Current Urology Reports最新文献

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Persistent Lower Urinary Tract Symptoms After BPH Surgery 良性前列腺增生手术后持续的下尿路症状
IF 2.6 2区 医学
Current Urology Reports Pub Date : 2024-04-05 DOI: 10.1007/s11934-024-01202-y
Joshua Heiman, William M. Snead, John Michael DiBianco
{"title":"Persistent Lower Urinary Tract Symptoms After BPH Surgery","authors":"Joshua Heiman, William M. Snead, John Michael DiBianco","doi":"10.1007/s11934-024-01202-y","DOIUrl":"https://doi.org/10.1007/s11934-024-01202-y","url":null,"abstract":"<h3 data-test=\"abstract-sub-heading\">Purpose of Review</h3><p>Lower urinary tract symptoms (LUTS) after surgical management for BPH pose a significant clinical challenge for urologists. Despite high success rates in relieving LUTS, there is a subset of patients who experience persistent symptoms after intervention. In this review article, we describe the management of patients with new or persistent LUTS after endoscopic bladder outlet surgery.</p><h3 data-test=\"abstract-sub-heading\">Recent Findings</h3><p>Previously, the goal for BPH management was to remove as much adenomatous tissue as possible. While potentially effective, this may lead to unwanted side effects. There has been a recent paradigm shift for new minimally invasive surgical therapies (MIST) that strategically treat adenomatous tissue, adding potential complexity in managing patients with new or residual symptoms in the postoperative setting.</p><h3 data-test=\"abstract-sub-heading\">Summary</h3><p>There is a paucity of literature to guide optimal workup and care of patients with persistent LUTS after surgical management. We characterize patients into distinct groups, defined by types of symptoms, irritative versus obstructive, and timing of the symptomatology, short term versus long term. By embracing this patient-centered approach with shared decision management, clinicians can optimize outcomes efficiently improving their patients’ quality of life.</p>","PeriodicalId":11112,"journal":{"name":"Current Urology Reports","volume":"8 1","pages":""},"PeriodicalIF":2.6,"publicationDate":"2024-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140573652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Adult Hypospadias Outcomes for the Pediatric Urologist. 成人尿道下裂对小儿泌尿科医生的影响。
IF 2.6 2区 医学
Current Urology Reports Pub Date : 2024-04-01 Epub Date: 2024-02-06 DOI: 10.1007/s11934-024-01196-7
Tyler Gaines, Jay Simhan
{"title":"Adult Hypospadias Outcomes for the Pediatric Urologist.","authors":"Tyler Gaines, Jay Simhan","doi":"10.1007/s11934-024-01196-7","DOIUrl":"10.1007/s11934-024-01196-7","url":null,"abstract":"<p><strong>Purpose of review: </strong>This review article will examine the current literature on hypospadias-related complications in adult patients.</p><p><strong>Recent findings: </strong>In this article, we will review the most recent studies evaluating hypospadias-related stricture disease, erectile function, fertility, and psychosexual outcomes in adult men with history of hypospadias repair in childhood. Managing hypospadias-related complications in adult patients is challenging to reconstructive urologists due to the compounded complexity of innate tissue deficiency and history of prior surgical repairs. In this review, we explore overall functional outcomes of adults with history of hypospadias repair as well as repair strategies of hypospadias-related urethral stricture disease. We will review erectile function, fertility and psychosexual outcomes as well as potential complications, which often do not surface until late adolescence and adulthood. Although it is challenging to characterize and quantify hypospadias-related complications, further longitudinal study is needed to better care for this complex patient population.</p>","PeriodicalId":11112,"journal":{"name":"Current Urology Reports","volume":" ","pages":"63-70"},"PeriodicalIF":2.6,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139691372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Laser Technology Advancements in the Treatment of Benign Prostatic Hypertrophy. 治疗良性前列腺肥大的激光技术进展。
IF 2.6 2区 医学
Current Urology Reports Pub Date : 2024-04-01 Epub Date: 2024-02-13 DOI: 10.1007/s11934-024-01197-6
David C Dalton, T Max Shelton, Marcelino Rivera
