International Conference on Photonics and Imaging in Biology and Medicine最新文献_第9页

Numerical analysis on RSOD-based phase modulation in OCT 基于rsod的OCT相位调制的数值分析

International Conference on Photonics and Imaging in Biology and Medicine Pub Date : 2007-05-04 DOI: 10.1117/12.741567

Ling Wang, Z. Ding, Kai Wang

引用次数: 0

Quantifying the properties of high scattering media with Mueller matrix 用Mueller矩阵量化高散射介质的性质

International Conference on Photonics and Imaging in Biology and Medicine Pub Date : 2007-05-04 DOI: 10.1117/12.741456

Yong Deng, Q. Lu, Qingming Luo

引用次数: 0

Effect of coherence length and numerical aperture on the formation of OCT signals from model biotissues 相干长度和数值孔径对模型生物组织OCT信号形成的影响

International Conference on Photonics and Imaging in Biology and Medicine Pub Date : 2007-05-04 DOI: 10.1117/12.741129

M. Kirillin, A. Priezzhev, R. Myllyla

{"title":"Effect of coherence length and numerical aperture on the formation of OCT signals from model biotissues","authors":"M. Kirillin, A. Priezzhev, R. Myllyla","doi":"10.1117/12.741129","DOIUrl":"https://doi.org/10.1117/12.741129","url":null,"abstract":"Maximal depth of non-distorted imaging is an important characteristic, which shows the efficiency of an application of a certain OCT setup for imaging the given object. This characteristic depends on the setup parameters and the properties of the studied object. The definition of the maximal depth of non-distorted imaging based on the classifications of photons contributing to the signal in dependence on the relations of their optical travel pathlength in the object and maximal reached depth was used in this work. We studied the effect of the coherence length and the detection angle on the formation of OCT signals and images from model biotissues as well as on the maximal depth of non-distorted imaging. The signals and images were obtained by implementing the Monte Carlo technique developed in our earlier works. The following single- and multilayer biotissue phantoms were considered as the studied objects: erythrocyte suspension at physiological hematocrit (35%), 2% intralipid solution reported to have optical properties close to those of skin in optical and NIR range, and multilayer human skin phantoms. For the simulations, the parameters of the OCT setup were chosen in accordance with real ones. The wavelengths of the light sources were chosen 820 and 910 nm. The conducted simulations show that a decrease in the detection angle and an increase in the coherence length increase the maximal probing depth in the studied objects due to smaller role of multiple scattering photons in the formation of the OCT signals. The obtained value of maximal depth of non-distorted imaging varies in the range from 50 to 600 μm depending on the values of the setup parameters.","PeriodicalId":110373,"journal":{"name":"International Conference on Photonics and Imaging in Biology and Medicine","volume":"7 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2007-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114542325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Effect of LED irradiation on the expression of MMP-3 and MMP-13 in SW1353 cells in vitro LED辐照对SW1353细胞MMP-3和MMP-13表达的影响

International Conference on Photonics and Imaging in Biology and Medicine Pub Date : 2007-05-04 DOI: 10.1117/12.741625

C. Zeng, Zhouyi Guo, Feng-xue Zhang, Wenxia Deng, Song-hao Liu

{"title":"Effect of LED irradiation on the expression of MMP-3 and MMP-13 in SW1353 cells in vitro","authors":"C. Zeng, Zhouyi Guo, Feng-xue Zhang, Wenxia Deng, Song-hao Liu","doi":"10.1117/12.741625","DOIUrl":"https://doi.org/10.1117/12.741625","url":null,"abstract":"Matrix Metalloproteinase (MMP) plays an active role in remodeling cartilage in osteoarthritic cartilage. To find an effective method of prevention of osteoclasia, this in vitro study focuses on the expression of MMP-3 and MMP-13 in the SW1353 cells by LED irradiation. The human chondrosarcoma cell line SW1353 were stimulated with the proinflammatory cytokine IL-1beta or tumor necrosis factor-alpha (TNF-alpha), and were received the irradiation of LED (632nm, 4mW/cm2). The cell count was assessed over a 96-hour period by using Trypan blue dye exclusion assay, and the cell activity was evaluated with a Cell Counting Kit-8 Assays. The subsequent expression of MMP-3 and MMP-13 was quantified. Results of this experiment showed that the cultural cell activity was decreased, and the expression of MMP-3 and MMP-13 was increased by being stimulated with IL-1beta or TNF-alpha. After received LED irradiation, the death rate of cultural cell was increased and the expression of MMP-3 and MMP-13 was decreased significantly. The present study concluded that particular LED irradiation stimulates SW1353 cell proliferation activity and inhibit the MMP-3 and MMP-13 enzymatic activity. These findings might be clinically relevant, indicating that the low power laser irradiation treatment is likely to achieve the repair of articular cartilage in clinic.","PeriodicalId":110373,"journal":{"name":"International Conference on Photonics and Imaging in Biology and Medicine","volume":"38 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2007-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133287409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Numerical analysis on oxygen saturation measurement by dual-wavelength optical low-coherence interferometry 双波长光学低相干干涉测量氧饱和度的数值分析

