Dermatologica Sinica最新文献_第10页

Apremilast for lithium-associated psoriasis 阿普拉米司特治疗锂相关银屑病

IF 2.5 4区医学

Dermatologica Sinica Pub Date : 2022-07-01 DOI: 10.4103/ds.ds_32_22

J. Youh, H. Miyazawa, H. Iwata, K. Natsuga, H. Ujiie

引用次数: 2

Folliculotropic mycosis fungoides successfully treated with bath psoralen plus ultraviolet a therapy 沐浴补骨脂素加紫外线疗法治疗嗜滤泡性真菌病成功

IF 2.5 4区医学

Dermatologica Sinica Pub Date : 2022-07-01 DOI: 10.4103/1027-8117.354328

Yu-Ting Hung, Meng-Sui Lee, Tai‐Chung Huang, S. Wen, R. Lin, Islamova LIu

引用次数: 0

A novel mutation in Keratin 10 passed down in a family with familial steatocystoma multiplex 角蛋白10的新突变在家族性多发性脂肪囊瘤家族中遗传

IF 2.5 4区医学

Dermatologica Sinica Pub Date : 2022-07-01 DOI: 10.4103/1027-8117.357356

Kun-Lin Lu, Chuang-Wei Wang, W. Chung, Fang-Ying Wang

引用次数: 1

A case of papuloerythroderma of Ofuji possibly associated with a combination drug of losartan potassium/hydrochlorothiazide 大富士丘疹性红皮病1例，可能与氯沙坦钾/氢氯噻嗪联合用药有关

IF 2.5 4区医学

Dermatologica Sinica Pub Date : 2022-07-01 DOI: 10.4103/ds.ds_30_22

G. Egawa, K. Kabashima

引用次数: 2

Skin microbiome in acne vulgaris, skin aging, and rosacea: An evidence-based review 寻常痤疮、皮肤老化和酒渣鼻的皮肤微生物组:一项基于证据的综述

IF 2.5 4区医学

Dermatologica Sinica Pub Date : 2022-07-01 DOI: 10.4103/ds.ds_28_22

Yu-Ching Weng, Yi-Ju Chen

{"title":"Skin microbiome in acne vulgaris, skin aging, and rosacea: An evidence-based review","authors":"Yu-Ching Weng, Yi-Ju Chen","doi":"10.4103/ds.ds_28_22","DOIUrl":"https://doi.org/10.4103/ds.ds_28_22","url":null,"abstract":"The goal of this systematic review was to explore emerging perspectives on the role of skin microbiota in acne vulgaris, skin aging, and rosacea. We searched the literature for published clinical trials, randomized controlled trials, cross-sectional studies, and cohort studies, both experimental and observational, whose primary main purpose was to ascertain the associations between the skin microbiome and chronic skin disease, acne vulgaris, rosacea, and skin aging, using the Embase and PubMed databases. Fifty-one relevant published articles were identified for systematic review (up to December 2021). The possible roles of the skin microbiome in these skin diseases were explored to shed light on its development and to identify potential therapeutic targets for treatment. However, the mechanisms of microbial interaction in these diseases are still under-studied. The results of this evidence-based review suggest that it may be possible to develop individualized therapies targeting the pathogenic strains within the skin microbiome involved in these diseases. This alternative therapeutic approach, involving modifications of the microbiome, may form the basis of the next generation of treatment, known collectively as “ecobiological” anti-inflammatory therapies.","PeriodicalId":11107,"journal":{"name":"Dermatologica Sinica","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91380874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Prevalence and associated factors of skin diseases among geriatric outpatients from a metropolitan dermatologic clinic in Thailand 泰国一个大都市皮肤病诊所老年门诊患者的皮肤病患病率及相关因素

IF 2.5 4区医学

Dermatologica Sinica Pub Date : 2022-07-01 DOI: 10.4103/1027-8117.354329

Jedpakorn Laopakorn, Sujirod Hanthavichai

{"title":"Prevalence and associated factors of skin diseases among geriatric outpatients from a metropolitan dermatologic clinic in Thailand","authors":"Jedpakorn Laopakorn, Sujirod Hanthavichai","doi":"10.4103/1027-8117.354329","DOIUrl":"https://doi.org/10.4103/1027-8117.354329","url":null,"abstract":"Background: The importance of the geriatric population has been increasing expeditiously in the health-care system. The epidemiology of skin disorders is an interesting subject to challenge physicians to comprehensively manage the elderly. Objectives: The objective of the study was to determine the prevalence of the most frequent dermatologic disorders among elderly outpatients and identify major associated determinants. Methods: This retrospective observational study recruited subjects aged 60 years and older attending the dermatologic clinic at the Faculty of Medicine, Vajira Hospital, in Thailand. The medical records were collected between January 2017 and December 2020. The data were analyzed according to age, sex, season, underlying medical diseases, and areas of involvement to identify the associated factors for the frequently presented dermatologic diagnoses. Results: In this study, 521 outpatients (including 218 males and 303 females) with a mean age of 71.34 years (range, 60–04 years) were enrolled. The most common dermatoses were eczematous dermatitis (35.7%), cutaneous infection (18.2%), xerosis (15.5%), and psoriasis (7.3%). The distribution of the prevalent dermatologic disorders still did not change during the COVID-19 pandemic. A significant association was found between xerosis and age of 80 years and older (odds ratio [OR], 2.03; 95% confidence interval [CI], 1.09–3.78; P = 0.026). The risk of developing xerosis cutis significantly decreased with dyslipidemia (OR, 0.45; 95% CI, 0.26–0.78; P = 0.004). Conclusion: The three foremost cutaneous disease groups are eczematous dermatitis, skin infection, and xerosis cutis. Dry skin is strongly connected with the age of 80 years and above; however, xerosis is coincidentally correlated with dyslipidemia.","PeriodicalId":11107,"journal":{"name":"Dermatologica Sinica","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72409503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Cutaneous annular erythema associated with Sjögren's syndrome successfully treated by baricitinib baricitinib成功治疗Sjögren综合征相关皮肤环状红斑