{"title":"Laser Technology Advancements in the Treatment of Benign Prostatic Hypertrophy.","authors":"David C Dalton, T Max Shelton, Marcelino Rivera","doi":"10.1007/s11934-024-01197-6","DOIUrl":"10.1007/s11934-024-01197-6","url":null,"abstract":"<p><strong>Purpose of review: </strong>Lasers have had a significant impact on the treatment of benign prostatic hypertrophy. This article attempts to distill the advancements in laser technology for the treatment of benign prostatic hypertrophy (BPH) into key and understandable points to help make this topic more accessible to urologists.</p><p><strong>Recent findings: </strong>The holmium:yttrium-aluminum-garnet (YAG) laser, one of the most significant lasers in the field of urology, has recently been improved with pulse modulating technology (Moses™ technology). New thulium:YAG technology allows both pulsed and continuous wave modes. The thulium fiber laser is one of the newer lasers to come to market and has been shown to have effective and safe outcomes. GreenLight™ lasers are predominantly used in photovaporization procedures and have also been studied extensively, although less in recent years. The modern urologist is fortunate to have many high-quality lasers and a wide variety of surgical techniques to choose from when treating BPH. Understanding the basic laser principles and applications will help urologists to select the best treatment options for their patients with BPH.</p>","PeriodicalId":11112,"journal":{"name":"Current Urology Reports","volume":" ","pages":"71-78"},"PeriodicalIF":2.6,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139722045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pediatric Robot-Assisted Laparoscopic Pyeloplasty: Where Are We Now? 小儿机器人辅助腹腔镜肾盂成形术:我们现在在哪里?
IF 2.6 2区 医学
Current Urology Reports Pub Date : 2024-03-01 Epub Date: 2024-02-07 DOI: 10.1007/s11934-024-01195-8
Suhaib Abdulfattah, Sameer Mittal
{"title":"Pediatric Robot-Assisted Laparoscopic Pyeloplasty: Where Are We Now?","authors":"Suhaib Abdulfattah, Sameer Mittal","doi":"10.1007/s11934-024-01195-8","DOIUrl":"10.1007/s11934-024-01195-8","url":null,"abstract":"<p><strong>Purpose of review: </strong>This review aims to provide an in-depth exploration of the recent advancements in robot-assisted laparoscopic pyeloplasty (RALP) and its evolving landscape in the context of infant pyeloplasty, complex genitourinary (GU) anatomy, recurrent ureteropelvic junction (UPJ) obstruction, cost considerations, and the learning curve.</p><p><strong>Recent findings: </strong>Recent literature highlights the safety and efficacy of RALP in treating the infant population, patients with complex GU anomalies, and recurrent UPJO which were all traditionally managed using the open approach. Cost considerations are evolving, with the potential for RALP to have a lesser financial burden. In addition, the learning curve for RALP is diminishing due to robust training programs and advances in research. RALP has become the gold standard in the treatment of UPJO in pediatric urology at many children's hospitals. Surgeon comfort and research in this space allow safe and successful reconstruction in the most challenging of cases.</p>","PeriodicalId":11112,"journal":{"name":"Current Urology Reports","volume":" ","pages":"55-61"},"PeriodicalIF":2.6,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139697129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Exploring the Ethical, Legal, and Social Implications of ChatGPT in Urology. 探讨ChatGPT在泌尿外科的伦理、法律和社会意义。
IF 2.6 2区 医学
Current Urology Reports Pub Date : 2024-01-01 Epub Date: 2023-09-22 DOI: 10.1007/s11934-023-01185-2
Kinju Adhikari, Nithesh Naik, Bm Zeeshan Hameed, S K Raghunath, Bhaskar K Somani
{"title":"Exploring the Ethical, Legal, and Social Implications of ChatGPT in Urology.","authors":"Kinju Adhikari, Nithesh Naik, Bm Zeeshan Hameed, S K Raghunath, Bhaskar K Somani","doi":"10.1007/s11934-023-01185-2","DOIUrl":"10.1007/s11934-023-01185-2","url":null,"abstract":"<p><strong>Purpose of the review: </strong>ChatGPT is programmed to generate responses based on pattern recognition. With this vast popularity and exponential growth, the question arises of moral issues, security and legitimacy. In this review article, we aim to analyze the ethical and legal implications of using ChatGPT in Urology and explore potential solutions addressing these concerns.