Current Opinion in Allergy and Clinical Immunology最新文献

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Novel therapeutic receptor agonists and antagonists in allergic conjunctivitis. 过敏性结膜炎的新型治疗受体激动剂和拮抗剂。
IF 3 4区 医学
Current Opinion in Allergy and Clinical Immunology Pub Date : 2024-10-01 Epub Date: 2024-07-22 DOI: 10.1097/ACI.0000000000001010
Sampson L Abu, Navpreet K Hehar, DeGaulle I Chigbu
{"title":"Novel therapeutic receptor agonists and antagonists in allergic conjunctivitis.","authors":"Sampson L Abu, Navpreet K Hehar, DeGaulle I Chigbu","doi":"10.1097/ACI.0000000000001010","DOIUrl":"10.1097/ACI.0000000000001010","url":null,"abstract":"<p><strong>Purpose of review: </strong>Allergic conjunctivitis is characterized by the development of pathophysiological changes to the ocular surface, which occurs when pro-allergic and pro-inflammatory mediators interact with their cognate receptors expressed on immune and nonimmune cells. Traditional treatments with antihistamines and corticosteroids provide relief, but there is a need for more efficacious and tolerable long-term therapy with a better safety profile. This article aims to provide an overview of the mode of action and clinical application of agonist therapies targeting glucocorticoid, melanocortin, and toll-like receptors, as well as antagonist therapies targeting cytokine, chemokine, integrin, and histamine receptors.</p><p><strong>Recent findings: </strong>There has been considerable advancement in immunology and pharmacology, as well as a greater understanding of the cellular and molecular mechanisms of allergic conjunctivitis. Recent research advancing therapy for allergic conjunctivitis has focused on developing synthetic molecules and biologics that can interfere with the process of the allergic immune reaction.</p><p><strong>Summary: </strong>This review discusses novel therapeutic receptors being explored agonistically or antagonistically to develop alternative treatment options for allergic conjunctivitis. These novel approaches hold promise for improving the management of allergic eye diseases, offering patients hope for more effective and safer treatment options in the future.</p>","PeriodicalId":10956,"journal":{"name":"Current Opinion in Allergy and Clinical Immunology","volume":null,"pages":null},"PeriodicalIF":3.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141855046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evidence-based data support strategies for the prevention of Hymenoptera venom anaphylaxis. 基于证据的数据支持预防膜翅目昆虫毒液过敏性休克的策略。
IF 3 4区 医学
Current Opinion in Allergy and Clinical Immunology Pub Date : 2024-10-01 Epub Date: 2024-07-22 DOI: 10.1097/ACI.0000000000001011
Audrey Kamga, Jean Luc Bourrain, Pascal Demoly, Luciana Kase Tanno
{"title":"Evidence-based data support strategies for the prevention of Hymenoptera venom anaphylaxis.","authors":"Audrey Kamga, Jean Luc Bourrain, Pascal Demoly, Luciana Kase Tanno","doi":"10.1097/ACI.0000000000001011","DOIUrl":"10.1097/ACI.0000000000001011","url":null,"abstract":"<p><strong>Purpose of review: </strong>This review aims to identify phenotypes at-risk of Hymenoptera venom-induced anaphylaxis (HVA), focusing on different perspectives (epidemiological, clinical, and therapeutic) in order to adapt future preventive strategies.</p><p><strong>Recent findings: </strong>HVA remains one of the leading causes of anaphylaxis, with a broad pattern of symptoms. Although most cases occur outside healthcare settings, data indicate a high emergency admission rate due to insect stings. Mortality is often underestimated because of the lack of witnesses and difficulties in recognizing the signs and the culprit. Targeting risk factors could be a clue to improve these statistics and the prognosis of the disease.Potential risk factors for severe HVA in the European population are basal serum tryptase (BST) above 8 μg, mast cell disorders, the absence of skin symptoms, and cardiovascular conditions requiring the use of beta blockers and ACE inhibitors. Identifying these criteria, mainly based on clinical patterns, helps to develop personalized strategies for management and prevention.