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Nutrition Care Practices in Colorectal Cancer: A National Survey of Patients, Caregivers, and Healthcare Professionals in Canada. 结直肠癌的营养护理实践:加拿大对患者、护理人员和医疗保健专业人员的全国调查。
IF 3.6 4区 医学
Current oncology Pub Date : 2026-09-10 DOI: 10.3390/curroncol33090547
Iris M Karry, Sally S Chung, Barry D Stein, Olga Graifer, Katherine L Ford, R Thomas Jagoe, Marianne Fillion, Karmen More, Natasha Bassett-Saltarelli, Joseph Chon, Natalie Leon, Timothy R Asmis, Martin Chasen
{"title":"Nutrition Care Practices in Colorectal Cancer: A National Survey of Patients, Caregivers, and Healthcare Professionals in Canada.","authors":"Iris M Karry, Sally S Chung, Barry D Stein, Olga Graifer, Katherine L Ford, R Thomas Jagoe, Marianne Fillion, Karmen More, Natasha Bassett-Saltarelli, Joseph Chon, Natalie Leon, Timothy R Asmis, Martin Chasen","doi":"10.3390/curroncol33090547","DOIUrl":"10.3390/curroncol33090547","url":null,"abstract":"<p><p>Nutrition is an essential component of colorectal cancer (CRC) care, influencing treatment tolerance, functional status, and quality of life, yet it remains inconsistently integrated into practice. This study examined experiences with nutrition management and gaps in nutrition care among patients with CRC, caregivers, and healthcare professionals across Canada through a multi-center, cross-sectional survey conducted from July 2025 to February 2026. A total of 243 participants completed the survey, including 121 patients, 45 caregivers, and 77 healthcare professionals. Among patients, 51.2% reported that nutritional status was discussed or assessed during treatment, while 24.0% reported it was never discussed. More than half of patients (55.4%) said they did not receive adequate information regarding weight loss during treatment. Caregivers described substantial nutrition impact symptoms and identified a need for clearer guidance, emotional support, and improved access to dietitians. Healthcare professionals rated nutrition care as highly important yet reported barriers to effective delivery, including limited staffing, lack of standardized screening, and reactive care processes. Across groups, respondents emphasized the importance of timely, personalized, and culturally relevant nutrition care. Overall, nutrition remains insufficiently embedded in CRC care, highlighting the need for routine screening, standardized referral pathways, earlier intervention, and integrated patient-centered nutrition care models to improve CRC care.</p>","PeriodicalId":11012,"journal":{"name":"Current oncology","volume":"33 9","pages":""},"PeriodicalIF":3.6,"publicationDate":"2026-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13605743/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149036976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical Outcomes and New Treatments in Pediatric Brain Tumors. 儿童脑肿瘤的临床结果和新治疗方法。
IF 3.6 4区 医学
Current oncology Pub Date : 2026-09-10 DOI: 10.3390/curroncol33090549
Craig Erker, Sébastien Perreault
{"title":"Clinical Outcomes and New Treatments in Pediatric Brain Tumors.","authors":"Craig Erker, Sébastien Perreault","doi":"10.3390/curroncol33090549","DOIUrl":"10.3390/curroncol33090549","url":null,"abstract":"<p><p>Central nervous system (CNS) tumors represent the most common solid tumors of childhood and remain the leading cause of cancer-related mortality among pediatric patients [...].</p>","PeriodicalId":11012,"journal":{"name":"Current oncology","volume":"33 9","pages":""},"PeriodicalIF":3.6,"publicationDate":"2026-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13605487/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149036997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cell Therapy Transplant Canada (CTTC) Consensus-Based Review for the Use of Supportive Care and Topical Therapies for Chronic Graft-Versus-Host Disease. 加拿大细胞治疗移植(CTTC)基于共识的支持治疗和局部治疗慢性移植物抗宿主病的回顾。
IF 3.6 4区 医学
Current oncology Pub Date : 2026-09-10 DOI: 10.3390/curroncol33090548
Kylie Lepic, Joseph Aziz, Gizelle Popradi, Christopher Lemieux, Jennifer White, Stephanie Maier, Mohamed Elemary, Kirk Schultz, Kristjan Paulson, Ram Vasudevan Nampoothiri, David Allan, Dennis Dong Hwan Kim