</p><p><strong>Recent findings: </strong>There are many potential applications of ChatGPT in urology, and the extent to which it might improve healthcare may cause a profound shift in the way we deliver our services to patients and the overall healthcare system. This encompasses diagnosis and treatment planning, clinical workflow, patient education, augmenting consultations, and urological research. The ethical and legal considerations include patient autonomy and informed consent, privacy and confidentiality, bias and fairness, human oversight and accountability, trust and transparency, liability and malpractice, intellectual property rights, and regulatory framework. The application of ChatGPT in urology has shown great potential to improve patient care and assist urologists in various aspects of clinical practice, research, and education. Complying with data security and privacy regulations, and ensuring human oversight and accountability are some potential solutions to these legal and ethical concerns. Overall, the benefits and risks of using ChatGPT in urology must be weighed carefully, and a cautious approach must be taken to ensure that its use aligns with human values and advances patient care ethically and responsibly.</p>","PeriodicalId":11112,"journal":{"name":"Current Urology Reports","volume":" ","pages":"1-8"},"PeriodicalIF":2.6,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41115963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Potential of AI-Driven Chatbots in Urology: Revolutionizing Patient Care Through Artificial Intelligence. 人工智能驱动的聊天机器人在泌尿外科的潜力:通过人工智能彻底改变患者护理。
IF 2.6 2区 医学
Current Urology Reports Pub Date : 2024-01-01 Epub Date: 2023-09-19 DOI: 10.1007/s11934-023-01184-3
Ali Talyshinskii, Nithesh Naik, B M Zeeshan Hameed, Patrick Juliebø-Jones, Bhaskar Kumar Somani
{"title":"Potential of AI-Driven Chatbots in Urology: Revolutionizing Patient Care Through Artificial Intelligence.","authors":"Ali Talyshinskii, Nithesh Naik, B M Zeeshan Hameed, Patrick Juliebø-Jones, Bhaskar Kumar Somani","doi":"10.1007/s11934-023-01184-3","DOIUrl":"10.1007/s11934-023-01184-3","url":null,"abstract":"<p><strong>Purpose of review: </strong>Artificial intelligence (AI) chatbots have emerged as a potential tool to transform urology by improving patient care and physician efficiency. With an emphasis on their potential advantages and drawbacks, this literature review offers a thorough assessment of the state of AI-driven chatbots in urology today.</p><p><strong>Recent findings: </strong>The capacity of AI-driven chatbots in urology to give patients individualized and timely medical advice is one of its key advantages. Chatbots can help patients prioritize their symptoms and give advice on the best course of treatment. By automating administrative duties and offering clinical decision support, chatbots can also help healthcare providers. Before chatbots are widely used in urology, there are a few issues that need to be resolved. The precision of chatbot diagnoses and recommendations might be impacted by technical constraints like system errors and flaws. Additionally, issues regarding the security and privacy of patient data must be resolved, and chatbots must adhere to all applicable laws. Important issues that must be addressed include accuracy and dependability because any mistakes or inaccuracies could seriously harm patients. The final obstacle is resistance from patients and healthcare professionals who are hesitant to use new technology or who value in-person encounters. AI-driven chatbots have the potential to significantly improve urology care and efficiency. However, it is essential to thoroughly test and ensure the accuracy of chatbots, address privacy and security concerns, and design user-friendly chatbots that can integrate into existing workflows. By exploring various scenarios and examining the current literature, this review provides an analysis of the prospects and limitations of implementing chatbots in urology.</p>","PeriodicalId":11112,"journal":{"name":"Current Urology Reports","volume":" ","pages":"9-18"},"PeriodicalIF":2.6,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10787686/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10309936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Reconstruction Techniques After Partial Nephrectomy: Classic vs. Sutureless Approach—A Narrative Review 肾部分切除术后的重建技术:经典方法与无缝线方法--叙述性回顾
IF 2.6 2区 医学
Current Urology Reports Pub Date : 2023-12-29 DOI: 10.1007/s11934-023-01194-1
J. C. Moreno Cortés, J. González García, J. Caño Velasco, J. Aragón Chamizo, D. Subirá Rios
