Current Paediatrics最新文献_第7页

ПРИКОРМ, ОСОБЕННОСТИ ВВЕДЕНИЯ. КЛИНИЧЕСКИЕ СЛУЧАИ 附属物，注射的特征。临床案例

Current Paediatrics Pub Date : 2017-09-28 DOI: 10.15690/VSP.V16I4.1777

Вера Алексеевна Скворцова, Татьяна Эдуардовна Боровик, Татьяна Владимировна Бушуева, Н. Г. Звонкова, Ольга Леонидовна Лукоянова, Елена Александровна Рославцева, Ирина Анатольевна Гусева

引用次数: 1

АУТОСОМНО-РЕЦЕССИВНАЯ ПЕРИФЕРИЧЕСКАЯ НЕЙРОПАТИЯ С НЕЙРОМИОТОНИЕЙ (ARAN-NM): ОПИСАНИЕ КЛИНИЧЕСКОГО СЛУЧАЯ, ПОДТВЕРЖДЕННОГО МУТАЦИЕЙ В ГЕНЕ HINT1 自体衰退边缘神经病变(ARAN-NM): HINT1基因突变证实的临床病例描述

Current Paediatrics Pub Date : 2017-09-27 DOI: 10.15690/VSP.V16I4.1780

Ольга Андреевна Клочкова, Алексей Львович Куренков, Н. В. Журкова, К. В. Савостьянов, И. С. Жанин, А. М. Мамедьяров, И. М. Тардова

{"title":"АУТОСОМНО-РЕЦЕССИВНАЯ ПЕРИФЕРИЧЕСКАЯ НЕЙРОПАТИЯ С НЕЙРОМИОТОНИЕЙ (ARAN-NM): ОПИСАНИЕ КЛИНИЧЕСКОГО СЛУЧАЯ, ПОДТВЕРЖДЕННОГО МУТАЦИЕЙ В ГЕНЕ HINT1","authors":"Ольга Андреевна Клочкова, Алексей Львович Куренков, Н. В. Журкова, К. В. Савостьянов, И. С. Жанин, А. М. Мамедьяров, И. М. Тардова","doi":"10.15690/VSP.V16I4.1780","DOIUrl":"https://doi.org/10.15690/VSP.V16I4.1780","url":null,"abstract":"Autosomal recessive peripheral neuropathy with neuromyotonia (ARAN-NM) is a relatively newly described disease associated with mutations in the HINT1 gene. It accounts for a significant part of the poorly differentiated forms of axonal polyneuropathies. We present the first in Russia description of the genetically confirmed case of ARAN-NM in a boy aged 14 years and 11 months without the hereditary-tainted anamnesis. On presentation, the patient experienced progressive distal muscular weakness, asymmetric foot deformity, gait disorders and minimal manifestations of neuromyotonia (stiffness in the fingers). During examination, we detected an increase in the level of creatine phosphokinase up to 635 U/l, a disturbance of conduction of motor and, to a lesser extent, sensory fibers of the peripheral nerves (according to the stimulation electromyography, EMG), denervation-reinnervation changes, single positive acute waves, fibrillation potentials, complex repeated discharge (according to the data of needle EMG). In the study of exome, a homozygous mutation c.110G>C, p.R37P was determined in exon 01 of the HINT1 gene, which confirmed the presence of ARAN-NM. A molecular-genetic examination of the patient's immediate relatives was carried out. The described case is compared with literature data. An overview of currently available information on ARAN-NM is provided. Diagnostic criteria of the disease are presented.","PeriodicalId":10919,"journal":{"name":"Current Paediatrics","volume":"1 1","pages":"326-333"},"PeriodicalIF":0.0,"publicationDate":"2017-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84518645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

ВСЕМ СПАСАТЬСЯ ОТ КОКСАКИ?! ИЛИ У СТРАХА ГЛАЗА ВЕЛИКИ 大家都离开考克萨基!或者恐惧有一双大眼睛

Current Paediatrics Pub Date : 2017-09-27 DOI: 10.15690/VSP.V16I4.1774

З. А. Алачева, О. Б. Рыбалка, Татьяна Владимировна Куличенко

引用次数: 1

ОПЫТ УСПЕШНОГО ПРИМЕНЕНИЯ ЭТАНЕРЦЕПТА У ПАЦИЕНТКИ С ПОЛИАРТИКУЛЯРНЫМ ВАРИАНТОМ ЮВЕНИЛЬНОГО ИДИОПАТИЧЕСКОГО АРТРИТА С ОБЗОРОМ ПРЕДИКТОРОВ ХОРОШЕГО ОТВЕТА НА ПРОВОДИМУЮ ТЕРАПИЮ 患者成功使用异位性视网膜炎的经验，对治疗的前导反应良好的青少年特发性关节炎进行了审查。

