Decis. Sci.Pub Date : 2021-08-06DOI: 10.20944/preprints202108.0152.v1
Summi Rai, Eliza A. Siwakoti, A. Kafle, H. P. Devkota, Ajaya Bhattarai
{"title":"Plant-Derived Saponins: A Review of Their Surfactant Properties and Applications","authors":"Summi Rai, Eliza A. Siwakoti, A. Kafle, H. P. Devkota, Ajaya Bhattarai","doi":"10.20944/preprints202108.0152.v1","DOIUrl":"https://doi.org/10.20944/preprints202108.0152.v1","url":null,"abstract":"Increasing environmental concern and consumer demand for natural, sustainable and eco-friendly products have prompted the replacement of synthetic surfactants with their natural plant-based alternatives. Saponins are the plant based natural surfactants characterized by their foam forming properties in aqueous solution. Their natural origin makes them eco-friendly, bio-degradable and non-toxic. Further, they possess better physicochemical properties than the syn-thetic ones. They are also reported to exhibit a lot of useful biological activities such as anti-cancer, antifungal, anti-inflammatory, antimicrobial, antioxidant and cholesterol-lowering properties. Because of their excellent surface activity, biological activities and wide distribution in nature, saponin rich plants deserve deeper insight as a sustainable source of natural surfactants as they possess the potential to replace toxic synthetic surfactants abundant today. This review article is intended to provide a brief overview on the saponins with a special notion on their surface-active properties. It encourages further studies on development of commercial formulations based on saponins for the complete replacement of the synthetic counter parts, making better use of plants sources thereby contributing to global agenda of green environment.","PeriodicalId":10987,"journal":{"name":"Decis. Sci.","volume":"14 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83388679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Decis. Sci.Pub Date : 2021-07-01DOI: 10.3390/sci3030033
A. Andrae
{"title":"Progress in Life Cycle Impact Assessment: Water Vapor Emissions and Respiratory Inorganics","authors":"A. Andrae","doi":"10.3390/sci3030033","DOIUrl":"https://doi.org/10.3390/sci3030033","url":null,"abstract":"Life cycle assessment (LCA) is being included formally in EcoDesign regulations. Especially product carbon footprint will be mandatory in Europe. However, life cycle impact assessment, including global warming potential (GWP) in LCA, is hampered by several challenges. One of these is a lack of water vapor characterization indexes for GWP. A life cycle inventory profile for air transport fuel, including water vapor emissions, is evaluated with state-of-the-art practice, i.e., Environmental Footprint (EF) Method and International Life Cycle Data (ILCD) 2011 Mid-point+, neglecting water vapor’s high altitude GWP compared to carbon dioxide. Then, the characterization factor in GWP over 100 years (GWP100) for water vapor and alternate normalization for particulates are introduced. The results are compared. The main findings are that the previous EF method and ILCD both generate rather realistic results for Particulate Matter and Respiratory Inorganics mid-point indicators, respectively, but the number of premature deaths should be better allocated to different specific emissions, and that water vapor may dominate the GWP100 result over the usual carbon dioxide. Respiratory inorganics may need one impact category, each starting with particles smaller than 2.5 µm. LCIA mid-points need measurable and understandable bases. The common knowledge of water vapor’s GWP100 should not be neglected in LCIA for air transport and beyond where relevant.","PeriodicalId":10987,"journal":{"name":"Decis. Sci.","volume":"27 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78553307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Decis. Sci.Pub Date : 2021-06-17DOI: 10.3390/SCI3030032
A. Auten, K. Cavey, J. Reed, F. Dolgener, T. Moriarty
{"title":"Effects of Transcranial Direct Current Stimulation on Cycling Time Trial Performance and Prefrontal Cortex Activation","authors":"A. Auten, K. Cavey, J. Reed, F. Dolgener, T. Moriarty","doi":"10.3390/SCI3030032","DOIUrl":"https://doi.org/10.3390/SCI3030032","url":null,"abstract":"Background: Transcranial direct current stimulation (tDCS) is a neuromodulatory technique that delivers low levels of a constant current via scalp electrodes to specifically targeted areas of the brain. The effects of tDCS on whole-body exercise performance has been of interest in recent literature. The purpose of the current investigation was to investigate if tDCS, administered via Halo Sport, influences time trial performance in trained cyclists, and if changes in exercise performance are associated with prefrontal cortex (PFC) activation and/or muscle oxygenation (SmO2). Methods: Twelve