Diabetic Medicine最新文献

{"title":"Evaluation of a secondary care multidisciplinary clinic for adults with early-onset type 2 diabetes at high risk in Leicester, Leicestershire and Rutland","authors":"Jonathan Goldney,&nbsp;Malak Hamza,&nbsp;Priscilla Sarkar,&nbsp;Harriet Morgan,&nbsp;Nicole Green,&nbsp;James Ridgeway,&nbsp;Victoria Alabraba,&nbsp;Laura Willcocks,&nbsp;Krupali Chandracant,&nbsp;Kashmala Javed,&nbsp;Rhys O'Callaghan,&nbsp;Finley Turner,&nbsp;Samuel Seidu,&nbsp;Claire L. Meek,&nbsp;Melanie J. Davies","doi":"10.1111/dme.70347","DOIUrl":"10.1111/dme.70347","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Clinical services for adults with early-onset type 2 diabetes (EOT2D) are in urgent need of improvement.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>We evaluated a multi-disciplinary clinic for individuals with EOT2D at high risk (HbA1c &gt;9%/triglyceride &gt;20 mmol/L), providing 2–3 flexibly arranged consultations per individual between March 2024 and September 2025. Nurse-led case-finding in primary care supported identification and targeted referral of high-risk individuals.</p>\u0000 \u0000 <p>On 3 November 2025, electronic medical records were used to evaluate change in cardiometabolic outcomes at 6- and 12-months from baseline and evaluate service activity, including proportions with recorded health information and prescriptions. The paired <i>t</i>-test (continuous) and McNemar's test (proportions) were used to assess change in outcomes. Patient feedback was obtained using questionnaires.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>In total, 159 individuals received an appointment (45% women; median age 34 years). At both 6- and 12-months post-baseline, HbA1c (at 12-months: −2.53% [95% CI: −3.13, −1.93]/−28 mmol/mol [−34, 21]), systolic (−5.89 mmHg [−9.88, −1.91]) and diastolic (−2.72 mmHg [−5.34, −0.10]) blood pressure, body mass index (BMI; −1.49 kg/m² [−2.31, −0.67]) and weight (−3.52 kg [−6.32, −0.72]) were significantly lower. Triglycerides were lower at 12-months only (−1.12 mmol/L [−1.89, −0.34]). The proportion with BMI or smoking status recorded, and with a glucagon-like peptide-1 receptor-based treatment, was higher at 12-months than at baseline, whereas creatinine and retinal screening measurements were less frequent. A limited amount of patient feedback was positive.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Discussion</h3>\u0000 \u0000 <p>Case-finding and invitation to flexibly run multidisciplinary clinics were associated with improvements in cardiometabolic outcomes and positive patient feedback. Similar services are immediately required given the rising prevalence of EOT2D and associated complications.</p>\u0000 </section>\u0000 </div>","PeriodicalId":11251,"journal":{"name":"Diabetic Medicine","volume":"43 11","pages":""},"PeriodicalIF":3.3,"publicationDate":"2026-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/dme.70347","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147795118","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A qualitative enquiry into the lived experiences of women with type 1 diabetes using closed-loop insulin delivery in pregnancy in the CIRCUIT trial","authors":"J. Hirtle,&nbsp;N. Goraya,&nbsp;A. Dunlop,&nbsp;J. Booth,&nbsp;D. S. Feig,&nbsp;J. Yamamoto,&nbsp;L. E. Donovan,&nbsp;K. H. Chaput,&nbsp;For the CIRCUIT Collaborative Group","doi":"10.1111/dme.70388","DOIUrl":"10.1111/dme.70388","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aims</h3>\u0000 \u0000 <p>This qualitative inquiry aimed to explore the lived experiences of pregnant women with self-management of type 1 diabetes (T1D) using closed-loop insulin delivery in the CIRCUIT trial⁹ to provide a qualitative overview of its impacts and improve the understanding of T1D experiences in pregnancy.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>We used semi-structured, individual interviews with 18 CIRCUIT randomized trial participants. Two team members analysed verbatim transcripts using inductive thematic analysis.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Four major themes emerged: 1. Independence and isolation; 2. Support is key; 3. Closed-loop impacts; and 4. Control and autonomy. Diabetes management during pregnancy was an emotionally overwhelming experience that was managed largely independently. Closed-loop was noted as a gamechanger for diabetes management during and after pregnancy. Participants felt the transition to and use of this technology would not have been possible without their healthcare team's support. Permeating all themes was the importance of control to achieve the best possible glycaemic outcomes for the health of their babies and autonomy over personal treatment decisions. The perceptions of loss of personal autonomy were associated with high anxiety.