Dental and Medical Problems最新文献

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Stevia vs. triple antibiotic paste: An intracanal battle? 甜菊糖和三重抗生素糊:一场肛门内的战斗?
IF 2.7
Dental and Medical Problems Pub Date : 2024-11-01 DOI: 10.17219/dmp/161681
Raghavendra Havale, Shrutha Santhebachalli Prakasha, Sharon Elizebeth George, Namratha Tharay, Shiny Raj, Chandrabanda Bhavana, Afreen Anjum Syed, Anand Kumar, Venkatesh Naik
{"title":"Stevia vs. triple antibiotic paste: An intracanal battle?","authors":"Raghavendra Havale, Shrutha Santhebachalli Prakasha, Sharon Elizebeth George, Namratha Tharay, Shiny Raj, Chandrabanda Bhavana, Afreen Anjum Syed, Anand Kumar, Venkatesh Naik","doi":"10.17219/dmp/161681","DOIUrl":"10.17219/dmp/161681","url":null,"abstract":"<p><strong>Background: </strong>Intracanal medicaments are vital in treating the infections of the deciduous dentition due to the large percentage of accessory canals that hasten the microbial spread to the periradicular region. Though countless medicaments have been produced to reduce the microbial load and aid symptomatic relief, they still do not fulfill every function of an ideal medicament.</p><p><strong>Objectives: </strong>The aim of the present study was to evaluate and compare the antimicrobial efficacy of Stevia rebaudiana (S. rebaudiana) and triple antibiotic paste (TAP) against Enterococcus faecalis (E. faecalis).</p><p><strong>Material and methods: </strong>The present in vitro, parallel, double-blinded study had an equal allocation ratio. The specimens were prepared, randomly divided into 4 groups and inoculated with E. faecalis (ATCC35550). Following incubation, the first 3 groups were treated with S. rebaudiana, triple antibiotic therapy or carbopol gel, respectively, with the 4th negative control group left untreated. The microbial samples were collected before and after treatment, and the counts of colony-forming units (CFUs) were compared. The results were analyzed using the Kruskal-Wallis, Dunn's post-hoc and Wilcoxon's signed rank tests.</p><p><strong>Results: </strong>The first 2 groups displayed a significant decrease in CFUs after drug application, while the carbopol and control groups showed an exponential increase. There was no statistically significant difference between the stevia and TAP groups (p = 0.630).</p><p><strong>Conclusions: </strong>Stevia gel was comparable to TAP in terms of antimicrobial efficacy, and can therefore be considered a new alternative in intracanal treatment.</p>","PeriodicalId":11191,"journal":{"name":"Dental and Medical Problems","volume":" ","pages":"919-924"},"PeriodicalIF":2.7,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9835195","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
"Dental and Medical Problems": Where we are and where we are going. "牙科和医疗问题":我们的现状与未来
IF 2.7
Dental and Medical Problems Pub Date : 2024-11-01 DOI: 10.17219/dmp/194670
Mieszko Więckiewicz, Helena Martynowicz
{"title":"\"Dental and Medical Problems\": Where we are and where we are going.","authors":"Mieszko Więckiewicz, Helena Martynowicz","doi":"10.17219/dmp/194670","DOIUrl":"https://doi.org/10.17219/dmp/194670","url":null,"abstract":"<p><p>The important thing is not to stop questioning. Curiosity has its own reason for existence. One cannot help but be in awe when he contemplates the mysteries of eternity, of life, of the marvelous structure of reality. It is enough if one tries merely to comprehend a little of this mystery each day.Albert Einstein.</p>","PeriodicalId":11191,"journal":{"name":"Dental and Medical Problems","volume":"61 6","pages":"807-808"},"PeriodicalIF":2.7,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142715659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Investigating the relationship between the type of occlusion and mandibular radiomorphometric indices in patients with normal facial height. 探讨正常颜面高患者的咬合类型与下颌放射形态学指标的关系。
IF 2.7
Dental and Medical Problems Pub Date : 2024-11-01 DOI: 10.17219/dmp/130100
Ali Tayebi, Mahdi Pournaghdi, Fereshteh Aslanbeigi, Maryam Tofangchiha, Amir Javadi
