Current Urology Reports最新文献_第4页

Risk Factors and Contemporary Management Options for Pain and Discomfort Experienced During a Prostate Biopsy. 前列腺活检过程中出现疼痛和不适的风险因素和现代处理方案。

IF 2.5 2区医学

Current Urology Reports Pub Date : 2024-10-01 Epub Date: 2024-06-19 DOI: 10.1007/s11934-024-01220-w

Gabriela M Diaz, Lindsey T Webb, Maximilian J Rabil, Soum D Lokeshwar, Ankur U Choksi, Michael S Leapman, Preston C Sprenkle

{"title":"Risk Factors and Contemporary Management Options for Pain and Discomfort Experienced During a Prostate Biopsy.","authors":"Gabriela M Diaz, Lindsey T Webb, Maximilian J Rabil, Soum D Lokeshwar, Ankur U Choksi, Michael S Leapman, Preston C Sprenkle","doi":"10.1007/s11934-024-01220-w","DOIUrl":"10.1007/s11934-024-01220-w","url":null,"abstract":"Purpose of review: Prostate fusion biopsy, an innovative imaging modality for diagnosing prostate cancer, presents certain challenges for patients including discomfort and emotional distress, leading to nonadherence to treatment and follow-ups. To inform clinicians and offer pain relief alternatives to patients, this review delves into the risk factors for increased pain and modern management options to alleviate pain during prostate biopsy.Recent findings: Individual responses to pain vary, and the overall experience of pain during a prostate biopsy has been contributed to numerous factors such as patient age, prostate volume, previous biopsy experience, and more. As a result, several strategies aim to mitigate pain during in-office procedures. Notably, techniques including pharmacological analgesics, hand holding, heating pads, entertainment/virtual reality, and distraction have shown significant efficacy. Existing studies explore risk factors influencing pain intensity during prostate biopsy and effective pain management strategies. This review consolidates available information to guide clinicians in enhancing patient comfort and thus, encourage surveillance adherence.","PeriodicalId":11112,"journal":{"name":"Current Urology Reports","volume":" ","pages":"243-252"},"PeriodicalIF":2.5,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141418265","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Role of Transurethral BPH Surgeries in Management of Urinary Symptoms in Prostate Cancer Patients, Narrative Review. 经尿道前列腺增生手术在治疗前列腺癌患者尿路症状中的作用，叙述性综述。

IF 2.5 2区医学

Current Urology Reports Pub Date : 2024-10-01 DOI: 10.1007/s11934-024-01229-1

Mohamed Elsaqa, Marawan M El Tayeb

{"title":"The Role of Transurethral BPH Surgeries in Management of Urinary Symptoms in Prostate Cancer Patients, Narrative Review.","authors":"Mohamed Elsaqa, Marawan M El Tayeb","doi":"10.1007/s11934-024-01229-1","DOIUrl":"10.1007/s11934-024-01229-1","url":null,"abstract":"Purpose of review: Prostate cancer and benign prostate hyperplasia (BPH) are two ubiquitous pathologies that may coexist. A significant percentage of patients with different stages of prostate cancer suffer lower urinary tract symptoms (LUTS) due to associated BPH. We aimed to review the literature regarding the role of transurethral surgeries in the management of prostate cancer patients and the different available management options.Recent findings: The evidence in literature for the use of BPH surgeries in prostate cancer patients is based mainly on low-quality retrospective studies. In patients on active surveillance, BPH surgeries are beneficial in relieving LUTS without oncological risk and can eliminate the contribution of adenoma to PSA level. In patients with advanced prostate cancer, palliative BPH surgery can relieve LUTS and urinary retention with unclear oncological impact; however some reports depict that the need for BPH surgery in advanced prostate cancer is associated with poorer prognosis. In patients receiving radiotherapy, various studies showed that transurethral resection of prostate (TURP) is associated with increased radiotoxicity despite some recent reports encouraging the use of Holmium Laser Enucleation of the Prostate (HoLEP) to improve urinary symptom scores before radiotherapy. The most commonly reported techniques utilized are TURP, photoselective vaporization of prostate (PVP) and HoLEP. The use of BPH surgery is justified for relieving LUTS in selected prostate cancer patients on active surveillance or in advanced stages, however the use in the pre-radiotherapy settings remains controversial. Future prospective and randomized controlled trials are required for validating the benefits and assessing potential hazards.","PeriodicalId":11112,"journal":{"name":"Current Urology Reports","volume":"26 1","pages":"7"},"PeriodicalIF":2.5,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11445351/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142343374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Genomics in active surveillance and post-prostatectomy patients: A review of when and how to use effectively. 主动监测和前列腺切除术后患者的基因组学：回顾何时以及如何有效使用。

