Current Traditional Medicine最新文献_第7页

Pharmacological Activities of the Roots of Stemona tuberosa Medicinal Plant: An Overview 药用植物块茎根的药理活性研究综述

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Current Traditional Medicine Pub Date : 2023-08-16 DOI: 10.2174/2215083810666230816095313

Shilpi Pathak, Riya Verma, Richa Sharma

{"title":"Pharmacological Activities of the Roots of Stemona tuberosa Medicinal Plant: An Overview","authors":"Shilpi Pathak, Riya Verma, Richa Sharma","doi":"10.2174/2215083810666230816095313","DOIUrl":"https://doi.org/10.2174/2215083810666230816095313","url":null,"abstract":"\u0000\u0000Since childhood, plants and plant products have been used extensively as medicine. The majority of rural residents still rely on natural resources and the old-fashioned medical system for their daily needs. The biological richness of Arunachal Pradesh is renowned, as is its rich cultural diversity. The native population uses a number of aromatic and medicinal plant species to cure a wide range of illnesses. The current review deals with the biological activity of Stemona tuberosa, a possible medicinal plant species of Arunachal Pradesh. Extract from tuberous roots has numerous properties, including anti-bacterial, anti-inflammatory, anti-tobacco mosaic virus, antitussive, wound healing, and anti-herpes. The roots' powder is employed as a preservation and insect deterrent. Alkaloids, sugars and glycosides, phenolic compounds, trace amounts of proteins, saponin, flavonoids, and gum mucilage, were all found during the phytochemical analysis, which shows that the species has a significant potential for therapeutic use. As a result, it is possible to think of the examined species as a potential source of beneficial medications.\u0000","PeriodicalId":11026,"journal":{"name":"Current Traditional Medicine","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-08-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43861129","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Therapeutic and Health Promoting Potential of Terminalia chebula: An Exploratory Literature Review 查末的治疗和健康促进潜力：文献综述

IF 0.6

Current Traditional Medicine Pub Date : 2023-08-15 DOI: 10.2174/2215083810666230815142547

A. Dhingra, M. Chopra, Geeta Deswal, B. Chopra, P. Kriplani, R. Dass, A. Grewal, V. Rathi

{"title":"Therapeutic and Health Promoting Potential of Terminalia chebula: An Exploratory Literature Review","authors":"A. Dhingra, M. Chopra, Geeta Deswal, B. Chopra, P. Kriplani, R. Dass, A. Grewal, V. Rathi","doi":"10.2174/2215083810666230815142547","DOIUrl":"https://doi.org/10.2174/2215083810666230815142547","url":null,"abstract":"\u0000\u0000The plant Terminalia chebula has been used traditionally in many regions of the world for its therapeutic properties, especially in India. Its therapeutic and health-promoting potential has been recognized for centuries, and modern research continues to unveil its numerous benefits. One of the most significant applications of this plant is its antimicrobial and antioxidant potential. The plant contains high levels of phenolic compounds and flavonoids, which scavenge harmful free radicals in the body, reducing oxidative stress and cellular damage. This antioxidant action contributes to its anti-inflammatory effects, making it beneficial for a wide range of conditions, including arthritis, cardiovascular diseases, and neurodegenerative disorders. Furthermore, Terminalia chebula exhibits antimicrobial activity against various bacteria and fungi, including those responsible for common infections. It has been used to treat respiratory infections, urinary tract infections, and skin ailments. Its broad-spectrum antimicrobial effects make it a valuable natural remedy for combating microbial pathogens. Moreover, Terminalia chebula shows potential in managing diabetes and promoting cardiovascular health. Studies have indicated its ability to regulate blood sugar levels, improve insulin sensitivity, and reduce lipid abnormalities. These properties make it a promising adjunct therapy for individuals with diabetes or at risk of heart disease. In conclusion, Terminalia chebula possesses remarkable therapeutic and health-promoting potential. Its antioxidant, anti-inflammatory, antimicrobial, and digestive benefits make it a valuable natural remedy for various ailments. While research on Terminalia chebula is ongoing, its long-standing use in traditional medicine and emerging scientific evidence solidify its status as a potent medicinal plant with diverse applications in promoting overall well-being.\u0000","PeriodicalId":11026,"journal":{"name":"Current Traditional Medicine","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44740401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nano-based herbal medicine: A new candidate for prostate cancer treatment? 纳米草药：前列腺癌症治疗的新候选药物？

IF 0.6

Current Traditional Medicine Pub Date : 2023-08-15 DOI: 10.2174/2215083810666230815142928

