Dermatologica Sinica最新文献_第10页

Prevalence and associated factors of skin diseases among geriatric outpatients from a metropolitan dermatologic clinic in Thailand 泰国一个大都市皮肤病诊所老年门诊患者的皮肤病患病率及相关因素

IF 2.5 4区医学

Dermatologica Sinica Pub Date : 2022-07-01 DOI: 10.4103/1027-8117.354329

Jedpakorn Laopakorn, Sujirod Hanthavichai

{"title":"Prevalence and associated factors of skin diseases among geriatric outpatients from a metropolitan dermatologic clinic in Thailand","authors":"Jedpakorn Laopakorn, Sujirod Hanthavichai","doi":"10.4103/1027-8117.354329","DOIUrl":"https://doi.org/10.4103/1027-8117.354329","url":null,"abstract":"Background: The importance of the geriatric population has been increasing expeditiously in the health-care system. The epidemiology of skin disorders is an interesting subject to challenge physicians to comprehensively manage the elderly. Objectives: The objective of the study was to determine the prevalence of the most frequent dermatologic disorders among elderly outpatients and identify major associated determinants. Methods: This retrospective observational study recruited subjects aged 60 years and older attending the dermatologic clinic at the Faculty of Medicine, Vajira Hospital, in Thailand. The medical records were collected between January 2017 and December 2020. The data were analyzed according to age, sex, season, underlying medical diseases, and areas of involvement to identify the associated factors for the frequently presented dermatologic diagnoses. Results: In this study, 521 outpatients (including 218 males and 303 females) with a mean age of 71.34 years (range, 60–04 years) were enrolled. The most common dermatoses were eczematous dermatitis (35.7%), cutaneous infection (18.2%), xerosis (15.5%), and psoriasis (7.3%). The distribution of the prevalent dermatologic disorders still did not change during the COVID-19 pandemic. A significant association was found between xerosis and age of 80 years and older (odds ratio [OR], 2.03; 95% confidence interval [CI], 1.09–3.78; P = 0.026). The risk of developing xerosis cutis significantly decreased with dyslipidemia (OR, 0.45; 95% CI, 0.26–0.78; P = 0.004). Conclusion: The three foremost cutaneous disease groups are eczematous dermatitis, skin infection, and xerosis cutis. Dry skin is strongly connected with the age of 80 years and above; however, xerosis is coincidentally correlated with dyslipidemia.","PeriodicalId":11107,"journal":{"name":"Dermatologica Sinica","volume":"44 10","pages":"168 - 173"},"PeriodicalIF":2.5,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72409503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Coronavirus disease 2019 in dermatology practice: Perspective of three levels of prevention on public health 2019冠状病毒病在皮肤科实践中的应用:三个层面的公共卫生预防视角

IF 2.5 4区医学

Dermatologica Sinica Pub Date : 2022-07-01 DOI: 10.4103/ds.ds_33_22

Chengwen Luo, C. Geng, Yung-Hsien Tung, Bing-Long Wang, T. Tung

{"title":"Coronavirus disease 2019 in dermatology practice: Perspective of three levels of prevention on public health","authors":"Chengwen Luo, C. Geng, Yung-Hsien Tung, Bing-Long Wang, T. Tung","doi":"10.4103/ds.ds_33_22","DOIUrl":"https://doi.org/10.4103/ds.ds_33_22","url":null,"abstract":"Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2, has become a major public exigency of international concern. The COVID-19 epidemic has spread rapidly around the world, profoundly impacting people's lives. Patients are among those most affected by the pandemic. COVID-19 has adversely affected health-care systems, and the effects are long-lasting and devastating. Most medical institutions in the impacted countries and regions have been imbued with COVID-19 cases, both confirmed and suspected, leading to an overburdened health-care workforce like never before. While most of the critical situations involved internal medicine departments, such as infectious diseases, and intensive care units, other specialties, including dermatology, have also been profoundly affected by this pandemic. Dermatoepidemiology, the application of epidemiological methods to dermatology practice, is an important emerging discipline in dermatology. In this review, we discussed the influence of the COVID-19 epidemic on dermatology practice, as well as the application of public health strategies in dermatology. These findings from genetic epidemiological research, clinical trial networks, and pharmacovigilance research suggested that further research in dermatology requires collaborative studies across different fields, institutions, and countries. To solve the highly complex unsolved problems that we face, dermatologists and epidemiologists should be dynamic team members with multiple approach skills.","PeriodicalId":11107,"journal":{"name":"Dermatologica Sinica","volume":"15 1","pages":"143 - 147"},"PeriodicalIF":2.5,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86002560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Next-generation bioinformatics in dermatology research 皮肤病学研究中的下一代生物信息学