{"title":"Cell Therapy Transplant Canada (CTTC) Consensus-Based Review for the Use of Supportive Care and Topical Therapies for Chronic Graft-Versus-Host Disease.","authors":"Kylie Lepic, Joseph Aziz, Gizelle Popradi, Christopher Lemieux, Jennifer White, Stephanie Maier, Mohamed Elemary, Kirk Schultz, Kristjan Paulson, Ram Vasudevan Nampoothiri, David Allan, Dennis Dong Hwan Kim","doi":"10.3390/curroncol33090548","DOIUrl":"10.3390/curroncol33090548","url":null,"abstract":"<p><p>This is a consensus-based Canadian review with the primary purpose of expanding knowledge regarding supportive and topical therapies for chronic graft vs. host disease (cGvHD). There is often a lack of confidence in treating certain organ specific manifestations, and access to specialists with organ specific expertise varies across the country. This paper covers information gained from a literature review and Canadian transplanter expertise and will serve as a guide for hematopoietic cell transplant healthcare providers to topical cGvHD therapies accessible in Canada. We will review common symptoms and signs focused specifically on skin, mouth, eye and genital tract cGvHD and on lifestyle modifications and topical treatments as an adjunct to our recent publication on systemic treatment for cGvHD.</p>","PeriodicalId":11012,"journal":{"name":"Current oncology","volume":"33 9","pages":""},"PeriodicalIF":3.6,"publicationDate":"2026-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13605794/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149036909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Beyond Chronological Age: A Scoping Review of Neurosurgical Intervention for Central Nervous System Tumors in the Very Elderly. 超越实足年龄:对高龄中枢神经系统肿瘤的神经外科干预的范围回顾。
IF 3.6 4区 医学
Current oncology Pub Date : 2026-09-10 DOI: 10.3390/curroncol33090550
Jacob Gould, Sarah Segal, Garin G Griffith, Saud K Zaidan, Saarang Patel, Arjit Singh, Hazem S Ghaith, Julian Gendreau
{"title":"Beyond Chronological Age: A Scoping Review of Neurosurgical Intervention for Central Nervous System Tumors in the Very Elderly.","authors":"Jacob Gould, Sarah Segal, Garin G Griffith, Saud K Zaidan, Saarang Patel, Arjit Singh, Hazem S Ghaith, Julian Gendreau","doi":"10.3390/curroncol33090550","DOIUrl":"10.3390/curroncol33090550","url":null,"abstract":"<p><p>Adults aged 75 years or older are increasingly considered for neurosurgical treatment of primary central nervous system tumors, yet the evidence guiding treatment selection remains fragmented. We conducted a scoping review of PubMed/MEDLINE, Ovid Embase, Scopus, and Web of Science from database inception through July 2026. Original clinical reports were eligible when they included separately extractable data for adults aged 75 years or older undergoing or being evaluated for tumor-directed neurosurgical intervention for primary intracranial, skull-base, cranial-nerve, spinal cord, meningeal, or primary vertebral tumors. Data were charted using a standardized framework and synthesized descriptively by tumor type, treatment intent, patient-selection factors, and reported outcomes. Eighty reports were included, of which 37 addressed glioma or glioblastoma and 25 addressed intracranial meningioma; 75 were retrospective. In glioma, greater resection was frequently associated with longer survival, although findings for subtotal resection were inconsistent and postoperative treatment completion was an important prognostic factor. In meningioma, functional preservation and independence were prominent considerations, while sellar, spinal, and vestibular schwannoma studies emphasized vision, neurologic function, and cranial-nerve outcomes. Quality of life, cognition, caregiver burden, and time at home were rarely reported. Surgical benefit in very elderly patients is tumor-specific, and future studies should prioritize prospective, patient-centered outcomes rather than relying primarily on survival or chronological age.</p>","PeriodicalId":11012,"journal":{"name":"Current oncology","volume":"33 9","pages":""},"PeriodicalIF":3.6,"publicationDate":"2026-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13605894/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149036846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical Value of an LDH-CA125-NLR Panel for Diagnosis, Platinum Resistance, and Prognostic Assessment in Epithelial Ovarian Cancer. LDH-CA125-NLR在上皮性卵巢癌诊断、铂耐药和预后评估中的临床价值
IF 3.6 4区 医学
Current oncology Pub Date : 2026-09-10 DOI: 10.3390/curroncol33090551
Shuiqing Xu, Jinzhen Guo, Ziyi Zhao, Yan Zhai, Yingying Liu, Hua Li