{"title":"Reconstruction Techniques After Partial Nephrectomy: Classic vs. Sutureless Approach—A Narrative Review","authors":"J. C. Moreno Cortés, J. González García, J. Caño Velasco, J. Aragón Chamizo, D. Subirá Rios","doi":"10.1007/s11934-023-01194-1","DOIUrl":"https://doi.org/10.1007/s11934-023-01194-1","url":null,"abstract":"<h3 data-test=\"abstract-sub-heading\">Purpose of Review</h3><p>The purpose of this review is to update the information about the different types of reconstruction after partial nephrectomy, with special emphasis on the new methods of suture-free hemostasis currently available.</p><h3 data-test=\"abstract-sub-heading\">Recent Findings</h3><p>The aim of renal reconstruction is to avoid bleeding and leakage of the collecting system, but now the renorrhaphy technique used is considered one of the modifiable determinants of renal function after surgery. In an attempt to avoid the loss of renal function implicit in classic reconstruction, new techniques have been described to control hemostasis and urinary leakage, which employ fewer suture layers, different suture materials and designs, and a wide range of commercially available hemostatic materials.</p><h3 data-test=\"abstract-sub-heading\">Summary</h3><p>Multiple suture characteristics have been studied as a potential factor influencing the renal function observed after partial nephrectomy. Single-plane suture techniques, the use of bearded sutures, and running sutures seem to be associated with less deterioration in postoperative renal function, and deep medullary sutures should be avoided to avoid affecting the arcuate arteries. Sutureless hemostasis systems could prevent the deterioration of renal function and complications derived from suturing, also reducing ischemia time and surgical time without increasing the risk of complications.</p>","PeriodicalId":11112,"journal":{"name":"Current Urology Reports","volume":"2 1","pages":""},"PeriodicalIF":2.6,"publicationDate":"2023-12-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139062374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Smart Diagnosis of Urinary Tract Infections: is Artificial Intelligence the Fast-Lane Solution? 尿路感染的智能诊断:人工智能是快速解决方案吗?
IF 2.6 2区 医学
Current Urology Reports Pub Date : 2023-12-19 DOI: 10.1007/s11934-023-01192-3
Nithesh Naik, Ali Talyshinskii, Dasharathraj K. Shetty, B. M. Zeeshan Hameed, Rano Zhankina, Bhaskar K. Somani
{"title":"Smart Diagnosis of Urinary Tract Infections: is Artificial Intelligence the Fast-Lane Solution?","authors":"Nithesh Naik, Ali Talyshinskii, Dasharathraj K. Shetty, B. M. Zeeshan Hameed, Rano Zhankina, Bhaskar K. Somani","doi":"10.1007/s11934-023-01192-3","DOIUrl":"https://doi.org/10.1007/s11934-023-01192-3","url":null,"abstract":"<h3 data-test=\"abstract-sub-heading\">Purpose of Review</h3><p>Artificial intelligence (AI) can significantly improve physicians’ workflow when examining patients with UTI. However, most contemporary reviews are focused on examining the usage of AI with a restricted quantity of data, analyzing only a subset of AI algorithms, or performing narrative work without analyzing all dedicated studies. Given the preceding, the goal of this work was to conduct a mini-review to determine the current state of AI-based systems as a support in UTI diagnosis.</p><h3 data-test=\"abstract-sub-heading\">Recent Findings</h3><p>There are sufficient publications to comprehend the potential applications of artificial intelligence in the diagnosis of UTIs. Existing research in this field, in general, publishes performance metrics that are exemplary. However, upon closer inspection, many of the available publications are burdened with flaws associated with the improper use of artificial intelligence, such as the use of a small number of samples, their lack of heterogeneity, and the absence of external validation. AI-based models cannot be classified as full-fledged physician assistants in diagnosing UTIs due to the fact that these limitations and flaws represent only a portion of all potential obstacles. Instead, such studies should be evaluated as exploratory, with a focus on the importance of future work that complies with all rules governing the use of AI.</p><h3 data-test=\"abstract-sub-heading\">Summary</h3><p>AI algorithms have demonstrated their potential for UTI diagnosis. However, further studies utilizing large, heterogeneous, prospectively collected datasets, as well as external validations, are required to define the actual clinical workflow value of artificial intelligence.</p>","PeriodicalId":11112,"journal":{"name":"Current Urology Reports","volume":"14 1","pages":""},"PeriodicalIF":2.6,"publicationDate":"2023-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138742666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessment of Prostate and Bladder Cancer Genomic Biomarkers Using Artificial Intelligence: a Systematic Review 利用人工智能评估前列腺癌和膀胱癌基因组生物标记物:系统综述
IF 2.6 2区 医学
Current Urology Reports Pub Date : 2023-12-15 DOI: 10.1007/s11934-023-01193-2
Andrey Bazarkin, Andrey Morozov, Alexander Androsov, Harun Fajkovic, Juan Gomez Rivas, Nirmish Singla, Svetlana Koroleva, Jeremy Yuen-Chun Teoh, Andrei V. Zvyagin, Shahrokh François Shariat, Bhaskar Somani, Dmitry Enikeev
