Current Urology Reports最新文献

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Advancements in Understanding and Managing Radiation Cystitis: A Comprehensive Review 了解和治疗放射性膀胱炎的进展:全面回顾
IF 2.6 2区 医学
Current Urology Reports Pub Date : 2024-09-17 DOI: 10.1007/s11934-024-01238-0
Emily Neckonoff, Christopher B. Anderson
{"title":"Advancements in Understanding and Managing Radiation Cystitis: A Comprehensive Review","authors":"Emily Neckonoff, Christopher B. Anderson","doi":"10.1007/s11934-024-01238-0","DOIUrl":"https://doi.org/10.1007/s11934-024-01238-0","url":null,"abstract":"<h3 data-test=\"abstract-sub-heading\">Purpose of Review</h3><p>This manuscript aims to provide a comprehensive overview of the pathophysiology, risk factors, prevention strategies, and management options for radiation cystitis.</p><h3 data-test=\"abstract-sub-heading\">Recent Findings</h3><p>Recent studies have shed light on the pathophysiology of radiation cystitis, highlighting the role of inflammation, fibrosis, and vascular damage. Emerging preventive measures like stem cell therapy offer promise, alongside novel treatments such as amniotic bladder therapy and hyperbaric oxygen therapy.</p><h3 data-test=\"abstract-sub-heading\">Summary</h3><p>This review outlines the latest research on radiation cystitis, covering its pathophysiology, risk factors, prevention, and management. Major findings include insights into the mechanisms of RC development, promising preventive and therapeutic approaches, and the importance of standardized treatment pathways. Future research should focus on identifying genetic risk factors, improving treatment efficacy, and enhancing patient outcomes. This review offers valuable insights for clinicians and researchers, guiding future investigations into radiation cystitis management.</p>","PeriodicalId":11112,"journal":{"name":"Current Urology Reports","volume":"21 1","pages":""},"PeriodicalIF":2.6,"publicationDate":"2024-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142267674","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Extended Utilization of Bulking Agents in Pediatric Urology. 在小儿泌尿外科中扩大使用增容剂。
IF 2.5 2区 医学
Current Urology Reports Pub Date : 2024-09-01 Epub Date: 2024-06-18 DOI: 10.1007/s11934-024-01212-w
Corey Weinstein, Andrew Kirsch
{"title":"The Extended Utilization of Bulking Agents in Pediatric Urology.","authors":"Corey Weinstein, Andrew Kirsch","doi":"10.1007/s11934-024-01212-w","DOIUrl":"10.1007/s11934-024-01212-w","url":null,"abstract":"<p><strong>Purpose of review: </strong>Traditional surgical management for urinary incontinence and vesicoureteral reflux often requires complex reconstructive surgery and extended hospitalizations. Since the introduction of endoscopic bulking agents in 1973, there has been increasing interest in the use of endoscopic injection (EI) and bulking for the treatment of a variety of pediatric urologic disorders. The purpose of this review is to summarize the most recent literature addressing the use of bulking agents in pediatric urology.</p><p><strong>Recent findings: </strong>The most recent literature has focused primarily on the use of EI of bulking agents at the bladder neck for the treatment of urinary incontinence. Other uses of EI of bulking agents has focused on the treatment of vesicoureteral reflux (VUR) in patients with anatomic abnormalities or treatment of incontinence catheterizable channels. The development of advanced techniques for endoscopic injection along with safe, stable bulking agents has allowed for the treatment of a variety of urologic conditions. This minimally invasive procedure offers an additional tool for the pediatric urologist's armamentarium in the treatment of urinary incontinence and VUR.</p>","PeriodicalId":11112,"journal":{"name":"Current Urology Reports","volume":" ","pages":"233-239"},"PeriodicalIF":2.5,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141418266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Virtual Urology Residency Interviews in the Post-Pandemic Era. 后流行病时代的虚拟泌尿科住院医师面试。
IF 2.5 2区 医学
Current Urology Reports Pub Date : 2024-09-01 Epub Date: 2024-07-10 DOI: 10.1007/s11934-024-01215-7
Sakina Z Neemuchwala, Gary E Lemack
{"title":"Virtual Urology Residency Interviews in the Post-Pandemic Era.","authors":"Sakina Z Neemuchwala, Gary E Lemack","doi":"10.1007/s11934-024-01215-7","DOIUrl":"10.1007/s11934-024-01215-7","url":null,"abstract":"<p><strong>Purpose of review: </strong>Urology programs are considering maintaining the virtual format for residency interviews after COVID-19. This article explores the benefits and possible risks of this decision, as well as ways the application process can be improved.</p><p><strong>Recent findings: </strong>Virtual interviews save students and programs time and money, attracting a more diverse pool of applicants. Most applicants believe that faculty interviews are well replicated virtually; however, it is difficult to represent the culture of the program and city. Program directors are concerned about adequate evaluation of applicants virtually. There is also concern of over-application by candidates and inequities surrounding away rotations. Virtual interviews have become mandated in Urology over the last several years, with some notable benefits. Ongoing analysis of the advantages, and potential threats, of this policy is essential to developing an equitable and functional interview process for students and programs alike, in the post-pandemic era.</p>","PeriodicalId":11112,"journal":{"name":"Current Urology Reports","volume":" ","pages":"201-205"},"PeriodicalIF":2.5,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141579187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Erectile Dysfunction in Adolescents and Young Adults. 青少年和年轻人的勃起功能障碍。
