Current rheumatology reviews最新文献

{"title":"Bibliometric Analysis of Capillaroscopy Use in Systemic Sclerosis: Current State and Advances from 2000 to 2024.","authors":"Sevil Ceyhan Doğan, Mert Atas","doi":"10.2174/0115733971388040250815185341","DOIUrl":"https://doi.org/10.2174/0115733971388040250815185341","url":null,"abstract":"<p><strong>Introduction: </strong>Systemic sclerosis is a complex autoimmune disease characterized by diverse clinical manifestations that vary among individuals. It is associated with significant morbidity and mortality. This study aimed to evaluate the existing literature on the use of capillaroscopy in systemic sclerosis and to perform a bibliometric analysis.</p><p><strong>Methods: </strong>Data were downloaded from Scopus on 2nd October 2024, and analyzed using VOSviewer and the Biblioshiny package programs.</p><p><strong>Results: </strong>A total of 819 articles from 246 sources were analyzed. Italy led in the number of publications (n=209) and the frequency of international cooperation. The article, titled \"Nailfold Videocapillaroscopy Assessment of Microvascular Damage in Systemic Sclerosis,\" published in The Journal of Rheumatology, has garnered 606 citations, making it the most cited article. Cutolo M. was the most influential author, with 1302 citations and 107 publications, while the University of Genova was the most prolific institution. The investigation identified significant issue clusters in the literature related to keywords, such as \"systemic sclerosis,\" \"Raynaud's phenomenon,\" \"capillaroscopy,\" and \"digital ulcers.\"</p><p><strong>Discussion: </strong>This study presents the first comprehensive bibliometric analysis of capillaroscopy use in systemic sclerosis. The findings suggest that scientific interest in the subject is increasing and that research leadership is primarily located in European countries, with Italy at the forefront. The most frequently used keywords in the thematic analysis indicated that capillaroscopy can be used not only for diagnosis but also for monitoring complications. The use of only the Scopus database and the inclusion of only original articles in the study constitute limitations. This methodological choice was made to ensure data integrity.</p><p><strong>Conclusion: </strong>Understanding the research on capillaroscopy applications in systemic sclerosis can benefit rheumatologists and provide ideas for future investigations. This bibliometric analysis highlights key authors, citation patterns, collaboration structures, and emerging research issues over the past two decades, providing a comprehensive overview of the discipline.</p>","PeriodicalId":11188,"journal":{"name":"Current rheumatology reviews","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144946380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Integrative Rheumatology: A Holistic Approach to the Management of Systemic Lupus Erythematosus.","authors":"Ailia Ali, Kichul Ko, Kimberly Trotter","doi":"10.2174/0115733971389117250807101431","DOIUrl":"https://doi.org/10.2174/0115733971389117250807101431","url":null,"abstract":"<p><strong>Background: </strong>Integrative medicine, which combines complementary and alternative medicine (CAM) with conventional treatments, is increasingly utilized by patients with systemic lupus erythematosus (SLE) to manage their condition.</p><p><strong>Objective: </strong>This study aims to review the CAM available for SLE patients.</p><p><strong>Methods: </strong>Studies focusing on CAM interventions in patients diagnosed with SLE were identified via PubMed, Scopus, Cochrane Library, and Google Scholar through a systematic search conducted to identify relevant articles published up to May 2024.</p><p><strong>Results: </strong>The potential therapeutic roles of specific micronutrients (vitamins A, C, D, and E), macronutrients (omega-3 fatty acids and probiotics), and supplements (ginger, turmeric) were examined, detailing their mechanisms and emerging evidence supporting their use. Additionally, the roles of dietary changes and mind-body interventions were discussed.</p><p><strong>Conclusion: </strong>Despite the absence of established guidelines for supplementation and other interventions, this review emphasizes the need for personalized approaches tailored to individual characteristics and comorbidities. Healthcare providers are encouraged to enhance their knowledge of these CAM modalities to optimize patient care and improve overall quality of life for SLE patients.