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Managing T1D while pregnant is an independent and isolating endeavour, due to the ‘invisible labour’ involved and the lack of knowledge about T1D management in personal networks. Support from partners and care providers alleviated stress. Experiences with intrapartum care providers who had limited T1D understanding were perceived as a challenge by some for maintaining autonomy. The closed-loop system was seen as a ‘gamechanger’ in T1D pregnancy management, with unanimous perception of positive impacts that far outweigh any challenges. Use of this closed-loop system has potential to vastly improve pregnancy experiences among those with T1D.</p>\u0000 </section>\u0000 </div>","PeriodicalId":11251,"journal":{"name":"Diabetic Medicine","volume":"43 11","pages":""},"PeriodicalIF":3.3,"publicationDate":"2026-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/dme.70388","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148230239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical characteristics and in-hospital mortality among insulin pump users with acute coronary syndrome in the predominantly open-loop era: A UK-wide MINAP registry analysis","authors":"Harshal Deshmukh,&nbsp;Moosa Shaikh,&nbsp;Emma G. Wilmot,&nbsp;Eric Kilpatrick,&nbsp;Sudipta Chattopadhyay,&nbsp;Thozhukat Sathyapalan,&nbsp;Joseph John","doi":"10.1111/dme.70401","DOIUrl":"10.1111/dme.70401","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>We compared characteristics of adults with insulin-treated diabetes using continuous subcutaneous insulin infusion (CSII) versus multiple daily insulin injections (MDI) during admission with acute coronary syndrome (ACS) and identified factors associated with in-hospital mortality among CSII users.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This retrospective cohort study used the Myocardial Ischaemia National Audit Project, a registry of ACS admissions in England and Wales. Adults aged ≥18 years with confirmed ACS and insulin-treated diabetes were classified as CSII or MDI users. Baseline characteristics were compared. Gradient boosting machine (GBM) modelling and multivariable logistic regression evaluated mortality predictors among CSII users.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The cohort included 3321 CSII users and 30,593 MDI users. In-hospital mortality was higher among CSII users (11.4% vs. 5.1%; <i>p</i> &lt; 0.001). CSII users had higher rates of cardiogenic shock (4.8% vs. 1.3%), pulmonary oedema (12.1% vs. 8.3%), poor left ventricular systolic function (23.5% vs. 19.7%), and STEMI (32.2% vs. 20.5%). Cardiogenic shock was the strongest predictor of mortality (adjusted OR 10.46, 95% CI 6.95–15.81), followed by poor left ventricular function (OR 4.15, 95% CI 2.69–6.53), basal crepitations (OR 1.94, 95% CI 1.40–2.67) and pulmonary oedema (OR 1.56, 95% CI 1.05–2.28). Higher systolic blood pressure was associated with lower mortality (OR 0.86 per 10 mmHg, 95% CI 0.82–0.90). The GBM model achieved an AUC of 0.85 and a Brier score of 0.088.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>CSII users admitted with ACS represented a more complex group with haemodynamic compromise and higher unadjusted mortality. Findings predominantly reflect the open-loop CSII era and may not generalise to contemporary hybrid closed-loop systems.</p>\u0000 </section>\u0000 </div>","PeriodicalId":11251,"journal":{"name":"Diabetic Medicine","volume":"43 11","pages":""},"PeriodicalIF":3.3,"publicationDate":"2026-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/dme.70401","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148379469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"It's a game changer in terms of diabetic management’: A qualitative study of adolescents' and parents' experiences of a 6-month trial of continuous glucose monitoring in type 2 diabetes","authors":"Maheesha Fernando,&nbsp;Alexia S. Peña,&nbsp;Ashlee King,&nbsp;Melissa Oxlad","doi":"10.1111/dme.70430","DOIUrl":"10.1111/dme.70430","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>To qualitatively explore adolescents with type 2 diabetes (T2D) using any treatment regimen and parents of such adolescents' experiences of a 6-month trial of continuous glucose monitoring (CGM) and its perceived barriers and facilitators.