H. Motedayyen, Tayebe Pouryousefi-koodehi, M. S. Kahrizi, Hossein Roghani-Shahraki, Fatemeh Rezaei-Tazangi, Reza Arefnezhad

{"title":"Nano-based herbal medicine: A new candidate for prostate cancer treatment?","authors":"H. Motedayyen, Tayebe Pouryousefi-koodehi, M. S. Kahrizi, Hossein Roghani-Shahraki, Fatemeh Rezaei-Tazangi, Reza Arefnezhad","doi":"10.2174/2215083810666230815142928","DOIUrl":"https://doi.org/10.2174/2215083810666230815142928","url":null,"abstract":"\u0000\u0000Prostate cancer (PCa) is known as the fifth reason for cancer-related deaths and involves a considerable population of men globally. In PCa, pluriform neoplasm with different cancer patterns is formed. Metastases have a substantial role in disease mortality, and lung, liver, and bone are among the common organs for metastasis. In spite of multiple attempts by researchers, it has not been recommended a safe and suitable approach against PCa so far.\u0000\u0000\u0000\u0000Fortunately, herbal remedies have opened a novel window in order to treat several cancers, such as PCa; however, there are some barriers regarding this curative method, like low bioavailability and absorption and low water solubility. On the contrary, some nano-based formulations have revealed a potential ability to overcome these limitations, and it seems that the co-use of herbal products and nanoformulations provides a good opportunity for treating PCa.\u0000\u0000\u0000\u0000In this study, we argued about the therapeutic aspects of some nanoformulations of popular herbal products, such as curcumin, quercetin, and resveratrol, against PCa.\u0000","PeriodicalId":11026,"journal":{"name":"Current Traditional Medicine","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42919133","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Formulation and Development of Clove and Coriander Combination Herbal Dental Anticaries Gel and Evaluation of its Antimicrobial Activity 丁香香菜复方口腔抗菌凝胶的研制及抗菌活性评价

IF 0.6

Current Traditional Medicine Pub Date : 2023-08-10 DOI: 10.2174/2215083810666230810094713

Ganguly Paramita, Kazi Julekha, Mandal Sudip kumar

{"title":"Formulation and Development of Clove and Coriander Combination Herbal Dental Anticaries Gel and Evaluation of its Antimicrobial Activity","authors":"Ganguly Paramita, Kazi Julekha, Mandal Sudip kumar","doi":"10.2174/2215083810666230810094713","DOIUrl":"https://doi.org/10.2174/2215083810666230810094713","url":null,"abstract":"\u0000\u0000Dental caries is one of the Periodontal diseases that has been recognized as a major public health problem for decades throughout the world. It occurs in all groups, ethnicities, races, and genders at all socioeconomic levels. Natural remedies are more acceptable in the belief that they are safer with fewer side effects than synthetic ones. Clove and coriander oil are established herbal drugs for periodontal diseases.\u0000\u0000\u0000\u0000This research work was intended to formulate a dental gel containing clove and Coriander as the major constituents and evaluate it for dental caries treatment. Both of the herbal oils have a vast range of antimicrobial activity against a great number of periodontal pathogens; therefore, they are used for periodontitis treatment.\u0000\u0000\u0000\u0000The combination gel was prepared using carbopol 934 as a gelling agent, clove oil and coriander oil as therapeutic constituents, polyethylene glycol as a co-solvent, methyl paraben and propyl paraben as a preservative and a required quantity of distilled water as vehicle.\u0000\u0000\u0000\u0000The gel was analyzed for various properties like antimicrobial activity, pH, spreadability, extrudability, drug content etc., and it was shown that the combination gel is a satisfactory dosage form that is used in periodontitis treatment. The combination gel revealed the ZI ( zone of inhibition ) of about 22.05±0.04 mm.\u0000\u0000\u0000\u0000The present study concluded that the combination gel preparations of clove oil and coriander oil reported satisfactory physicochemical properties along with good drug content compared to the single gel preparation.\u0000","PeriodicalId":11026,"journal":{"name":"Current Traditional Medicine","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42542845","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Concise Review on Therapeutic Potential, Phytochemistry and Traditional Applications of Safed Musli (Chlorophytum borivilianum) 安全吊兰(吊兰)的治疗潜力、植物化学和传统应用综述

IF 0.6

Current Traditional Medicine Pub Date : 2023-08-09 DOI: 10.2174/2215083810666230809103444

