Current Traditional Medicine最新文献

{"title":"Hemorrhoid (pile) and its treatment with botanicals: An overview","authors":"Ajay Kumar Shukla, Manoj Kumar Mishra","doi":"10.2174/2215083810666230915103508","DOIUrl":"https://doi.org/10.2174/2215083810666230915103508","url":null,"abstract":"Abstract: Hemorrhoid disease is a common condition that can have a significant impact on an individual's quality of life due to its associated symptoms. A wide range of management options are available for the treatment of hemorrhoid disease, including various yogic kriyas, herbal remedies, flavonoids, tocotrienols, topical treatments, hydrotherapy, dietary approaches, and surgical procedures. This review aims to focus specifically on the use of botanicals for the treatment of hemorrhoid disease, covering various aspects of its treatment.","PeriodicalId":11026,"journal":{"name":"Current Traditional Medicine","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135485368","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unani approach to graded management of thrombosis in Covid-19 patients","authors":"Zikra Tahseen. A, Ghulamuddin Sofi, Arisha Shahid, None Sofia, Shahila Aazam","doi":"10.2174/2215083810666230914103404","DOIUrl":"https://doi.org/10.2174/2215083810666230914103404","url":null,"abstract":"Background and objectives: This study aimed to explore the treatment of thrombosis caused by Covid-19 with the drugs used in Unani medicine. Unani medicine has rich literature that mentions the pathogenesis, causes, and treatment of the diseases caused by obstruction of vessels. The study explores various drugs with actions that complement the resulting thrombolytic actions and details the rational treatment plan following the Unani medicine protocol. Methodology: The literature regarding thrombosis was surveyed from indexed online journals. The concept of thrombosis in Unani literature was surveyed from the source texts of Unani medicine. The treatment strategy and drugs with anti-thrombotic actions were explored, and a rational graded management of thrombosis in Covid-19 patients was presented that forms the general treatment plan of Unani medicine in patients with thrombosis. Results: The study observed that several Unani drugs from natural sources are mentioned for de-obstruent action. De-obstruent action is a composite action that encompasses anti-inflammatory, disintegratory, blood detoxification, and other activities. There was a concordance with the concept of thrombolytic action, as mentioned in conventional medicine. When rationally used, these drugs form a graded treatment of thrombosis associated with Covid-19. Conclusion: There is a potentially successful treatment plan with several de-obstruent drugs in Unani medicine that may be explored to treat thrombosis associated with Covid-19.","PeriodicalId":11026,"journal":{"name":"Current Traditional Medicine","volume":"31 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134970679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Urtica dioica (Stinging nettle): A Comprehensive & Concise Review on its Nutritional Profile and Therapeutic Applications","authors":"Namra Aziz, Yadav Rupali Vinod, Dhrubajyoti Sarkar, Ankita Wal, Vaibhav Verma, Pranay Wal","doi":"10.2174/2215083810666230912150053","DOIUrl":"https://doi.org/10.2174/2215083810666230912150053","url":null,"abstract":"Background: A relatively untapped origin of drugs is medicinal plants. Traditional medicine employs Urtica dioica L. to treat a variety of ailments. A plant that produces fresh leaves that are dehydrated and used as a powder or in various forms is gaining popularity as a recent source of very nutritious food. Objective: This review attempts to address its nutritional profile, as well as its bioactive chemical ingredients and known food functional activities, as well as its historical usage in food and medicine. To date, several bioactive chemical components from stinging nettle have been identified, including flavonoids, phenolic and amino acids, fatty acids and carotenoids. Method: A comprehensive analysis of the literature search was conducted. Several databases have been searched using the common terms Urtica dioica, stinging nettle, phenolic compounds and phytochemicals using Scopus, Science Direct, PubMed-Medline and Google Scholar as search engines. Conclusion: The therapeutic potential of Urtica dioica and its disease-preventing strategies are updated in this review article. Also, its classification, chemical composition, nutritive value, and pharmacological activities are enlisted in this review with further future perspectives of Urtica dioica.","PeriodicalId":11026,"journal":{"name":"Current Traditional Medicine","volume":"34 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135885457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring potentials of Electuaries for controlling Chronic Respiratory diseases in Unani medicine: a Systematic Review","authors":"Muzayyana