IF 2.5 2区医学

Current Urology Reports Pub Date : 2024-10-01 Epub Date: 2024-06-13 DOI: 10.1007/s11934-024-01219-3

Adedayo Adetunji, Nikit Venishetty, Nita Gombakomba, Karl-Ray Jeune, Matthew Smith, Andrew Winer

{"title":"Genomics in active surveillance and post-prostatectomy patients: A review of when and how to use effectively.","authors":"Adedayo Adetunji, Nikit Venishetty, Nita Gombakomba, Karl-Ray Jeune, Matthew Smith, Andrew Winer","doi":"10.1007/s11934-024-01219-3","DOIUrl":"10.1007/s11934-024-01219-3","url":null,"abstract":"Purpose of review: Prostate cancer (PCa) represents a significant health burden globally, ranking as the most diagnosed cancer among men and a leading cause of cancer-related mortality. Conventional treatment methods such as radiation therapy or radical prostatectomy have significant side effects which often impact quality of life. As our understanding of the natural history and progression of PCa has evolved, so has the evolution of management options.Recent findings: Active surveillance (AS) has become an increasingly favored approach to the management of very low, low, and properly selected favorable intermediate risk PCa. AS permits ongoing observation and postpones intervention until definitive treatment is required. There are, however, challenges with selecting patients for AS, which further emphasizes the need for more precise tools to better risk stratify patients and choose candidates more accurately. Tissue-based biomarkers, such as ProMark, Prolaris, GPS (formerly Oncotype DX), and Decipher, are valuable because they improve the accuracy of patient selection for AS and offer important information on the prognosis and severity of disease. By enabling patients to be categorized according to their risk profiles, these biomarkers help physicians and patients make better informed treatment choices and lower the possibility of overtreatment. Even with their potential, further standardization and validation of these biomarkers is required to guarantee their broad clinical utility. Active surveillance has emerged as a preferred strategy for managing low-risk prostate cancer, and tissue-based biomarkers play a crucial role in refining patient selection and risk stratification. Standardization and validation of these biomarkers are essential to ensure their widespread clinical use and optimize patient outcomes.","PeriodicalId":11112,"journal":{"name":"Current Urology Reports","volume":" ","pages":"253-260"},"PeriodicalIF":2.5,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141310317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Preference Signaling in the Urology Match. 泌尿外科比赛中的偏好信号传递。

IF 2.5 2区医学

Current Urology Reports Pub Date : 2024-10-01 Epub Date: 2024-06-29 DOI: 10.1007/s11934-024-01210-y

Erica Traxel, Simone Thavaseelan

引用次数: 0

Management Strategies for Patients with Non-Infectious Cystitis: A Review of the Literature. 非感染性膀胱炎患者的管理策略：文献综述。