IF 2.5 2区 医学
Current Urology Reports Pub Date : 2024-09-01 Epub Date: 2024-06-26 DOI: 10.1007/s11934-024-01213-9
Amelia Pantazis, Israel Franco, Jordan Gitlin
{"title":"Erectile Dysfunction in Adolescents and Young Adults.","authors":"Amelia Pantazis, Israel Franco, Jordan Gitlin","doi":"10.1007/s11934-024-01213-9","DOIUrl":"10.1007/s11934-024-01213-9","url":null,"abstract":"<p><strong>Purpose of review: </strong>The goal of this paper is to provide a summary of the recent research, evaluation, work-up, and treatment recommendations regarding erectile dysfunction in adolescents and young adults to better equip pediatric urologists to manage patients with this condition.</p><p><strong>Recent findings: </strong>The latest research regarding erectile dysfunction in this population includes organic and psychogenic etiologies, correlations between the COVID-19 pandemic, and online pornography consumption. In our large pediatric urology practice, we found an 31x increase of adolescent males presenting with erectile dysfunction since 2014. The majority of cases are attributed to a psychogenic etiology such as anxiety or depression. It is likely that with stress from anxiety and depression, cortisol levels rise, increasing vascular resistance and leading erectile dysfunction in this population. Most patients want to be reassured of normal testosterone levels, offered cognitive behavioral therapy, and be rehabilitated with tadalafil starting at 5 mg p.o. daily until tapered.</p>","PeriodicalId":11112,"journal":{"name":"Current Urology Reports","volume":" ","pages":"225-232"},"PeriodicalIF":2.5,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141450037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Financial and Business Literacy Among Urology Residents: Is this a Problem and How Can We Better Prepare Residents for their Careers? 泌尿外科住院医师的财务和商业知识:这是一个问题吗?我们如何才能更好地为住院医生的职业生涯做好准备?
IF 2.5 2区 医学
Current Urology Reports Pub Date : 2024-09-01 Epub Date: 2024-06-21 DOI: 10.1007/s11934-024-01216-6
Vinayak Madhusoodanan, Joshua Bitran, Maxwell Towe, Chad Ritch
{"title":"Financial and Business Literacy Among Urology Residents: Is this a Problem and How Can We Better Prepare Residents for their Careers?","authors":"Vinayak Madhusoodanan, Joshua Bitran, Maxwell Towe, Chad Ritch","doi":"10.1007/s11934-024-01216-6","DOIUrl":"10.1007/s11934-024-01216-6","url":null,"abstract":"<p><strong>Purpose of review: </strong>Although financial wellness is a predictor of physician burnout, we are yet to optimize financial education or wellness of Urology trainees. We assessed existing studies, compared them to those of other specialties, and discussed resources and methods to address this deficiency.</p><p><strong>Recent findings: </strong>Urology residents tend to be less fiscally savvy (carry significant debt, and lack retirement savings or disability insurance), and 90% of trainees and young Urologists do not feel comfortable with the business of practice, including skills like coding and billing, contract negotiation, and self-value assessment. Financial and business literacy are deficiencies of Urology training, as in other specialties. Eventually, the goal should be universal adoption of a formal curriculum that is graded in nature. In the interim, we need to propose and endorse adoption of a formal curriculum, and we should support trainees by promoting a space for easily accessible and transparent information regarding best practices in personal finance and the business of healthcare.</p>","PeriodicalId":11112,"journal":{"name":"Current Urology Reports","volume":" ","pages":"207-214"},"PeriodicalIF":2.5,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141431640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Advancements in Surgical Management of Megaureters. 巨尿道手术治疗的进展。
IF 2.5 2区 医学
Current Urology Reports Pub Date : 2024-09-01 Epub Date: 2024-07-02 DOI: 10.1007/s11934-024-01214-8
Timothy C Boswell