Khan, Shaheen Akhlaq, Shariq Shamsi","doi":"10.2174/2215083810666230911141351","DOIUrl":"https://doi.org/10.2174/2215083810666230911141351","url":null,"abstract":"background: Chronic respiratory diseases rate has been increasing alarmingly, causing huge burden on the mortality and morbidity. Environmental pollution and occupational exposure, the major identified risk factors and endless adverse effects of conventional medicine put forward the need for better alternative options. Electuaries are the pharmaceutical formulation of poly herbal drugs that are employed as effective remedy for respiratory disorders in Unani system of medicine. objective: The aim is to assess the effectiveness of Unani pharmaco-therapeutics in the management of various respiratory diseases and the computation of drug/water and drug/sugar ratio for the elaborated electuaries. methods: A web-based review on certain selected Unani drugs and its molecular mechanism was carried out using the data bases such as Pub Med, Google Scholar, Science Direct and Scopus published until the end of June 2022. results: It was observed that several single drugs such as Khayarshambar (Cassia fistula L.), Sapistan (Cordia dichotama Forst), Asl-us- Soos (Glycyrrhiza glabra L.), Khatmi (Althea officianialis L.), Za’fran (Crocus sativus L.), Behīdāna (Cydonia oblonga Mill.) etc. used in Unani formulations claimed to be effective in management of respiratory diseases like COVID 19. The herbs and its chemical constituents showed the preventive effect on respiratory diseases with inflammatory cell mediators, lung pathologies, airway response and immunomodulatory effects. The results of research studies (preclinical, clinical or in silico) and their molecular mechanisms on Electuaries have proved to be optimal for the respiratory system. conclusion: Unani poly-pharmaceutics showed anti-inflammatory, anti-viral, anti-bacterial, anti-allergic, anti- tussive, mucolytic actions arresting respiratory diseases.","PeriodicalId":11026,"journal":{"name":"Current Traditional Medicine","volume":"18 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135981183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antihyperglycemic and Hypolipidemic Effect of Hydroalcoholic Extract of Dolichos lablab Linn in STZ induced Type 1 Diabetes Mellitus in Mice","authors":"Hari Kishan, Manjusha Choudhary, Sachin Sharma, Prabhjeet Kaur Bamrah, Nitesh Choudhary","doi":"10.2174/2215083810666230908155424","DOIUrl":"https://doi.org/10.2174/2215083810666230908155424","url":null,"abstract":"Background: Traditional herbs have been used in the human healthcare system as medicines, foods, or spices from ancient times. Dolichos lablab is an Indian medicinal herb with a good source of nutrition, and has insulin-like proteins, thus can be employed in the cure of diabetes. Objective: This study aims to evaluate the lipids and blood glucose lowering effect of Dolichos lablab hydroalcoholic extract by using STZ-induced type 1 diabetes mellitus in-vivo model. Methods: Animals were divided into five groups including vehicle control, diabetic control, extract treated (200 & 400 mg/kg), and standard group. All the treatment was continued for 14 days after the confirmation of diabetes. Food consumption, water intake, serum glucose, insulin, kidney function test, liver, and serum lipid profile were assessed to evaluate the antidiabetic potential of the plant. Results: Phytochemical analysis showed the presence of carbohydrates, alkaloids, flavonoids, protein, amino acids, and terpenoids. Extract treatment significantly diminished HbA1c, and blood glucose levels. In addition, an ameliorative effect on serum cholesterol, triglycerides, and lipoprotein was observed at 400 mg/kg/day dose. Moreover, blood urea nitrogen and hepatic SGPT were also reduced significantly with extract treatment. Conclusion: Therefore, the present study depicted that Dolichos lablab is a useful herb in diabetes management and possesses hypolipidemic potential.","PeriodicalId":11026,"journal":{"name":"Current Traditional Medicine","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136361818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Review on Pharmacological Potential of Medicago sativa Linn.","authors":"Rashmi Rani, Sumitra Nain, Survesh Kumar Paliwal","doi":"10.2174/2215083810666230907093431","DOIUrl":"https://doi.org/10.2174/2215083810666230907093431","url":null,"abstract":"Background: Medicago sativa Linn. in Hindi, is called lasunghas, and in English, it is called alfalfa. It is a well-known crop of the Fabaceae family. We can eat its sprouts as a salad vegetable. This plant has a wide range of uses as a feed crop and is tolerant to climate change. Objective: In this review, the authors discussed the active chemical constituents and pharmacological uses of Medicago sativa Linn. in various diseases. Methods: This review article gathered all the information after going through the research papers