Current opinion in pediatrics最新文献_第9页

Updates on postinfectious skin rashes in pediatric dermatology. 儿科皮肤科感染后皮疹的最新进展。

IF 2.2 3区医学

Current opinion in pediatrics Pub Date : 2024-08-01 Epub Date: 2024-06-05 DOI: 10.1097/MOP.0000000000001376

Samantha Shwe Daniel, Caitlin Peterman, Smita Awasthi

{"title":"Updates on postinfectious skin rashes in pediatric dermatology.","authors":"Samantha Shwe Daniel, Caitlin Peterman, Smita Awasthi","doi":"10.1097/MOP.0000000000001376","DOIUrl":"10.1097/MOP.0000000000001376","url":null,"abstract":"Purpose of review: This review provides updates on postinfectious skin rashes in the pediatric population from recently published literature.Recent findings: The COVID-19 pandemic and its sequelae remain a focus of research on pediatric infectious skin rashes. Multisystem inflammatory syndrome in children (MIS-C) and reactive infectious mucocutaneous eruption (RIME) are common complications of infection with SARS-COV-2 in the pediatric population. Most cases of MIS-C show low mortality and suggest mucocutaneous symptoms do not correlate with COVID-19 disease severity. Cases of papular acrodermatitis of childhood, also known as Gianotti-Crosti, have also been reported in association with SARS-COV-2, and can present similarly in reaction to other viral infection like molluscum contagiosum, known as a Gianotti-Crosti syndrome-like reaction (GCLR). Other relevant studies on postinfectious skin rashes include updates on the management of staphylococcal scalded skin syndrome (SSSS), with newer evidence advocating for beta-lactam monotherapy without clindamycin and reduced ancillary testing. Finally, the emergence of antifungal resistance due to Trichophyton indotinae is a growing global health concern emphasizing the need for improved antifungal stewardship.Summary: It is prudent for clinicians to be informed of both common and rare diagnoses that have emerged more recently in association with the COVID-19 pandemic, in addition to other diseases with newer evidence-based recommendations to guide management.","PeriodicalId":10985,"journal":{"name":"Current opinion in pediatrics","volume":"36 4","pages":"431-435"},"PeriodicalIF":2.2,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141491234","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Noninfectious causes of alopecia in the pediatric population. 儿童脱发的非感染性原因。

IF 2.2 3区医学

Current opinion in pediatrics Pub Date : 2024-08-01 Epub Date: 2024-05-29 DOI: 10.1097/MOP.0000000000001374

Elie Saliba, Asghar Shah, Samer Wahood, Remie Chrabieh

引用次数: 0

Strategies to minimize procedure-related pain and anxiety: lessons from pediatric dermatology. 尽量减少手术相关疼痛和焦虑的策略：从儿科皮肤病学中汲取的经验。

IF 2.2 3区医学

Current opinion in pediatrics Pub Date : 2024-08-01 Epub Date: 2024-06-05 DOI: 10.1097/MOP.0000000000001371

Nadine Abouchaleh, Cheryl Bayart

引用次数: 0

Update on the use of long-acting growth hormone in children. 儿童使用长效生长激素的最新情况。

IF 2.2 3区医学

Current opinion in pediatrics Pub Date : 2024-08-01 Epub Date: 2024-05-07 DOI: 10.1097/MOP.0000000000001362

Margaret Cristina da Silva Boguszewski, Cesar Luiz Boguszewski

{"title":"Update on the use of long-acting growth hormone in children.","authors":"Margaret Cristina da Silva Boguszewski, Cesar Luiz Boguszewski","doi":"10.1097/MOP.0000000000001362","DOIUrl":"10.1097/MOP.0000000000001362","url":null,"abstract":"Purpose of review: After extensive research and many years of waiting, long-acting growth hormone (LAGH) formulations have finally become a reality in clinical practice and emerge as a potential solution to address the challenges of daily injections of recombinant human GH (rhGH). In this review, we present a brief history of the development of LAGH and provide a critical analysis of the existing literature on the five LAGH available and approved to date for treatment in children.Recent findings: In clinical trials, LAGH therapy has shown noninferiority compared with daily rhGH therapy in promoting linear growth in children with GH deficiency, with similar rates of adverse events.Summary: In the real world, many questions still need to be answered, such as whether a specific group of patients will benefit most from the weekly injection, whether compliance will be better compared with daily rhGH, whether long-term efficacy, monitoring and safety profile will be the same for the different LAGH compounds, and whether the cost-effectiveness will justify their use in different settings.","PeriodicalId":10985,"journal":{"name":"Current opinion in pediatrics","volume":" ","pages":"437-441"},"PeriodicalIF":2.2,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140921188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Editorial. 社论

IF 2.2 3区医学

Current opinion in pediatrics Pub Date : 2024-08-01 Epub Date: 2024-07-04 DOI: 10.1097/MOP.0000000000001373

Sally Radovick

引用次数: 0

"Minimally symptomatic" congenital cytomegalovirus infection: latest data and emerging concepts. "症状轻微 "的先天性巨细胞病毒感染：最新数据和新概念。

