Current topics in behavioral neurosciences最新文献_第8页

Exercise and Protection from Age-Related Cognitive Decline. 运动与防止老年性认知功能衰退

Current topics in behavioral neurosciences Pub Date : 2024-01-01 DOI: 10.1007/7854_2024_501

J Carson Smith, Daniel D Callow, Gabriel S Pena, Yash Kommula, Naomi Arnold-Nedimala, Junyeon Won, Kristy A Nielson

引用次数: 0

Influence of Regular Physical Activity on Sleep. 有规律的体育锻炼对睡眠的影响

Current topics in behavioral neurosciences Pub Date : 2024-01-01 DOI: 10.1007/7854_2024_503

Melissa J McGranahan, Patrick J O'Connor

{"title":"Influence of Regular Physical Activity on Sleep.","authors":"Melissa J McGranahan, Patrick J O'Connor","doi":"10.1007/7854_2024_503","DOIUrl":"10.1007/7854_2024_503","url":null,"abstract":"Good sleep and adequate physical activity are essential to health. Yet, large numbers of people are chronically deficient in sleep and physical activity. About 1 in 3 Americans get less than 7 h of sleep per night and only 1 of 4 adults regularly complete weekly physical activity in amounts recommended for good health. This chapter reviews research that has examined relationships between regular physical activity and sleep. The overall weight of evidence supports that regular physical activity is associated with better sleep quality among healthy adults, with epidemiological studies showing moderate-sized effects and more well-controlled randomized controlled trial experiments often showing larger effects. Large epidemiology studies suggest that the relationship between regular physical activity and better sleep quality may partially mediate the well-established associations between physical activity and reduced risk of mortality, cardiovascular diseases, and dementia. There is evidence that the completion of regular physical activity also is associated with better sleep quality among those with certain sleep disorders (i.e., insomnia, obstructive sleep apnea, and restless legs syndrome), mental health disorders (i.e., depression and posttraumatic stress disorder), and medical illnesses (i.e., breast cancer survivors). The evidence is inadequate to support that regular physical activity substantially improves sleep quality either (i) in children, adolescents, and older adults, (ii) in those with cancers except for breast cancer, (iii) in those with fibromyalgia, or (iv) among those with chronic kidney disease. Also, there is inadequate evidence to conclude that sleep quality is disrupted during weeks when competitive athletes engage in periods of overtraining.","PeriodicalId":11257,"journal":{"name":"Current topics in behavioral neurosciences","volume":" ","pages":"309-328"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141855125","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Aging Brain from a Lifespan Perspective. 从生命周期的角度看大脑老化。

Current topics in behavioral neurosciences Pub Date : 2024-01-01 DOI: 10.1007/7854_2024_476

Anders Martin Fjell

{"title":"Aging Brain from a Lifespan Perspective.","authors":"Anders Martin Fjell","doi":"10.1007/7854_2024_476","DOIUrl":"10.1007/7854_2024_476","url":null,"abstract":"Research during the last two decades has shown that the brain undergoes continuous changes throughout life, with substantial heterogeneity in age trajectories between regions. Especially, temporal and prefrontal cortices show large changes, and these correlate modestly with changes in the corresponding cognitive abilities such as episodic memory and executive function. Changes seen in normal aging overlap with changes seen in neurodegenerative conditions such as Alzheimer's disease; differences between what reflects normal aging vs. a disease-related change are often blurry. This calls for a dimensional view on cognitive decline in aging, where clear-cut distinctions between normality and pathology cannot be always drawn. Although much progress has been made in describing typical patterns of age-related changes in the brain, identifying risk and protective factors, and mapping cognitive correlates, there are still limits to our knowledge that should be addressed by future research. We need more longitudinal studies following the same participants over longer time intervals with cognitive testing and brain imaging, and an increased focus on the representativeness vs. selection bias in neuroimaging research of aging.","PeriodicalId":11257,"journal":{"name":"Current topics in behavioral neurosciences","volume":" ","pages":"349-370"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141155125","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Physical Activity and Fatigue Symptoms: Neurotypical Adults and People with Chronic Multisymptom Illnesses. 体育活动与疲劳症状：神经畸形成人与慢性多症状疾病患者》（Neurotypical Adults and People with Chronic Multisymptom Illnesses）。

Current topics in behavioral neurosciences Pub Date : 2024-01-01 DOI: 10.1007/7854_2024_502

Alex Boruch, Grace Branchaw, Patrick J O'Connor, Dane B Cook

{"title":"Physical Activity and Fatigue Symptoms: Neurotypical Adults and People with Chronic Multisymptom Illnesses.","authors":"Alex Boruch, Grace Branchaw, Patrick J O'Connor, Dane B Cook","doi":"10.1007/7854_2024_502","DOIUrl":"10.1007/7854_2024_502","url":null,"abstract":"For neurotypical adults, a single bout of low-to-moderate intensity physical activity usually transiently improves feelings of energy. Similar bouts of exercise have the opposite effect of increased feelings of fatigue when performed by samples with chronic multisymptom illnesses (CMIs) such as Long-COVID, Gulf War Illness (GWI), or Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). The short-term adoption of regular moderate intensity physical activity (typical experiments are 1 to 6 months) among neurotypical adults results in small-to-moderate improvements in self-reported feelings of fatigue, energy, and vitality. Small improvements in these feelings, or no change at all, occur for CMIs, but limited data precludes strong conclusions. The mechanisms of exercise effects on fatigue, whether acute or chronic, are poorly understood but likely involve multiple neural circuits and associated transmitters. For CMIs, the mechanisms of acute worsening of fatigue with exercise may be driven by the yet unknown pathophysiological mechanisms of the disease (perhaps involving brain, immune and autonomic system dysfunction, and their interactions). Likewise, fatigue improvements may depend on whether chronic physical activity is a disease-modifying treatment.","PeriodicalId":11257,"journal":{"name":"Current topics in behavioral neurosciences","volume":" ","pages":"281-308"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141733778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Foundations of Exercise and Physical Activity Research. 运动和体育活动研究基础》。