from different databases like Taylor & Francis, ResearchGate, Elsevier, PubMed, Wiley Online Library, and PMC. Results: Alfalfa has been shown to be an important origin of phytochemicals like amino acids, coumarins, alkaloids, carotenes, flavonoids, organic acids, digestive enzymes, phytosterols, saponins, phytoestrogens, phenolic compounds, polyamines, and a few other volatile organic compounds like ketones, terpenes, alcohols and furanoids. This plant is useful in CNS, anxiety, oxidative stress, hepatotoxicity, inflammation, cancer, atherosclerosis, diabetes, burn wounds, vitiligo, reproductive system, myocardial infraction, bacteria, xanthine oxidase and metabolic syndrome. Conclusion: This review may be helpful in knowing of Medicago sativa Linn. with greater therapeutic potential for treatment of various diseases.","PeriodicalId":11026,"journal":{"name":"Current Traditional Medicine","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135096565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Karnasphota: A neuroprotective herb from the treasure of Ayurveda","authors":"H.R. Topiya, D.J. Pandya","doi":"10.2174/2215083810666230905152757","DOIUrl":"https://doi.org/10.2174/2215083810666230905152757","url":null,"abstract":"ABSTRACT: The ancient science of life known as Ayurveda offers countless potential to uncover many unexplored manuscripts that lead to effective medications. Understanding traditional medicinal plants can open up a wealth of significant bioactive phytoconstituents with numerous significant pharmacological functions. This treasure must be located based on the understanding of old Ayurveda and other traditional references. Sapindaceae family member Cardiospermum halicacabum Linn. is a rich source of phytochemicals, including tannins, saponins, phenols, flavonoids, terpenoids, alkaloids, and sterols. Many of these phytochemicals exhibit antioxidant, anxiolytic, anti-inflammatory, anti-ulcer, anti-cancer, anti-microbial, antifungal, anti-bacterial, anti-diabetic, immunomodulatory, antiviral, cardioprotective, mainly neuroprotective properties according to Ayurveda. The plants' aerial parts are rich in phenolic acids, glycosidic compounds, tannins, and sterols. Researchers and academicians are examining the pharmacognosy, phytochemistry, and other pharmacological effects of the traditional medicinal plant known as Karnasphota (Cardiospermum halicacabum Linn.), which is cited in Ayurveda as one of the neuroprotective agents. Karnasphota (Cardiospermum halicacabum Linn.) is shown to have promising therapeutic potential by the scientific evidence offered by researchers and academics, and it can be further assessed as a novel candidate for drug discovery. The current review aims to examine the potential of the underexplored herb from Ayurveda \"Karnasphota\" for developing and designing future medications by reviewing the existence of medicinally significant secondary metabolites, potential pharmacological importance, and its role in neuroprotection in neurodegenerative diseases.","PeriodicalId":11026,"journal":{"name":"Current Traditional Medicine","volume":"32 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135363218","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ethnomedicinal uses, Pharmacological activity, and Analytical aspects of Galuteolin: A Natural Flavonoid of Medicinal Importance","authors":"D. Patel","doi":"10.2174/2215083810666230901115602","DOIUrl":"https://doi.org/10.2174/2215083810666230901115602","url":null,"abstract":"\u0000\u0000Nature is the best source of all raw materials that we need for growth, development, and better health. Flavonoids are an important class of phytochemicals found to be present in plants and their derived byproducts. Lonicera japonica and its active phytochemicals possess antiviral, anti-endotoxin, anti-pyretic, and blood fat-reducing properties in medicine. Moreover, Galuteolin is a natural flavonoid that has anti-oxidant, anti-tumor, anti-infective, and anti-inflammatory potential.\u0000\u0000\u0000\u0000In the present review article, we have collected all scientific information on galuteolin from different scientific databases and analyzed it to know the biological importance and therapeutic benefit of galuteolin in medicine against human disorders. Scientific data on galuteolin were collected from numerous literature databases, such as Google, Google Scholar, PubMed, Scopus and Science Direct. Detailed pharmacological data on galuteolin were collected from these scientific sources and analyzed in the present work to know the health-beneficial aspects of galuteolin in medicine. In addition, scientific data on analytical techniques of galuteolin were also collected and analyzed in the present work to know their importance in the separation, isolation, and identification of galuteolin in different plant materials.