IF 2.2 3区医学

Current opinion in pediatrics Pub Date : 2024-08-01 Epub Date: 2024-05-14 DOI: 10.1097/MOP.0000000000001364

Ashley Howard, Javier K Nishikawa, Pablo J Sánchez

{"title":"\"Minimally symptomatic\" congenital cytomegalovirus infection: latest data and emerging concepts.","authors":"Ashley Howard, Javier K Nishikawa, Pablo J Sánchez","doi":"10.1097/MOP.0000000000001364","DOIUrl":"10.1097/MOP.0000000000001364","url":null,"abstract":"Purpose of review: Universal and targeted screening of newborns for congenital cytomegalovirus (CMV) infection is increasing globally. Questions remain concerning the management of infants who have been identified with congenital CMV infection, especially those with \"minimally symptomatic\" or clinically inapparent infection. Our objective is to discuss current management of CMV-infected neonates with a focus on less affected infants with or without sensorineural hearing loss (SNHL).Recent findings: Valganciclovir is being prescribed increasingly in neonates with congenital CMV infection for improvement in hearing outcomes through 2 years of age. Treatment initiated in the first month of age is recommended for clinically apparent disease. A recent study showed hearing improvement at 18-22 months of age when therapy was initiated at age 1-3 months in infants with clinically inapparent CMV infection and isolated SNHL.Summary: Antiviral therapy with either ganciclovir or valganciclovir has shown moderate benefit in prevention of hearing deterioration among infants with clinically apparent CMV infection or isolated SNHL. Sustainability of benefit beyond 2 years of age remains unknown. At present, infants with clinically inapparent CMV infection (normal complete evaluation including hearing) should not receive antiviral therapy. All CMV-infected infants require close audiological and neurodevelopmental follow-up.","PeriodicalId":10985,"journal":{"name":"Current opinion in pediatrics","volume":" ","pages":"480-488"},"PeriodicalIF":2.2,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140920773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Heightism, growth hormone treatment, and social functioning: a holistic approach to a persistent clinical challenge. 身高不足症、生长激素治疗和社会功能：以综合方法应对长期存在的临床难题。

IF 2.2 3区医学

Current opinion in pediatrics Pub Date : 2024-08-01 Epub Date: 2024-05-10 DOI: 10.1097/MOP.0000000000001363

Camilia Kamoun, Emily A Largent, Adda Grimberg

{"title":"Heightism, growth hormone treatment, and social functioning: a holistic approach to a persistent clinical challenge.","authors":"Camilia Kamoun, Emily A Largent, Adda Grimberg","doi":"10.1097/MOP.0000000000001363","DOIUrl":"10.1097/MOP.0000000000001363","url":null,"abstract":"Purpose of review: Use of recombinant human growth hormone (rhGH) treatment to increase height in children with non-growth hormone deficient short stature is becoming more common. Yet, the evidence to support the notion that augmenting height directly leads to increased well being, specifically psychosocial well being, is inconsistent, with high-quality evidence lacking.Recent findings: Review of recent studies demonstrates that the association between height augmentation and psychosocial well being is complex. The direct contribution of height to well being may be less than the current model of clinical care of short stature assumes. Rather, the new studies provide evidence to support a role for psychosocial factors, including height-related beliefs, social support, and coping skills, in promoting psychosocial well being, specifically quality of life and self-esteem.Summary: Clinical care of short stature would benefit from incorporating a holistic model of care that considers psychosocial interventions in addition to, or instead of, rhGH treatment.","PeriodicalId":10985,"journal":{"name":"Current opinion in pediatrics","volume":" ","pages":"442-448"},"PeriodicalIF":2.2,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140920933","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prenatal and postnatal evaluation of differences of sex development: a user's guide for clinicians and families. 产前和产后性别发育差异评估：临床医生和家庭用户指南》。

IF 3.6 3区医学

Current opinion in pediatrics Pub Date : 2024-07-31 DOI: 10.1097/mop.0000000000001388

Erica M Weidler,Brielle Ochoa,Kathleen van Leeuwen

{"title":"Prenatal and postnatal evaluation of differences of sex development: a user's guide for clinicians and families.","authors":"Erica M Weidler,Brielle Ochoa,Kathleen van Leeuwen","doi":"10.1097/mop.0000000000001388","DOIUrl":"https://doi.org/10.1097/mop.0000000000001388","url":null,"abstract":"PURPOSE OF REVIEWDifferences of sex development (DSD) are a group of chromosomal, gonadal, and anatomic conditions that are not often diagnosed during pregnancy. Families and clinicians need diagnostic guidance that supports all aspects of the care from the prenatal to postnatal period.RECENT FINDINGSNoninvasive prenatal screening (NIPS) is obtained by sampling cell-free fetal DNA in the mother's bloodstream in the first trimester. While its primary purpose is to screen for genetic aneuploidies, it is also used to determine the sex of the fetus. When screening ultrasound shows genital anatomy that is discordant with the sex determination by NIPS, a DSD workup is warranted. The use of this relatively new screening tool may result in a higher number of prenatal referrals than in the past.SUMMARYThis review summarizes suggested prenatal counseling, neonatal management, and postnatal workup of the most common DSD diagnoses. All of these diagnoses are rare, but the common features that families face are addressed with particular emphasis on psychosocial support and a measured shared decision-making approach.","PeriodicalId":10985,"journal":{"name":"Current opinion in pediatrics","volume":"75 1","pages":"547-553"},"PeriodicalIF":3.6,"publicationDate":"2024-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142191110","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Diastolic dysfunction: assessment and implications on the single ventricle circulation. 舒张功能障碍：评估和对单心室循环的影响。

