Current Traditional Medicine最新文献_第7页

A Concise Review on Therapeutic Potential, Phytochemistry and Traditional Applications of Safed Musli (Chlorophytum borivilianum) 安全吊兰(吊兰)的治疗潜力、植物化学和传统应用综述

IF 0.6

Current Traditional Medicine Pub Date : 2023-08-09 DOI: 10.2174/2215083810666230809103444

Raghav Mishra, P. Dhakad, Isha Mishra, Vikram Sharma

{"title":"A Concise Review on Therapeutic Potential, Phytochemistry and Traditional Applications of Safed Musli (Chlorophytum borivilianum)","authors":"Raghav Mishra, P. Dhakad, Isha Mishra, Vikram Sharma","doi":"10.2174/2215083810666230809103444","DOIUrl":"https://doi.org/10.2174/2215083810666230809103444","url":null,"abstract":"\u0000\u0000In traditional medicine, Safed musli is a very popular herb. Natural sex tonics like Chlorophytum borivilianum (C. borivilianum) are effective in alleviating sexual disorders. Local healers in indigenous communities of India mostly use it for ethnic medicine. The circulation of blood is one of the functions it improves to enhance strength and energy. Since ancient times, the tuber roots of the plant Safed musli have been used to treat weakness and male impotency.\u0000\u0000\u0000\u0000The aim of this work is to bridge the scientific evidence with the pharmacological, phytochemical, and folkloric claims reported in different sources belonging to C. borivilianum.\u0000\u0000\u0000\u0000To build the manuscript, a detailed literature review was carried out by thoroughly analyzing globally accepted scientific research databases.\u0000\u0000\u0000\u0000Safed musli is widely recognized for its efficacy in addressing male impotence. The abundant presence of phytoconstituents, particularly saponins, contributes to the nutritional and multifaceted therapeutic significance of C. borivilianum.\u0000\u0000\u0000\u0000The current review enlightens the pharmacotherapeutic potential of C. borivilianum, comprising its origin and distribution, botany, proximate composition, method of enhancing seed germination, pathology, phytochemistry, pharmacology, and traditional uses. The scope for future research is provided by the present review, which also furnishes a gateway for filling the existing gap in its various aspects of investigation.\u0000","PeriodicalId":11026,"journal":{"name":"Current Traditional Medicine","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42095122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A REVIEW: Ophiocordycep Sinensis (Berk.) as a Traditional TibetanMedicine and its Potential in the Treatment of Various Human Ailments Ophiocordycep Sinensis（Berk.）作为一种传统藏医药及其在治疗各种人类疾病中的潜力综述

IF 0.6

Current Traditional Medicine Pub Date : 2023-08-07 DOI: 10.2174/2215083810666230807155214

Yangchen Dolma Kom, R. Karthiyayini

引用次数: 0

Bacoside A: A Promising Medication for Treatment of Various Disorders Bacoside A：一种治疗各种疾病的有前景的药物

IF 0.6

Current Traditional Medicine Pub Date : 2023-08-04 DOI: 10.2174/2215083810666230804095036

Keshav Bansal, Vanshita, M. Bajpai

引用次数: 0

Herbal Remedies: An Emerging Alternative for the Treatment of Pandemic Diseases 草药疗法：治疗流行病的新选择

IF 0.6

Current Traditional Medicine Pub Date : 2023-08-03 DOI: 10.2174/2215083810666230803101424