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Adolescents provided with CGM sensors (Freestyle Libre 2) free of charge for 6 months and parents recruited from the outpatient paediatric diabetes clinic at the Women's and Children's Hospital, South Australia participated. Four adolescents and six parents participated in a separate focus group or a semi-structured interview within 1 month (baseline) of CGM use; three adolescents and four parents participated in a focus group after 6 months of CGM use. Data were analysed using reflexive thematic analysis.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>We generated four themes: (1) A Convenient and Practical Tool for Adolescent Monitoring, Self-Management, Education, and Behaviour Change; (2) Enhanced Parental Diabetes Oversight and Reduced Family Emotional Burden; (3) Psychosocial, Practical, and Affordability Barriers to Adolescent CGM Use; (4) Education, Improved Adhesion, and Supportive School Environments as Facilitators of Adolescent CGM Use.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Adolescents with T2D and parents perceived CGM as a more acceptable and convenient tool than finger prick blood glucose monitoring. CGM benefits included facilitating education, improving self-management skills, and promoting behavioural modification. CGM was also perceived to reduce families' emotional burden associated with diabetes management. Device limitations, including technology accuracy, alarms, and adhesion issues, posed challenges for families. Equitable access and funding models were the main barriers to the wider adoption of CGM in this population within Australia.</p>\u0000 </section>\u0000 </div>","PeriodicalId":11251,"journal":{"name":"Diabetic Medicine","volume":"43 11","pages":""},"PeriodicalIF":3.3,"publicationDate":"2026-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/dme.70430","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148564356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Utilising glucometrics to address gaps in inpatient glycaemia management","authors":"Ji Won Susie Yoo,&nbsp;Gabrielle Blomson,&nbsp;Chelsea Albanese,&nbsp;Rahul D. Barmanray","doi":"10.1111/dme.70459","DOIUrl":"10.1111/dme.70459","url":null,"abstract":"","PeriodicalId":11251,"journal":{"name":"Diabetic Medicine","volume":"43 11","pages":""},"PeriodicalIF":3.3,"publicationDate":"2026-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148809709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Living with diabetes in the Brazilian Amazon: Exploring barriers and supports for healthy lifestyle practices","authors":"Thalyta Mariany Rêgo Lopes Ueno,&nbsp;Tiago Assunção dos Santos Farias,&nbsp;Wagner Ferreira Monteiro,&nbsp;Maria Paula dos Santos,&nbsp;Hércules Lázaro Morais Campos,&nbsp;Elisa Brosina de Leon","doi":"10.1111/dme.70381","DOIUrl":"10.1111/dme.70381","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aims</h3>\u0000 \u0000 <p>To investigate the barriers and facilitators to adopting healthy lifestyle habits among patients with type 2 diabetes mellitus (T2DM) in the Brazilian Amazon, using the Environmental Factors domain of the International Classification of Functioning, Disability and Health (ICF) as a conceptual framework.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A qualitative study was conducted with 47 patients with T2DM and 17 community health workers (CHWs) from primary health care services in the Brazilian Amazon. Data were collected through two World Café group discussion sessions (one involving patients and one involving CHWs) and 15 semi-structured interviews conducted in patients’ homes. Data were analysed using thematic analysis supported by Atlas.ti 24 software.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Three major categories emerged: attitudinal, social and physical factors. Attitudinal barriers included resistance to behaviour change, denial of disease severity and physical limitations, whereas fear of complications and valuing life motivated healthier behaviours. Social barriers comprised lack of family support, insecurity and transportation difficulties, while family involvement, professional guidance and trust in CHWs facilitated treatment adherence and lifestyle modification. Physical barriers included inadequate infrastructure, adverse weather conditions and the absence of safe public spaces for physical activity. Conversely, proximity to local markets and fairs facilitated access to healthy foods and supported dietary improvements.