Current Traditional Medicine最新文献_第8页

Marine Biomaterials for Pharmaceutical Applications: A Review 海洋生物材料在医药领域的应用综述

Current Traditional Medicine Pub Date : 2023-08-01 DOI: 10.2174/2215083808666220422094621

Yogesh Murti, Bhupesh Chander Semwal, Sonia Singh

{"title":"Marine Biomaterials for Pharmaceutical Applications: A Review","authors":"Yogesh Murti, Bhupesh Chander Semwal, Sonia Singh","doi":"10.2174/2215083808666220422094621","DOIUrl":"https://doi.org/10.2174/2215083808666220422094621","url":null,"abstract":"Background: Marine ecosystem is one of the main natural sources of numerous biologically active components along with rich biodiversity. Marine biomaterials obtained from fungi, algae, bacteria, and fish, are considered promising candidates for providing various biological as well as biomedical application(s). Objective: The main focused objective of this manuscript is to take out the recent trends utilized in several marine-based biomaterials developed for pharmaceutical applications. Method: The literature contains valuable and collective information on the different bioactivities of marine-based biomaterials. A total of 287 articles are cited in the present review covering a broad spectrum of marine biomaterials, and their pharmaceutical importance. Information of different marine biomaterials along with their source, chemical nature, and pharmaceutical importance are exhaustively compiled here. Results: Marine-based biomaterials possess a wide range of physiochemical activities and modifications in these properties can also enhance the therapeutic and regenerative capacity. Marine biomaterials have proven a good source for the development of different areas of the pharmaceutical field and still, the application of marine biomaterials is going through revitalization in the biomedical field. Conclusion: Due to the amazing diversity involved in marine life, there would be more significant and remarked discoveries developed in the field of marine biomaterials in respect of future implementation in the pharmaceutical arena.","PeriodicalId":11026,"journal":{"name":"Current Traditional Medicine","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134951517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A review on anti-leishmanial activity of terpenes and chitosan as a carrier for nano-formulations 以萜烯和壳聚糖为载体的纳米制剂抗利什曼原虫活性研究进展

IF 0.6

Current Traditional Medicine Pub Date : 2023-07-27 DOI: 10.2174/2215083810666230727094905

Deepali Bansode, Tanvi Goel

{"title":"A review on anti-leishmanial activity of terpenes and chitosan as a carrier for nano-formulations","authors":"Deepali Bansode, Tanvi Goel","doi":"10.2174/2215083810666230727094905","DOIUrl":"https://doi.org/10.2174/2215083810666230727094905","url":null,"abstract":"\u0000\u0000Leishmaniasis is one of the most devastating and fatal diseases in humans that has been known to mankind and is caused by the parasite Leishmania. It is destructive since no vaccination is available and existing medicines are proving ineffective because of resistance development. \u0000A need for the discovery of newer drugs has emerged. The use of natural products for the prevention, diagnosis, and cure of diseases has rapidly increased. Following the trend, research in the field of natural products for treating leishmaniasis has also picked up. In the present review, the focus is on terpenes as anti-leishmanial agents. Terpenes are the least studied natural products for the treatment of the disease. The other part of the review covers the use of chitosan as an anti-leishmanial agent and other formulations of chitosan as a carrier in nano-formulations. \u0000From the survey, it was found that the essential oils containing terpenes are very effective. Moreover, the chitosan-based nanocarriers showed potent anti-leishmanial activity. The combined use of natural products and newer technologies for the delivery of drugs can eradicate various diseases.\u0000","PeriodicalId":11026,"journal":{"name":"Current Traditional Medicine","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48416353","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Review of Modern and Traditional Approaches for the Management of Pulmonary Hypertension 肺动脉高压的现代与传统治疗方法综述

IF 0.6

Current Traditional Medicine Pub Date : 2023-07-12 DOI: 10.2174/2215083810666230712091733

Anuradha Verma, Anshika Garg, Sultan Ahmad, Saquib Haider, B. Kumar, Ritu Chauhan, Manish K. Singh, SambhuCharan Mondal