N. T. Nistane, Mayur B. Kale, R. Das, Mohit Umare, M. Umekar, A. Hemke, Vishal R. Gajbhiye

{"title":"Herbal Remedies: An Emerging Alternative for the Treatment of Pandemic Diseases","authors":"N. T. Nistane, Mayur B. Kale, R. Das, Mohit Umare, M. Umekar, A. Hemke, Vishal R. Gajbhiye","doi":"10.2174/2215083810666230803101424","DOIUrl":"https://doi.org/10.2174/2215083810666230803101424","url":null,"abstract":"\u0000\u0000Pandemics are large-scale epidemics of infectious illness that may cause major economical, cultural, and political upheaval while also increasing illness and mortality across a huge geographic area. Evidence shows that pandemics have increased during the last century as a result of increasing international travel and connectivity, industrialization, agricultural expansion, and higher destruction of the natural environment. Over time, emerging pathogen strains cause pandemics that raise suffering, death, and instability in countries. Flu, plague, cholera, HIV, and the current COVID-19 pandemic caused by a novel coronavirus are just a few of the pathogen outbreaks. Unfortunately, given the lack of information and instruments to tackle the problem, managing new and developing infections is frequently challenging. Yet, the use of herbal remedies to treat new and developing infectious illnesses has received much interest. Until the invention of antibiotics, herbal plants, their preparations, and extracted phytoconstituents were reported to be efficient in reducing infectious diseases. Plants contain numerous complex metabolites, such as amino acids, alkaloids, tannins, flavonoids, terpenoids, and glycosides, that show different therapeutic activities. This review provides vital and useful information regarding herbal drugs and their effectiveness against various pathogens that cause major pandemics.\u0000","PeriodicalId":11026,"journal":{"name":"Current Traditional Medicine","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41991155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Natural Flavonoids as an Intervention for Hepatic Encephalopathy: Pre-clinical Evidence-based Review 天然黄酮类化合物对肝性脑病的干预作用：临床前循证医学综述

IF 0.6

Current Traditional Medicine Pub Date : 2023-08-03 DOI: 10.2174/2215083810666230803093156

Niraj Kumar Singh, Ashutosh Solanki

{"title":"Natural Flavonoids as an Intervention for Hepatic Encephalopathy: Pre-clinical Evidence-based Review","authors":"Niraj Kumar Singh, Ashutosh Solanki","doi":"10.2174/2215083810666230803093156","DOIUrl":"https://doi.org/10.2174/2215083810666230803093156","url":null,"abstract":"\u0000\u0000Hepatic encephalopathy (HE) is a serious neuropsychiatric disorder caused in patients with both; acute and chronic liver diseases, which consists of various complications ranging from cognitive impairment, disorientation, confusion, and coma. The available therapies mainly focus on decreasing ammonia levels either through increasing its elimination or decreasing its production, some medications may subside the duration and limit the consequences of HE, but there is no complete available treatment for HE-like manifestation. Thus, there is a need to explore new pharmacotherapy for the treatment and management of HE. Flavonoids are polyphenolic compounds easily found in vegetables, fruits, flowers, beverages, and plants based foods. In modern research, flavonoids have gained attention due to their broad pharmacological properties, like anti-oxidant, anti-viral, anti-inflammatory, cardioprotective, cytoprotective, and neuroprotective activity. Several pre-clinical studies suggest that various flavonoids have a potential therapeutic role in a variety of metabolic-related neurological disorders, including HE. This review focuses on all pre-clinical reports that highlight the neuroprotective potential of natural flavonoids for the management of HE. Based on numerous pre-clinical studies and taking into account the therapeutic effects of natural flavonoids, the present study illustrates the cellular and molecular mechanisms responsible for the potential role of natural flavonoids as pharmacotherapy for the management and treatment of HE.\u0000","PeriodicalId":11026,"journal":{"name":"Current Traditional Medicine","volume":"150 ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41275063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The effectiveness of a poly-herbal formulation from traditional Persian medicine (TPM) in gastroesophageal reflux disease (GERD), a double-blinded randomized clinical trial 一项双盲随机临床试验，波斯传统药物（TPM）多草药制剂治疗胃食管反流病（GERD）的有效性

IF 0.6

Current Traditional Medicine Pub Date : 2023-08-01 DOI: 10.2174/2215083810666230801122931