{"title":"Investigating the relationship between the type of occlusion and mandibular radiomorphometric indices in patients with normal facial height.","authors":"Ali Tayebi, Mahdi Pournaghdi, Fereshteh Aslanbeigi, Maryam Tofangchiha, Amir Javadi","doi":"10.17219/dmp/130100","DOIUrl":"10.17219/dmp/130100","url":null,"abstract":"<p><strong>Background: </strong>The ability to predict the extent and direction of horizontal growth of the patient's face at an early age allows clinicians to timely identify cases that require treatment during the growth period and to ensure that appropriate treatment can be administered.</p><p><strong>Objectives: </strong>The aim of this study was to investigate the role of the antegonial angle, gonial angle, antegonial notch depth, and the type of the antegonial notch on predicting horizontal facial growth in individuals with normal facial height.</p><p><strong>Material and methods: </strong>In this descriptive analytic study, lateral and panoramic radiographs of 180 patients aged 17-30 years with normal facial height who were referred to the School of Dentistry of Qazvin University of Medical Sciences and private dental clinics were investigated. The indices of the gonial angle, antegonial angle, type of antegonial notch, and antegonial notch depth were plotted bilaterally on tracing paper and subsequently measured using panoramic radiographs. Additionally, the relationship between the desired radiomorphometric indices and the occlusion class in the samples was investigated.</p><p><strong>Results: </strong>There was a statistically significant relationship between the occlusion class and the antegonial notch depth (analysis of variance (ANOVA), p = 0.048), as well as the antegonial angle (Kruskal-Wallis test, p = 0.002).</p><p><strong>Conclusions: </strong>The results of this study indicate that the antegonial notch depth and angle indices can be clinically valuable in predicting the process of mandibular growth and developing appropriate treatment plans.</p>","PeriodicalId":11191,"journal":{"name":"Dental and Medical Problems","volume":"61 6","pages":"829-835"},"PeriodicalIF":2.7,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142799715","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessment of the effectiveness of a rotatable shank toothbrush compared to a conventional handle toothbrush: A multicenter, single-blind, randomized controlled trial. 可旋转柄牙刷与传统柄牙刷的有效性评估:一项多中心、单盲、随机对照试验。
IF 2.7
Dental and Medical Problems Pub Date : 2024-11-01 DOI: 10.17219/dmp/168373
Gowri Swaminatham Pendyala, Pradeep Kumar Chaudhary, Babita Ratnakar Pawar, Ameet Mani, Saurabh Ramesh Joshi
{"title":"Assessment of the effectiveness of a rotatable shank toothbrush compared to a conventional handle toothbrush: A multicenter, single-blind, randomized controlled trial.","authors":"Gowri Swaminatham Pendyala, Pradeep Kumar Chaudhary, Babita Ratnakar Pawar, Ameet Mani, Saurabh Ramesh Joshi","doi":"10.17219/dmp/168373","DOIUrl":"10.17219/dmp/168373","url":null,"abstract":"<p><strong>Background: </strong>The persistence of dental plaque is attributable to the inaccessibility to all surfaces of the oral cavity. Thus, an integrated team designed an innovative toothbrush comprising a brush head assembly with an upper end and a lower end, and a handle rotatably configured with the lower end of the brush head assembly. The brush head is connected to the handle through a socket-ball joint, which allows the shank and the handle to rotate at any angle between 0° and 360° with respect to one another around an axis. Additionally, the brush head bends toward the handle, maintaining a bending angle of 15°.</p><p><strong>Objectives: </strong>The aim of the present randomized controlled trial (RCT) was to analyze and assess the effectiveness of a toothbrush with a rotatable shank in comparison to toothbrushes with flexible and straight handles with respect to supragingival plaque and gingival health outcomes. The secondary objective of the study was to evaluate the feedback of individuals who used the rotatable shank toothbrush.</p><p><strong>Material and methods: </strong>Three toothbrushes - one with a rotatable shank, one with a flexible handle and one with a straight handle - were compared in terms of efficacy in plaque and gingivitis control at 3 clinical centers (a multicenter trial). A total of 270 patients, aged 18-65 years, were included in the study. The collected data was analyzed and compared using the analysis of variance (ANOVA) with Tukey's post hoc test.</p><p><strong>Results: </strong>All groups demonstrated improvement in gingival health and a reduction in the plaque index (PI) scores. Nonetheless, the improvement was more pronounced in the group that used the toothbrush with a rotatable shank.