recreationally trained cyclists volunteered to participate in two 10-kilometer time trials following 20 minutes of tDCS or a sham condition. Results: T-tests showed there was no significant difference in performance (time to completion) or physiological measures (BLa-, HR, SmO2, PFC oxygenation) between the Halo and sham conditions. Conclusions: These results indicate that the application of tDCS via Halo Sport does not induce changes in exercise performance or related physiological parameters during a 10-kilometer cycling time trial.","PeriodicalId":10987,"journal":{"name":"Decis. Sci.","volume":"239 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73963234","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Decis. Sci.Pub Date : 2021-06-11DOI: 10.20944/PREPRINTS202106.0324.V1
Candi Citadini de Oliveira, R. F. Rupp, E. Ghisi
{"title":"Assessment of Air Quality Perception and Its Effects on Users’ Thermal Comfort in Office Buildings","authors":"Candi Citadini de Oliveira, R. F. Rupp, E. Ghisi","doi":"10.20944/PREPRINTS202106.0324.V1","DOIUrl":"https://doi.org/10.20944/PREPRINTS202106.0324.V1","url":null,"abstract":"Since people spend most of their time in indoor environments, the objective of this work was to study indoor air quality perception and its effects on users’ thermal comfort. Based on previous data from a building with a central air-conditioning system and two mixed-mode buildings located in the humid subtropical climate of Florianópolis, southern Brazil, statistical analyses were performed. Each user subjective answer obtained through a questionnaire was combined with the corresponding environmental conditions – measured using microclimate stations, a portable thermo-anemometer and a CO2 analyser. Results showed that improvement in air quality was associated with the reduction of air temperature and humidity ratio. Also, there was a significant influence of thermal, air movement and humidity sensation and acceptability of air quality perception. Users felt more satisfied or neutral with air quality for being in thermal comfort, and not because of the CO2 level – which means that air quality perception is influenced by factors other than CO2. This study recommends the implementation of an air exchange device in split air-conditioners with air recirculation used in mixed-mode buildings in Brazil. It is important to provide suitable indoor ventilation to reduce pollutants concentration, ensure good air quality and prevent respiratory diseases.","PeriodicalId":10987,"journal":{"name":"Decis. Sci.","volume":"103 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86270625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Decis. Sci.Pub Date : 2021-06-07DOI: 10.3390/SCI3020028
Ulla Timlin, Sofia Kauppila, Leneisja Jungsberg, T. Nordström, Kirsten Schmidt-Pedersen, H. Kyngäs, A. Rautio
{"title":"Perception of Health Challenges, Self-Rated Health and Feeling of Empowerment in a Changing Climate and Environment with Permafrost Thawing","authors":"Ulla Timlin, Sofia Kauppila, Leneisja Jungsberg, T. Nordström, Kirsten Schmidt-Pedersen, H. Kyngäs, A. Rautio","doi":"10.3390/SCI3020028","DOIUrl":"https://doi.org/10.3390/SCI3020028","url":null,"abstract":"Climate change is a global challenge which has direct and indirect health impacts on the lives of people and communities in the Arctic. The aim of our study was to evaluate the perception of permafrost thaw and health challenges and to determine which perceived environmental and adaptation factors relate to self-rated health and, more specifically, to feeling of empowerment when facing the changes and impacts of climate change and permafrost thawing. Questionnaire data (n = 100) were collected from one community located in Greenland, Disko Bay. Data were analyzed by cross-tabulation and the significances were tested either by Pearson’s χ2 test, Fisher’s exact test or by the t-test, when applicable. Based on these analyses, logistic and linear regression analyses were used to evaluate the associations between demographic variables, challenges posed by permafrost thaw and self-rated health, and associations between feeling of empowerment and perceived environmental/adaptation factors. The results indicated that climate change was not assessed as being a direct risk for the health of local people or their feeling of empowerment. Nature seemed to play an important role for local people, and not being in the natural environment for recreational activities seemed to decrease feeling of empowerment (OR 0.42, p = 0.042, 95% CI 0.17–0.97). This paper provides new, multidisciplinary research information about the perception of health challenges, health, and feeling of empowerment among people living in an environment impacted by permafrost thaw and climate change.","PeriodicalId":10987,"journal":{"name":"Decis. Sci.","volume":"56 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85977616","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Decis. Sci.Pub Date : 2021-06-02DOI: 10.3390/SCI3030031