</p>","PeriodicalId":11188,"journal":{"name":"Current rheumatology reviews","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144946313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An Unusual Complication of Intralesional Corticosteroid Injections: Two Case Reports.","authors":"Omayma Khadiri, Rim Kaoua, Maryem Aboudourib, Said Amal, Ouafa Hocar","doi":"10.2174/0115733971368413250730095105","DOIUrl":"https://doi.org/10.2174/0115733971368413250730095105","url":null,"abstract":"<p><strong>Background: </strong>Intralesional corticosteroid injections are widely used for treating various inflammatory and musculoskeletal conditions. While generally safe, they can cause adverse effects, including hypopigmentation, which may have psychosocial implications for affected patients.</p><p><strong>Case presentation: </strong>We report two cases of hypopigmentation following intralesional triamcinolone acetonide injections. The first case involves a 65-year-old man who developed a well- defined hypopigmented patch on the dorsum of his right hand following treatment for De Quervain's tenosynovitis. The second case describes a 25-year-old patient who presented with linear hypopigmentation along the anterior aspect of his left foot after an intra-articular injection for a synovial cyst. In both cases, hypopigmentation was confirmed using Wood's lamp examination, and spontaneous improvement was noted over time.</p><p><strong>Conclusion: </strong>Clinicians should be aware of this potential side effect when administering corticosteroid injections and inform patients accordingly. While hypopigmentation is typically self-limiting, patient education and reassurance are essential, particularly for individuals with darker skin types.</p>","PeriodicalId":11188,"journal":{"name":"Current rheumatology reviews","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144783740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Discoid Lupus Flare with Chondritis Triggered by Eaton Fire Case Report.","authors":"Sofia Audrey B Gonzales, Kiana Mortezaei, Daniel G Arkfeld","doi":"10.2174/0115733971396962250721111020","DOIUrl":"https://doi.org/10.2174/0115733971396962250721111020","url":null,"abstract":"<p><strong>Introduction: </strong>Systemic Lupus Erythematosus (SLE) is a chronic autoimmune disorder with flare-ups often triggered by environmental stressors. While stress is a known trigger for lupus exacerbations, the relationship between environmental stressors, lupus flares, and discoid lupus erythematosus remains underexplored. This case report examines a patient whose symptoms worsened after exposure to the Eaton fire.</p><p><strong>Case presentation: </strong>A 57-year-old female with lupus reported a flare following the Eaton fire, which severely damaged her parents' home. Symptoms began 12 hours after the fire. Examination revealed erythema and deformity in both ears, consistent with chondritis. After starting a prednisone taper, her condition improved within two weeks.</p><p><strong>Conclusion: </strong>Environmental stressors, like natural disasters, can trigger lupus flare-ups and conditions, such as discoid lupus erythematosus (DLE). Stress-induced immune dysregulation exacerbates autoimmune responses, making it challenging to differentiate discoid lupus from other lupus manifestations. This case highlights the need for recognizing environmental triggers in lupus management and further research into the role of stress in lupus flare-ups.</p>","PeriodicalId":11188,"journal":{"name":"Current rheumatology reviews","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144741614","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Case Report of an Atypical Presentation of Inclusion Body Myositis Masquerading as Polymyalgia Rheumatica.","authors":"Pallavi Velagapudi, Diego Lugo Baruqui, Ahmed Elghawy, Carlos Pena","doi":"10.2174/0115733971361017250619105000","DOIUrl":"https://doi.org/10.2174/0115733971361017250619105000","url":null,"abstract":"<p><strong>Introduction: </strong>Idiopathic inflammatory myopathies are a group of rheumatologic disorders presenting with progressive muscle weakness and the presence of inflammatory infiltrates in muscle tissue on histopathology. Inclusion body myositis classically has an insidious onset and slow progression and affects the older population, most commonly men. Muscle weakness is usually asymmetric and involves the distal upper extremity muscle groups.