{"title":"Clinical Value of an LDH-CA125-NLR Panel for Diagnosis, Platinum Resistance, and Prognostic Assessment in Epithelial Ovarian Cancer.","authors":"Shuiqing Xu, Jinzhen Guo, Ziyi Zhao, Yan Zhai, Yingying Liu, Hua Li","doi":"10.3390/curroncol33090551","DOIUrl":"10.3390/curroncol33090551","url":null,"abstract":"<p><p>(1) Background/Objective: Routine blood tests may provide useful information at different stages of epithelial ovarian cancer (EOC) management. This study evaluated continuous lactate dehydrogenase (LDH), carbohydrate antigen 125 (CA125), and neutrophil-to-lymphocyte ratio (NLR) values for diagnostic discrimination in epithelial ovarian cancer (EOC) and, separately, triple-positive status in relation to platinum resistance and survival. (2) Methods: This retrospective study included 238 patients with EOC and 238 individually matched patients with benign ovarian lesions. Continuous biomarkers were entered into logistic regression models for diagnosis. Triple-positive status was defined as LDH > 195.5 U/L, CA125 > 35.37 U/mL, and NLR > 2.63. Logistic regression was used for platinum resistance and Cox regression for progression-free survival (PFS) and overall survival (OS). Bootstrap internal validation was performed for the diagnostic models and PFS nomogram. (3) Results: The continuous LDH + CA125 + NLR model yielded an AUC of 0.873, with 75.97% sensitivity and 88.66% specificity; AUCs were 0.751 in early-stage and 0.958 in advanced-stage EOC. Adding NLR to LDH + CA125 did not significantly improve the AUC overall or within stage groups. Triple-positive status was associated with platinum resistance (adjusted OR = 3.488, 95% CI 1.504-8.087; <i>p</i> = 0.004), shorter PFS (adjusted HR = 3.109, 95% CI 1.772-5.456; <i>p</i> < 0.001), and shorter OS in advanced-stage EOC (adjusted HR = 3.538, 95% CI 1.385-9.038; <i>p</i> = 0.008). The PFS nomogram had a bootstrap-corrected C-index of 0.7521. (4) Conclusions: The continuous three-marker model showed diagnostic discrimination in this selected surgical cohort, while triple-positive status was associated with platinum resistance and adverse survival outcomes. External validation is needed.</p>","PeriodicalId":11012,"journal":{"name":"Current oncology","volume":"33 9","pages":""},"PeriodicalIF":3.6,"publicationDate":"2026-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13605179/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149037019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessing Quality Gaps and Clinician Perspectives on AI Integration in Colorectal Cancer NGS Pathways. 评估人工智能在结直肠癌NGS通路中的质量差距和临床医生的观点。
IF 3.6 4区 医学
Current oncology Pub Date : 2026-09-09 DOI: 10.3390/curroncol33090540
Luxiga Thanabalachandran, Darya Ali, Avery Newman-Simmons, Claire Norman, Daniel Jafari, Tamara Grahovac, Aaron Pollett, Weei-Yuarn Huang, Lina Chen, Shaqil Kassam, Carly C Barron, Suneil Khanna, Kristin Wright, Stephanie Snow, Ron Burkes, Tao Wang, Andrea Grin, Taylor Moffat, Yuchen Li
{"title":"Assessing Quality Gaps and Clinician Perspectives on AI Integration in Colorectal Cancer NGS Pathways.","authors":"Luxiga Thanabalachandran, Darya Ali, Avery Newman-Simmons, Claire Norman, Daniel Jafari, Tamara Grahovac, Aaron Pollett, Weei-Yuarn Huang, Lina Chen, Shaqil Kassam, Carly C Barron, Suneil Khanna, Kristin Wright, Stephanie Snow, Ron Burkes, Tao Wang, Andrea Grin, Taylor Moffat, Yuchen Li","doi":"10.3390/curroncol33090540","DOIUrl":"10.3390/curroncol33090540","url":null,"abstract":"<p><p>Next-generation sequencing (NGS) is integral to colorectal cancer (CRC) care, but its value depends on results being available when treatment decisions are made. We conducted a qualitative study to identify quality gaps in CRC NGS pathways and assess perspectives on digital and artificial intelligence (AI)-enabled workflow support. Semi-structured interviews were conducted with 22 medical oncologists and pathologists from 14 Ontario hospitals, and transcripts were analyzed thematically. Five themes emerged: (1) clinical indications and test ordering, where initiation was inconsistent because of unclear reflex-testing criteria, reliance on upstream clinicians, staging uncertainty, evolving indications, and funding constraints; (2) tissue, pathology, and laboratory workflow, where participants attributed bottlenecks and turnaround variability to send-out testing, staffing, infrastructure, and capacity; (3) interdisciplinary communication and tracking, where informal communication, unclear ownership, and manual tracking highlighted the need for closed-loop confirmation and alerts; (4) reporting and clinical integration, where report clarity, interpretability, and timing affected use; and (5) electronic health record integration and AI integration, where fragmented systems and limited interoperability delayed result access. Participants supported clinician-supervised digital or AI-enabled tools for case identification, triage, tracking, and overdue-result alerts. CRC NGS optimization requires standardized reflex criteria, clearer ownership, closed-loop tracking, reliable routing, structured reporting, and interoperable infrastructure.