Raghav Mishra, P. Dhakad, Isha Mishra, Vikram Sharma

{"title":"A Concise Review on Therapeutic Potential, Phytochemistry and Traditional Applications of Safed Musli (Chlorophytum borivilianum)","authors":"Raghav Mishra, P. Dhakad, Isha Mishra, Vikram Sharma","doi":"10.2174/2215083810666230809103444","DOIUrl":"https://doi.org/10.2174/2215083810666230809103444","url":null,"abstract":"\u0000\u0000In traditional medicine, Safed musli is a very popular herb. Natural sex tonics like Chlorophytum borivilianum (C. borivilianum) are effective in alleviating sexual disorders. Local healers in indigenous communities of India mostly use it for ethnic medicine. The circulation of blood is one of the functions it improves to enhance strength and energy. Since ancient times, the tuber roots of the plant Safed musli have been used to treat weakness and male impotency.\u0000\u0000\u0000\u0000The aim of this work is to bridge the scientific evidence with the pharmacological, phytochemical, and folkloric claims reported in different sources belonging to C. borivilianum.\u0000\u0000\u0000\u0000To build the manuscript, a detailed literature review was carried out by thoroughly analyzing globally accepted scientific research databases.\u0000\u0000\u0000\u0000Safed musli is widely recognized for its efficacy in addressing male impotence. The abundant presence of phytoconstituents, particularly saponins, contributes to the nutritional and multifaceted therapeutic significance of C. borivilianum.\u0000\u0000\u0000\u0000The current review enlightens the pharmacotherapeutic potential of C. borivilianum, comprising its origin and distribution, botany, proximate composition, method of enhancing seed germination, pathology, phytochemistry, pharmacology, and traditional uses. The scope for future research is provided by the present review, which also furnishes a gateway for filling the existing gap in its various aspects of investigation.\u0000","PeriodicalId":11026,"journal":{"name":"Current Traditional Medicine","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42095122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A REVIEW: Ophiocordycep Sinensis (Berk.) as a Traditional TibetanMedicine and its Potential in the Treatment of Various Human Ailments Ophiocordycep Sinensis（Berk.）作为一种传统藏医药及其在治疗各种人类疾病中的潜力综述

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Current Traditional Medicine Pub Date : 2023-08-07 DOI: 10.2174/2215083810666230807155214

Yangchen Dolma Kom, R. Karthiyayini

引用次数: 0

Bacoside A: A Promising Medication for Treatment of Various Disorders Bacoside A：一种治疗各种疾病的有前景的药物

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Current Traditional Medicine Pub Date : 2023-08-04 DOI: 10.2174/2215083810666230804095036

Keshav Bansal, Vanshita, M. Bajpai

引用次数: 0

Herbal Remedies: An Emerging Alternative for the Treatment of Pandemic Diseases 草药疗法：治疗流行病的新选择

IF 0.6

Current Traditional Medicine Pub Date : 2023-08-03 DOI: 10.2174/2215083810666230803101424

N. T. Nistane, Mayur B. Kale, R. Das, Mohit Umare, M. Umekar, A. Hemke, Vishal R. Gajbhiye

{"title":"Herbal Remedies: An Emerging Alternative for the Treatment of Pandemic Diseases","authors":"N. T. Nistane, Mayur B. Kale, R. Das, Mohit Umare, M. Umekar, A. Hemke, Vishal R. Gajbhiye","doi":"10.2174/2215083810666230803101424","DOIUrl":"https://doi.org/10.2174/2215083810666230803101424","url":null,"abstract":"\u0000\u0000Pandemics are large-scale epidemics of infectious illness that may cause major economical, cultural, and political upheaval while also increasing illness and mortality across a huge geographic area. Evidence shows that pandemics have increased during the last century as a result of increasing international travel and connectivity, industrialization, agricultural expansion, and higher destruction of the natural environment. Over time, emerging pathogen strains cause pandemics that raise suffering, death, and instability in countries. Flu, plague, cholera, HIV, and the current COVID-19 pandemic caused by a novel coronavirus are just a few of the pathogen outbreaks. Unfortunately, given the lack of information and instruments to tackle the problem, managing new and developing infections is frequently challenging. Yet, the use of herbal remedies to treat new and developing infectious illnesses has received much interest. Until the invention of antibiotics, herbal plants, their preparations, and extracted phytoconstituents were reported to be efficient in reducing infectious diseases. Plants contain numerous complex metabolites, such as amino acids, alkaloids, tannins, flavonoids, terpenoids, and glycosides, that show different therapeutic activities. This review provides vital and useful information regarding herbal drugs and their effectiveness against various pathogens that cause major pandemics.\u0000","PeriodicalId":11026,"journal":{"name":"Current Traditional Medicine","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41991155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Natural Flavonoids as an Intervention for Hepatic Encephalopathy: Pre-clinical Evidence-based Review 天然黄酮类化合物对肝性脑病的干预作用：临床前循证医学综述

