2015 41st Annual Northeast Biomedical Engineering Conference (NEBEC)最新文献_第3页

Circumventing drug delivery problems in advanced pancreatic cancer treatment 规避晚期胰腺癌治疗中的药物输送问题

2015 41st Annual Northeast Biomedical Engineering Conference (NEBEC) Pub Date : 2015-04-17 DOI: 10.1109/NEBEC.2015.7117049

Lauren J Jablonowski, M. Wheatley

引用次数: 0

Development of scaffold for use in osteochondral tissue engineering 骨软骨组织工程用支架的研制

2015 41st Annual Northeast Biomedical Engineering Conference (NEBEC) Pub Date : 2015-04-17 DOI: 10.1109/NEBEC.2015.7117085

G. Clay, S. Modha, P. Schomacker, J. A. Cooper

引用次数: 0

Segmentation of spinal cord in the pediatric spinal Diffusion Tensor MR Imaging 小儿脊髓弥散张量磁共振成像中的脊髓分割

2015 41st Annual Northeast Biomedical Engineering Conference (NEBEC) Pub Date : 2015-04-17 DOI: 10.1109/NEBEC.2015.7117146

M. Alizadeh, F. Mohamed, S. Faro, P. Shah, D. Middleton, C. Conklin, M. Mulcahey

引用次数: 3

Bubble raft-an optical phantom for analyzing artifacts in OCT imaging of lung 气泡筏——用于分析肺部OCT成像伪影的光学幻影

2015 41st Annual Northeast Biomedical Engineering Conference (NEBEC) Pub Date : 2015-04-17 DOI: 10.1109/NEBEC.2015.7117200

Hanlin Tang, A. Gouldstone, C. DiMarzio

引用次数: 2

Methods for analysis of hemodynamic and metabolic risks factors in hypertension 高血压血流动力学及代谢危险因素分析方法

2015 41st Annual Northeast Biomedical Engineering Conference (NEBEC) Pub Date : 2015-04-17 DOI: 10.1109/NEBEC.2015.7117181

Priya Mohan, Timothy S. Phan, J. Li

{"title":"Methods for analysis of hemodynamic and metabolic risks factors in hypertension","authors":"Priya Mohan, Timothy S. Phan, J. Li","doi":"10.1109/NEBEC.2015.7117181","DOIUrl":"https://doi.org/10.1109/NEBEC.2015.7117181","url":null,"abstract":"Hypertension has its contribution from atherosclerosis or metabolic factors. It is commonly diagnosed with a sphygmomanometer (blood pressure cuff) which only outputs systolic (Ps) and diastolic (Pd) pressures. Hypertensive patients are then administered oral medication whose effect on arterial compliance (C), an index of vascular stiffness, cannot be accurately determined merely from Ps and Pd values. The underlying blood pressure waveforms are normally obtained clinically through catheterization. Vascular stiffness index (VSI) can then be computed from pulse waveform analysis (PWA). However, there are controversies as to whether a constant single-valued C alone is sufficient for assessing VSI. We investigated the time-varying, pressure-dependent characteristics of arterial compliance (C(P)) with a nonlinear model of the arterial system during normal, induced hypertension and vasodilator-treated conditions. Results show that C(P) differs from constant compliance C and that C(P) can rapidly reflect underlying beat-to-beat variations in arterial compliance and can effectively serve as a reliable index of VSI. It can be used for accurate evaluation of the efficacy of blood pressure altering drugs.","PeriodicalId":111398,"journal":{"name":"2015 41st Annual Northeast Biomedical Engineering Conference (NEBEC)","volume":"53 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127230561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Quantitative study on effects of baclofen on muscle spasticity in Multiple Sclerosis 巴氯芬对多发性硬化症肌肉痉挛影响的定量研究

2015 41st Annual Northeast Biomedical Engineering Conference (NEBEC) Pub Date : 2015-04-17 DOI: 10.1109/NEBEC.2015.7117076

