfm.202412893

Huizhen Fan, Ka Ioi Wong, Yingying Ma, Ming Li, Hanqing Li, Li Wei, Shen Wang, Min Yao, Min Lu

{"title":"Biodegradable Acid-Responsive Nanocarrier for Enhanced Antibiotic Therapy Against Drug-Resistant Helicobacter Pylori via Urease Inhibition","authors":"Huizhen Fan, Ka Ioi Wong, Yingying Ma, Ming Li, Hanqing Li, Li Wei, Shen Wang, Min Yao, Min Lu","doi":"10.1002/adfm.202412893","DOIUrl":"https://doi.org/10.1002/adfm.202412893","url":null,"abstract":"Metal ion-based inhibition of urease activity is a promising strategy for treating Helicobacter pylori (H. pylori) infections. However, the challenges of safe delivery and reducing cytotoxicity persist. In this study, an innovative nanocarrier capable of acid-responsive release of Ag+ and antibiotics is developed, with complete degradation after treatment. Mesoporous organosilica nanoparticle (MON) is encapsulated with hyaluronic acid (HA) to prevent drug leakage and further coated with bacterial outer membrane vesicle (OMV) from Escherichia coli Nissle 1917, creating a nanocarrier with cell-protective capabilities. Ag+ and antibiotic clarithromycin (CLR) are incorporated into the nanocarrier to form CLR-Ag+@MON@HA@OMV (CAMO), designed for the targeted treatment of gastric H. pylori infection. The HA encapsulation ensures acid-responsive release of CLR and Ag+ in the stomach, preventing premature release at non-inflammatory sites. There is a potential for Ag⁺ in CAMO to replace Ni2⁺ at the active site of urease, enhancing the bactericidal effect of CLR through urease inhibition. Furthermore, the OMV provides additional cytoprotection, mitigating cell damage and inflammation response induced by the H. pylori infection. This study introduces a safe and effective nanocarrier that eradicates H. pylori and alleviates gastric inflammation.","PeriodicalId":112,"journal":{"name":"Advanced Functional Materials","volume":"48 1","pages":""},"PeriodicalIF":19.0,"publicationDate":"2024-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142665388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0