</p>","PeriodicalId":11012,"journal":{"name":"Current oncology","volume":"33 9","pages":""},"PeriodicalIF":3.6,"publicationDate":"2026-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13605996/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149036913","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Idiopathic Pneumonia Syndrome and Pulmonary Toxicity After Total Body Irradiation for Bone Marrow Transplantation in the Modern Transplant Era. 现代移植时代骨髓移植全身照射后的特发性肺炎综合征和肺毒性。
IF 3.6 4区 医学
Current oncology Pub Date : 2026-09-09 DOI: 10.3390/curroncol33090545
Ruijia Jin, Justin Oh, Iman Baharmand, Matthew Chan, Jessica Chan, Andrea C Lo, Cassidy Northway, Conrad Yuen, I A Popescu, T P L Nghiem, Yasser Abou Mourad, Cheryl Duzenli
{"title":"Idiopathic Pneumonia Syndrome and Pulmonary Toxicity After Total Body Irradiation for Bone Marrow Transplantation in the Modern Transplant Era.","authors":"Ruijia Jin, Justin Oh, Iman Baharmand, Matthew Chan, Jessica Chan, Andrea C Lo, Cassidy Northway, Conrad Yuen, I A Popescu, T P L Nghiem, Yasser Abou Mourad, Cheryl Duzenli","doi":"10.3390/curroncol33090545","DOIUrl":"10.3390/curroncol33090545","url":null,"abstract":"<p><p>Total body irradiation (TBI) is commonly used for myeloablative conditioning prior to allogeneic hematopoietic stem cell transplantation (HSCT) in high-risk, relapsed, or refractory hematologic malignancies. Pulmonary toxicity (PT)-including pneumonia, diffuse alveolar hemorrhage, and interstitial pneumonitis-is a serious complication after HSCT. Idiopathic pneumonia syndrome (IPS), defined as widespread alveolar injury without cardiogenic or infectious causes, represents a non-infectious form of PT. This study characterizes PT and IPS and explores associated factors following TBI-based HSCT in adults. We conducted a retrospective review of a prospectively collected database of adult patients treated with TBI-based HSCT from 2015 to 2022. Clinical records and chest imaging were reviewed to identify PT and IPS. IPS occurred in 20 patients (18%) of the cohort, with 8 patients (7%) within 100 days and 13 patients (13%) after 100 days. One patient experienced both early- and late-onset IPS and was counted once in the cumulative analysis. Early pulmonary infection was associated with reduced overall survival in both univariable (<i>p</i> = 0.002) and multivariable 100-day landmark analyses (<i>p</i> = 0.047). Acute graft-versus-host disease (GVHD) was independently associated with improved survival (<i>p</i> = 0.017), whereas chronic GVHD was not statistically significant in the landmark analyses. PT and IPS incidences were consistent with previously published adult TBI cohorts. While no significant clinical or radiation-related predictors of IPS were identified, pulmonary infection emerged as a predictor of inferior overall survival.</p>","PeriodicalId":11012,"journal":{"name":"Current oncology","volume":"33 9","pages":""},"PeriodicalIF":3.6,"publicationDate":"2026-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13605090/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149037022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Investigating Quality of Life and Decision Regret in Patients Undergoing Laryngectomy. 调查喉切除术患者的生活质量和决策后悔。
IF 3.6 4区 医学
Current oncology Pub Date : 2026-09-09 DOI: 10.3390/curroncol33090541
Dagmawi Lulseged, Jedeiah Dickerson, Lauren Ottenstein, Margie Dixon, Rebecca Pentz, Nicole C Schmitt