IF 3.6 3区医学

Current opinion in pediatrics Pub Date : 2024-07-24 DOI: 10.1097/mop.0000000000001385

Ahmed A Hassan,Alexander Van De Bruaene,Mark K Friedberg

{"title":"Diastolic dysfunction: assessment and implications on the single ventricle circulation.","authors":"Ahmed A Hassan,Alexander Van De Bruaene,Mark K Friedberg","doi":"10.1097/mop.0000000000001385","DOIUrl":"https://doi.org/10.1097/mop.0000000000001385","url":null,"abstract":"PURPOSE OF REVIEWPatients with a functionally single ventricle (SV) are palliated with a series of procedures leading to a Fontan circulation. Over the life span, a substantial proportion of SV patients develop heart failure that can arise from circulatory or ventricular failure. Diastolic dysfunction (DD) is an important determinant of adverse outcomes in SV patients. However, assessment and categorization of DD in the SV remains elusive. We review recent literature and developments in assessment of DD in the SV and its relation to clinical outcomes.RECENT FINDINGSDD is prevalent in the SV and associated with worse outcomes. Occult DD can be exposed with provocative testing by exercise or preload challenge during catheterization. Likewise, sensitivity to detect DD may be increased via assessment of atrial function and strain imaging. Recent studies revisiting previous concepts such as incoordinate diastolic wall motion show that these are associated with SV end-diastolic pressures and post-Fontan recovery, yielding accessible DD assessment. Emerging technologies such as ultrafast ultrasound (UFUS) can provide noninvasive assessment of myocardial stiffness, inefficient diastolic flow patterns and intraventricular pressure gradients, thereby yielding new tools and insights into diastolic myocardial and hemodynamic properties.SUMMARYCharacterizing DD in the SV continues to have substantial limitations, necessitating synthesis of multiple parameters into an overall assessment, accounting for their change over time, and in the context of the patient's clinical status. New and emerging techniques may help advance DD assessment and the ability to track response to treatment of new targets.","PeriodicalId":10985,"journal":{"name":"Current opinion in pediatrics","volume":"20 1","pages":"503-511"},"PeriodicalIF":3.6,"publicationDate":"2024-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142191109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Acute rheumatic fever and rheumatic heart disease: updates in diagnosis and treatment. 急性风湿热和风湿性心脏病：诊断和治疗的最新进展。

IF 3.6 3区医学

Current opinion in pediatrics Pub Date : 2024-07-22 DOI: 10.1097/mop.0000000000001384

Joselyn Rwebembera,Andrea Beaton

{"title":"Acute rheumatic fever and rheumatic heart disease: updates in diagnosis and treatment.","authors":"Joselyn Rwebembera,Andrea Beaton","doi":"10.1097/mop.0000000000001384","DOIUrl":"https://doi.org/10.1097/mop.0000000000001384","url":null,"abstract":"PURPOSE OF REVIEWTo summarize the latest developments in rheumatic fever and rheumatic heart disease (RHD) prevention, (early) diagnosis, and treatment.RECENT FINDINGSThe revised Jones criteria have demonstrated increased sensitivity and specificity for rheumatic fever diagnosis in high-risk populations. The management of rheumatic fever remains symptom-based, with no treatment options proven to alter the disease course or prevent chronic RHD. The revised World Heart Federation (WHF) guidelines for the echocardiographic diagnosis of RHD encourage task-shifting of RHD screening, extending reach in endemic regions. These guidelines also present an A-D classification of RHD and provide recommendations for the management of early disease. Integrated models for RHD screening within existing health structures are emerging and automated intelligence is showing potential to support RHD screening and diagnosis. Innovative strategies to foster adherence and equitable access to secondary prophylaxis, such as re-examination of the efficacy of oral penicillin, trials of longer acting penicillin formulations and implants are underway. There is renewed interest and investment in a well tolerated and effective GAS vaccine.SUMMARYWe are living in a time of possibility with global acceleration to address the prevailing burden of RHD. Together, we can ensure that RHD does not once again fall off the global health agenda, until equitable elimination has been achieved.","PeriodicalId":10985,"journal":{"name":"Current opinion in pediatrics","volume":"37 1","pages":"496-502"},"PeriodicalIF":3.6,"publicationDate":"2024-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142191111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0