</p><p><strong>Case presentation: </strong>This case describes a 59-year-old man presenting with worsening symmetrical upper and lower extremity proximal muscle weakness and disabling muscle pain in his shoulders and hips. Further, weakly positive antinuclear antibodies were also observed. The creatinine phosphokinase was also remarkably elevated, uncharacteristic of both inclusion body myositis and polymyalgia rheumatica. He was initially thought to have polymyalgia rheumatica, but given the time frame and the presence of muscle pain, a muscle biopsy was done, which confirmed the inclusion body myositis.</p><p><strong>Conclusion: </strong>This case underscores the challenges in diagnosing inclusion body myositis due to its slow progression and overlapping features with other conditions, highlighting the importance of recognizing its distinguishing characteristics.</p>","PeriodicalId":11188,"journal":{"name":"Current rheumatology reviews","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144526807","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Structural and Molecular Effects of Dextrose on Cartilage: A Scoping Review.","authors":"Pedro Iván Arias-Vázquez, Kenneth D Reeves, Rosa Giannina Castillo-Avila, Gastón A Topol, Ricardo Quezada-González, Pavel Loeza-Magaña, Elizabeth Carmona-Díaz, Eduardo De la Cruz-Cano, Daniel Cadena-Sandoval","doi":"10.2174/0115733971386046250611073643","DOIUrl":"https://doi.org/10.2174/0115733971386046250611073643","url":null,"abstract":"<p><strong>Background: </strong>Dextrose prolotherapy has been used in the treatment of individuals with osteoarthritis in various locations, reporting favorable therapeutic effects. However, the molecular and/or structural effects of dextrose prolotherapy on cartilage are still unclear. Therefore, this study aimed to analyze the molecular and/or structural effects of dextrose on cartilage and clarify the possible mechanisms of action of dextrose prolotherapy.</p><p><strong>Methods: </strong>A systematic search was conducted using scientific databases, including PubMed, Web of Science, Cochrane Central Register of Controlled Trials, and ScienceDirect, up until November 2024, using the PRISMA-ScR for Scoping Reviews.</p><p><strong>Results: </strong>Twenty-three studies that evaluated the molecular and/or structural effects of dextrose on cartilage were eligible for inclusion. Fifteen studies included in vitro models, three studies involved animal models, and five studies were conducted on humans. Sixteen studies reported favorable effects on cartilage, and seven studies reported unfavorable effects. In all studies performed in vivo (in animals or humans), predominantly favorable effects on cartilage were reported. The favorable effects on cartilage were improved glucose metabolism in chondrocytes, increased deposition of extracellular matrix and the induction of chondrocyte proliferation, increased expression of anabolic growth factors and anti-inflammatory cytokines, as well as decreased activity of some metalloproteinases. Among the unfavorable effects, increased release of proinflammatory and catabolic cytokines was reported.</p><p><strong>Conclusion: </strong>These results suggest that dextrose may have a therapeutic effect on cartilage, though the underlying mechanisms are not fully understood. This study is a starting point for fu-ture experimental studies evaluating the therapeutic effects of dextrose prolotherapy.</p>","PeriodicalId":11188,"journal":{"name":"Current rheumatology reviews","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144539489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rheumatoid Arthritis and Secondary Plant Metabolites: An Analysis.","authors":"Vandana Bhatia, Vir Vikram Sharma, Shagun Thakur, Anjali Chandel, Yavnika Minhas","doi":"10.2174/0115733971336322250605063028","DOIUrl":"https://doi.org/10.2174/0115733971336322250605063028","url":null,"abstract":"<p><p>Chronic rheumatoid arthritis (RA) is a systemic inflammatory disease characterized by persistent joint inflammation, progressive joint destruction, and chronic pain. Although modern therapies like disease-modifying antirheumatic medications (DMARDs) can alleviate symptoms, they may also produce side effects. Because of their anti-inflammatory, antioxidant, and