{"title":"Investigating Quality of Life and Decision Regret in Patients Undergoing Laryngectomy.","authors":"Dagmawi Lulseged, Jedeiah Dickerson, Lauren Ottenstein, Margie Dixon, Rebecca Pentz, Nicole C Schmitt","doi":"10.3390/curroncol33090541","DOIUrl":"10.3390/curroncol33090541","url":null,"abstract":"<p><p>Total laryngectomy is a surgical procedure for advanced laryngeal cancer and can affect speech, swallowing, and breathing. This study compared the quality of life, swallowing function, and decision regret among patients who underwent primary total laryngectomy with adjuvant radiation (Group 1) versus salvage laryngectomy (Group 2). A survey was completed by 25 Group 1 patients and 27 Group 2 patients. Quality of life and swallowing ability were assessed using the University of Washington Quality of Life Questionnaire (UW-QOL) and M.D. Anderson Dysphagia Inventory (MDADI), while decision regret was measured using the Decision Regret Scale. Group 1 patients reported a higher mean total UW-QOL score (74.4) than Group 2 (68.2). Similarly, Group 1 patients demonstrated better swallowing outcomes, with a mean MDADI score of 70.28 compared to 63.90 in Group 2. Decision Regret scores were lower in Group 1 patients (31.4) than in Group 2 (35.37), indicating less regret regarding treatment decisions. However, all these differences did not reach statistical significance. Overall, these findings highlight the importance of fully informing patients of the impact of surgery on quality of life to assist them in their decision-making. Future studies can recruit larger cohorts and investigate the effectiveness of other laryngectomy treatments/procedures.</p>","PeriodicalId":11012,"journal":{"name":"Current oncology","volume":"33 9","pages":""},"PeriodicalIF":3.6,"publicationDate":"2026-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13605748/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149036954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
High-Grade Chondrosarcoma Involving the Xiphoid Process and Lower Sternum-The Continuing Role of Extended Open Chest Wall Surgery in the Era of Minimally Invasive Thoracic Surgery: A Case Report. 涉及剑突和胸骨下段的高级别软骨肉瘤——在微创胸外科时代扩展开放胸壁手术的持续作用:1例报告。
IF 3.6 4区 医学
Current oncology Pub Date : 2026-09-09 DOI: 10.3390/curroncol33090544
Thomas Rallis, Maria Mironidou-Tzouveleki, Vasileios Theocharidis, Apostolos Gogakos, Dimitrios Paliouras, Achilleas Lazopoulos, Nikolaos Christoglou, Panagiotis Panousis, Michael Katsamakas, Paraskevas Vrochidis, Meropi Koutourini, Myrto Tzinevi, Pipitsa Valsamaki, Alexandra Mpakosi, Nikolaos Barmpetakis
{"title":"High-Grade Chondrosarcoma Involving the Xiphoid Process and Lower Sternum-The Continuing Role of Extended Open Chest Wall Surgery in the Era of Minimally Invasive Thoracic Surgery: A Case Report.","authors":"Thomas Rallis, Maria Mironidou-Tzouveleki, Vasileios Theocharidis, Apostolos Gogakos, Dimitrios Paliouras, Achilleas Lazopoulos, Nikolaos Christoglou, Panagiotis Panousis, Michael Katsamakas, Paraskevas Vrochidis, Meropi Koutourini, Myrto Tzinevi, Pipitsa Valsamaki, Alexandra Mpakosi, Nikolaos Barmpetakis","doi":"10.3390/curroncol33090544","DOIUrl":"10.3390/curroncol33090544","url":null,"abstract":"<p><p>Primary chondrosarcoma of the sternum is a rare malignancy whose anatomical location can create major diagnostic, resection, and reconstruction challenges. We report a 62-year-old man with severe obesity and a heavy smoking history who presented with a progressively enlarging, painful sternal swelling. Preoperative imaging conducted via computed tomography and positron emission tomography-computed tomography demonstrated a large heterogeneous mass at the anterior thoracoabdominal junction infiltrating the xiphoid process. CT-guided biopsy established grade III chondrosarcoma. Because of the tumor's size, location, and infiltrative features, bilateral transverse thoraco-sternotomy (\"Clamshell\" Procedure) was performed. \"En bloc\" resection included the middle and lower sternum, involved soft tissues and adjacent costal arches, followed by prosthetic synthetic polypropylene mesh reconstruction. The final pathology documented tumor-free examined margins (R<sub>0</sub>), with an approximately 10 mm closest reported clearance. The postoperative course was prolonged and complex. The patient required 18 days of intensive care and tracheostomy on postoperative day 8 because of delayed awakening and intermittent oxygen desaturation. Wound dehiscence necessitated surgical revisions on postoperative days 29 and 44; during the second revision, the infected mesh was removed. The tracheostomy was removed on day 64, and the patient was discharged in a stable condition two days later. This case demonstrates that extensive open approaches remain indispensable for selected chest wall malignancies. It also emphasizes the importance of coordinated multidisciplinary perioperative care from diagnosis through recovery, while illustrating how reconstructive resources, patient risk, and infection can determine the procedure's outcome.</p>","PeriodicalId":11012,"journal":{"name":"Current oncology","volume":"33 9","pages":""},"PeriodicalIF":3.6,"publicationDate":"2026-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13605271/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149037032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