\u0000\u0000\u0000\u0000The present work signified the biological importance of galuteolin in medicine and other allied health sectors. Pharmacological data analysis revealed the health-beneficial aspects of galuteolin on rheumatoid arthritis, cerebral ischemia, carcinoma, COVID-19, Atherosclerosis, and melanin biosynthesis. Further, intestinal absorption and pharmacokinetic parameters of galuteolin were also discussed in the present work. Analytical data signified the importance of newer and modern analytical techniques in medicine for the qualitative and quantitative analysis of galuteolin in different biological samples.\u0000\u0000\u0000\u0000Scientific data analysis of galuteolin revealed its biological importance and therapeutic benefit in medicine.\u0000","PeriodicalId":11026,"journal":{"name":"Current Traditional Medicine","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48437455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"In vitro Study on Antioxidant and Antiglycation Activities, and Molecular Docking of Moroccan Medicinal Plants for Diabetes","authors":"Abdnim Rhizlan, Elbouzidi Amine, Hayat Ouassou, Amal Elrherabi, Ali Berraaouan, Abdelkhaleq Legssyer, A. Ziyyat, Hassane Mekhfi, M. Bnouham","doi":"10.2174/2215083810666230831154738","DOIUrl":"https://doi.org/10.2174/2215083810666230831154738","url":null,"abstract":"\u0000\u0000Moroccan medicinal plants with historical usage to treat diabetes have been analyzed to explore their potential anti-glycation and antioxidant activities through in vitro experiments. These investigations have been complemented by molecular docking.\u0000\u0000\u0000\u0000The present study has examined the in vitro antioxidant and antiglycation properties of six aqueous extracts from six medicinal plants (Ammodaucus leucotrichus, Thymelaea hirsuta, Arbutus unedo, Urtica dioica, Ptychotis verticillata, and Caralluma europaea), and two seeds oils from Argania spinosa and Opuntia dillenii. The antioxidant activity was determined by using the DPPH radical scavenging activity test and β-carotene/linoleic acid bleaching assay. In addition, the antiglycation activity was detected by using the hemoglobin protein model.\u0000\u0000\u0000\u0000All studied plant extracts have shown potent antioxidant and antiglycation activity. Furthermore, to confirm the in silico antiglycation activity of the selected medicinal plants, molecular docking techniques were used assuming that binding energy decreases as compound affinity increases; the best molecules responsible for the remarkable antiglycation activity have also been highlighted.\u0000\u0000\u0000\u0000Antidiabetic herbal medicines are responsible for the inhibition of oxidative activity and glycation. The molecular docking analysis showed catechin, kaempferol-O-acetylhexoside, luteolin, luteolin-7-O-glucoside, quercetin, and zeaxanthin, to have a high affinity to AGEs receptor and a potent inhibitory activity.\u0000","PeriodicalId":11026,"journal":{"name":"Current Traditional Medicine","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44938653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Viability of Superbrain Yoga Practise in Academic Setting: A Systematic Review","authors":"V. Vinu, J. Srikanth, Nagendra Prasad K, Lancy Dsouza","doi":"10.2174/2215083810666230830125242","DOIUrl":"https://doi.org/10.2174/2215083810666230830125242","url":null,"abstract":"\u0000\u0000Yoga has its roots in India's Vedic era. Practising it enhances the overall health and well-being of students. Superbrain yoga (SBY) is a brief exercise based on the principle of ear acupuncture and repetitive 14 squats. It is practised by many students in India and across other parts of the world.\u0000\u0000\u0000\u0000This systematic review assesses SBY on students' cognitive abilities, academic performance, as well as mental health benefits and discusses if using SBY in academic settings is viable.\u0000\u0000\u0000\u0000The intervention studies of SBY or mixed with other exercises practiced by the student population published in journals and indexed in Web of Science, SCOPUS, and PubMed, are taken into consideration for this review based on PRISMA guidelines. The primary keywords include Superbrain Yoga, Thoppukaranam, and Super Brain Yoga. Studies published in English peer-reviewed journals between 2005 to 2021 were considered.\u0000\u0000\u0000\u0000Fifteen studies met the inclusion criteria. The review found that SBY practise was feasible in academic settings, with advantages to students' cognitive state (memory, attention, concentration), academic performance, and mental health Additionally, SBY and other yogasana were proven to be beneficial in raising cognitive activity and promoting positive behavioural improvements in students with special needs.\u0000\u0000\u0000\u0000More rigorous trials on SBY are needed to substantiate the effectiveness.\u0000","PeriodicalId":11026,"journal":{"name":"Current Traditional Medicine","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43389944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}