N. Ebrahimi, Ebrahim Fallahzadeh Abarghooee, A. Vazin, R. Ansari, M. Zarshenas

{"title":"The effectiveness of a poly-herbal formulation from traditional Persian medicine (TPM) in gastroesophageal reflux disease (GERD), a double-blinded randomized clinical trial","authors":"N. Ebrahimi, Ebrahim Fallahzadeh Abarghooee, A. Vazin, R. Ansari, M. Zarshenas","doi":"10.2174/2215083810666230801122931","DOIUrl":"https://doi.org/10.2174/2215083810666230801122931","url":null,"abstract":"\u0000\u0000Gastroesophageal reflux disease (GERD) leads to increased contact of the acidic refluxate with the esophageal mucosa. Nearly 10- 20 % of the world's population is affected by GERD. Due to the complications associated with GERD, as well as complications of long-term treatment with current medications, and global demand toward Complementary and Alternative Medicine (CAM), this study evaluated the efficacy of a poly-herbal formulation known as Mastic pill (Habb-e-Mastaki) from traditional Persian medicine (TPM), previously reformulated and standardized, in a double-blinded randomized clinical trial.\u0000\u0000\u0000\u000034 patients in the drug group received 4 capsules of Mastic pill plus Omeprazole capsule 20 mg daily. 34 patients in the placebo group received the same dosing of Omeprazole and placebo. The medication was given to patients for a total duration of 4 weeks. All patients were requested to fill out the modified GERD-HRQL questionnaire at the beginning and every two weeks for a total duration of six weeks.\u0000\u0000\u0000\u0000Reflux, and heartburn severity score as well as disruption of personal life score significantly reduced in both groups, but it was more remarkable in the drug group (P-value = 0.0001). Dysphagia, early satiation, and nausea significantly reduced in the drug group while the placebo group showed no improvement. Our results suggest that constipation, bloating, belching, and odynophagia did not significantly improve in none of the groups.\u0000\u0000\u0000\u0000This study showed that Habb-e-Mastaki is effective against GERD. Further detailed in vitro and in vivo studies aimed at discovering the mechanism of action of this formulation and clinical studies involving a larger population will be necessary to explain and confirm the results obtained in the present study.\u0000","PeriodicalId":11026,"journal":{"name":"Current Traditional Medicine","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44272052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Marine Biomaterials for Pharmaceutical Applications: A Review 海洋生物材料在医药领域的应用综述

Current Traditional Medicine Pub Date : 2023-08-01 DOI: 10.2174/2215083808666220422094621

Yogesh Murti, Bhupesh Chander Semwal, Sonia Singh

{"title":"Marine Biomaterials for Pharmaceutical Applications: A Review","authors":"Yogesh Murti, Bhupesh Chander Semwal, Sonia Singh","doi":"10.2174/2215083808666220422094621","DOIUrl":"https://doi.org/10.2174/2215083808666220422094621","url":null,"abstract":"Background: Marine ecosystem is one of the main natural sources of numerous biologically active components along with rich biodiversity. Marine biomaterials obtained from fungi, algae, bacteria, and fish, are considered promising candidates for providing various biological as well as biomedical application(s). Objective: The main focused objective of this manuscript is to take out the recent trends utilized in several marine-based biomaterials developed for pharmaceutical applications. Method: The literature contains valuable and collective information on the different bioactivities of marine-based biomaterials. A total of 287 articles are cited in the present review covering a broad spectrum of marine biomaterials, and their pharmaceutical importance. Information of different marine biomaterials along with their source, chemical nature, and pharmaceutical importance are exhaustively compiled here. Results: Marine-based biomaterials possess a wide range of physiochemical activities and modifications in these properties can also enhance the therapeutic and regenerative capacity. Marine biomaterials have proven a good source for the development of different areas of the pharmaceutical field and still, the application of marine biomaterials is going through revitalization in the biomedical field. Conclusion: Due to the amazing diversity involved in marine life, there would be more significant and remarked discoveries developed in the field of marine biomaterials in respect of future implementation in the pharmaceutical arena.","PeriodicalId":11026,"journal":{"name":"Current Traditional Medicine","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134951517","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A review on anti-leishmanial activity of terpenes and chitosan as a carrier for nano-formulations 以萜烯和壳聚糖为载体的纳米制剂抗利什曼原虫活性研究进展