IF 2.5 4区医学

Dermatologica Sinica Pub Date : 2022-07-01 DOI: 10.4103/1027-8117.355702

Sheng-Wen Liu, Wei-Ming Wang, Chien-Ping Chiang, Chih-Tsung Hung, Yi-Hsien Chen

引用次数: 0

Coronavirus disease 2019 in dermatology practice: Perspective of three levels of prevention on public health 2019冠状病毒病在皮肤科实践中的应用:三个层面的公共卫生预防视角

IF 2.5 4区医学

Dermatologica Sinica Pub Date : 2022-07-01 DOI: 10.4103/ds.ds_33_22

Chengwen Luo, C. Geng, Yung-Hsien Tung, Bing-Long Wang, T. Tung

{"title":"Coronavirus disease 2019 in dermatology practice: Perspective of three levels of prevention on public health","authors":"Chengwen Luo, C. Geng, Yung-Hsien Tung, Bing-Long Wang, T. Tung","doi":"10.4103/ds.ds_33_22","DOIUrl":"https://doi.org/10.4103/ds.ds_33_22","url":null,"abstract":"Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2, has become a major public exigency of international concern. The COVID-19 epidemic has spread rapidly around the world, profoundly impacting people's lives. Patients are among those most affected by the pandemic. COVID-19 has adversely affected health-care systems, and the effects are long-lasting and devastating. Most medical institutions in the impacted countries and regions have been imbued with COVID-19 cases, both confirmed and suspected, leading to an overburdened health-care workforce like never before. While most of the critical situations involved internal medicine departments, such as infectious diseases, and intensive care units, other specialties, including dermatology, have also been profoundly affected by this pandemic. Dermatoepidemiology, the application of epidemiological methods to dermatology practice, is an important emerging discipline in dermatology. In this review, we discussed the influence of the COVID-19 epidemic on dermatology practice, as well as the application of public health strategies in dermatology. These findings from genetic epidemiological research, clinical trial networks, and pharmacovigilance research suggested that further research in dermatology requires collaborative studies across different fields, institutions, and countries. To solve the highly complex unsolved problems that we face, dermatologists and epidemiologists should be dynamic team members with multiple approach skills.","PeriodicalId":11107,"journal":{"name":"Dermatologica Sinica","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86002560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Three monthly doses of corticosteroid pulse therapy yields a satisfactory but temporary response in severe alopecia areata patients 三个月剂量的皮质类固醇脉冲治疗产生满意的，但暂时的反应严重斑秃患者

IF 2.5 4区医学

Dermatologica Sinica Pub Date : 2022-07-01 DOI: 10.4103/1027-8117.357355

Heng-An Lu, Chao-Chun Yang, Yu-Chen Chen

{"title":"Three monthly doses of corticosteroid pulse therapy yields a satisfactory but temporary response in severe alopecia areata patients","authors":"Heng-An Lu, Chao-Chun Yang, Yu-Chen Chen","doi":"10.4103/1027-8117.357355","DOIUrl":"https://doi.org/10.4103/1027-8117.357355","url":null,"abstract":"Alopecia areata (AA) is a common, nonscarring type of alopecia that can cause chronic and severe hair loss in some cases. Although there is no standard established protocol for the use of corticosteroid pulse therapy, it has been reported to be an effective and well-tolerated treatment option for patients with severe AA. This study retrospectively analyzed 29 patients who were diagnosed with severe AA (>50% hair loss) from January 2010 to December 2020 and treated with 3 monthly sessions of intravenous corticosteroids. Methylprednisolone (500 mg/day) was administered for 3 consecutive days during the first session, followed by a 1-day treatment regimen for the second and third sessions. The treatment had an overall satisfactory response rate of 58.6% and a complete response rate of 13.8%. Eleven of the 13 patients who achieved a satisfactory response experienced relapse. A subgroup analysis showed that patients with a shorter duration of AA (≤6 months) had a significantly better response to corticosteroid pulse therapy. This study highlights that 3 monthly sessions of corticosteroid therapy are sufficient to induce satisfactory but temporary response.","PeriodicalId":11107,"journal":{"name":"Dermatologica Sinica","volume":null,"pages":null},"PeriodicalIF":2.5,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74318671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Next-generation bioinformatics in dermatology research 皮肤病学研究中的下一代生物信息学

IF 2.5 4区医学

Dermatologica Sinica Pub Date : 2022-07-01 DOI: 10.4103/1027-8117.357359

Yi-Ju Chen

引用次数: 0