</p><p><strong>Summary: </strong>With a personalized medicine approach, phenotypes must be characterized to adapt to the management of patients suffering from Hymenoptera venom anaphylaxis (HVA), including venom immunotherapy (VIT). In this systematic review, all articles mentioned systemic reactions with heterogeneous severity degrees. Half of those reported grade III-IV systemic reactions (Ring and Messmer). HVA clinical patterns could be worsened by one Hymenoptera sting, a patient's history with mast cell disorders, or cardiovascular diseases. VIT failure was attributed to bee venom extract and monotherapy in two-thirds of publications. Findings stress the difficulty of having uniform epidemiological data on HVA and the lack of financial support in some world regions to support appropriate management of these conditions. Although observing a heterogeneity of data, we were able to identify potential risk factors, in particular for the severe cases. We believe our work will support allergists and health professionals to implement improved personalized management of patients suffering from severe HVA.</p>","PeriodicalId":10956,"journal":{"name":"Current Opinion in Allergy and Clinical Immunology","volume":null,"pages":null},"PeriodicalIF":3.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141757632","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Integrative therapeutics for ocular surface disorders. 眼表疾病的综合疗法。
IF 3 4区 医学
Current Opinion in Allergy and Clinical Immunology Pub Date : 2024-10-01 Epub Date: 2024-08-13 DOI: 10.1097/ACI.0000000000001024
Atoosa Kourosh, Anil Nanda, Dipa K Sheth, Fariba Eshraghi Parmer
{"title":"Integrative therapeutics for ocular surface disorders.","authors":"Atoosa Kourosh, Anil Nanda, Dipa K Sheth, Fariba Eshraghi Parmer","doi":"10.1097/ACI.0000000000001024","DOIUrl":"10.1097/ACI.0000000000001024","url":null,"abstract":"<p><strong>Purpose of review: </strong>Integrative medicine techniques are increasingly accepted into the treatment paradigm for many chronic disorders including eye disease. Over 71% of patients, including 67% of those with eye disorders, use some form of Integrative therapy. Physicians should be well versed in evidence-based therapies to know how to refer patients for the best complimentary care. We highlight the most effective integrative therapeutics from different complementary treatment paradigms to offer a framework for approaching therapy in patients with ocular surface disorders (OSDs).</p><p><strong>Recent findings: </strong>Lifestyle and behavioral modifications help a proportion of people with OSDs like dry eye disease and allergic conjunctivitis, which are interrelated disorders. Nutrition and supplementation can also play a role in addressing underlying inflammation and improving OSD symptoms. Acupuncture and traditional herbal medicine may also benefit some patients. New technologies offer innovative treatment pathways in the treatment of OSD but require referral to Ocular Surface Treatment Centers.</p><p><strong>Summary: </strong>Integrative treatment approach for OSD incorporates allopathic medicine, traditional remedies and lifestyle behavioral interventions, Ayurveda and herbal medicine, Nutritional Supplements, Homeopathy, Acupuncture and Chinese Medicine. New cutting-edge technologies offer breakthroughs in difficult to treat ocular surface cases. Collaboration between allergy or otolaryngology offices, complementary practitioners, as well as optometrists and ophthalmologists in Ocular Surface Treatment Centers can offer patients new avenues of treatment.</p>","PeriodicalId":10956,"journal":{"name":"Current Opinion in Allergy and Clinical Immunology","volume":null,"pages":null},"PeriodicalIF":3.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141975259","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Artificial intelligence and machine learning for anaphylaxis algorithms. 用于过敏性休克算法的人工智能和机器学习。
IF 3 4区 医学
Current Opinion in Allergy and Clinical Immunology Pub Date : 2024-10-01 Epub Date: 2024-07-24 DOI: 10.1097/ACI.0000000000001015
Christopher Miller, Michelle Manious, Jay Portnoy
