Charles Teames, Scott R Florell, Christopher Hansen
{"title":"A novel presentation of calcinosis cutis of the scalp in adult dermatomyositis.","authors":"Charles Teames, Scott R Florell, Christopher Hansen","doi":"10.5070/D331164984","DOIUrl":"https://doi.org/10.5070/D331164984","url":null,"abstract":"<p><p>Dystrophic calcinosis cutis is the aberrant deposition of insoluble calcium in cutaneous tissue generally secondary to inflammatory connective tissue disease. Although calcinosis cutis is commonly seen in juvenile dermatomyositis, it is a relatively rare occurrence in adult disease. Herein, we discuss an 82-year-old woman with extensive history of dermatomyositis of the scalp who presented with new-onset calcinosis cutis of the scalp.</p>","PeriodicalId":11040,"journal":{"name":"Dermatology online journal","volume":"31 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144316099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yen Luu, Brooks D Kimmis, Anika Pulumati, Sandra Jaroonwanichkul, Garth Fraga, Anand Rajpara
{"title":"Squamous cell carcinoma originating in folliculitis decalvans.","authors":"Yen Luu, Brooks D Kimmis, Anika Pulumati, Sandra Jaroonwanichkul, Garth Fraga, Anand Rajpara","doi":"10.5070/D331164986","DOIUrl":"https://doi.org/10.5070/D331164986","url":null,"abstract":"<p><p>Folliculitis decalvans is a chronic and progressive scarring alopecia at the vertex and occipital scalp with a predilection for middle-aged men. Squamous cell carcinoma is an exceedingly rare complication of folliculitis decalvans, reported in 5 cases to date. Herein, we present a case of squamous cell carcinoma of the scalp in a patient diagnosed with recalcitrant folliculitis decalvans and review the clinicopathologic characteristics of all reported cases in the literature.</p>","PeriodicalId":11040,"journal":{"name":"Dermatology online journal","volume":"31 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144316151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Joshua Burshtein, Raj Chovatiya, Alexandra Golant, Danny Zakria, Milaan Shah, Peter Lio, Mark Lebwohl
{"title":"Risks of topical corticosteroid therapy and role for advanced targeted topical treatments for inflammatory skin diseases: an expert consensus panel.","authors":"Joshua Burshtein, Raj Chovatiya, Alexandra Golant, Danny Zakria, Milaan Shah, Peter Lio, Mark Lebwohl","doi":"10.5070/D331164978","DOIUrl":"https://doi.org/10.5070/D331164978","url":null,"abstract":"<p><p>Topical corticosteroids are a first-line therapy for inflammatory skin diseases and are commonly used for chronic management. Topical corticosteroids can lead to cutaneous and systemic adverse events. The purpose of this expert consensus panel was to review published literature on the safety and efficacy of topical corticosteroids and role for advanced targeted topical therapies for inflammatory skin diseases. A comprehensive literature search was completed using a combination of keywords: \"topical,\" \"corticosteroid,\" \"non-steroid,\" \"efficacy,\" \"adverse effects,\" \"malpractice,\" and \"inflammatory skin diseases.\" Articles were screened for relevance to topic of safety and efficacy of topical corticosteroids and noncorticosteroid therapies for inflammatory skin diseases. A panel of four dermatologists with expertise treating inflammatory skin diseases reviewed the articles and created consensus statements. A modified Delphi process was used to approve each statement and a strength of recommendation was assigned. The literature search produced 350 articles. A screening of the studies resulted in 24 articles that met criteria. The panel unanimously voted to adopt 10 consensus statements and recommendations. Topical corticosteroids and systemic corticosteroids are associated with numerous adverse effects, and medical-legal risks for clinicians prescribing these medications exist. Advanced targeted topical therapies have demonstrated safety and effectiveness as an alternative to corticosteroids.</p>","PeriodicalId":11040,"journal":{"name":"Dermatology online journal","volume":"31 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144316149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tara Suresh, Bruin Pollard, Hana Hajda, Lily Chen, Ilana Rosman
{"title":"Urgent care in dermatology: first year experience of an academic clinic.","authors":"Tara Suresh, Bruin Pollard, Hana Hajda, Lily Chen, Ilana Rosman","doi":"10.5070/D331164972","DOIUrl":"https://doi.org/10.5070/D331164972","url":null,"abstract":"","PeriodicalId":11040,"journal":{"name":"Dermatology online journal","volume":"31 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144316152","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Oluwaseyi O Adeuyan, Celine M Schreidah, Lauren M Fahmy, Emily R Gordon, Brigit A Lapolla, Larisa J Geskin
{"title":"A case of mixed mycosis fungoides and superficial morphea: a clinicohistopathologic challenge.","authors":"Oluwaseyi O Adeuyan, Celine M Schreidah, Lauren M Fahmy, Emily R Gordon, Brigit A Lapolla, Larisa J Geskin","doi":"10.5070/D331164985","DOIUrl":"https://doi.org/10.5070/D331164985","url":null,"abstract":"","PeriodicalId":11040,"journal":{"name":"Dermatology online journal","volume":"31 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144316098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mckenzie DiLeo, Reece Moore, Emelie E Nelson, Rashid M Rashid