</p><p><strong>Conclusions: </strong>The enhanced plaque removal and improved gingival health at all surfaces achieved with the rotatable shank toothbrush are ascribable to the incorporation of 2 features: the ability to rotate the toothbrush neck along its axis; and an inclination that facilitates access to all surfaces.</p>","PeriodicalId":11191,"journal":{"name":"Dental and Medical Problems","volume":"61 6","pages":"809-820"},"PeriodicalIF":2.7,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142799712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Polymorphisms within genes encoding Ikaros family proteins IKZF1 and IKZF3 in multiple myeloma patients treated with thalidomide. 在接受沙利度胺治疗的多发性骨髓瘤患者中,Ikaros家族蛋白IKZF1和IKZF3基因的多态性
IF 2.7
Dental and Medical Problems Pub Date : 2024-11-01 DOI: 10.17219/dmp/183776
Piotr Łacina, Diana Porzuczek, Katarzyna Bogunia-Kubik, Grzegorz Mazur, Aleksandra Butrym
{"title":"Polymorphisms within genes encoding Ikaros family proteins IKZF1 and IKZF3 in multiple myeloma patients treated with thalidomide.","authors":"Piotr Łacina, Diana Porzuczek, Katarzyna Bogunia-Kubik, Grzegorz Mazur, Aleksandra Butrym","doi":"10.17219/dmp/183776","DOIUrl":"10.17219/dmp/183776","url":null,"abstract":"<p><strong>Background: </strong>Multiple myeloma (MM) is a hematological malignancy characterized by the presence of abnormal plasma cells. It is associated with anemia, bone lesions and renal dysfunction. Immunomodulatory drugs (IMiDs) are commonly used in MM treatment. Recent studies indicate that their therapeutic effect is caused by binding to cereblon (CRBN), which in turn causes the degradation of 2 important immune cell regulatory factors, IKZF1 and IKZF3. These are necessary for the anti-myeloma effect of IMiDs. Their expression level has been shown to affect MM survival and response to treatment. Potentially important single-nucleotide polymorphisms (SNPs) in the genes coding for IKZF1 and IKZF3 have been identified, but they have not been analyzed in MM patients before.</p><p><strong>Objectives: </strong>The study was designed to establish the relationship between 4 SNPs in the genes coding for IKZF1 (rs61731359, rs4132601 and rs10272724) and IKZF3 (rs907091), and MM survival, response to treatment and other parameters.</p><p><strong>Material and methods: </strong>The study involved 222 MM patients, as well as 100 control individuals. The IKZF1 and IKZF3 genotypes were determined by the LightSNiP assay. Genotyping was performed in the real-time polymerase chain reaction (PCR) LightCycler 480 device.</p><p><strong>Results: </strong>No difference was observed between the patients and the controls for any of the SNPs, but the IKZF1 and IKZF3 variants were associated with various clinical parameters. Allele IKZF1 rs4132601 G was more common in the patients with worse response to first-line therapy (p = 0.040), particularly in the patients treated with thalidomide (p = 0.017). The patients tended to have worse overall survival. IKZF3 rs907091 CC was detected more commonly in the patients in stage I than in those in stages II and III, according to the International Staging System (ISS) criteria (p = 0.015). This genotype was also associated with a higher albumin level (p = 0.033), and was less common in the patients with the albumin level below 3.5 g/dL (p = 0.030).</p><p><strong>Conclusions: </strong>Our results suggest that IKZF1 rs4132601 and IKZF3 rs907091 may affect response to treatment and progression in patients with MM.</p>","PeriodicalId":11191,"journal":{"name":"Dental and Medical Problems","volume":"61 6","pages":"885-892"},"PeriodicalIF":2.7,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142863622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Patient satisfaction among subjects with a maxillary single denture, treated with implant-supported telescopic versus ball-and-socket overdentures: A randomized controlled trial. 上颌单口义齿患者对种植支撑套筒义齿与球窝覆盖义齿的满意度:一项随机对照试验。
IF 2.7
Dental and Medical Problems Pub Date : 2024-11-01 DOI: 10.17219/dmp/169186
Sherihan Hanafy Salem, Ali Abdulghani AlSourori, Marwa Hassan Mostafa