{"title":"Assessment of Prostate and Bladder Cancer Genomic Biomarkers Using Artificial Intelligence: a Systematic Review","authors":"Andrey Bazarkin, Andrey Morozov, Alexander Androsov, Harun Fajkovic, Juan Gomez Rivas, Nirmish Singla, Svetlana Koroleva, Jeremy Yuen-Chun Teoh, Andrei V. Zvyagin, Shahrokh François Shariat, Bhaskar Somani, Dmitry Enikeev","doi":"10.1007/s11934-023-01193-2","DOIUrl":"https://doi.org/10.1007/s11934-023-01193-2","url":null,"abstract":"<h3 data-test=\"abstract-sub-heading\">Purpose of Review</h3><p>The aim of the systematic review is to assess AI’s capabilities in the genetics of prostate cancer (PCa) and bladder cancer (BCa) to evaluate target groups for such analysis as well as to assess its prospects in daily practice.</p><h3 data-test=\"abstract-sub-heading\">Recent Findings</h3><p>In total, our analysis included 27 articles: 10 articles have reported on PCa and 17 on BCa, respectively. The AI algorithms added clinical value and demonstrated promising results in several fields, including cancer detection, assessment of cancer development risk, risk stratification in terms of survival and relapse, and prediction of response to a specific therapy. Besides clinical applications, genetic analysis aided by the AI shed light on the basic urologic cancer biology. We believe, our results of the AI application to the analysis of PCa, BCa data sets will help to identify new targets for urological cancer therapy.</p><h3 data-test=\"abstract-sub-heading\">Summary</h3><p>The integration of AI in genomic research for screening and clinical applications will evolve with time to help personalizing chemotherapy, prediction of survival and relapse, aid treatment strategies such as reducing frequency of diagnostic cystoscopies, and clinical decision support, e.g., by predicting immunotherapy response. These factors will ultimately lead to personalized and precision medicine thereby improving patient outcomes.</p>","PeriodicalId":11112,"journal":{"name":"Current Urology Reports","volume":"2 1","pages":""},"PeriodicalIF":2.6,"publicationDate":"2023-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138692106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Overview of Benchtop Models for Comparison of Surgical Treatments for Benign Prostatic Hyperplasia. 用于比较良性前列腺增生手术治疗的Benchtop模型综述。
IF 2.6 2区 医学
Current Urology Reports Pub Date : 2023-12-01 Epub Date: 2023-11-09 DOI: 10.1007/s11934-023-01189-y
Kevin Birdsall, Ricardo R Gonzalez
{"title":"Overview of Benchtop Models for Comparison of Surgical Treatments for Benign Prostatic Hyperplasia.","authors":"Kevin Birdsall, Ricardo R Gonzalez","doi":"10.1007/s11934-023-01189-y","DOIUrl":"10.1007/s11934-023-01189-y","url":null,"abstract":"<p><strong>Purpose of review: </strong>Benign prostatic hyperplasia (BPH) is a disease of the lower urinary tract which often requires surgical treatment. Recently, there has been a deluge of new treatment options, rarely validated or compared to current treatments on a benchtop model. The purpose of this review is to examine the literature and report which benchtop models are currently being used, which therapies have been tested on them, and what outcomes are being studied on each model.</p><p><strong>Recent findings: </strong>There are various benchtop models to choose from, each with their unique benefits and drawbacks. Perfused porcine kidney models are used to assess bleeding on the benchtop, ex-vivo human prostate helps to see specific interactions of devices with the prostatic tissue, and all other models have evaluated tissue ablation rates and depth of coagulation. There are currently no synthetic or non-animal tissues being used for this purpose, and surgical techniques such as enucleation, water-jet ablation, prostate stents, and water vapor thermal therapy have no representation in these benchtop tests. Benchtop testing serves an important role in the evaluation and comparison of surgical treatments for BPH. This testing allows these therapies to be objectively compared to one another, helping novel medical devices in their path to market and urologists make treatment decisions. Future directions may include further validation of the animal models currently being used and development of synthetic models which mimic the prostate on the benchtop.</p>","PeriodicalId":11112,"journal":{"name":"Current Urology Reports","volume":" ","pages":"571-577"},"PeriodicalIF":2.6,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71520786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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