{"title":"Artificial intelligence and machine learning for anaphylaxis algorithms.","authors":"Christopher Miller, Michelle Manious, Jay Portnoy","doi":"10.1097/ACI.0000000000001015","DOIUrl":"10.1097/ACI.0000000000001015","url":null,"abstract":"<p><strong>Purpose of review: </strong>Anaphylaxis is a severe, potentially life-threatening allergic reaction that requires rapid identification and intervention. Current management includes early recognition, prompt administration of epinephrine, and immediate medical attention. However, challenges remain in accurate diagnosis, timely treatment, and personalized care. This article reviews the integration of artificial intelligence and machine learning in enhancing anaphylaxis management.</p><p><strong>Recent findings: </strong>Artificial intelligence and machine learning can analyze vast datasets to identify patterns and predict anaphylactic episodes, improve diagnostic accuracy through image and biomarker analysis, and personalize treatment plans. Artificial intelligence-powered wearable devices and decision support systems can facilitate real-time monitoring and early intervention. The ethical considerations of artificial intelligence use, including data privacy, transparency, and bias mitigation, are also discussed.</p><p><strong>Summary: </strong>Future directions include the development of predictive models, enhanced diagnostic tools, and artificial intelligence-driven educational resources. By leveraging artificial intelligence and machine learning, healthcare providers can improve the management of anaphylaxis, ensuring better patient outcomes and advancing personalized medicine.</p>","PeriodicalId":10956,"journal":{"name":"Current Opinion in Allergy and Clinical Immunology","volume":null,"pages":null},"PeriodicalIF":3.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141855108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Chronic urticaria: not only after COVID-19 vaccination. 慢性荨麻疹:不仅在接种COVID-19疫苗后出现。
IF 3 4区 医学
Current Opinion in Allergy and Clinical Immunology Pub Date : 2024-10-01 Epub Date: 2024-07-30 DOI: 10.1097/ACI.0000000000001019
Mona-Rita Yacoub, Arianna Ferlito, Eustachio Nettis
{"title":"Chronic urticaria: not only after COVID-19 vaccination.","authors":"Mona-Rita Yacoub, Arianna Ferlito, Eustachio Nettis","doi":"10.1097/ACI.0000000000001019","DOIUrl":"10.1097/ACI.0000000000001019","url":null,"abstract":"<p><strong>Purpose of review: </strong>To resume the current literature about vaccination and the onset of chronic urticaria.</p><p><strong>Recent findings: </strong>The recent large-scale vaccination against SARS-CoV-2 targeting elderly, adult and children, has highlighted how vaccines can trigger onset or exacerbation of chronic urticaria.</p><p><strong>Summary: </strong>COVID-19 vaccines may act as triggers in the development of chronic spontaneous urticaria. More data regarding the other vaccines are necessary to evaluate a similar potential role. Proper education of patients with vaccine-induced chronic urticaria is essential to avoid vaccination hesitancy.</p>","PeriodicalId":10956,"journal":{"name":"Current Opinion in Allergy and Clinical Immunology","volume":null,"pages":null},"PeriodicalIF":3.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141855110","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Adverse effects of anti-cancer biologics on the ocular surface. 抗癌生物制剂对眼表的不良影响。
IF 3 4区 医学
Current Opinion in Allergy and Clinical Immunology Pub Date : 2024-10-01 Epub Date: 2024-07-04 DOI: 10.1097/ACI.0000000000001007
Riham Shawer, Abraham Solomon
{"title":"Adverse effects of anti-cancer biologics on the ocular surface.","authors":"Riham Shawer, Abraham Solomon","doi":"10.1097/ACI.0000000000001007","DOIUrl":"10.1097/ACI.0000000000001007","url":null,"abstract":"<p><strong>Purpose of review: </strong>Cancer immunotherapy is one of the most emerging and rapidly growing fields.Ocular side effects associated with these therapies are common and can be present in up to 70% of patients.The cornea may be involved in different pathogenic mechanisms triggered by different immunotherapeutic agents, and corneal disease varies from mild symptoms to severe corneal ulceration and melting with visual loss.We aimed to review the incidence, mechanism, and management of ocular surface side effects in cancer patients receiving immunotherapy.</p><p><strong>Recent findings: </strong>With the recent use of immunotherapeutic agents in cancer patients, in particular immune checkpoint inhibitors (ICIs) and epidermal growth factor receptor (EGFR) inhibitors, ocular surface and corneal involvement are common side effects.These patients can be at risk of sight threatening complications that warrant prompt diagnosis and careful monitoring and management.