Digestive and Liver Disease最新文献

{"title":"Author's reply: Claudin-2 immunochemistry in IBD","authors":"Vincenzo Villanacci , Rachele Del Sordo , Gabrio Bassotti","doi":"10.1016/j.dld.2025.05.022","DOIUrl":"10.1016/j.dld.2025.05.022","url":null,"abstract":"","PeriodicalId":11268,"journal":{"name":"Digestive and Liver Disease","volume":"57 8","pages":"Page 1707"},"PeriodicalIF":4.0,"publicationDate":"2025-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144246891","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Personalized bevacizumab dosing in metastatic colorectal cancer: Statistical considerations for a phase III randomized trial.","authors":"Yue Lv, Jiaying Yu, Wei Ye","doi":"10.1016/j.dld.2025.05.009","DOIUrl":"https://doi.org/10.1016/j.dld.2025.05.009","url":null,"abstract":"","PeriodicalId":11268,"journal":{"name":"Digestive and Liver Disease","volume":" ","pages":""},"PeriodicalIF":4.0,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144246895","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Author's reply: “Prevalence and outcomes of arthritis in pediatric IBD: A study from the Italian Society of Pediatric Gastroenterology Hepatology and Nutrition”","authors":"Saverio Pochesci , Luca Scarallo , Paolo Lionetti","doi":"10.1016/j.dld.2025.05.003","DOIUrl":"10.1016/j.dld.2025.05.003","url":null,"abstract":"","PeriodicalId":11268,"journal":{"name":"Digestive and Liver Disease","volume":"57 7","pages":"Page 1519"},"PeriodicalIF":4.0,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144246890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multiparametric magnetic resonance imaging may improve detection of patients with at-risk MASH: Real world experience in hepatology clinics","authors":"Meaghan M. Phipps ,&nbsp;Tatiana Hage ,&nbsp;Emily Truong ,&nbsp;Ju Dong Yang ,&nbsp;Lauren Nicolosi ,&nbsp;Andrea Dennis ,&nbsp;Elizabeth Shumbayawonda ,&nbsp;Prashant Pandya ,&nbsp;Julia Wattacheril","doi":"10.1016/j.dld.2025.05.023","DOIUrl":"10.1016/j.dld.2025.05.023","url":null,"abstract":"<div><h3>Background</h3><div>Early identification of patients with metabolic dysfunction-associated steatotic liver disease (MASLD) at risk for metabolic dysfunction-associated steatohepatitis (MASH) and/or advanced fibrosis (AF) can prevent disease progression. Non-invasive tests are useful to help identify at-risk patients. Current guidelines recommend primarily using the Fibrosis-4 (FIB-4) score for risk stratification. We aimed to evaluate the potential benefits of utilizing multiparametric magnetic resonance (mpMR) imaging to improve the detection of patients with at-risk MASLD.</div></div><div><h3>Methods</h3><div>In a prospective multicenter observational study, patients with MASLD who received mpMR as part of standard clinical care were included. Patient demographics and clinical, laboratory, and imaging data were extracted. Comparisons were made between the current guidelines for patients with suspected or established MASLD based on initial FIB-4 and risk stratification with mpMR. A cT1 of ≥800 ms was considered an indicator of high risk for progression.</div></div><div><h3>Results</h3><div>Of 102 patients with MASLD at two large academic centers, 77 % had low FIB-4 (&lt;1.3 for ≤65, and &lt;2 for &gt;65). 58 % of patients with low FIB-4 had cT1 ≥800 ms, indicating increased risk for MASH (63.5 % in ≤65, 48.1 % in &gt;65). Among those ≤65, those with cT1 ≥800 ms were more likely to be women (63.6 % v. 36.4 %, <em>p</em> &lt; 0.01) and had higher rates of diabetes (30.3 % v. 5.3 %, <em>p</em> = 0.03). Dyslipidemia was common (65 % of patients), but only 51.5 % were on lipid-lowering therapy.