{"title":"Patient satisfaction among subjects with a maxillary single denture, treated with implant-supported telescopic versus ball-and-socket overdentures: A randomized controlled trial.","authors":"Sherihan Hanafy Salem, Ali Abdulghani AlSourori, Marwa Hassan Mostafa","doi":"10.17219/dmp/169186","DOIUrl":"10.17219/dmp/169186","url":null,"abstract":"<p><strong>Background: </strong>The present study was performed to rehabilitate maxillary single denture cases with implantretained telescopic or ball-and-socket attachments, and to evaluate the validity of two-implantretained maxillary overdentures as a treatment approach in the maxillary arch.</p><p><strong>Objectives: </strong>The aim of the present study was to evaluate patient satisfaction in maxillary single denture wearers with 2 different attachment systems (telescopic attachment vs. ball-and-socket attachment).</p><p><strong>Material and methods: </strong>A total of 18 completely edentulous maxillary ridge patients (45-60 years old; mean age: 53 years) were selected for this study. Maxillary single dentures were constructed for all the patients. Group 1 patients received 2 implants with a telescopic attachment and group 2 patients received 2 implants with a ball-and-socket attachment. Patient satisfaction with the implant-retained maxillary single denture was evaluated after insertion, and 3 months after the delivery of each implant-retained maxillary single overdenture.</p><p><strong>Results: </strong>All 18 patients completed the study. After 3 months, the telescopic group showed significant improvement in terms of comfort, chewing, handling, and overall satisfaction, and in the ball-and-socket group, significant improvement was recorded for appearance only. When comparing the 2 groups, after insertion, group 1 showed significantly better results for the 'handling' and 'hygiene' parameters, whereas group 2 showed a significantly better mean score for the 'appearance' parameter. After 3 months, group 1 showed significantly better results for the 'comfort', 'handling', 'hygiene', and 'overall satisfaction' parameters, and group 1 proved significantly better in terms of 'appearance' and 'speech' parameters.</p><p><strong>Conclusions: </strong>Maxillary single dentures with a telescopic attachment showed an advantage over those with a ball-and-socket attachment regarding patient satisfaction. Concerning the implant number, twoimplantretained maxillary overdentures can be considered a promising approach for patients from developing countries.</p>","PeriodicalId":11191,"journal":{"name":"Dental and Medical Problems","volume":"61 6","pages":"821-828"},"PeriodicalIF":2.7,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142863606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
YouTube videos as an information source about exercises for temporomandibular disorders. YouTube视频是关于颞下颌疾病锻炼的信息来源。
IF 2.7
Dental and Medical Problems Pub Date : 2024-11-01 DOI: 10.17219/dmp/170922
Özlem Nur Tok, Ayşe Nihal Yurttaş, Serkan Taş
{"title":"YouTube videos as an information source about exercises for temporomandibular disorders.","authors":"Özlem Nur Tok, Ayşe Nihal Yurttaş, Serkan Taş","doi":"10.17219/dmp/170922","DOIUrl":"10.17219/dmp/170922","url":null,"abstract":"<p><strong>Background: </strong>Temporomandibular disorders (TMD) are musculoskeletal and/or neuromuscular conditions that affect the muscles, joints and associated structures of the stomatognathic system.</p><p><strong>Objectives: </strong>This study aimed to evaluate the quality and reliability of publicly available English-language videos on YouTube about TMD exercises, and to examine the video sources and professional groups responsible for the creation of the videos.</p><p><strong>Material and methods: </strong>The quality and reliability of the YouTube videos related to TMD exercises were evaluated using the DISCERN score, the global quality scale (GQS) and the JAMA (Journal of the American Medical Association) score.</p><p><strong>Results: </strong>Of the 121 videos evaluated, 30 (24.8%) were uploaded by professional organizations, 49 (40.5%) by health information websites, and 42 (34.7%) were uploaded by independent users. Professional organizations had a significantly higher number of subscribers, likes, comments, and views than healthcare webpages and independent users (p < 0.001). The duration of videos uploaded by independent users was significantly longer than that of videos uploaded by healthcare webpages (p = 0.018). With regard to the profession of the video narrators, the unspecified group exhibited significantly lower JAMA (p < 0.001), GQS (p = 0.011) and DISCERN scores (p = 0.002) compared to chiropractors, physiotherapists, physicians, and other healthcare professionals. The JAMA scores for physicians, personal trainers and chiropractors were significantly lower than those for other healthcare professionals (p < 001). The JAMA score was positively correlated with the GQS (r = 0.469, p < 0.001) and DISCERN (r = 0.505, p < 0.001) scores. Similarly, the DISCERN score was positively correlated with the GQS score (r = 0.924, p < 0.001).