{"title":"Advancements in Surgical Management of Megaureters.","authors":"Timothy C Boswell","doi":"10.1007/s11934-024-01214-8","DOIUrl":"10.1007/s11934-024-01214-8","url":null,"abstract":"<p><strong>Purpose of review: </strong>To review and describe the recent evolution of surgery for the various types of pediatric megaureter.</p><p><strong>Recent findings: </strong>Megaureter management first relies on determining the underlying cause, whether by obstruction, reflux, or a combination, and then setting appropriate surgical indications because many cases do not require surgery as shown by observation studies. Endoscopic balloon dilation has been on the rise as a major treatment option for obstructive megaureter, while refluxing megaureters can also be treated by laparoscopic and robotic techniques, whether extravesically or transvesicoscopically. During ureteral reimplantation, tapering is sometimes necessary to address the enlarged ureter, but there are also considerations for not tapering or for tapering alternatives. Endoscopic and minimally invasive surgeries for megaureter have been the predominant focus of recent megaureter literature. These techniques still need collaborative prospective studies to better define which surgeries are best for patients needing megaureter interventions.</p>","PeriodicalId":11112,"journal":{"name":"Current Urology Reports","volume":" ","pages":"215-223"},"PeriodicalIF":2.5,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11306539/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141491249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Role of Genetic Testing in Kidney Stone Disease: A Narrative Review 基因检测在肾结石病中的作用:叙述性综述
IF 2.6 2区 医学
Current Urology Reports Pub Date : 2024-08-03 DOI: 10.1007/s11934-024-01225-5
Robert Geraghty, Catherine Lovegrove, Sarah Howles, John A. Sayer
{"title":"Role of Genetic Testing in Kidney Stone Disease: A Narrative Review","authors":"Robert Geraghty, Catherine Lovegrove, Sarah Howles, John A. Sayer","doi":"10.1007/s11934-024-01225-5","DOIUrl":"https://doi.org/10.1007/s11934-024-01225-5","url":null,"abstract":"<h3 data-test=\"abstract-sub-heading\">Purpose of Review</h3><p>Kidney stone disease (KSD) is a common and potentially life-threatening condition, and half of patients experience a repeat kidney stone episode within 5–10 years. Despite the ~50% estimate heritability of KSD, international guidelines have not kept up with the pace of discovery of genetic causes of KSD. The European Association of Urology guidelines lists 7 genetic causes of KSD as ‘high risk’.</p><h3 data-test=\"abstract-sub-heading\">Recent Findings</h3><p>There are currently 46 known monogenic (single gene) causes of kidney stone disease, with evidence of association in a further 23 genes. There is also evidence for polygenic risk of developing KSD. Evidence is lacking for recurrent disease, and only one genome wide association study has investigated this phenomenon, identifying two associated genes (<i>SLC34A1</i> and <i>TRPV5</i>). However, in the absence of other evidence, patients with genetic predisposition to KSD should be treated as ‘high risk’. Further studies are needed to characterize both monogenic and polygenic associations with recurrent disease, to allow for appropriate risk stratification. Durability of test result must be balanced against cost. This would enable retrospective analysis if no genetic cause was found initially.</p><h3 data-test=\"abstract-sub-heading\">Summary</h3><p>We recommend genetic testing using a gene panel for all children, adults &lt; 25 years, and older patients who have factors associated with high risk disease within the context of a wider metabolic evaluation. Those with a genetic predisposition should be managed via a multi-disciplinary team approach including urologists, radiologists, nephrologists, clinical geneticists and chemical pathologists. This will enable appropriate follow-up, counselling and potentially prophylaxis.</p>","PeriodicalId":11112,"journal":{"name":"Current Urology Reports","volume":"15 1","pages":""},"PeriodicalIF":2.6,"publicationDate":"2024-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141881735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Plastic Clamp Versus Conventional Surgical Dissection Technique in Pediatric Circumcision: A Systematic Review and Meta-Analysis. 小儿包皮环切术中的塑料夹钳与传统手术剥离技术:系统综述与元分析》。
IF 2.5 2区 医学
Current Urology Reports Pub Date : 2024-08-01 Epub Date: 2024-05-21 DOI: 10.1007/s11934-024-01209-5
Xianming Yao, Gang Zhang, Qianwei Xiong, Shaoguang Feng, Xian Liu
{"title":"Plastic Clamp Versus Conventional Surgical Dissection Technique in Pediatric Circumcision: A Systematic Review and Meta-Analysis.","authors":"Xianming Yao, Gang Zhang, Qianwei Xiong, Shaoguang Feng, Xian Liu","doi":"10.1007/s11934-024-01209-5","DOIUrl":"10.1007/s11934-024-01209-5","url":null,"abstract":"<p><strong>Purpose: </strong>Phimosis is a common condition of the urinary system in children and often requires surgical treatment. However, the optimal method of circumcision for children has not been determined. We conducted a systematic review and meta-analysis to compare the safety and effectiveness of plastic clamp with conventional surgical circumcision in pediatric circumcision.