{"title":"A Review of Modern and Traditional Approaches for the Management of Pulmonary Hypertension","authors":"Anuradha Verma, Anshika Garg, Sultan Ahmad, Saquib Haider, B. Kumar, Ritu Chauhan, Manish K. Singh, SambhuCharan Mondal","doi":"10.2174/2215083810666230712091733","DOIUrl":"https://doi.org/10.2174/2215083810666230712091733","url":null,"abstract":"\u0000\u0000Hypertension, either high blood pressure or pulmonary hypertension, both affect the life of patients in many ways.\u0000\u0000\u0000\u0000Does Pulmonary hypertension similar to high blood pressure?\u0000Does it affect old age people or the neonatal age groups also?\u0000What were the reasons for pulmonary hypertension?\u0000Does pulmonary hypertension manageable with modern and traditional drugs?\u0000\u0000\u0000\u0000The purpose of the literature review is to identify the targeted therapy for pulmonary hypertension and also include the plants that may be effective for the management of pulmonary hypertension.\u0000\u0000\u0000\u0000The author has reviewed many targeted drugs that are presently used, and many are in research that was found effective in making the life of patients as normal as possible.\u0000They also reviewed about 15 herbal plants which were found effective in the management of the disease. \u0000As pulmonary hypertension is not treatable, it can only be managed by changing lifestyle and food habits; therefore, the authors emphasized reviewing the traditional approach for the management of pulmonary hypertension.\u0000","PeriodicalId":11026,"journal":{"name":"Current Traditional Medicine","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42261260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

In silico study of the structural disruption of 14α-demethylase induced by the binding of Terminalia chebula constituents 天竺葵成分结合诱导14α-去甲基化酶结构破坏的硅片研究

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Current Traditional Medicine Pub Date : 2023-07-10 DOI: 10.2174/2215083810666230710122114

N. Rani, Randhir Dahiya, Praveen Kumar, Nandini Verma

引用次数: 0

Therapeutic Potential of Indian Medicinal Herbs and Current Therapeutic Approach Used to Mitigate the Symptoms of Chronic Fatigue Syndrome: A Review 印度草药的治疗潜力和目前用于缓解慢性疲劳综合征症状的治疗方法:综述

IF 0.6

Current Traditional Medicine Pub Date : 2023-06-26 DOI: 10.2174/2215083810666230626115456

R. Sharma, Nisha Singh, A. Kushwah, Manish Kumar

{"title":"Therapeutic Potential of Indian Medicinal Herbs and Current Therapeutic Approach Used to Mitigate the Symptoms of Chronic Fatigue Syndrome: A Review","authors":"R. Sharma, Nisha Singh, A. Kushwah, Manish Kumar","doi":"10.2174/2215083810666230626115456","DOIUrl":"https://doi.org/10.2174/2215083810666230626115456","url":null,"abstract":"\u0000\u0000Chronic fatigue syndrome (CFS) is a complex condition marked by severe exhaustion that lasts at least 6 months. The global prevalence of CFS ranging between 0.4% and 2.5% is growing. Women are affected by CFS more often than men. It is considered a common condition in developed countries. There is no approved treatment for CFS but symptoms can be managed and controlled persistent exhaustion causes significant impairment in daily routine activities. Lowered ATP synthesis, mitochondrial impairment, decreased oxidative phosphorylation, disruption of the hypothalamic–pituitary–adrenal (HPA) axis, and an imbalance of brain neurotransmitters play a major role in the pathophysiology of CFS. The purpose of the present study is to figure out the several plants that are used as a source of medication in chronic fatigue syndrome (CFS) and its current therapeutic approach. The Indian medicinal herbs described in this article are very efficacious in the management of chronic fatigue syndrome symptoms due to the presence of phytochemicals. This review article also covers the current therapeutic approach for chronic fatigue syndrome in a concise form that comprises CBT (Cognitive based therapy), GET (Graded exercise therapy), usage of immunoglobins, psychodynamic counseling, and yoga therapy that includes isometric yoga and yoga nidra are very beneficial in alleviating the symptoms of chronic fatigue syndrome. Antidepressants, immunomodulatory agents, and corticosteroids come under conventional medication for CFS. This article explores different Indian medicinal herbs, their pharmacological properties, and their potential role and current treatments for reducing the severity of symptoms of chronic fatigue syndrome.\u0000","PeriodicalId":11026,"journal":{"name":"Current Traditional Medicine","volume":"1 1","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68187760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Therapeutic Approach of Phytomedicine for Dementia: A Review 植物药物治疗痴呆的研究进展

