Diseases of the Colon & Rectum最新文献

{"title":"Being Artificially Intelligent.","authors":"James Church","doi":"10.1097/DCR.0000000000004302","DOIUrl":"10.1097/DCR.0000000000004302","url":null,"abstract":"","PeriodicalId":11299,"journal":{"name":"Diseases of the Colon & Rectum","volume":" ","pages":"2223-2225"},"PeriodicalIF":3.1,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148162209","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Response to: CRC Screening, A Long Way Off.","authors":"Anyelin Almanzar, Sophia Dahmani, Sami Shoucair","doi":"10.1097/DCR.0000000000003569","DOIUrl":"10.1097/DCR.0000000000003569","url":null,"abstract":"","PeriodicalId":11299,"journal":{"name":"Diseases of the Colon & Rectum","volume":" ","pages":"2357"},"PeriodicalIF":3.1,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142497003","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"From Primary Care Attachment to Continuity of Survivorship Care After Proctectomy: Nursing-Sensitive Targets to Reduce Emergency Department Utilization.","authors":"Hui Zang, Zubing Mei","doi":"10.1097/DCR.0000000000004296","DOIUrl":"10.1097/DCR.0000000000004296","url":null,"abstract":"","PeriodicalId":11299,"journal":{"name":"Diseases of the Colon & Rectum","volume":" ","pages":"2350-2351"},"PeriodicalIF":3.1,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148013708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Postoperative Recurrence in Crohn's Disease: The Ongoing Challenge of Risk Stratification.","authors":"İbrahim Ethem Güven","doi":"10.1097/DCR.0000000000004294","DOIUrl":"10.1097/DCR.0000000000004294","url":null,"abstract":"","PeriodicalId":11299,"journal":{"name":"Diseases of the Colon & Rectum","volume":" ","pages":"2347"},"PeriodicalIF":3.1,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147981069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cost-Effectiveness of Pelvic Floor Reconstruction Using Biological Mesh After Extralevator Abdominoperineal Resection for Rectal Cancer.","authors":"Rudolf van den Berg, Gijsbert D Musters, Cornelis Verhoef, Sarah Sharabiany, Roel Hompes, Baljit Singh, Sanjay S Chaudhri, Anna A W van Geloven, Ronald J C L M Vuylsteke, Johannes H W de Wilt, Jeroen W A Leijtens, Maarten Vermaas, Joost Rothbarth, Jacobus W A Burger, Bas Lamme, Anthony van de Ven, Hedwig M Blommestein, Pieter J Tanis","doi":"10.1097/DCR.0000000000004326","DOIUrl":"10.1097/DCR.0000000000004326","url":null,"abstract":"<p><strong>Background: </strong>Perineal complications are a major source of morbidity after extralevator abdominoperineal resection for low rectal cancer, especially after neoadjuvant (chemo)radiotherapy. Biological mesh reconstruction can reduce perineal hernia formation, but its cost-effectiveness remains unclear.</p><p><strong>Objective: </strong>To evaluate the cost-effectiveness of biological mesh reconstruction compared with primary perineal closure after extralevator abdominoperineal resection in patients with low rectal cancer.</p><p><strong>Design: </strong>This study was designed as a long-term economic evaluation conducted alongside a multicenter, parallel-group, randomized controlled trial.</p><p><strong>Settings: </strong>Eleven hospitals in the Netherlands and 1 hospital in the United Kingdom, including nonteaching, teaching, and university centers.</p><p><strong>Patients: </strong>Adult patients with primary low rectal cancer were enrolled in the study.</p><p><strong>Interventions: </strong>Primary layered perineal closure versus pelvic floor reconstruction using a biological, non-cross-linked porcine dermal mesh.</p><p><strong>Main outcome measures: </strong>Total health care costs from a health care payer perspective, incorporating surgery, hospitalization, outpatient care, wound management, readmissions, and reinterventions; and patient health outcomes measured as quality-adjusted life years calculated from standardized health utility scores.</p><p><strong>Results: </strong>Of 104 randomly assigned patients, 101 were included in the final analysis (53 primary closures, 48 biological mesh). Mean total health care costs were higher in the mesh group (€57,991 vs €56,232; mean difference €1571; 95% CI, -€9840 to €12,981; p  = 0.785). Perineal complications significantly reduced quality of life, but wound complication rates and quality-of-life gains were modest for mesh, with no significant differences between groups over time.</p><p><strong>Limitations: </strong>The study sample size limited the precision of cost and subgroup estimates.</p><p><strong>Conclusions: </strong>Biological mesh reconstruction increases procedural and hospitalization costs without improving long-term patient outcomes. Routine use cannot be recommended from a cost-effectiveness perspective. See Video Abstract .</p><p><strong>Costoefectividad de la reconstruccin del suelo plvico mediante malla biolgica tras la reseccin abdominoperineal extralevadora para el cncer rectal: </strong>ANTECEDENTES:Las complicaciones perineales constituyen una fuente importante de morbilidad tras la resección abdominoperineal extralevadora para el cáncer de recto bajo, especialmente después de recibir (quimio)radioterapia neoadyuvante. La reconstrucción con malla biológica puede reducir la formación de hernias perineales, pero su rentabilidad sigue sin estar clara.OBJETIVO:Evaluar la rentabilidad de la reconstrucción con malla biológica en comparación con el cierre perineal primar","PeriodicalId":11299,"journal":{"name":"Diseases of the Colon & Rectum","volume":" ","pages":"2312-2320"},"PeriodicalIF":3.1,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13465701/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148249767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"September 