immunomodulatory qualities, plant secondary metabolites such as flavonoids, terpenoids, alkaloids, and phenolic acids have attracted attention as prospective RA treatment agents. This review discusses the pathogenesis of RA and provides an overview of various plant secondary metabolites and their biological activities relevant to RA. It highlights preclinical and clinical studies that have investigated the use of plant metabolites in RA management, demonstrating their potential to reduce inflammation, modulate immune responses, and protect joint structures. The review explores the potential molecular targets and mechanisms of action of plant metabolites in RA, including inflammatory mediators, transcription factors, signalling pathways, oxidative stress, immune cell regulation, cell proliferation and apoptosis, cartilage and bone metabolism, and angiogenesis. Additionally, the challenges and considerations in developing plant-based therapies for RA are discussed, such as efficacy and safety, standardization, bioavailability, regulatory approval, and patient compliance. Finally, future perspectives and research directions are outlined, emphasizing the need for further mechanistic studies, preclinical and clinical investigations, formulation strategies, and interdisciplinary collaborations to fully harness the therapeutic potential of plant secondary metabolites in RA management.</p>","PeriodicalId":11188,"journal":{"name":"Current rheumatology reviews","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144505091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinicodemographic Data of Patients with Behçet's Disease: Data from a Tertiary Center in Saudi Arabia.","authors":"Yasser Bawazir, Mohammad Mustafa","doi":"10.2174/0115733971359862250603040950","DOIUrl":"https://doi.org/10.2174/0115733971359862250603040950","url":null,"abstract":"<p><strong>Introduction: </strong>Behçet's disease (BD) is a chronic inflammatory vasculitis involving the arteries and veins. This study was driven by the rarity, chronic multisystemic nature, and heterogeneous spectrum of clinical features and geographical distribution. This study aimed to analyze the demographic and clinical characteristics of patients with BD at the King Abdulaziz University Hospital and identify the association between clinical and laboratory findings and disease severity.</p><p><strong>Methods: </strong>The study was a retrospective core chart review. This study included adult patients who visited the rheumatology clinic of King Abdulaziz University Hospital in Saudi Arabia between 2005 and 2023. The inclusion criteria were age ≥18 years and a diagnosis of Behçet's disease (BD) based on either the International Criteria for Behçet's Disease or the International Study Group classification criteria.</p><p><strong>Results: </strong>In total, 81 patients with BD with almost equal male (51.9%) and female (48.1%) distribution, 75.3% Saudi nationals, mean onset age of 38.48 years, and mean body mass index of 27.57 kg/m2 were identified. The most common clinical manifestations were oral ulcerations (56.8%), genital ulcerations (37%), uveitis (24.7%), arthritis (22.2%), skin lesions (13.6%), and deep vein thrombosis (9.88%). Significant differences in high-density lipoprotein, hemoglobin, Creactive protein, and albumin levels were associated with the age, sex, and nationality of the patients, respectively. Similarly, body mass index was significantly associated with C-reactive protein (p = 0.004), alanine aminotransferase (p = 0.023), aspartate aminotransferase (p = 0.003), and gamma-glutamyl aminotransferase (p = 0.034) levels.</p><p><strong>Conclusion: </strong>This study demonstrated that there are significant associations between demographic factors, laboratory parameters, and BD activity.