Current Paediatrics Pub Date : 2017-09-27 DOI: 10.15690/VSP.V16I4.1779

А. В. Карасёва, Екатерина Иосифовна Алексеева, Т. М. Дворяковская

引用次数: 0

ГЛЮКОКОРТИКОСТЕРОИДНАЯ ТЕРАПИЯ И ФИЗИЧЕСКОЕ РАЗВИТИЕ ДЕТЕЙ СО СТЕРОИДЧУВСТВИТЕЛЬНЫМ НЕФРОТИЧЕСКИМ СИНДРОМОМ: РЕЗУЛЬТАТЫ РЕТРОСПЕКТИВНОГО ИССЛЕДОВАНИЯ 血糖皮质激素疗法和患有类固醇肾功能障碍儿童的身体发育:回顾性研究的结果

Current Paediatrics Pub Date : 2017-09-27 DOI: 10.15690/VSP.V16I4.1775

Ольга Александровна Жданова

{"title":"ГЛЮКОКОРТИКОСТЕРОИДНАЯ ТЕРАПИЯ И ФИЗИЧЕСКОЕ РАЗВИТИЕ ДЕТЕЙ СО СТЕРОИДЧУВСТВИТЕЛЬНЫМ НЕФРОТИЧЕСКИМ СИНДРОМОМ: РЕЗУЛЬТАТЫ РЕТРОСПЕКТИВНОГО ИССЛЕДОВАНИЯ","authors":"Ольга Александровна Жданова","doi":"10.15690/VSP.V16I4.1775","DOIUrl":"https://doi.org/10.15690/VSP.V16I4.1775","url":null,"abstract":"Background. Body weight gain and growth retardation are common side effects of prolonged glucocorticosteroid therapy in children. Time for the appearance and elimination of glucocorticosteroid obesity as well as growth disorders require further investigations. Objective . Our aim was to study the relationship between glucocorticosteroid therapy and changes in physical development indices of children with steroid-sensitive nephrotic syndrome (SSNS). Methods. We carried out a retrospective study of case records of patients with SSNS hospitalized in 2011–2014. Treatment of children was carried out in accordance with the Federal Clinical Guidelines. The Z-score (ANTHRO Plus) was determined for body length (height), body weight, body mass index and correlation of physical development indices with a cumulative dose and duration of glucocorticosteroid therapy. Results. We analyzed data on the treatment of 31 children, 18 of them received glucocorticosteroids for 6 months (Group 1), 13 of them did not receive glucocorticosteroids 6 months (Group 2). The Z-score of body weight in children in these groups was 1.64 ± 1.54 and 0.05 ± 1.19 (p = 0.004), Z-score of body mass index was 1.85 ± 1.64 and -0.54 ± 1.14, respectively (p < 0.001). Excess body weight and obesity were only observed in children of Group 1 (in 6 and 9, respectively). The Z-score of the body length of patients in groups 1 and 2 were comparable and did not differ from normal values (0.34 ± 1.08 and 0.52 ± 1.12, respectively, p = 0.655). Correlation of Z-score values of the body length and cumulative doses of glucocorticosteroids was noted (r = -0.87, p < 0.001). Conclusion. Long-term (at least 6 months) glucocorticosteroid intake is associated with the development of overweight and obesity in most children with SSNS. In patients who did not use hormonal drugs for 6 months, normal body weight values were recorded. The height of children with SSNS was within the range of normal values.","PeriodicalId":10919,"journal":{"name":"Current Paediatrics","volume":"74 1","pages":"291-296"},"PeriodicalIF":0.0,"publicationDate":"2017-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76477554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

ДИАГНОСТИЧЕСКАЯ ЦЕННОСТЬ ОПРЕДЕЛЕНИЯ УРОВНЯ ПРОКАЛЬЦИТОНИНА В ПРАКТИКЕ ИНФЕКЦИОНИСТА 检测感染者实践中的普罗尔霉素水平的诊断价值

Current Paediatrics Pub Date : 2017-09-27 DOI: 10.15690/VSP.V16I4.1781

А. С. Полякова, М. БакрадзеД., Владимир Кириллович Таточенко, Диана Джансуховна Гадлия