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Barriers and facilitators to healthy lifestyle adoption among people with T2DM in the Brazilian Amazon are strongly influenced by attitudinal, social and environmental factors. Effective diabetes management in this context requires culturally sensitive interventions, improved urban infrastructure, strengthened community support networks and continued engagement of multidisciplinary healthcare teams, particularly CHWs. These findings provide important insights for developing context-specific strategies to promote sustainable lifestyle changes, enhance patient autonomy and improve quality of life in remote Amazonian communities.</p>\u0000 </section>\u0000 </div>","PeriodicalId":11251,"journal":{"name":"Diabetic Medicine","volume":"43 11","pages":""},"PeriodicalIF":3.3,"publicationDate":"2026-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/dme.70381","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148458329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Piloting an immersive virtual reality 3D self-management education experience for adults with type 1 and type 2 diabetes mellitus: A qualitative study","authors":"Marion A. Waite,&nbsp;Olga Kozlowska,&nbsp;Clare Martin,&nbsp;Michal Krezalek,&nbsp;David Duce,&nbsp;Arantza Aldea,&nbsp;Mark Green","doi":"10.1111/dme.70383","DOIUrl":"10.1111/dme.70383","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aims</h3>\u0000 \u0000 <p>Diabetes is a condition of global concern that can be mitigated through self-management education. Virtual reality (VR) technology offers an immersive and interactive approach. It may promote self-care and access to healthcare information. This study aimed to explore the experiences of adult participants with Type 1 or Type 2 diabetes during the piloting of a 3D Automatic Virtual Reality Environment (VR-CAVE) approach to diabetes education. The study objective was to capture the participants' ideas for the future development of VR technology as a diabetes educational tool.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>We recruited fifteen adults with type 1 or 2 diabetes and invited them to a short diabetes education module in the VR-CAVE. Subsequently, we undertook qualitative focus group interviews to elicit and evaluate the participants' experiences of various design elements and their considerations for future development.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Three categories emerged: ‘Experience of an immersive learning environment for diabetes education’, ‘Comparison with prior diabetes educational experiences’ and ‘Imagined development of the VR-CAVE technology’. The participants reported a novel experience and a better understanding of the physiology of diabetes. The presence of an avatar felt non-judgemental.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Participants are open to using a VR-CAVE for diabetes education. This study identifies aspects that could be enhanced through an immersive environment. Further research is needed to realise the benefits for the diabetes community and scale-up the virtual reality resources and technology for different platforms to enable access for individuals and health service organisations.</p>\u0000 </section>\u0000 </div>","PeriodicalId":11251,"journal":{"name":"Diabetic Medicine","volume":"43 11","pages":""},"PeriodicalIF":3.3,"publicationDate":"2026-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/dme.70383","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148414595","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Understanding parents' perspectives of repeated blinded continuous glucose monitoring in children with early-stage type 1 diabetes and an affected first-degree relative","authors":"Alexandra S. Tully,&nbsp;Sabrina K. Binkowski,&nbsp;Brydie-Rose Nevin,&nbsp;Megan A. S. Penno,&nbsp;Amanda J. Anderson,&nbsp;Maria E. Craig,&nbsp;Peter G. Colman,&nbsp;Tony Huynh,&nbsp;Kelly J. McGorm,&nbsp;Georgia Soldatos,&nbsp;John M. Wentworth,&nbsp;Elizabeth A. Davis,&nbsp;Jenny J. Couper,&nbsp;Keely R. Bebbington,&nbsp;Aveni Haynes,&nbsp;the ENDIA Study Group","doi":"10.1111/dme.70424","DOIUrl":"10.1111/dme.70424","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aim</h3>\u0000 \u0000 <p>To explore the lived experiences of parents of children at risk of type 1 diabetes (T1D) undergoing repeated blinded continuous glucose monitoring (CGM).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Method</h3>\u0000 \u0000 <p>Since 2021, children with persistent islet autoimmunity in the Environmental Determinants of Islet Autoimmunity (ENDIA) study have been invited to participate in a sub-study involving blinded Dexcom G6 CGM. Parents with children undergoing repeated CGM participated in a semi-structured audio call interview. Open-ended questions captured their experiences of their child's repeated blinded CGM. Data were analysed using inductive thematic analysis.