</p><p><strong>Summary: </strong>Immunotherapy- related corneal complications in cancer patients are associated with a decreased quality of life. Prompt recognition and an interdisciplinary approach between ophthalmologists and oncologists are crucial to handle immune related ocular adverse events in these patients, in order to maintain ocular surface integrity and avoid a vision threatening complication.</p>","PeriodicalId":10956,"journal":{"name":"Current Opinion in Allergy and Clinical Immunology","volume":null,"pages":null},"PeriodicalIF":3.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141533935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The risk of anaphylaxis on holidays. 节假日发生过敏性休克的风险。
IF 3 4区 医学
Current Opinion in Allergy and Clinical Immunology Pub Date : 2024-10-01 Epub Date: 2024-08-02 DOI: 10.1097/ACI.0000000000001014
Erminia Ridolo, Alessandro Barone, Martina Ottoni, Francesca Nicoletta
{"title":"The risk of anaphylaxis on holidays.","authors":"Erminia Ridolo, Alessandro Barone, Martina Ottoni, Francesca Nicoletta","doi":"10.1097/ACI.0000000000001014","DOIUrl":"10.1097/ACI.0000000000001014","url":null,"abstract":"<p><strong>Purpose of review: </strong>The goal of this review is to summarize the potential causes of anaphylaxis in the different holiday contexts, providing practical suggestions aimed to mitigate the stress challenged by allergic patients because of unfamiliar situations.</p><p><strong>Recent findings: </strong>A regard was reserved to potential food triggers, particularly uncommon ones and typical of certain destinations, and to arthropods responsible for anaphylaxis.</p><p><strong>Summary: </strong>This review highlights the potential risk of anaphylaxis due to the unusual contexts more experienced during holidays (i.e., travels, outdoor activities and eating out). Moreover, it underlines the need for a further allergological education in these cases, in order to prepare allergic patients to avoid and manage undesired situations.</p>","PeriodicalId":10956,"journal":{"name":"Current Opinion in Allergy and Clinical Immunology","volume":null,"pages":null},"PeriodicalIF":3.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11356676/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141878523","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Hymenoptera venom allergy in children and adolescents. 儿童和青少年对膜翅目昆虫毒液过敏。
IF 3 4区 医学
Current Opinion in Allergy and Clinical Immunology Pub Date : 2024-10-01 Epub Date: 2024-08-12 DOI: 10.1097/ACI.0000000000001013
Francesca Norelli, Valentina Gueli, Patrizia Bonadonna
{"title":"Hymenoptera venom allergy in children and adolescents.","authors":"Francesca Norelli, Valentina Gueli, Patrizia Bonadonna","doi":"10.1097/ACI.0000000000001013","DOIUrl":"10.1097/ACI.0000000000001013","url":null,"abstract":"<p><strong>Purpose of review: </strong>This review will identify and summarize the published existing data pertaining specifically to Hymenoptera venom allergy in children and adolescents, highlighting the major studies currently available on venom immunotherapy (VIT) and its prognosis in children.</p><p><strong>Recent findings: </strong>The current review covers the incidence and prevalence of Hymenoptera venom allergy (HVA) in children, factors influencing occurrence and severity of reactions (age, sex, comorbidities, etc.), indications to perform diagnostic tests and start VIT in children, different existing VIT protocols and their safety and efficacy.</p><p><strong>Summary: </strong>Hymenoptera venom allergy is the second most common cause of anaphylaxis in children and it considerably affects quality of life. Cutaneous reactions are the most prevalent clinical presentation in children who usually have a more favourable prognosis than adult patients. However, studies on HVA in children and adolescents are still limited. Currently VIT is the only treatment able to modify the natural history of HVA in adults as well as in children, and to protect patients from systemic reactions after subsequent stings.</p>","PeriodicalId":10956,"journal":{"name":"Current Opinion in Allergy and Clinical Immunology","volume":null,"pages":null},"PeriodicalIF":3.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141916333","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Beyond the appearances: exploring complexities in anaphylaxis differential diagnosis. 超越表象:探索过敏性休克鉴别诊断的复杂性。
IF 3 4区 医学