</div></div><div><h3>Conclusion</h3><div>In this real-world application of mpMR, over half of patients stratified as low risk by FIB-4 had cT1 suggesting increased risk for developing MASH or AF. Incorporation of mpMR earlier in the algorithm for patients with suspected or established MASLD may improve the identification of those with at-risk disease, allowing for earlier intervention to prevent progression and complications.</div></div>","PeriodicalId":11268,"journal":{"name":"Digestive and Liver Disease","volume":"57 8","pages":"Pages 1646-1653"},"PeriodicalIF":4.0,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144246894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vascular complications in inflammatory bowel disease: moving from recognition to personalised prevention","authors":"Wenbin Dai","doi":"10.1016/j.dld.2025.05.013","DOIUrl":"10.1016/j.dld.2025.05.013","url":null,"abstract":"","PeriodicalId":11268,"journal":{"name":"Digestive and Liver Disease","volume":"57 8","pages":"Pages 1702-1703"},"PeriodicalIF":4.0,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144246897","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Methodological considerations in evaluating the association between combined oral contraceptives and gastroparesis.","authors":"Yi Ding, Shuying Wang","doi":"10.1016/j.dld.2025.05.015","DOIUrl":"https://doi.org/10.1016/j.dld.2025.05.015","url":null,"abstract":"","PeriodicalId":11268,"journal":{"name":"Digestive and Liver Disease","volume":" ","pages":""},"PeriodicalIF":4.0,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144233422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Erratum regarding updated pagination in previously published articles","authors":"","doi":"10.1016/j.dld.2025.05.017","DOIUrl":"10.1016/j.dld.2025.05.017","url":null,"abstract":"","PeriodicalId":11268,"journal":{"name":"Digestive and Liver Disease","volume":"57 6","pages":"Pages 1362-1363"},"PeriodicalIF":4.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144189446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Full Title Page /Editorial Board","authors":"","doi":"10.1016/S1590-8658(25)00763-7","DOIUrl":"10.1016/S1590-8658(25)00763-7","url":null,"abstract":"","PeriodicalId":11268,"journal":{"name":"Digestive and Liver Disease","volume":"57 6","pages":"Pages i-ii"},"PeriodicalIF":4.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144190017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pancreatic fat density and post-ERCP pancreatitis: A complex relationship or a novel predictor?","authors":"Amir Farah ,&nbsp;Amir Mari","doi":"10.1016/j.dld.2025.02.019","DOIUrl":"10.1016/j.dld.2025.02.019","url":null,"abstract":"","PeriodicalId":11268,"journal":{"name":"Digestive and Liver Disease","volume":"57 6","pages":"Pages 1352-1353"},"PeriodicalIF":4.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143613939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Erratum to “A comprehensive RCT in screening, surveillance, and diagnostic AI-assisted colonoscopies (ACCENDO-Colo study)” [Digestive and Liver Disease 57 (2025) 762-9]","authors":"Cristiano Spada ,&nbsp;Daniele Salvi ,&nbsp;Clarissa Ferrari ,&nbsp;Cesare Hassan ,&nbsp;Federico Barbaro ,&nbsp;Nicoletta Belluardo ,&nbsp;Leonardo Minelli Grazioli ,&nbsp;Sebastian Manuel Milluzzo ,&nbsp;Nicola Olivari ,&nbsp;Luigi Giovanni Papparella ,&nbsp;Silvia Pecere ,&nbsp;Eugenia Vittoria Pesatori ,&nbsp;Lucio Petruzziello ,&nbsp;Stefania Piccirelli ,&nbsp;Alessandro Quadarella ,&nbsp;Paola Cesaro ,&nbsp;Guido Costamagna","doi":"10.1016/j.dld.2025.02.029","DOIUrl":"10.1016/j.dld.2025.02.029","url":null,"abstract":"","PeriodicalId":11268,"journal":{"name":"Digestive and Liver Disease","volume":"57 6","pages":"Page 1361"},"PeriodicalIF":4.0,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143691081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}