IF 2.5 4区医学

Dermatologica Sinica Pub Date : 2022-07-01 DOI: 10.4103/1027-8117.357359

Yi-Ju Chen

引用次数: 0

Three monthly doses of corticosteroid pulse therapy yields a satisfactory but temporary response in severe alopecia areata patients 三个月剂量的皮质类固醇脉冲治疗产生满意的，但暂时的反应严重斑秃患者

IF 2.5 4区医学

Dermatologica Sinica Pub Date : 2022-07-01 DOI: 10.4103/1027-8117.357355

Heng-An Lu, Chao-Chun Yang, Yu-Chen Chen

{"title":"Three monthly doses of corticosteroid pulse therapy yields a satisfactory but temporary response in severe alopecia areata patients","authors":"Heng-An Lu, Chao-Chun Yang, Yu-Chen Chen","doi":"10.4103/1027-8117.357355","DOIUrl":"https://doi.org/10.4103/1027-8117.357355","url":null,"abstract":"Alopecia areata (AA) is a common, nonscarring type of alopecia that can cause chronic and severe hair loss in some cases. Although there is no standard established protocol for the use of corticosteroid pulse therapy, it has been reported to be an effective and well-tolerated treatment option for patients with severe AA. This study retrospectively analyzed 29 patients who were diagnosed with severe AA (>50% hair loss) from January 2010 to December 2020 and treated with 3 monthly sessions of intravenous corticosteroids. Methylprednisolone (500 mg/day) was administered for 3 consecutive days during the first session, followed by a 1-day treatment regimen for the second and third sessions. The treatment had an overall satisfactory response rate of 58.6% and a complete response rate of 13.8%. Eleven of the 13 patients who achieved a satisfactory response experienced relapse. A subgroup analysis showed that patients with a shorter duration of AA (≤6 months) had a significantly better response to corticosteroid pulse therapy. This study highlights that 3 monthly sessions of corticosteroid therapy are sufficient to induce satisfactory but temporary response.","PeriodicalId":11107,"journal":{"name":"Dermatologica Sinica","volume":"154 1","pages":"178 - 181"},"PeriodicalIF":2.5,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74318671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Papuloerythroderma of Ofuji as a paraneoplastic phenomenon in a patient with lung cancer 大富士丘疹红皮病作为肺癌患者的副肿瘤现象