International Conference on Photonics and Imaging in Biology and Medicine Pub Date : 2007-05-04 DOI: 10.1117/12.741367

Ling Wang, Z. Ding, Lina Huang, M. Geiser

引用次数: 2

Two-photon excited fluorescence imaging of cell spindles for developmental biology 发育生物学中细胞纺锤体的双光子激发荧光成像

International Conference on Photonics and Imaging in Biology and Medicine Pub Date : 2007-05-04 DOI: 10.1117/12.741582

Liang Gao, Wenjia Bai, Lei Jin, P. Xue, Hui Ma, Dieyan Chen

引用次数: 0

Application of fluorescence labeled liposome nanoparticles in the cell imaging 荧光标记纳米脂质体在细胞成像中的应用

International Conference on Photonics and Imaging in Biology and Medicine Pub Date : 2007-05-04 DOI: 10.1117/12.741590

Jianbing Hu, Huimin Li, Xiaoxiao He, P. Gong, Kemin Wang, Shouchun Zhang

引用次数: 1

Analysis on interaction effect of terahertz radiation with living biology system 太赫兹辐射与生物系统相互作用效应分析

International Conference on Photonics and Imaging in Biology and Medicine Pub Date : 2007-05-04 DOI: 10.1117/12.741371

Zhi-Fu Dai, Can-bang Zhang, Sheng-yu Wang, Ling-yun Zhou

引用次数: 3

Study on the cerebrovascular reserve capacity by MR perfusion weighted imaging in SHR 磁共振灌注加权成像对SHR患者脑血管储备容量的研究

International Conference on Photonics and Imaging in Biology and Medicine Pub Date : 2007-05-04 DOI: 10.1117/12.741444

Quan Zhou, Yang Dong, Wenli Chen, Xueying Lin, D. Xing, Li Huang

{"title":"Study on the cerebrovascular reserve capacity by MR perfusion weighted imaging in SHR","authors":"Quan Zhou, Yang Dong, Wenli Chen, Xueying Lin, D. Xing, Li Huang","doi":"10.1117/12.741444","DOIUrl":"https://doi.org/10.1117/12.741444","url":null,"abstract":"Cerebrovascular disease is one of the leading causes of death, and approximately 50% of survivors have a residual neurologic deficit and greater than 25% require chronic care. Cerebrovascular reserve capacity (CVRC) describes how far cerebral perfusion can increase from a baseline value after stimulation. High blood pressure is the most important independent risk factor for stroke and other vascular diseases. The incidence of stroke in the hypertensive is six times higher than in the patient with normal blood pressure. CVRC in the hypertensive was even lower than in control patients. MR perfusion weighted imaging (MR PWI) with the well-established acetazolamide (ACZ) stimulation test has been used for assessing brain function. The aim of this work is to assess the cerebrovascular reserve capacity by MR PWI with \"ACZ\" tolerance test in spontaneous hypertensive rat (SHR) and to identify its value in evaluating the CVRC. Experimental animal including 3 groups: Wistar-Kyoto rats (WKY) (12-week-old) as control group, SHR (12-week-old and 20-week-old) as experimental group. MR PWI was performed respectively before and after acetazolamide administrated orally in 3 groups on a clinical 1.5 Tesla GE Signa MR fx/i whole-body MR system. The ROI was chosen in the bilateral frontal lobe to measure the value of rCBV, rCBF and MTT. The results showed that before ACZ-test, there was statistic differences between the WKY and SHR(12-week-old), and between SHR(12-week-old) and SHR(20-week-old) in the values of rCBV and rCBF (P>0.05), and after ACZ-test, there were statistic differences between WKY and SHR (20-week-old), and between SHR(12-week-old) and SHR(20-week-old) in the rCBV value (P<0.05). It is concluded that the method of MRI PWI combined with the \"ACZ stress test\" can provide more qualitative and half-quantitative information on the cerebral perfusion to evaluate the CVRC in SHR.","PeriodicalId":110373,"journal":{"name":"International Conference on Photonics and Imaging in Biology and Medicine","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2007-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115274633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Distribution and photobleaching of photosensitizer chlorophyll derivative (CPD) in SMCF7 cancer cells 光敏剂叶绿素衍生物(CPD)在SMCF7癌细胞中的分布和光漂白

International Conference on Photonics and Imaging in Biology and Medicine Pub Date : 2007-05-04 DOI: 10.1117/12.741306

Lie Lin, Ping Chen, Kun Zhang, Yan Liu, G. Tang

引用次数: 2