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <div>Nineteen parents (18 mothers, 1 father) of children with a mean (SD) age of 7.5 (1.3) years, who had undergone a mean 5.5 (3.2) CGM assessments, were interviewed for a mean duration of 21.3 (8.0) minutes. Three main themes were identified:\u0000\u0000 <ol>\u0000 \u0000 <li><i>Challenges of CGM wear</i>: All parents identified at least one difficult experience (e.g. pain with sensor insertion, anxiety of data loss) during CGM assessments</li>\u0000 \u0000 <li><i>Content and timing of feedback of CGM assessment findings</i>: Parents described a range of experiences related to receiving feedback from health care professionals and their child's stage of T1D.</li>\u0000 \u0000 <li><i>Preparation for diagnosis of clinical (Stage 3) T1D and initiation of insulin treatment</i>: Parents described feeling empowered by knowing their child's risk, allowing them to feel more prepared for progression to Stage 3 T1D.</li>\u0000 </ol>\u0000 </div>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Despite the challenges parents face while their child undergoes CGM assessments, they reported repeated blinded CGM as an acceptable form of monitoring that provided valuable knowledge regarding their child's risk of stage 3 type 1 diabetes.</p>\u0000 </section>\u0000 </div>","PeriodicalId":11251,"journal":{"name":"Diabetic Medicine","volume":"43 11","pages":""},"PeriodicalIF":3.3,"publicationDate":"2026-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/dme.70424","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148451360","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"When better screening is harder to deliver","authors":"Yana Lobo da Rosa Pallaoro,&nbsp;Laura Prass Schossler,&nbsp;Camila Felix Simianer,&nbsp;Hárisson Lucas Hossa,&nbsp;Gabriela Wosniak Cavaletti,&nbsp;Gabriela Pieniz Deboni,&nbsp;Lara Willers Lobato","doi":"10.1111/dme.70444","DOIUrl":"10.1111/dme.70444","url":null,"abstract":"","PeriodicalId":11251,"journal":{"name":"Diabetic Medicine","volume":"43 11","pages":""},"PeriodicalIF":3.3,"publicationDate":"2026-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148623744","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diabetes, in-hospital mortality trends and life expectancy loss among a 21.8-million population in Beijing, China, 2012–2024","authors":"Hanna Kim,&nbsp;Chang Liu,&nbsp;Ming-Jia Li,&nbsp;Hao Wang,&nbsp;Ruo-Qi Feng,&nbsp;Miao-Miao Zhao,&nbsp;Mo-Ning Guo,&nbsp;Jin-Kui Yang","doi":"10.1111/dme.70380","DOIUrl":"10.1111/dme.70380","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aims</h3>\u0000 \u0000 <p>Diabetes is a major contributor to premature mortality, but whether declining mortality trends in the general population have been matched among people with diabetes remains uncertain in China.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Retrospective cohort study based on hospitalisation records from 207 public general hospitals in Beijing (excluding community-level primary care facilities and speciality hospitals), serving the city's 21.8 million registered residents, 2012–2024. Temporal trends by Joinpoint regression, and life expectancy using abridged life tables.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Among 452,186 in-hospital deaths, 146,282 (32.3%) had diabetes. In-hospital mortality was 32.0 per 1000 admissions in patients with diabetes and 13.4 in those without diabetes. During 2012–2019, among adults ≥75 years, mortality declined in patients without diabetes (AAPC, −1.2%; <i>p</i> = 0.026) but remained stable in those with diabetes (AAPC, 0.9%; <i>p</i> = 0.082); among adults &lt;75 years, declines were smaller in patients with diabetes (−2.4% vs. −4.0%). Life expectancy—estimated from hospitalisation records as a comparative measure of survival among admitted patients—was 5.0 years lower in patients with diabetes than in those without diabetes. Loss was greater with earlier diagnosis; diagnosis at ages 20–24 years was associated with a 4.8-year reduction. Loss was larger in women than in men (5.8 vs. 2.4 years).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Diabetes was associated with substantially higher in-hospital mortality and smaller mortality improvements. Earlier diagnosis was linked to greater life expectancy loss, with disproportionate losses among women.</p>\u0000 </section>\u0000 </div>","PeriodicalId":11251,"journal":{"name":"Diabetic Medicine","volume":"43 11","pages":""},"PeriodicalIF":3.3,"publicationDate":"2026-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148177468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}