IF 0.6

Current Traditional Medicine Pub Date : 2023-06-23 DOI: 10.2174/2215083810666230623160622

Sonia Singh, Nikhil Gupta

引用次数: 0

A recent update on Ayurvedic anti-asthmatic formulations: Highlighting the role of major anti-asthmatic plants 阿育吠陀平喘制剂的最新进展：强调主要平喘植物的作用

IF 0.6

Current Traditional Medicine Pub Date : 2023-06-22 DOI: 10.2174/2215083810666230622111859

Jasmine Chaudhary, M. Bhatia, Akash Jain, Sonam, A. Dhingra, B. Chopra

{"title":"A recent update on Ayurvedic anti-asthmatic formulations: Highlighting the role of major anti-asthmatic plants","authors":"Jasmine Chaudhary, M. Bhatia, Akash Jain, Sonam, A. Dhingra, B. Chopra","doi":"10.2174/2215083810666230622111859","DOIUrl":"https://doi.org/10.2174/2215083810666230622111859","url":null,"abstract":"\u0000\u0000Asthma is a chronic heterogeneous airway obstruction disorder defined by a complex cascade of pathophysiological conditions that lead to recurring bronchial hyper-responsiveness and underlying inflammation, lowering the patient’s quality of life. Despite the availability of various synthetic medications for the management of asthma, it has become one of the leading causes of death worldwide. Furthermore, the present allopathic treatment possesses severe long-term negative effects, which make people more attracted to the safer and easily available indigenous traditional and Ayurvedic system of medicine. Ayurveda is regarded as the “Mother of all healing” and “Science of Life,” which treats all the ailments, including asthma, by restoring a balance between three main components of the body- Vata, Pitta, and Dosha. Various clinically effective and less toxic anti-asthmatic Ayurvedic herbal preparations are available for the management of asthma and related complications which act by causing mast cell deactivation, inhibition of Th1, Th2, Th7 response, T-cell suppression, etc., therefore, efforts have been made to compile all the relevant literature related to the ayurvedic anti-asthmatic formulations and scrutinize the efficacy of selected plants present in the majority in those formulations in asthma along with the structure and mode of action of phytoconstituent responsible for designing novel molecules with better efficacy. Research on these selected plants can also have economic significance as various constituents isolated from these plants for their anti-asthmatic effect can further be explored to discover their potential in medicinal, diagnostic and cosmetic field.\u0000","PeriodicalId":11026,"journal":{"name":"Current Traditional Medicine","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43560128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Herbs for the Therapy of Diabetes Mellitus: A Thorough Analysis with Particular Emphasis on Preclinical, Clinical Trials, and their Hypothesised Mechanisms 治疗糖尿病的草药：全面分析，特别强调临床前、临床试验及其假设机制

IF 0.6

Current Traditional Medicine Pub Date : 2023-06-13 DOI: 10.2174/2215083810666230613091337