</p><p><strong>Conclusions: </strong>Despite the abundance of video content on YouTube about TMD exercises, the quality of these videos is low, and their reliability is questionable.</p>","PeriodicalId":11191,"journal":{"name":"Dental and Medical Problems","volume":"61 6","pages":"855-863"},"PeriodicalIF":2.7,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142799716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Most common congenital syndromes with facial asymmetry: A narrative review. 最常见的面部不对称先天综合症:叙述性综述。
IF 2.7
Dental and Medical Problems Pub Date : 2024-11-01 DOI: 10.17219/dmp/186086
Anna Maria Paradowska-Stolarz, Marta Ziomek, Katarzyna Sluzalec-Wieckiewicz, Irena Duś-Ilnicka
{"title":"Most common congenital syndromes with facial asymmetry: A narrative review.","authors":"Anna Maria Paradowska-Stolarz, Marta Ziomek, Katarzyna Sluzalec-Wieckiewicz, Irena Duś-Ilnicka","doi":"10.17219/dmp/186086","DOIUrl":"10.17219/dmp/186086","url":null,"abstract":"<p><p>Symmetry is present in various aspects of everyday life. A symmetrical face is considered attractive, whereas a lack of facial symmetry is regarded as a source of functional and aesthetic problems. Most of the people exhibit slight asymmetries, but some of them reveal severe asymmetries. Among patients presenting with severe facial asymmetries, there may be those with congenital defects. Congenital defects may manifest at the time of birth or be a result of birth trauma.One of the most prevalent asymmetrical birth defects is cleft lip and/or cleft palate. Other congenital defects include craniofacial syndromes, such as Treacher Collins syndrome (TCS) and Goldenhar syndrome. Among the rare syndromes with facial asymmetries, Klippel-Feil syndrome (KFS), PHACE (posterior fossa brain malformation, hemangiomas, arterial anomalies, cardiac anomalies, and eye abnormalities) syndrome, plagiocephaly, and Parry-Romberg syndrome are worth noticing. The majority of craniofacial asymmetries require surgery to improve the patient's facial appearance. The treatment is multidisciplinary and long, and the most common procedures involve reparative and regenerative surgeries. The aim of this review was to present the most common congenital defects with facial asymmetry.</p>","PeriodicalId":11191,"journal":{"name":"Dental and Medical Problems","volume":" ","pages":"925-932"},"PeriodicalIF":2.7,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142575372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of the association between periodontal disease and total cancer risk: A cross-sectional study. 评估牙周病与总癌症风险之间的关系:一项横断面研究。
IF 2.7
Dental and Medical Problems Pub Date : 2024-11-01 DOI: 10.17219/dmp/175001
Ruchi Banthia, Parul Jain, Ashish Kumar Jain, Sphoorthi Anup Belludi, Neha Agarwal, Madhvika Patidar
{"title":"Evaluation of the association between periodontal disease and total cancer risk: A cross-sectional study.","authors":"Ruchi Banthia, Parul Jain, Ashish Kumar Jain, Sphoorthi Anup Belludi, Neha Agarwal, Madhvika Patidar","doi":"10.17219/dmp/175001","DOIUrl":"10.17219/dmp/175001","url":null,"abstract":"<p><strong>Background: </strong>The body is in a continuous state of inflammatory burden due to local and systemic inflammation, which is triggered in periodontal tissues in response to microorganisms. A number of studies have linked periodontitis to systemic diseases such as diabetes mellitus, cardiovascular disease and respiratory disease. Periodontal inflammation acts as a focus of infection, which can cause detrimental effects on distant target organs. In some cases, it may lead to tumor progression in various cancers.</p><p><strong>Objectives: </strong>The aim of the study was to evaluate the correlation between periodontal disease (PD) and its potential role as a risk factor for the development of systemic cancer and its metastasis.