</p><p><strong>Methods: </strong>A literature search was carried out to compare the plastic clamp and conventional dissection technique in the pediatric population. The following search terms were used: \"circumcision\", \"plastic clamp\", \"conventional\", \"plastibell\", \"children\" and etc. Meta-analysis was used to pool and evaluate variables such as operative time, blood loss, wound infection, bleeding, edema, and total postoperative complications.</p><p><strong>Results: </strong>The plastic clamp technique (PCT) was used in 10,412 of the 17,325 participants in the nine studies, while the conventional surgical dissection technique (CST) was used on 6913 patients. When compared to the CST approach, the PCT approach resulted in shorter operative times (mean difference (MD) -17.48, 95% CI -22 to -12.96; P < 0.001), less blood loss (MD -4.25, 95% CI -7.75 to -0.77; P = 0.02), and a higher incidence of postoperative edema (OR 2.33, 95% CI 1.34 to 4.08; P = 0.003). However, no significant difference was found in the incidence of postoperative complications, including wound infection and bleeding between PCT and CST.</p><p><strong>Conclusions: </strong>PCT is a safe and time-saving option in the pediatric population. However, this method appeared to have a significant greater rate of postoperative edema.</p>","PeriodicalId":11112,"journal":{"name":"Current Urology Reports","volume":" ","pages":"173-180"},"PeriodicalIF":2.5,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141070226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Overview of Radiation Therapy in the Management of Localized and Metastatic Prostate Cancer. 放射治疗治疗局部和转移性前列腺癌概述。
IF 2.5 2区 医学
Current Urology Reports Pub Date : 2024-08-01 Epub Date: 2024-06-11 DOI: 10.1007/s11934-024-01217-5
Malcolm D Mattes
{"title":"Overview of Radiation Therapy in the Management of Localized and Metastatic Prostate Cancer.","authors":"Malcolm D Mattes","doi":"10.1007/s11934-024-01217-5","DOIUrl":"10.1007/s11934-024-01217-5","url":null,"abstract":"<p><strong>Purpose of review: </strong>The goal is to describe the evolution of radiation therapy (RT) utilization in the management of localized and metastatic prostate cancer.</p><p><strong>Recent findings: </strong>Long term data for a variety of hypofractionated definitive RT dose-fractionation schemes has matured, allowing patients and providers many standard-of-care options to choose from. Post-prostatectomy, adjuvant RT has largely been replaced by an early salvage approach. Multiparametric MRI and PSMA PET have enabled increasingly targeted RT delivery to the prostate and oligometastatic tumors. Areas of active investigation include determining the value of proton beam therapy and perirectal spacers, and optimally incorporate genomic tumor profiling and next generation hormonal therapies with RT in the curative setting. The use of radiation therapy to treat prostate cancer is rapidly evolving. In the coming years, there will be continued improvements in a variety of areas to enhance the value of RT in multidisciplinary prostate cancer management.</p>","PeriodicalId":11112,"journal":{"name":"Current Urology Reports","volume":" ","pages":"181-192"},"PeriodicalIF":2.5,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141300309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Digital Rectal Exam in Prostate Cancer Screening and Elevated PSA Work-up-Is there a role anymore? 前列腺癌筛查和 PSA 升高检查中的数字直肠检查--还有作用吗?
IF 2.5 2区 医学
Current Urology Reports Pub Date : 2024-08-01 Epub Date: 2024-06-13 DOI: 10.1007/s11934-024-01218-4
Lane Shish, Joseph Zabell
{"title":"Digital Rectal Exam in Prostate Cancer Screening and Elevated PSA Work-up-Is there a role anymore?","authors":"Lane Shish, Joseph Zabell","doi":"10.1007/s11934-024-01218-4","DOIUrl":"10.1007/s11934-024-01218-4","url":null,"abstract":"<p><strong>Purpose of review: </strong>Prostate cancer (PCa) screening tools, particularly digital rectal examination (DRE), are under scrutiny. This review assesses the utility of DRE in PCa screening.</p><p><strong>Recent findings: </strong>Recent studies reaffirm the DRE's sensitivity and specificity, a higher PCa detection rate with PSA in conjunction with DRE, and a slightly elevated risk of clinically significant PCa (CSPC) in those with elevated PSA and suspicious DRE. Studies confirm high accuracy of MRI in identifying CSPC, with ongoing research exploring its screening potential. DRE alone lacks accuracy for PCa screening, often resulting in missed diagnoses and unnecessary biopsies. Its supplementary use with PSA marginally increases detection rates of identifying a small percentage of CSPC, but the benefit remains questionable. Emerging evidence suggests MRI has the potential as a superior screening tool compared to DRE, although direct comparative studies are lacking. Overall, the DRE has a limited role in current PCa screening.</p>","PeriodicalId":11112,"journal":{"name":"Current Urology Reports","volume":" ","pages":"193-199"},"PeriodicalIF":2.5,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141310316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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