</p>","PeriodicalId":11188,"journal":{"name":"Current rheumatology reviews","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144282831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring the Therapeutic Potential of Nanocarrier-Mediated Drug Delivery in Rheumatoid Arthritis (RA) Treatment.","authors":"Shivani Pannu, Rahul Pal, Inderjeet Verma","doi":"10.2174/0115733971345399250529170645","DOIUrl":"https://doi.org/10.2174/0115733971345399250529170645","url":null,"abstract":"<p><p>Rheumatoid arthritis (RA) is a chronic autoimmune disorder that leads to severe joint damage, persistent inflammation, and an increase in synovial tissue. While existing treatment modalities such as corticosteroids, disease-modifying antirheumatic drugs (DMARDs), and nonsteroidal anti-inflammatory drugs (NSAIDs) can alleviate symptoms, they frequently come with systemic side effects and do not always achieve satisfactory disease remission. Moreover, the broad distribution of these medications can result in off-target toxicity and inadequate drug levels at the affected joints. This study aims to explore the therapeutic capabilities of drug delivery systems (DDs) utilizing nanocarriers for RA management. The focus is on evaluating how these nanocarriers can facilitate targeted, efficient, and safer drug delivery by concentrating on inflamed joint tissues, minimizing systemic toxicity, and enhancing drug uptake at the disease site. This review analyzes various nanocarrier types, including liposomes, polymeric nanoparticles (NPs), dendrimers, micelles, and hybrid systems. A review of over 100 original research articles on RA treatment was conducted, drawing from platforms such as Google Scholar, ResearchGate, official websites, and raw data. The application of nanocarriers in RA therapy has demonstrated considerable potential in enhancing the precision and effectiveness of drug delivery. By enabling higher concentrations of medication directly at the inflammation site, nanocarrier-mediated drug delivery systems can mitigate systemic side effects and improve therapeutic outcomes. These systems present a promising approach to overcoming the limitations of current RA treatments, offering more targeted, efficient, and safer therapeutic alternatives. Nonetheless, additional research and development are essential to fully harness the capabilities of nanocarrier systems in RA treatment and to refine their clinical implementation.</p>","PeriodicalId":11188,"journal":{"name":"Current rheumatology reviews","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144207977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigating the Relationship between Work-Related Musculoskeletal Disorders and the Quality of Life of Agricultural Workers.","authors":"Reza Faryabi, Shima Groohi-Sardou, Rasoul Raesi, Kiavash Hushmandi, Salman Daneshi, Habibe Vaziri Nasab, Fatemeh Bagher Barahouei, Esmaeil Barkhori Mehni","doi":"10.2174/0115733971355486250528163102","DOIUrl":"https://doi.org/10.2174/0115733971355486250528163102","url":null,"abstract":"<p><strong>Background: </strong>Repetitive and heavy physical activities by agricultural workers can lead to the prevalence of musculoskeletal disorders and affect the quality of life of these individuals.</p><p><strong>Materials and methods: </strong>This cross-sectional study was conducted using cluster and convenience sampling on 259 agricultural workers employed in greenhouses in the City of Jiroft in southeastern Iran in the year 2024. Data were collected using the standardized Nordic Musculoskeletal Questionnaire and quality of life questionnaire, and analyzed using descriptive and inferential statistics such as mean, standard deviation, range, frequency, and percentage frequency. Independent t-test and regression were employed in SPSS-16 software at a significance level of 0.05 (p ≤ 0.05).</p><p><strong>Results: </strong>Among the 259 people studied, 120 (46.3%) had a low level and 139 (53.7%) had an average level of quality of life. The level of quality of life has a significant relationship with musculoskeletal disorders, occupation, and underlying disease. Based on this, people who do not have musculoskeletal problems have 2.84 times the chance of having a better quality of life than people who have these problems (95% CI 1.64, 4.94, p < 0.001). Additionally, greenhouse workers have a higher quality of life 2.21 times more than horticulture workers (95% CI 1.41, 4.15, p = 0.001). Furthermore, people without underlying disease have a higher quality of life 2.35 times than those with disease (95% CI 1.26, 4.39, p = 0.007).</p><p><strong>Conclusion: </strong>The quality of life of agricultural workers is low and moderate, and the prevalence of musculoskeletal disorders in workers has decreased the quality of life.</p>","PeriodicalId":11188,"journal":{"name":"Current rheumatology reviews","volume":" ","pages":""},"PeriodicalIF":1.2,"publicationDate":"2025-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144198460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}