</p><p><strong>Material and methods: </strong>A single-center, cross-sectional study was conducted, including 66 patients with different systemic malignancies (group 1, the test group) and 66 healthy individuals (group 2, the control group). Group 1 was further subdivided into 2 categories: M0, comprising patients without metastases (n = 34); and M1, comprising patients with distant metastases (n = 32). The number of missing teeth, Greene and Vermilion's simplified oral hygiene index (OHI-S), probing pocket depth (PPD), Löe and Silness' bleeding on probing (BoP), clinical attachment loss (CAL), and Ramfjord's periodontal disease index (PDI) were recorded. Appropriate statistical tests were performed to analyze the data. A p-value <0.05 was considered statistically significant.</p><p><strong>Results: </strong>The differences between the PDI, CAL and PPD values in both group 1 and group 2 were found to be statistically significant (p = 0.000). In M0 and M1, no statistically significant differences were observed between any of the parameters. The odds ratios (ORs) between group 1 and group 2 for CAL and PDI were 3.986 and 4.286, respectively. The ORs for M0 and M1 with regard to CAL and the mean number of teeth lost were 0.373 and 0.188, respectively.</p><p><strong>Conclusions: </strong>The findings of the study indicate a significant association between the overall risk of cancer and PD. In cases of known systemic malignancies, no significant correlation has been identified between PD and the risk of metastasis.</p>","PeriodicalId":11191,"journal":{"name":"Dental and Medical Problems","volume":"61 6","pages":"843-850"},"PeriodicalIF":2.7,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142799714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Advancements in alveolar bone reconstruction: A systematic review of bone block utilization in dental practice. 牙槽骨重建的进展:牙科实践中骨块使用情况的系统回顾。
IF 2.7
Dental and Medical Problems Pub Date : 2024-11-01 DOI: 10.17219/dmp/181532
Sylwia Hnitecka, Cyprian Olchowy, Anna Olchowy, Paweł Dąbrowski, Marzena Dominiak
{"title":"Advancements in alveolar bone reconstruction: A systematic review of bone block utilization in dental practice.","authors":"Sylwia Hnitecka, Cyprian Olchowy, Anna Olchowy, Paweł Dąbrowski, Marzena Dominiak","doi":"10.17219/dmp/181532","DOIUrl":"10.17219/dmp/181532","url":null,"abstract":"<p><p>Alveolar reconstructive surgery employs a variety of surgical techniques and biomaterials, with a particular focus on bone blocks as a crucial methodology for restoring and augmenting deficient bone structures. Bone blocks are often employed to support periodontal health or as a foundation for future prosthetic rehabilitation with dental implants. This systematic review investigated recent advances in bone blocks for alveolar bone reconstruction, comparing autologous, allogeneic and xenogeneic types. A search of PubMed identified 56 records, of which 21 were included in the qualitative analysis. The studies involved 685 patients in total. Bone blocks are pivotal for three-dimensional bone regeneration, providing a stable scaffold for achieving the desired bone volume during healing. Autologous bone, harvested from the patient, boasts high biocompatibility, excellent osteogenic properties and minimal immunologic risks. However, its drawbacks include the need for an additional surgical site and extended procedural times. Allogeneic bone blocks involve transferring bone between individuals, offering increased graft availability and customization options without requiring a second surgical site. However, they exhibit moderate resorption rates and carry a heightened risk of immunologic reactions and disease transmission. Innovative techniques, such as tunneling, laser osteotomy, graft customization, and platelet-rich fibrin (PRF) application on wound during surgical treatment show promise in enhancing alveolar bone reconstruction efficacy. In conclusion, despite the traditional preference for autologous bone, the review suggests that alternative materials, particularly individualized allogeneic bone blocks, coupled with modern techniques, could emerge as a standard procedure for regenerating alveolar bone defects due to their satisfactory results and potential advantages.</p>","PeriodicalId":11191,"journal":{"name":"Dental and Medical Problems","volume":" ","pages":"933-941"},"PeriodicalIF":2.7,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141080936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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