Current Opinion in Allergy and Clinical Immunology Pub Date : 2024-10-01 Epub Date: 2024-07-24 DOI: 10.1097/ACI.0000000000001016
Stefania Nicola, Luca Lo Sardo, Richard Borrelli, Anna Quinternetto, Nicolò Rashidy, Luisa Brussino
{"title":"Beyond the appearances: exploring complexities in anaphylaxis differential diagnosis.","authors":"Stefania Nicola, Luca Lo Sardo, Richard Borrelli, Anna Quinternetto, Nicolò Rashidy, Luisa Brussino","doi":"10.1097/ACI.0000000000001016","DOIUrl":"10.1097/ACI.0000000000001016","url":null,"abstract":"<p><strong>Purpose of review: </strong>Anaphylaxis is a severe, and potentially life-threatening hypersensitivity reaction whose diagnosis is based on clinical signs and symptoms and their prompt recognition. The presence of mimics and unusual presentations necessitate a careful evaluation and expertise in the field, due to potential diagnostic errors and hence a delay in the treatment.The aim of this review is to analyze and make an overview of the potential differential diagnosis of anaphylaxis, focusing on the clinical challenges of recognizing these conditions effectively among similar others.</p><p><strong>Recent findings: </strong>The presence of mimics and unusual presentations of anaphylaxis necessitate a careful evaluation, emphasizing the importance of a comprehensive diagnostic approach.Tryptase is well known marker of mast cells activation, and a useful tool assisting the diagnosis of anaphylaxis, helping to differentiate it from atypical mimickers.</p><p><strong>Summary: </strong>The differential diagnosis of anaphylaxis comprises a very wide setting, and a systematic approach assessing different categories of cardiovascular, skin, respiratory airway, neuropsychiatric, and hematologic systems, can facilitate recognition of the correct diagnosis of this complex and life-threatening condition.</p>","PeriodicalId":10956,"journal":{"name":"Current Opinion in Allergy and Clinical Immunology","volume":null,"pages":null},"PeriodicalIF":3.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141855109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Genetic landscape of atopic dermatitis. 特应性皮炎的基因状况。
IF 3 4区 医学
Current Opinion in Allergy and Clinical Immunology Pub Date : 2024-10-01 Epub Date: 2024-06-24 DOI: 10.1097/ACI.0000000000001005
Lavinia Paternoster
{"title":"Genetic landscape of atopic dermatitis.","authors":"Lavinia Paternoster","doi":"10.1097/ACI.0000000000001005","DOIUrl":"10.1097/ACI.0000000000001005","url":null,"abstract":"<p><strong>Purpose of review: </strong>This review summarizes recent advances in identifying genetic risk factors for atopic dermatitis and how these genetic associations are being used to explore the causal relationships between atopic dermatitis and potential risk factors and downstream outcomes.</p><p><strong>Recent findings: </strong>A recent large-scale GWAS meta-analysis has identified 91 genetic loci associated with atopic dermatitis. Rare variant studies have also identified new gain-of-function or loss-of-function variants implicated in atopic dermatitis, particularly for FLG and STAT6/JAK1 . Finally, there has been a surge in utilizing genetic association data to investigate the causal relationships between atopic dermatitis and other traits. Mendelian randomization studies have found that various metabolites and gut microbiota are causal for atopic dermatitis and have causally implicate atopic dermatitis in the development of alopecia areata, diabetes, vascular dementia and some cancers.</p><p><strong>Summary: </strong>The past year has seen a huge increase in the genes implicated for atopic dermatitis and in the use of genetics to explore causal relationships. The latter requires caution in implementation and interpretation, but is a promising area of research. In the coming years, increasing the ethnic diversity of atopic dermatitis genetic studies would be very welcome and the translation of current genetic findings into new drugs will be an exciting area of development.</p>","PeriodicalId":10956,"journal":{"name":"Current Opinion in Allergy and Clinical Immunology","volume":null,"pages":null},"PeriodicalIF":3.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7616406/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141450010","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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