IF 2.5 2区医学

Current Urology Reports Pub Date : 2024-09-30 DOI: 10.1007/s11934-024-01236-2

Jawad Aqeel, Kathryn Sawyer, Yu Zheng, Priyanka Gupta

{"title":"Management Strategies for Patients with Non-Infectious Cystitis: A Review of the Literature.","authors":"Jawad Aqeel, Kathryn Sawyer, Yu Zheng, Priyanka Gupta","doi":"10.1007/s11934-024-01236-2","DOIUrl":"https://doi.org/10.1007/s11934-024-01236-2","url":null,"abstract":"Purpose of review: The management of noninfectious cystitis continues to evolve as new treatments continue to be developed and investigated. This review aims to synthesize the most recent data regarding management strategies for noninfectious cystitis focused on non-ulcerative, ulcerative, eosinophilic, and ketamine-induced cystitis.Recent findings: Several novel treatments have shown promise as management options including combination antihistamine therapy, phosphodiesterase 5 inhibitors, alpha lipoic acid supplements, and onabotulinumtoxin A. Recent studies have also found pentosan polysulfate sodium to have adverse ophthalmologic effects. For patients with ulcerative cystitis, recent research has shown that fulguration with or without triamcinolone injections should not be delayed. The treatment of noninfectious cystitis should be patient specific based on factors including etiology and symptom profile. Multimodal regimens are often the most effective. Treatment should be started with conservative options and escalated as necessary to oral treatments, intravesical options, or procedural management.","PeriodicalId":11112,"journal":{"name":"Current Urology Reports","volume":"26 1","pages":"6"},"PeriodicalIF":2.5,"publicationDate":"2024-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142343372","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nutritional Aspects of Spina Bifida Care: Optimizing Medical Management and Surgical Healing. 脊柱裂护理的营养问题：优化医疗管理和手术愈合。

IF 2.5 2区医学

Current Urology Reports Pub Date : 2024-09-30 DOI: 10.1007/s11934-024-01230-8

Anne G Dudley

引用次数: 0

AI for BPH Surgical Decision-Making: Cost Effectiveness and Outcomes. 用于良性前列腺增生手术决策的人工智能：成本效益与结果。

IF 2.5 2区医学

Current Urology Reports Pub Date : 2024-09-23 DOI: 10.1007/s11934-024-01240-6

John Lama, Joshua Winograd, Alia Codelia-Anjum, Naeem Bhojani, Dean Elterman, Kevin C Zorn, Bilal Chughtai

{"title":"AI for BPH Surgical Decision-Making: Cost Effectiveness and Outcomes.","authors":"John Lama, Joshua Winograd, Alia Codelia-Anjum, Naeem Bhojani, Dean Elterman, Kevin C Zorn, Bilal Chughtai","doi":"10.1007/s11934-024-01240-6","DOIUrl":"https://doi.org/10.1007/s11934-024-01240-6","url":null,"abstract":"Purpose of review: Benign prostatic hyperplasia (BPH) is prevalent in nearly 70% of men over the age of 60, leading to significant clinical challenges due to varying symptom presentations and treatment responses. The decision to undergo surgical intervention is not straightforward; the American Urological Association recommends consideration of surgical treatment after inadequate or failed response to medical therapy. This review explores the role of artificial intelligence (AI), including machine learning and deep learning models, in enhancing the decision-making processes for BPH management.Recent findings: AI applications in this space include analysis of non-invasive imaging modalities, such as multiparametric Magnetic Resonance Imaging (MRI) and Ultrasound, which enhance diagnostic precision. AI models also concatenate serum biomarkers and histopathological analysis to distinguish BPH from prostate cancer (PC), offering high accuracy rates. Furthermore, AI aids in predicting patient outcomes post-treatment, supporting personalized medicine, and optimizing therapeutic strategies. AI has demonstrated potential in differentiating BPH from PC through advanced imaging and predictive models, improving diagnostic accuracy, and reducing the need for invasive procedures. Despite promising advancements, challenges remain in integrating AI into clinical workflows, establishing standard evaluation metrics, and achieving cost-effectiveness. Here, we underscore the potential of AI to improve patient outcomes, streamline BPH management, and reduce healthcare costs, especially with continued research and development in this transformative field.","PeriodicalId":11112,"journal":{"name":"Current Urology Reports","volume":"26 1","pages":"4"},"PeriodicalIF":2.5,"publicationDate":"2024-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142281795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Promise of Artificial Intelligence in Peyronie's Disease. 人工智能在佩罗尼氏病中的前景。

IF 2.5 2区医学

Current Urology Reports Pub Date : 2024-09-21 DOI: 10.1007/s11934-024-01233-5

Thiago P Furtado, Vadim Osadchiy, Sriram V Eleswarapu

引用次数: 0

The Emerging Role of Artificial Intelligence and Automated Platforms for the Assessment of Penile Curvature: A Scoping Review. 人工智能和自动平台在阴茎弯曲度评估中的新兴作用：范围综述》。