IF 2.5 4区医学

Dermatologica Sinica Pub Date : 2022-07-01 DOI: 10.4103/ds.ds_25_22

Wei-Yao Wang, Yue-Chiu Su, Cheng-Che Lan, S. Chiu

引用次数: 1

Polypoid basal cell carcinoma: A scoping review 息肉样基底细胞癌:范围回顾

IF 2.5 4区医学

Dermatologica Sinica Pub Date : 2022-07-01 DOI: 10.4103/1027-8117.354330

P. Wu, Ying-Xiu Dai, Yu-Ju Chou, Yung-Ting Chang, Chih-Chiang Chen, Sheng-Hsiang Ma

{"title":"Polypoid basal cell carcinoma: A scoping review","authors":"P. Wu, Ying-Xiu Dai, Yu-Ju Chou, Yung-Ting Chang, Chih-Chiang Chen, Sheng-Hsiang Ma","doi":"10.4103/1027-8117.354330","DOIUrl":"https://doi.org/10.4103/1027-8117.354330","url":null,"abstract":"Polypoid basal cell carcinoma (BCC) is characterized by a stalk connecting the tumor and skin surfaces, with neoplastic cells restricted in the polypoid zone microscopically. A thorough review of polypoid BCC is still lacking. Thus, we performed this scoping review to investigate the clinical manifestations, dermoscopic features, histopathology, treatment, and prognosis of polypoid BCC. A literature search was conducted in the PubMed, Embase, Web of Science, and Cochrane databases until December 23, 2021. Studies reporting at least one patient with polypoid BCC following the pathology and clinical criteria were included. A total of 47 studies with 54 patients with solitary polypoid BCC and 13 patients with multiple polypoid BCCs were included. Solitary polypoid BCC occurred at a relatively younger age, with an equal sex ratio. These tumors most commonly presented as red or flesh-colored pedunculated papules and were commonly distributed over nonsun-exposed areas. Most tumors were managed with excision, and recurrence or metastasis was seldom reported. Most patients with multiple polypoid BCCs had basal cell nevus syndrome and presented with generalized distributed, flesh-colored, or brown papules mimicking skin tags. Typical dermoscopic features of BCC could still be observed in these lesions, including arborizing vessels, blue-gray globules, and ovoid nests, which could aid in early diagnosis. In conclusion, polypoid BCC is a distinct variant of BCC with pedunculated morphology. Physicians should be aware of polypoid BCC and may use dermoscopy to aid in early diagnosis and treatment.","PeriodicalId":11107,"journal":{"name":"Dermatologica Sinica","volume":"46 1","pages":"148 - 155"},"PeriodicalIF":2.5,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90777605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comorbid laboratory abnormalities in female pattern hair loss patients 女性型脱发患者的合并症实验室异常

IF 2.5 4区医学

Dermatologica Sinica Pub Date : 2022-07-01 DOI: 10.4103/1027-8117.357357

Hsin-Jou Wang, Jui-Wen Yeh, Yin-Fan Chang, J. Wu, Chao-Chun Yang

{"title":"Comorbid laboratory abnormalities in female pattern hair loss patients","authors":"Hsin-Jou Wang, Jui-Wen Yeh, Yin-Fan Chang, J. Wu, Chao-Chun Yang","doi":"10.4103/1027-8117.357357","DOIUrl":"https://doi.org/10.4103/1027-8117.357357","url":null,"abstract":"Background: Female pattern hair loss (FPHL) is the main cause of alopecia in women and has a debilitating impact on the quality of life. However, certain comorbid conditions causing hair loss are often masked by FPHL and may remain undetected. Hence, it is imperative to identify them to administer appropriate treatment. The necessity of laboratory tests to evaluate these comorbidities in patients with FPHL has not been established. Objectives: This study aimed to identify the frequency of comorbid abnormalities detected by laboratory tests in patients with FPHL. Methods: Routine laboratory test results of patients with FPHL, who visit our hair clinic for the first time, were retrospectively collected and analyzed. These tests assessed the serum testosterone, thyroid-stimulating hormone, free thyroxin, zinc and ferritin levels, hemoglobin, as well as antinuclear antibody (ANA), and rapid plasma reagin test results. The correlation between age and hair loss severity and the frequency of comorbidities was evaluated using subgroup analysis. Results: Among the 356 patients with FPHL, coexisting zinc deficiency, iron depletion, and thyroid abnormalities were common and present in 41.7%, 39.7%, and 11.3% of them, respectively. The rate of concomitantly increased ANA titers was relatively low (4.4%), while that of syphilis and high serum testosterone levels was extremely low (0.3% and 0%, respectively). Younger patients (<50 years) with FPHL had a higher rate of coexisting iron deficiency than patients in the older age group. Conclusion: Testing for concomitant iron depletion, zinc deficiency, and thyroid disease is recommended in female patients with FPHL.","PeriodicalId":11107,"journal":{"name":"Dermatologica Sinica","volume":"55 1","pages":"174 - 177"},"PeriodicalIF":2.5,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83890221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

YouTube as a source of information for hidradenitis suppurativa treatment YouTube作为化脓性汗腺炎治疗的信息来源