M. Kfoury, C. Mouawad, M. Rifi, R. Sadek, J. Sabatier, H. Nehme, Z. Fajloun
{"title":"Montivipera bornmuelleri Venom: Inhibitory Effect on Staphylococcus epidermidis and Escherichia coli F1F0-ATPases and Cytotoxicity on HCT116 Cancer Cell Lines","authors":"M. Kfoury, C. Mouawad, M. Rifi, R. Sadek, J. Sabatier, H. Nehme, Z. Fajloun","doi":"10.3390/SCI3030031","DOIUrl":"https://doi.org/10.3390/SCI3030031","url":null,"abstract":"In this work, we pursued the biological characterization of the venom of Montivipera born-muelleri, a viper from the Lebanese mountains. In relativity to its antibacterial potential, the in-hibitory effect of this venom on the F1F0-ATPase enzymes of Gram-positive Staphylocoocus epider-midis and Gram-negative Escherichia coli bacteria was examined. In order to determine the de-gree of cytotoxicity of the venom on the HCT116 human colon cancer cell lines, the biological MTT proliferation and cell viability test were implemented. After validation of the enzymatic F1F0-ATPase model by the spectrophotometric method, using quercetin as the reference ligand, re-sults revealed that M. bornmuelleri venom is able to inhibit the activity of the enzyme of these two bacteria with a concentration of the order of 100-150 µg/mL. In addition, a venom concentration of 10 µg/mL was sufficient to kill the totality of HCT116 cell lines cultivated in vitro. These data show that M. bornmuelleri venom is a mixture of diverse molecules presenting activities of interest and is a potential source to explore in order to discover new drug candidates.","PeriodicalId":10987,"journal":{"name":"Decis. Sci.","volume":"27 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83195818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Decis. Sci.Pub Date : 2021-05-26DOI: 10.20944/PREPRINTS202105.0624.V1
Demetris Koutsoyiannis, P. Dimitriadis
{"title":"Towards Generic Simulation for Demanding Stochastic Processes","authors":"Demetris Koutsoyiannis, P. Dimitriadis","doi":"10.20944/PREPRINTS202105.0624.V1","DOIUrl":"https://doi.org/10.20944/PREPRINTS202105.0624.V1","url":null,"abstract":"We outline and test a new methodology for genuine simulation of stochastic processes with any dependence and any marginal distribution. We reproduce time dependence with a generalized, time symmetric or asymmetric, moving-average scheme. This implements linear filtering of non-Gaussian white noise, with the weights of the filter determined by analytical equations in terms of the autocovariance of the process. We approximate the marginal distribution of the process, irrespective of its type, using a number of its cumulants, which in turn determine the cumulants of white noise in a manner that can readily support the generation of random numbers from that approximation, so that it be applicable for stochastic simulation. The simulation method is genuine as it uses the process of interest directly without any transformation (e.g. normalization). We illustrate the method in a number of synthetic and real-world applications with either persistence or antipersistence, and with non-Gaussian marginal distributions that are bounded, thus making the problem more demanding. These include distributions bounded from both sides, such as uniform, and bounded form below, such as exponential and Pareto, possibly having a discontinuity at the origin (intermittence). All examples studied show the satisfactory performance of the method.","PeriodicalId":10987,"journal":{"name":"Decis. Sci.","volume":"33 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78832815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Decis. Sci.Pub Date : 2021-05-24DOI: 10.20944/PREPRINTS202105.0584.V1
Nikolaos Chalmpes, Georgios Asimakopoulos, M. Baikousi, A. Bourlinos, M. Karakassides, D. Gournis
{"title":"Hypergolic Synthesis of Inorganic Materials by the Reaction of Metallocene Dichlorides With Fuming Nitric Acid At Ambient Conditions: The Case of Photocatalytic Titania","authors":"Nikolaos Chalmpes, Georgios Asimakopoulos, M. Baikousi, A. Bourlinos, M. Karakassides, D. Gournis","doi":"10.20944/PREPRINTS202105.0584.V1","DOIUrl":"https://doi.org/10.20944/PREPRINTS202105.0584.V1","url":null,"abstract":"Hypergolic materials synthesis is a new preparative technique in materials science that allows a wide range of carbon or inorganic solids with useful properties to be obtained. Previously we have demonstrated that metallocenes are versatile reagents in the hypergolic synthesis of inorganic materials, such as γ-Fe2O3, Cr2O3, Co, Ni and alloy CoNi. Here, we take one step further by using metallocene dichlorides as precursors for the hypergolic synthesis of additional inorganic phases, such