From Availability to Access: A Mixed-Methods Study of Digital Prostate Cancer Survivorship Support for Black Men. 从可得性到可及性:黑人男性前列腺癌存活支持的数字混合方法研究。
IF 3.6 4区 医学
Current oncology Pub Date : 2026-09-09 DOI: 10.3390/curroncol33090543
Olamide Okedara, Gabriela Ilie, Maren Brodovsky, Ross J Mason, Ricardo Rendon, Andrea Kokorovic, Greg Bailly, Howard Evans, Kunal Jana, Jasmir G Nayak, Ernest Chan, Stanley Flax, Nikhilesh Patil, David Bowes, Duvern Ramiah, Shingai Mutambirwa, Andrew Oberholzer, Lola Riley, Jordan Cole, William Carruthers, Sarah Taylar, Robert David Harold Rutledge
{"title":"From Availability to Access: A Mixed-Methods Study of Digital Prostate Cancer Survivorship Support for Black Men.","authors":"Olamide Okedara, Gabriela Ilie, Maren Brodovsky, Ross J Mason, Ricardo Rendon, Andrea Kokorovic, Greg Bailly, Howard Evans, Kunal Jana, Jasmir G Nayak, Ernest Chan, Stanley Flax, Nikhilesh Patil, David Bowes, Duvern Ramiah, Shingai Mutambirwa, Andrew Oberholzer, Lola Riley, Jordan Cole, William Carruthers, Sarah Taylar, Robert David Harold Rutledge","doi":"10.3390/curroncol33090543","DOIUrl":"10.3390/curroncol33090543","url":null,"abstract":"<p><p><b>Introduction:</b> Black men experience persistent disparities across the prostate cancer continuum, including inequities in access to survivorship support. This study examined the perceived value, acceptability, and experiences of accessing a multicomponent digital survivorship program among Black men with prostate cancer. <b>Methods:</b> This exploratory mixed-methods study was embedded within the ongoing international Phase 4 implementation trial of the Prostate Cancer Patient Empowerment Program (PC-PEP), a six-month digital intervention integrating exercise, pelvic floor muscle training, nutrition, stress management, psychosocial support, and peer connection. Fourteen self-identified Black participants contributed six-month program evaluation and qualitative data collected through open-ended responses and conference-based focus group discussions. Nine participants (64%) had undergone surgery with or without radiation and/or hormone therapy, four (29%) had received radiation with or without hormone therapy, and one (7%) was on active surveillance or had received no treatment. Quantitative data were summarized descriptively, and qualitative data were analyzed using inductive thematic analysis. <b>Results:</b> PC-PEP was highly valued, with median ratings of 10 (IQR 8-10) for likelihood of recommending the program and 9 (IQR 8-10) for overall usefulness. Among participants with available item-level data, 11/13 (85%) reported lifestyle improvement and 12/13 (92%) endorsed offering PC-PEP as standard care. Qualitative findings identified the value of holistic survivorship support, peer connection, normalization of vulnerability, and support for physical and psychological self-management. Participants also described limited awareness of PC-PEP at diagnosis and reliance on individual clinicians or incidental opportunities to learn about the program. Participants emphasized the need for earlier referral, greater representation, and culturally relevant community outreach. <b>Conclusions:</b> Black men who accessed PC-PEP reported high perceived value and identified benefits across multiple dimensions of survivorship. Their experiences, however, highlighted an important distinction between program availability and meaningful access: participants' experiences suggest that availability alone may not ensure timely connection to survivorship support. Earlier referral, culturally responsive outreach, and integration of survivorship support into routine prostate cancer care may help close this gap.</p>","PeriodicalId":11012,"journal":{"name":"Current oncology","volume":"33 9","pages":""},"PeriodicalIF":3.6,"publicationDate":"2026-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13605609/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149036924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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