IF 2.5 2区医学

Current Urology Reports Pub Date : 2024-09-20 DOI: 10.1007/s11934-024-01232-6

Kieran Lewis, Lydia DeAngelo, Omer Raheem, Raevti Bole

{"title":"The Emerging Role of Artificial Intelligence and Automated Platforms for the Assessment of Penile Curvature: A Scoping Review.","authors":"Kieran Lewis, Lydia DeAngelo, Omer Raheem, Raevti Bole","doi":"10.1007/s11934-024-01232-6","DOIUrl":"10.1007/s11934-024-01232-6","url":null,"abstract":"Purpose of the review: The estimation of penile curvature is an essential component in the assessment of both Peyronie's disease and hypospadias-associated congenital penile curvature, as the degree of curvature can significantly impact treatment decision-making. However, there is a lack of standardization in curvature assessment and current methodologies are prone to inaccuracies. With the rise of artificial intelligence (AI) in urology, new research has explored its applications in penile curvature assessment. This review aims to evaluate the current uses of AI and other automated platforms for assessing penile curvature.Recent findings: Several novel and promising tools have been developed to estimate penile curvature, some utilizing AI-driven models and others employing automated computational models. These platforms aim to improve curvature assessment in various settings, including at-home evaluation of Peyronie's disease, in-office assessments using three-dimensional (3D) methodologies, and preoperative evaluations for hypospadias repair. In general, these new platforms produce highly accurate and reproducible angle estimates in non-clinical studies, however their effectiveness and relation to patient outcomes has had limited evaluation in clinical settings. Significant advancements have been made in the assessment and estimation of penile curvature in both Peyronie's and pediatric patients, largely driven by AI and other automated platforms. Continued research is needed to validate these findings in clinical studies, confirm their efficacy, and assess their feasibility for real-world applications.","PeriodicalId":11112,"journal":{"name":"Current Urology Reports","volume":"26 1","pages":"2"},"PeriodicalIF":2.5,"publicationDate":"2024-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11415446/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142281729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Advancements in Understanding and Managing Radiation Cystitis: A Comprehensive Review 了解和治疗放射性膀胱炎的进展：全面回顾

IF 2.6 2区医学

Current Urology Reports Pub Date : 2024-09-17 DOI: 10.1007/s11934-024-01238-0

Emily Neckonoff, Christopher B. Anderson

{"title":"Advancements in Understanding and Managing Radiation Cystitis: A Comprehensive Review","authors":"Emily Neckonoff, Christopher B. Anderson","doi":"10.1007/s11934-024-01238-0","DOIUrl":"https://doi.org/10.1007/s11934-024-01238-0","url":null,"abstract":"<h3 data-test=\"abstract-sub-heading\">Purpose of Review</h3>This manuscript aims to provide a comprehensive overview of the pathophysiology, risk factors, prevention strategies, and management options for radiation cystitis.<h3 data-test=\"abstract-sub-heading\">Recent Findings</h3>Recent studies have shed light on the pathophysiology of radiation cystitis, highlighting the role of inflammation, fibrosis, and vascular damage. Emerging preventive measures like stem cell therapy offer promise, alongside novel treatments such as amniotic bladder therapy and hyperbaric oxygen therapy.<h3 data-test=\"abstract-sub-heading\">Summary</h3>This review outlines the latest research on radiation cystitis, covering its pathophysiology, risk factors, prevention, and management. Major findings include insights into the mechanisms of RC development, promising preventive and therapeutic approaches, and the importance of standardized treatment pathways. Future research should focus on identifying genetic risk factors, improving treatment efficacy, and enhancing patient outcomes. This review offers valuable insights for clinicians and researchers, guiding future investigations into radiation cystitis management.","PeriodicalId":11112,"journal":{"name":"Current Urology Reports","volume":"21 1","pages":""},"PeriodicalIF":2.6,"publicationDate":"2024-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142267674","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0