Current topics in behavioral neurosciences Pub Date : 2024-01-01 DOI: 10.1007/7854_2024_488

Angelique G Brellenthin, Zoe Sirotiak

引用次数: 0

Area-level Measures of the Social Environment: Operationalization, Pitfalls, and Ways Forward. 社会环境的地区级衡量标准：操作、陷阱和前进方向。

Current topics in behavioral neurosciences Pub Date : 2024-01-01 DOI: 10.1007/7854_2024_464

Marco Helbich, Yi Zeng, Abeed Sarker

引用次数: 0

SSRIs in the Treatment of Depression: A Pharmacological CUL-DE-SAC? SSRIs治疗抑郁症：药理学CUL-DE-SAC？

Current topics in behavioral neurosciences Pub Date : 2024-01-01 DOI: 10.1007/7854_2023_447

Philip J Cowen

{"title":"SSRIs in the Treatment of Depression: A Pharmacological CUL-DE-SAC?","authors":"Philip J Cowen","doi":"10.1007/7854_2023_447","DOIUrl":"10.1007/7854_2023_447","url":null,"abstract":"The widespread adoption of selective serotonin reuptake inhibitors (SSRIs) as first-line pharmacological treatments in the management of clinical depression transformed the landscape of drug therapy for this condition. SSRIs are safer and better tolerated than the tricyclic antidepressants (TCAs) that they replaced. However, they have limitations that may have placed a ceiling on the expectations of first-line pharmacological treatment. Notable problems with SSRIs include induction of anxiety on treatment initiation, delayed onset of significant therapeutic effect, sexual dysfunction, sleep disturbance and overall modest efficacy. The latter is linked with an inability of SSRIs to effectively treat syndromes of anhedonia and cognitive impairment. Combined serotonin and noradrenaline reuptake inhibitors (SNRIs), such as venlafaxine, have produced some limited improvements over SSRIs in efficacy, at the cost of a greater side-effect burden. Attempts to supplement serotonin reuptake activity with actions at serotonin receptor sub-types have not yet yielded substantial benefits; however, vortioxetine may provide more utility in the management of cognitive impairment. Future advances might come from the development of SNRIs, which more closely mimic the actions of effective TCAs. There may also be possible benefits to be derived from combining SSRIs with 5-HT4 receptor agonists and 5-HT7 receptor antagonists.","PeriodicalId":11257,"journal":{"name":"Current topics in behavioral neurosciences","volume":" ","pages":"1-19"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71433973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Development and Maturation of the Human Brain, from Infancy to Adolescence. 人类大脑从婴儿期到青春期的发育和成熟。

Current topics in behavioral neurosciences Pub Date : 2024-01-01 DOI: 10.1007/7854_2024_514

Tomáš Paus

引用次数: 0

Correction to: Area-level Measures of the Social Environment: Operationalization, Pitfalls, and Ways Forward. 更正：社会环境的地区级衡量标准：操作、陷阱和前进方向。

Current topics in behavioral neurosciences Pub Date : 2024-01-01 DOI: 10.1007/7854_2024_481

Marco Helbich, Yi Zeng, Abeed Sarker

引用次数: 0

Psilocybin and Other Classic Psychedelics in Depression. 裸盖菇素和其他经典致幻剂治疗抑郁症。

Current topics in behavioral neurosciences Pub Date : 2024-01-01 DOI: 10.1007/7854_2023_451

D J Nutt, J M Peill, B Weiss, K Godfrey, R L Carhart-Harris, D Erritzoe

{"title":"Psilocybin and Other Classic Psychedelics in Depression.","authors":"D J Nutt, J M Peill, B Weiss, K Godfrey, R L Carhart-Harris, D Erritzoe","doi":"10.1007/7854_2023_451","DOIUrl":"10.1007/7854_2023_451","url":null,"abstract":"Psychedelic drugs such as psilocybin and ketamine are returning to clinical research and intervention across several disorders including the treatment of depression. This chapter focusses on psychedelics that specifically target the 5-HT2A receptor such as psilocybin and DMT. These produce plasma-concentration related psychological effects such as hallucinations and out of body experiences, insightful and emotional breakthroughs as well as mystical-type experiences. When coupled with psychological support, effects can produce a rapid improvement in mood among people with depression that can last for months. In this chapter, we summarise the scientific studies to date that explore the use of psychedelics in depressed individuals, highlighting key clinical, psychological and neuroimaging features of psychedelics that may account for their therapeutic effects. These include alterations in brain entropy that disrupt fixed negative ruminations, a period of post-treatment increased cognitive flexibility, and changes in self-referential psychological processes. Finally, we propose that the brain mechanisms underlying the therapeutic effect of serotonergic psychedelics might be distinct from those underlying classical serotonin reuptake-blocking antidepressants.","PeriodicalId":11257,"journal":{"name":"Current topics in behavioral neurosciences","volume":" ","pages":"149-174"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89717344","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0