as photocatalytic titania. Metallocene dichlorides are closely related to metallocenes, thus expanding the arsenal of organometallic compounds that can be used in hypergolic materials synthesis. In the present case, we show that hypergolic ignition of the titanocene dichloride-fuming nitric acid pair results in the fast and spontaneous formation of titania nanoparticles at ambient conditions in the form of anatase-rutile mixed phases. The obtained titania shows good photocatalytic activity towards Cr(VI) removal (100 % within 9 h), the latter being dramatically enhanced after calcination of the powder at 500 °C (100 % within 3 h). Worth noting, this performance was found to be comparable to that of commercially available P25 TiO2 under identical conditions. The cases of zirconocene, hafnocene and molybdocene dichlorides are complementary discussed in this work, aiming to show the wider applicability of metallocene dichlorides in the hypergolic synthesis of inorganic materials (ZrO2, HfO2, MoO2).","PeriodicalId":10987,"journal":{"name":"Decis. Sci.","volume":"189 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77366925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Decis. Sci.Pub Date : 2021-05-19DOI: 10.20944/PREPRINTS202105.0450.V1
E. Fröhlich
{"title":"Replacement Strategies for Animal Studies in Inhalation Testing","authors":"E. Fröhlich","doi":"10.20944/PREPRINTS202105.0450.V1","DOIUrl":"https://doi.org/10.20944/PREPRINTS202105.0450.V1","url":null,"abstract":"Testing in animals is mandatory in drug testing and the gold standard for evaluation of toxicity. This situation is expected to change in the future because the 3Rs principle, which stands for replacement, reduction and refinement of the use of animals in science, is reinforced by many countries. On the other hand, technologies for alternatives to animals experiments have increased. The necessity to develop and use of alternatives is influenced by the complexity of the research topic and also by the fact, to which extent the currently used animal models can mimic human physiology and/or exposure. Rodent lung morphology and physiology differs markedly for that of humans and inhalation exposure of the animals are challenging. In vitro and in silico methods can assess important aspects of the in vivo action, namely particle deposition, dissolution, action at and permeation across the respiratory barrier and pharmacokinetics. Out of the numerous homemade in vitro and in silico models some are available commercially or open access. This review discusses limitations of animal models and exposure systems and proposes a panel of in vitro and in silico techniques that, in the future, may replace animal experimentation in inhalation testing.","PeriodicalId":10987,"journal":{"name":"Decis. Sci.","volume":"43 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86695287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Decis. Sci.Pub Date : 2021-05-12DOI: 10.3390/SCI3020025
J. Patrick, Philip Q. Yang
{"title":"Health Insurance Coverage before and after the Affordable Care Act in the USA","authors":"J. Patrick, Philip Q. Yang","doi":"10.3390/SCI3020025","DOIUrl":"https://doi.org/10.3390/SCI3020025","url":null,"abstract":"The Affordable Care Act (ACA) is at the crossroads. It is important to evaluate the effectiveness of the ACA in order to make rational decisions about the ongoing healthcare reform, but existing research into its effect on health insurance status in the United States is insufficient and descriptive. Using data from the National Health Interview Surveys from 2009 to 2015, this study examines changes in health insurance status and its determinants before the ACA in 2009, during its partial implementation in 2010–2013, and after its full implementation in 2014 and 2015. The results of trend analysis indicate a significant increase in national health insurance rate from 82.2% in 2009 to 89.4% in 2015. Logistic regression analyses confirm the similar impact of age, gender, race, marital status, nativity, citizenship, education, and poverty on health insurance status before and after the ACA. Despite similar effects across years, controlling for other variables, youth aged 26 or below, the foreign-born, Asians, and other races had a greater probability of gaining health insurance after the ACA than before the ACA; however, the odds of obtaining health insurance for Hispanics and the impoverished rose slightly during the partial implementation of the ACA, but somewhat declined after the full implementation of the ACA starting in 2014. These findings should be taken into account by the U.S. Government in deciding the fate of the ACA.","PeriodicalId":10987,"journal":{"name":"Decis. Sci.","volume":"5 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82925938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}