IF 2.5 4区医学

Dermatologica Sinica Pub Date : 2022-07-01 DOI: 10.4103/ds.ds_27_22

Miłosz Lewandowski, Zuzanna Świerczewska, W. Barańska-Rybak

{"title":"YouTube as a source of information for hidradenitis suppurativa treatment","authors":"Miłosz Lewandowski, Zuzanna Świerczewska, W. Barańska-Rybak","doi":"10.4103/ds.ds_27_22","DOIUrl":"https://doi.org/10.4103/ds.ds_27_22","url":null,"abstract":"Background: Hidradenitis suppurativa (HS) is a chronic, inflammatory skin disease characterized by a significant decrease in the patients' quality of life. Patients are increasingly looking for information about HS on social media, including YouTube (YT). However, the quality of the videos in some other diseases has been often scored as poor. Objectives: The aim of this study was to evaluate the usefulness and the quality of the most viewed acne inversa videos on YT. Methods: YT was searched for the keywords “HS” and “acne inversa.” For videos, quality assessment validated DISCERN instrument and the global quality score (GQS) were applied. Furthermore, the popularity of each video using the video power index (VPI) score was evaluated. Results: After applying the exclusion criteria, 34 videos were analyzed. We found that video quality was poor regardless of video type. The mean DISCERN score between the raters was 34.65 ± 10.7, and the mean GQS score was 2.6 ± 0.98. There was no significant correlation between the DISCERN, GQS and VPI, the number of views, likes, dislikes, comments, and video duration. Conclusion: Our study highlights the gaps in knowledge regarding HS treatment on YT. Hence, this information can be used to create superior educational content in the future.","PeriodicalId":11107,"journal":{"name":"Dermatologica Sinica","volume":"40 1","pages":"156 - 161"},"PeriodicalIF":2.5,"publicationDate":"2022-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76201973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hints from the skin beneath: Vitiligo in Vogt–Koyanagi–Harada disease 下面的皮肤提示:Vogt-Koyanagi-Harada病的白癜风

IF 2.5 4区医学

Dermatologica Sinica Pub Date : 2022-04-01 DOI: 10.4103/ds.ds_23_22

Jong Ho Lim, Wooi-Chiang Tan, N. Nor

引用次数: 0

The optimal concentration of intralesional triamcinolone acetonide for patchy alopecia areata: A systematic review and meta-analysis 局部曲安奈德治疗斑状斑秃的最佳浓度:一项系统回顾和荟萃分析

IF 2.5 4区医学

Dermatologica Sinica Pub Date : 2022-04-01 DOI: 10.4103/ds.ds_15_22

Hsuan-An Su, Yu-Tsung Chen, Yu-Chia Chen

{"title":"The optimal concentration of intralesional triamcinolone acetonide for patchy alopecia areata: A systematic review and meta-analysis","authors":"Hsuan-An Su, Yu-Tsung Chen, Yu-Chia Chen","doi":"10.4103/ds.ds_15_22","DOIUrl":"https://doi.org/10.4103/ds.ds_15_22","url":null,"abstract":"Background: Intralesional steroid treatment for alopecia areata (AA) has been developed for decades, yet the optimal concentration of triamcinolone acetonide (TrA) is not well-established. Objectives: This review aims to determine the optimal concentration of intralesional TrA in treating patchy AA. Methods: We conducted a systematic review and meta-analysis, and searched the Cochrane Library, Embase, and PubMed databases on July 4, 2021, to identify randomized or nonrandomized comparative studies reporting the response rates and/or adverse events among AA patients treated with various concentrations of TrA. The meta-analysis of proportions and odds ratios was analyzed using random-effects modeling. Results: Nineteen studies and a total of 783 participants were included. The estimated response rate of 5 mg/dl (74.82%, 95% confidence interval [CI] 64.99%–83.50%) was shown to be more efficacious than 2.5/3.33 mg/dl (38.64%, 95% CI 16.98%–62.99%) but similar to 10 mg/dl (71.06%, 95% CI 59.72%–81.20%), while pooled estimate of odds ratios revealed higher efficacy with 10 mg/dl than 5 mg/dl (odds ratio = 1.64, 95% CI 1.05–2.58, P = 0.031). The rates of skin atrophy were 18.05% (95% CI, 10.32%–27.38%), 11.49% (95% CI, 2.86%–24.84%), and 3.85% (95% CI, 1.27%–14.01%) in groups 10, 5, and 2.5/3.33 mg/dl, respectively. Higher concentration is associated with more skin atrophy in a dose-dependent fashion (P = 0.012). Heterogeneity among studies in the meta-analyses was high. Conclusion: The optimal intralesional concentration of TrA for patchy AA is probably 10 mg/dl with acceptable adverse events.","PeriodicalId":11107,"journal":{"name":"Dermatologica Sinica","volume":"198 1","pages":"85 - 93"},"PeriodicalIF":2.5,"publicationDate":"2022-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89010984","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1