T. Alter, W. Craelius, M. Wininger, M. Wallin, M. Moradi

{"title":"Quantitative study on effects of baclofen on muscle spasticity in Multiple Sclerosis","authors":"T. Alter, W. Craelius, M. Wininger, M. Wallin, M. Moradi","doi":"10.1109/NEBEC.2015.7117076","DOIUrl":"https://doi.org/10.1109/NEBEC.2015.7117076","url":null,"abstract":"Spasticity is clinically defined as velocity-dependent resistance to passive movement, characterized by excessive, jerky contraction of muscles. However, spasticity is not yet well understood, and current clinical measures of it are subjective and unreliable. We applied standard physics principles and phase space analyses to better visualize the motor impairments associated with spasticity in Multiple Sclerosis patients, at the VA Hospital in Washington, DC. Testing was conducted at baseline and then again after one month of de novo baclofen administration in order to determine whether this improved the patients' condition. Two analytical methods were used: (1) Phase Area Ratio (PAR) and (2) Spontaneous Accelerative Transients (SAT). The SAT analyses showed a small decrease in spasticity after baclofen use, while the PAR analyses and clinical measures showed no significant change. Although they provided differing results, this study shows that spasticity during active joint motions can be more reliably quantified through analytical methods. The PAR and SAT metrics may be applicable to a variety of physiological signals.","PeriodicalId":111398,"journal":{"name":"2015 41st Annual Northeast Biomedical Engineering Conference (NEBEC)","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130207222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Lachman's ACL test: A multibody simulation 拉赫曼前交叉韧带测试:多体模拟

2015 41st Annual Northeast Biomedical Engineering Conference (NEBEC) Pub Date : 2015-04-17 DOI: 10.1109/NEBEC.2015.7117159

J. Felice, M. Sebald, D. Piovesan, S. Bitticker

引用次数: 1

Synthetic micro-scale habitats emulating microbial system function 模拟微生物系统功能的合成微尺度生境

2015 41st Annual Northeast Biomedical Engineering Conference (NEBEC) Pub Date : 2015-04-17 DOI: 10.1109/NEBEC.2015.7117046

L. Shor

{"title":"Synthetic micro-scale habitats emulating microbial system function","authors":"L. Shor","doi":"10.1109/NEBEC.2015.7117046","DOIUrl":"https://doi.org/10.1109/NEBEC.2015.7117046","url":null,"abstract":"Summary form only given. Micro-scale habitat conditions control the composition and function of microbial communities. For example, the paunch of the eastern subterranean termite has a physical volume of just one microliter, yet is home to a complex community of bacteria, protists, archaea and fungi. Within the termite gut, steep gradients provide spatially-distinct microniches, while close proximity allows a metabolically diverse community to collaboratively convert a lignocellulosic feedstock into acetate and other useful products. Likewise, the function of the soil system emerges from the interactions of diverse microbes with various micro-structured habitats. Conventional bioengineering approaches cannot systematically replicate micro-scale features of real microbial habitats, and as a result, may fail to capture the complex or emergent properties of microbe-habitat systems. The Shor lab is developing synthetic micro-scale habitats with micro-scale physical structures, chemical gradients, and patchy microbial distributions characteristic of real microbe-habitat systems. Our synthetic micro-scale habitats are designed to implement advanced sensing, electro-chemical actuators, and molecular tools. We have shown microbially-secreted extracellular polymeric substances can regulate retention of soil moisture, but only in micro-structured settings. We have used microdevices with synthetic pore structures to accelerate the development of sustainable food production technology. Moving forward, there is a tremendous potential for engineered bio-physical systems to broaden the scope and accelerate the pace of bioengineering discovery. Applications include sustainable food and fuel production and better approaches to safeguard the environment and human health.","PeriodicalId":111398,"journal":{"name":"2015 41st Annual Northeast Biomedical Engineering Conference (NEBEC)","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-04-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121327087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Data-driven modeling of arterial wave propagation using non-invasive arterial pulse waveforms 利用非侵入性动脉脉冲波形进行动脉波传播的数据驱动建模

2015 41st Annual Northeast Biomedical Engineering Conference (NEBEC) Pub Date : 2015-04-17 DOI: 10.1109/NEBEC.2015.7117065

Z. Ghasemi, Jongchan Lee, Chang-Sei Kim, Hao-min Cheng, R. Mukkamala, J. Hahn

引用次数: 0

A wireless sensing system for continuous monitoring of intracompartmental pressures 一种连续监测室内压力的无线传感系统

2015 41st Annual Northeast Biomedical Engineering Conference (NEBEC) Pub Date : 2015-04-17 DOI: 10.1109/NEBEC.2015.7117098

James Z. Jackson, Matthew K. Dion, John F. Drazan, David A. Forsh, N. Cady, E. Ledet

引用次数: 0