IF 0.6

Current Traditional Medicine Pub Date : 2023-08-03 DOI: 10.2174/2215083810666230803093156

Niraj Kumar Singh, Ashutosh Solanki

{"title":"Natural Flavonoids as an Intervention for Hepatic Encephalopathy: Pre-clinical Evidence-based Review","authors":"Niraj Kumar Singh, Ashutosh Solanki","doi":"10.2174/2215083810666230803093156","DOIUrl":"https://doi.org/10.2174/2215083810666230803093156","url":null,"abstract":"\u0000\u0000Hepatic encephalopathy (HE) is a serious neuropsychiatric disorder caused in patients with both; acute and chronic liver diseases, which consists of various complications ranging from cognitive impairment, disorientation, confusion, and coma. The available therapies mainly focus on decreasing ammonia levels either through increasing its elimination or decreasing its production, some medications may subside the duration and limit the consequences of HE, but there is no complete available treatment for HE-like manifestation. Thus, there is a need to explore new pharmacotherapy for the treatment and management of HE. Flavonoids are polyphenolic compounds easily found in vegetables, fruits, flowers, beverages, and plants based foods. In modern research, flavonoids have gained attention due to their broad pharmacological properties, like anti-oxidant, anti-viral, anti-inflammatory, cardioprotective, cytoprotective, and neuroprotective activity. Several pre-clinical studies suggest that various flavonoids have a potential therapeutic role in a variety of metabolic-related neurological disorders, including HE. This review focuses on all pre-clinical reports that highlight the neuroprotective potential of natural flavonoids for the management of HE. Based on numerous pre-clinical studies and taking into account the therapeutic effects of natural flavonoids, the present study illustrates the cellular and molecular mechanisms responsible for the potential role of natural flavonoids as pharmacotherapy for the management and treatment of HE.\u0000","PeriodicalId":11026,"journal":{"name":"Current Traditional Medicine","volume":"150 ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41275063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The effectiveness of a poly-herbal formulation from traditional Persian medicine (TPM) in gastroesophageal reflux disease (GERD), a double-blinded randomized clinical trial 一项双盲随机临床试验，波斯传统药物（TPM）多草药制剂治疗胃食管反流病（GERD）的有效性

IF 0.6

Current Traditional Medicine Pub Date : 2023-08-01 DOI: 10.2174/2215083810666230801122931

N. Ebrahimi, Ebrahim Fallahzadeh Abarghooee, A. Vazin, R. Ansari, M. Zarshenas

{"title":"The effectiveness of a poly-herbal formulation from traditional Persian medicine (TPM) in gastroesophageal reflux disease (GERD), a double-blinded randomized clinical trial","authors":"N. Ebrahimi, Ebrahim Fallahzadeh Abarghooee, A. Vazin, R. Ansari, M. Zarshenas","doi":"10.2174/2215083810666230801122931","DOIUrl":"https://doi.org/10.2174/2215083810666230801122931","url":null,"abstract":"\u0000\u0000Gastroesophageal reflux disease (GERD) leads to increased contact of the acidic refluxate with the esophageal mucosa. Nearly 10- 20 % of the world's population is affected by GERD. Due to the complications associated with GERD, as well as complications of long-term treatment with current medications, and global demand toward Complementary and Alternative Medicine (CAM), this study evaluated the efficacy of a poly-herbal formulation known as Mastic pill (Habb-e-Mastaki) from traditional Persian medicine (TPM), previously reformulated and standardized, in a double-blinded randomized clinical trial.\u0000\u0000\u0000\u000034 patients in the drug group received 4 capsules of Mastic pill plus Omeprazole capsule 20 mg daily. 34 patients in the placebo group received the same dosing of Omeprazole and placebo. The medication was given to patients for a total duration of 4 weeks. All patients were requested to fill out the modified GERD-HRQL questionnaire at the beginning and every two weeks for a total duration of six weeks.\u0000\u0000\u0000\u0000Reflux, and heartburn severity score as well as disruption of personal life score significantly reduced in both groups, but it was more remarkable in the drug group (P-value = 0.0001). Dysphagia, early satiation, and nausea significantly reduced in the drug group while the placebo group showed no improvement. Our results suggest that constipation, bloating, belching, and odynophagia did not significantly improve in none of the groups.\u0000\u0000\u0000\u0000This study showed that Habb-e-Mastaki is effective against GERD. Further detailed in vitro and in vivo studies aimed at discovering the mechanism of action of this formulation and clinical studies involving a larger population will be necessary to explain and confirm the results obtained in the present study.\u0000","PeriodicalId":11026,"journal":{"name":"Current Traditional Medicine","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44272052","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0