IF 0.6

Current Traditional Medicine Pub Date : 2023-07-27 DOI: 10.2174/2215083810666230727094905

Deepali Bansode, Tanvi Goel

{"title":"A review on anti-leishmanial activity of terpenes and chitosan as a carrier for nano-formulations","authors":"Deepali Bansode, Tanvi Goel","doi":"10.2174/2215083810666230727094905","DOIUrl":"https://doi.org/10.2174/2215083810666230727094905","url":null,"abstract":"\u0000\u0000Leishmaniasis is one of the most devastating and fatal diseases in humans that has been known to mankind and is caused by the parasite Leishmania. It is destructive since no vaccination is available and existing medicines are proving ineffective because of resistance development. \u0000A need for the discovery of newer drugs has emerged. The use of natural products for the prevention, diagnosis, and cure of diseases has rapidly increased. Following the trend, research in the field of natural products for treating leishmaniasis has also picked up. In the present review, the focus is on terpenes as anti-leishmanial agents. Terpenes are the least studied natural products for the treatment of the disease. The other part of the review covers the use of chitosan as an anti-leishmanial agent and other formulations of chitosan as a carrier in nano-formulations. \u0000From the survey, it was found that the essential oils containing terpenes are very effective. Moreover, the chitosan-based nanocarriers showed potent anti-leishmanial activity. The combined use of natural products and newer technologies for the delivery of drugs can eradicate various diseases.\u0000","PeriodicalId":11026,"journal":{"name":"Current Traditional Medicine","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48416353","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Review of Modern and Traditional Approaches for the Management of Pulmonary Hypertension 肺动脉高压的现代与传统治疗方法综述

IF 0.6

Current Traditional Medicine Pub Date : 2023-07-12 DOI: 10.2174/2215083810666230712091733

Anuradha Verma, Anshika Garg, Sultan Ahmad, Saquib Haider, B. Kumar, Ritu Chauhan, Manish K. Singh, SambhuCharan Mondal

{"title":"A Review of Modern and Traditional Approaches for the Management of Pulmonary Hypertension","authors":"Anuradha Verma, Anshika Garg, Sultan Ahmad, Saquib Haider, B. Kumar, Ritu Chauhan, Manish K. Singh, SambhuCharan Mondal","doi":"10.2174/2215083810666230712091733","DOIUrl":"https://doi.org/10.2174/2215083810666230712091733","url":null,"abstract":"\u0000\u0000Hypertension, either high blood pressure or pulmonary hypertension, both affect the life of patients in many ways.\u0000\u0000\u0000\u0000Does Pulmonary hypertension similar to high blood pressure?\u0000Does it affect old age people or the neonatal age groups also?\u0000What were the reasons for pulmonary hypertension?\u0000Does pulmonary hypertension manageable with modern and traditional drugs?\u0000\u0000\u0000\u0000The purpose of the literature review is to identify the targeted therapy for pulmonary hypertension and also include the plants that may be effective for the management of pulmonary hypertension.\u0000\u0000\u0000\u0000The author has reviewed many targeted drugs that are presently used, and many are in research that was found effective in making the life of patients as normal as possible.\u0000They also reviewed about 15 herbal plants which were found effective in the management of the disease. \u0000As pulmonary hypertension is not treatable, it can only be managed by changing lifestyle and food habits; therefore, the authors emphasized reviewing the traditional approach for the management of pulmonary hypertension.\u0000","PeriodicalId":11026,"journal":{"name":"Current Traditional Medicine","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42261260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

In silico study of the structural disruption of 14α-demethylase induced by the binding of Terminalia chebula constituents 天竺葵成分结合诱导14α-去甲基化酶结构破坏的硅片研究

IF 0.6

Current Traditional Medicine Pub Date : 2023-07-10 DOI: 10.2174/2215083810666230710122114

N. Rani, Randhir Dahiya, Praveen Kumar, Nandini Verma

引用次数: 0