P. Wal, Namra Aziz, Anushka Verma, Sunil Kumar, H. B. Samal

{"title":"Herbs for the Therapy of Diabetes Mellitus: A Thorough Analysis with Particular Emphasis on Preclinical, Clinical Trials, and their Hypothesised Mechanisms","authors":"P. Wal, Namra Aziz, Anushka Verma, Sunil Kumar, H. B. Samal","doi":"10.2174/2215083810666230613091337","DOIUrl":"https://doi.org/10.2174/2215083810666230613091337","url":null,"abstract":"\u0000\u0000In recent times, herbal medicines have experienced an expansion in both developing and developed countries due to their natural origin and low incidence of adverse effects. A systematic review was performed to gather information regarding herbal plants used to treat diabetes mellitus.\u0000\u0000\u0000\u0000The aim of this article was to review evidence from preclinical and clinical trials and the proposed mechanism of herbal drugs in diabetes mellitus.\u0000\u0000\u0000\u0000A literature survey was carried out mainly focused on scientific papers published in recent years. The search strategy involved interrelated keywords, like “Diabetes mellitus,” “Herbs,” “Hyperglycaemia,” and other uniterms. Electronic databases used were Scopus, Web of Science, PubMed, and Elsevier.\u0000\u0000\u0000\u0000Twenty studies, including preclinical and clinical trials, were selected for evaluating the mechanism of the anti-hyperglycaemic effect of herbal drugs in diabetes mellitus.\u0000\u0000\u0000\u0000Through clinical and preclinical research as well as an analysis of the mechanism of action of herbs, the current review provides preliminary evidence for possible anti-diabetic benefits of herbal medicines.\u0000","PeriodicalId":11026,"journal":{"name":"Current Traditional Medicine","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47984882","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Murraya koenigii (Curry tree): A review of its Phytochemistry, Ethnomedicinal uses, and Pharmacology with Respect to Molecular Mechanisms 咖喱树(Murraya koenigii):其植物化学、民族医药用途和分子机制方面的药理学综述

IF 0.6

Current Traditional Medicine Pub Date : 2023-06-09 DOI: 10.2174/2215083810666230609163404

Deepa S. Mandlik, R. Patil, S. Mandlik

{"title":"Murraya koenigii (Curry tree): A review of its Phytochemistry, Ethnomedicinal uses, and Pharmacology with Respect to Molecular Mechanisms","authors":"Deepa S. Mandlik, R. Patil, S. Mandlik","doi":"10.2174/2215083810666230609163404","DOIUrl":"https://doi.org/10.2174/2215083810666230609163404","url":null,"abstract":"\u0000\u0000Medicinal plants have significant therapeutic value and are a gift to humanity in pursuing healthy living. The discovery of numerous rejuvenating compounds that can stop or reduce the pathology of many diseases will be a crucial advancement in the coming years. Synthetic compounds can cause health issues and side effects, necessitating the development of molecules derived from plants and other natural resources as viable substitutes for synthetic compounds. Several plant phytochemicals and extracts have been found to have significant effects on traditional medical therapy. Murraya koenigii (M. Koenigii) is a member of the Rutaceae family, well-known in the Ayurvedic system of medicine as a therapeutically important herb of Indian origin. M. Koenigii has been used in several ancient systems of medicine, including Siddha and Unani, as a multi-potential medicinal plant. Previous research has shown that this plant's bark, roots, and leaves are abundant sources of carbazole alkaloids, which have beneficial pharmacological and biological effects. These include antioxidant, antibacterial, antidiabetic, anti-inflammatory, antihypertensive, antifungal, antiprotozoal, hepatoprotective, anti-hypercholesterolemic, antiulcer, cytotoxic, antidiarrheal, phagocytic, neuroprotective, and antitumor activities. The key components of the M. koenigii plant and their pharmacological activities against various diseases using preclinical models are discussed in this review. Exhaustive studies on the molecular mechanism of action of M. koenigii are needed to validate the effectiveness of curry tree and their constituents as potent therapeutic agents. However, serious efforts are required to identify, isolate and evaluate the chemical components for nutritional and medicinal potentials.\u0000","PeriodicalId":11026,"journal":{"name":"Current Traditional Medicine","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43958653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Biological importance and therapeutic potential of delicaflavone against cancerous disorders: A rare naturally occurring biflavonoids of Selaginella species delicaflavone对癌症疾病的生物学重要性和治疗潜力：一种罕见的卷柏属天然双黄酮类化合物

IF 0.6

Current Traditional Medicine Pub Date : 2023-06-08 DOI: 10.2174/2215083810666230608104601

D. Patel

引用次数: 0