2026 Translations.","authors":"","doi":"10.1097/DCR.0000000000004390","DOIUrl":"https://doi.org/10.1097/DCR.0000000000004390","url":null,"abstract":"","PeriodicalId":11299,"journal":{"name":"Diseases of the Colon & Rectum","volume":"69 9","pages":"2358-2395"},"PeriodicalIF":3.1,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148879602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"How Much Does It Cost to Become a Colorectal Surgeon? A Cost Comparison of Training in the United States, Australia and New Zealand, and the United Kingdom.","authors":"Cameron P Douglas, Kilian G M Brown, Paolo Goffredo, Paul A Sutton, Cameron I Law","doi":"10.1097/DCR.0000000000004168","DOIUrl":"10.1097/DCR.0000000000004168","url":null,"abstract":"","PeriodicalId":11299,"journal":{"name":"Diseases of the Colon & Rectum","volume":" ","pages":"2226-2229"},"PeriodicalIF":3.1,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147873712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Achieving Stoma-Free Status After Intersphincteric Resection Remains a Long and Challenging Journey.","authors":"Songtao Bai, Bo Liu, Song Zhao","doi":"10.1097/DCR.0000000000004298","DOIUrl":"10.1097/DCR.0000000000004298","url":null,"abstract":"","PeriodicalId":11299,"journal":{"name":"Diseases of the Colon & Rectum","volume":" ","pages":"2353"},"PeriodicalIF":3.1,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148013744","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comment on \"Neoadjuvant Chemotherapy Versus Chemoradiation for Locally Advanced Rectal Cancer: A Multicenter Propensity Score-Matched Study\".","authors":"Obafemi K Wuraola, Constantine Ezeme, Pratik Bhattacharya, Giordano Perin","doi":"10.1097/DCR.0000000000004292","DOIUrl":"10.1097/DCR.0000000000004292","url":null,"abstract":"","PeriodicalId":11299,"journal":{"name":"Diseases of the Colon & Rectum","volume":" ","pages":"2345"},"PeriodicalIF":3.1,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147981074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk Factors for Small-Bowel Crohn's Disease Recurrence After Total Proctocolectomy.","authors":"Maxwell D Mirande, Ana Sofia Ore, Emily G Flaherty, Ian S Reynolds, Ahmed A Alaoui, Danilo Tueme de la Pena, Matas Jakubauskas, Nitin Mishra, Luca Stocchi, William R G Perry, Kellie L Mathis, Nicholas P McKenna","doi":"10.1097/DCR.0000000000004329","DOIUrl":"10.1097/DCR.0000000000004329","url":null,"abstract":"<p><strong>Background: </strong>Surgical management of Crohn's disease of the colon and rectum frequently requires total proctocolectomy with end ileostomy. There are limited data on the need for Crohn's disease-directed therapy and the prevalence of recurrence after surgery.</p><p><strong>Objective: </strong>To determine the risk of small-bowel Crohn's disease recurrence and evaluate risk factors for postoperative recurrence after total proctocolectomy with end ileostomy.</p><p><strong>Design: </strong>Retrospective cohort study.</p><p><strong>Settings: </strong>Multistate tertiary health care system.</p><p><strong>Patients: </strong>Adult patients with Crohn's disease undergoing total proctocolectomy with end ileostomy between 2014 and 2023.</p><p><strong>Main outcome measures: </strong>The primary outcome was small-bowel Crohn's disease recurrence.</p><p><strong>Results: </strong>A total of 193 patients with a median age of 45 years (interquartile range, 34-61) were included. More than half of the patients (n = 102; 52.9%) had a history of small-bowel Crohn's disease, and the majority (n = 134; 69.4%) received biologic therapy before surgery. The median follow-up time was 4.8 years (interquartile range, 2.0-7.6). Postoperatively, 30.6% of patients (n = 59) received biologic therapy. Thirty-five patients (18.1%) had small-bowel Crohn's disease recurrence for an estimated 5-year recurrence-free rate of 80.2% (95% CI, 73.0-85.7). Seven patients (3.6%) developed small-bowel Crohn's disease recurrence requiring surgery for an estimated 5-year surgical recurrence-free rate of 94.7% (95% CI, 89.0-97.5). On multivariable analysis, history of small-bowel Crohn's disease (HR 2.17; 95% CI' 1.04-4.54) and diagnosis at age younger than 18 years (HR 2.31; 95% CI'1.1-4.86) were associated with small-bowel Crohn's disease recurrence.</p><p><strong>Limitations: </strong>Retrospective design and nonstandardized follow-up.</p><p><strong>Conclusions: </strong>Patients undergoing total proctocolectomy with end ileostomy for Crohn's disease have approximately a 20% risk of small-bowel recurrence at 5 years but a low risk of requiring surgical intervention. Patients with a history of small-bowel Crohn's disease and younger age at diagnosis have a higher risk of recurrence and may warrant consideration of more frequent surveillance and medical prophylaxis. See Video Abstract .</p><p><strong>Factores de riesgo de recurrencia de la enfermedad de crohn del intestino delgado despus de una proctocolectoma total: </strong>ANTECEDENTES:El tratamiento quirúrgico de la enfermedad de Crohn del colon y el recto frecuentemente requiere proctocolectomía total con ileostomía terminal. Existe información limitada sobre la necesidad de terapia dirigida a la enfermedad de Crohn y la prevalencia de recurrencia tras la cirugía.OBJETIVO:Determinar el riesgo de recurrencia de la enfermedad de Crohn del intestino delgado y evaluar los factores de riesgo de recurrencia posoperatoria tras p","PeriodicalId":11299,"journal":{"name":"Diseases of the Colon & Rectum","volume":" ","pages":"2266-2272"},"PeriodicalIF":3.1,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148224145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}