{"title":"A unique presentation of diffuse multiple eruptive milia.","authors":"Mckenzie DiLeo, Reece Moore, Emelie E Nelson, Rashid M Rashid","doi":"10.5070/D331164967","DOIUrl":"10.5070/D331164967","url":null,"abstract":"<p><p>Milia are small, benign firm white papules that commonly manifest on the face and torso. Several subtypes exist, including multiple eruptive milia-a condition characterized by the eruption of numerous milia that arise over the course of weeks to months. Although limited literature exists on this rare presentation, there seems to be no uniform patient demographic, etiology, or consistent anatomical localization of the milia. We describe a case of multiple eruptive milia presenting diffusely across the cheeks, forehead, superior neck, and preauricular and postauricular skin of an adult female. Additionally, this case is particularly unique as biopsies of representative lesions demonstrate a distinct lymphohistiocytic infiltrate. This atypical presentation underscores a gap in literature regarding multiple eruptive milia and calls into question whether a subtype of milia may exist with an inflammatory component.</p>","PeriodicalId":11040,"journal":{"name":"Dermatology online journal","volume":"31 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144316100","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chinenye Onejeme, Mary Fitzgibbon, Antonio Jimenez, Lindy Ross
{"title":"Clinical pearls addressing hair growth and loss in transgender patients on hormone replacement therapy.","authors":"Chinenye Onejeme, Mary Fitzgibbon, Antonio Jimenez, Lindy Ross","doi":"10.5070/D331164961","DOIUrl":"https://doi.org/10.5070/D331164961","url":null,"abstract":"<p><p>Hair is a defining feature of human appearance and plays an essential role in personality and identity development. Currently, about 1.6% of US adults identify as transgender. Within the transgender community, hair serves not only as a means of self-expression but also as a crucial element in affirming gender identity, helping individuals to align their outward appearance with their inner sense of self. However, there are significant disparities in the care provided to transgender patients, particularly those seeking a more masculine or feminine appearance through hormone replacement therapy. Studies on transgender patient satisfaction with current therapies are limited but indicate overall dissatisfaction with the standard of care. Dermatologists play a pivotal role in advocating and caring for transgender patients regarding their hair and skin needs. A deeper understanding of hormone replacement therapy and hair growth/loss therapy is crucial to prescribing medications aligned with patients' treatment goals. This commentary aims to provide clinical guidance to dermatologists, aiding them in educating transgender patients undergoing hormone replacement therapy about accessible options for hair growth and loss. Treatment algorithms have been proposed based on efficacy, pharmacodynamic interactions with hormone replacement therapy, cost-effectiveness, adverse reactions, and care accessibility tailored specifically for transfeminine and transmasculine patients.</p>","PeriodicalId":11040,"journal":{"name":"Dermatology online journal","volume":"31 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144316139","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Fatma Said, Maysam Jridi, Ines Naceur, Tayssir Ben Achour, Monia Smiti
{"title":"Rituximab treatment of refractory skin involvement in anti-TIF1 gamma dermatomyositis.","authors":"Fatma Said, Maysam Jridi, Ines Naceur, Tayssir Ben Achour, Monia Smiti","doi":"10.5070/D331164969","DOIUrl":"https://doi.org/10.5070/D331164969","url":null,"abstract":"<p><p>Dermatomyositis is one type among a heterogeneous group of idiopathic inflammatory myopathies. Among these anti-TIF1 gamma dermatomyositis is characterized by specific skin lesions, often severe and refractory to conventional treatments. We report a 58-year-old woman who had fatigue associated with myalgia with proximal and bilateral muscle weakness along with a generalized lilac erythematous rash on the face with Gottron papules on the metacarpophalangeal joints and periungual erythema on both hands. She also exhibited a widespread dark-violaceous-red skin eruption on the whole trunk. She was diagnosed with anti-TIF1 gamma dermatomyositis and received a treatment regimen of topical corticosteroids, hydroxychloroquine, oral corticosteroids, and conventional immunosuppressive drugs (methotrexate, azathioprine, mycophenolate mofetil, cyclophosphamide, and immunoglobulins) with no improvement of the skin rash. Therefore, she received rituximab, and three months later, the skin lesions improved magnificently. Rituximab is an efficient and safe option for patients with dermatomyositis-related skin disease refractory to conventional treatments.</p>","PeriodicalId":11040,"journal":{"name":"Dermatology online journal","volume":"31 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144316150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jesus Enrique Duenaz-Diaz, Dinorah Elizabeth Paz-Luna, Isaias Giovanni Duenaz-Diaz, Astrid Salcedo-Gomez, Gema Yasmin Aguilar-Roman, Vanesa Paredes-Solis, Sara Elena Chavez-Guzman, Elsa Daniela Zavala-Alvarez
{"title":"Early malignant syphilis in an immunocompetent young man.","authors":"Jesus Enrique Duenaz-Diaz, Dinorah Elizabeth Paz-Luna, Isaias Giovanni Duenaz-Diaz, Astrid Salcedo-Gomez, Gema Yasmin Aguilar-Roman, Vanesa Paredes-Solis, Sara Elena Chavez-Guzman, Elsa Daniela Zavala-Alvarez","doi":"10.5070/D331164981","DOIUrl":"https://doi.org/10.5070/D331164981","url":null,"abstract":"<p><p>Malignant syphilis, also known as lues maligna, is an atypical and aggressive form of secondary syphilis characterized by nodules and ulcers associated with a spectrum of nonspecific systemic manifestations. The underlying states of immunosuppression represent the primary risk factor. We present a 30-year-old immunocompetent man exhibiting dermatological lesions at various stages clinically and histologically consistent with the established criteria for malignant syphilis. He received antibiotic therapy with complete clearing. Furthermore, we emphasize the importance of proper interpretation of serological tests, both for diagnosis and systematic monitoring.</p>","PeriodicalId":11040,"journal":{"name":"Dermatology online journal","volume":"31 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144316140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}