{"title":"ДИАГНОСТИЧЕСКАЯ ЦЕННОСТЬ ОПРЕДЕЛЕНИЯ УРОВНЯ ПРОКАЛЬЦИТОНИНА В ПРАКТИКЕ ИНФЕКЦИОНИСТА","authors":"А. С. Полякова, М. БакрадзеД., Владимир Кириллович Таточенко, Диана Джансуховна Гадлия","doi":"10.15690/VSP.V16I4.1781","DOIUrl":"https://doi.org/10.15690/VSP.V16I4.1781","url":null,"abstract":"Considering the colossal frequency of infectious diseases among children, pediatricians face the task not only to cure the patient but also to do this as soon as possible with an individual approach to each child. One of the main aspects of diagnosis in febrile children is the differentiation of a bacterial infection from viral one in order to assign timely antibiotic therapy to one patient and to prevent excessive assignment to others. In addition, an important point is to identify the category of patients with a severe bacterial infection, which requires the most attention. The article reveals the main points of a differential diagnosis of bacterial and viral infections, considering clinical symptoms and laboratory parameters: the concentration of procalcitonin, C-reactive protein, and leukocytes. The limits of procalcitonin values for various nosological forms and the possibility of their use in terms of the appointment, continuation or replacement of antibacterial therapy in pediatric practice are described.","PeriodicalId":10919,"journal":{"name":"Current Paediatrics","volume":"34 1","pages":"334-341"},"PeriodicalIF":0.0,"publicationDate":"2017-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72762523","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

ПРОФИЛАКТИКА ТРЕЩИН СОСКА МОЛОЧНОЙ ЖЕЛЕЗЫ В РАННИЙ ПОСЛЕРОДОВЫЙ ПЕРИОД 预防产后早期乳头骨折

Current Paediatrics Pub Date : 2017-09-27 DOI: 10.15690/VSP.V16I4.1776

М. Л. Травина, А. Г. Попов, С. А. Попов, Е. В. Куликова

引用次数: 6

ВАКЦИНАЦИЯ ПРОТИВ РОТАВИРУСНОЙ ИНФЕКЦИИ: 10-ЛЕТНИЙ МИРОВОЙ ОПЫТ УСПЕШНОГО ПРИМЕНЕНИЯ

Current Paediatrics Pub Date : 2017-09-27 DOI: 10.15690/VSP.V16I4.1773

L. Namazova-Baranova, M. V. Fedoseenko, E. Vishneva, V. K. Tatochenko, L. Selimzianova, D. Chemakina

引用次数: 6

ОПЫТ ПЕРЕКЛЮЧЕНИЯ НА ВТОРОЙ ИНГИБИТОР TNF ПАЦИЕНТКИ С ТЯЖЕЛЫМ ТЕЧЕНИЕМ ЮНОШЕСКОГО ПОЛИАРТРИТА И РЕЗИСТЕНТНОСТЬЮ К ПЕРВОМУ TNF-БЛОКАТОРУ1 将TNF抑制剂转移到患者的第二种TNF抑制剂的经验，其青少年多关节炎严重，对TNF阻滞剂具有抵抗力。

Current Paediatrics Pub Date : 2017-09-27 DOI: 10.15690/VSP.V16I4.1778

Екатерина Иосифовна Алексеева, Т. М. Дворяковская, Рина Валериановна Денисова, О. Л. Ломакина, А. В. Карасёва

{"title":"ОПЫТ ПЕРЕКЛЮЧЕНИЯ НА ВТОРОЙ ИНГИБИТОР TNF ПАЦИЕНТКИ С ТЯЖЕЛЫМ ТЕЧЕНИЕМ ЮНОШЕСКОГО ПОЛИАРТРИТА И РЕЗИСТЕНТНОСТЬЮ К ПЕРВОМУ TNF-БЛОКАТОРУ1","authors":"Екатерина Иосифовна Алексеева, Т. М. Дворяковская, Рина Валериановна Денисова, О. Л. Ломакина, А. В. Карасёва","doi":"10.15690/VSP.V16I4.1778","DOIUrl":"https://doi.org/10.15690/VSP.V16I4.1778","url":null,"abstract":"The article presents a case of a severe progressive course of polyarticular juvenile idiopathic arthritis, debuting at an early age, refractory to the therapy with methotrexate, cyclosporine, and glucocorticosteroids. A clinical example demonstrates that switching to the second TNF inhibitor in the case of developing secondary resistance to the first drug from this group provides restoration of the therapeutic effect and is not accompanied by serious adverse events. Six months after switching to adalimumab, due to the «escape» of the effect of etanercept, the inflammatory changes in the patient were reversed; the volume of movements in the joints increased, and the laboratory parameters of the disease activity were normalized. After 1 year, there was a remission of the disease. The child managed to completely eliminate glucocorticosteroids for oral ingestion. The duration of the joint syndrome remission was 3 years. Adverse events were not serious and did not become a basis for drug withdrawal.","PeriodicalId":10919,"journal":{"name":"Current Paediatrics","volume":"84 1","pages":"314-320"},"PeriodicalIF":0.0,"publicationDate":"2017-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79113046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

ЗАИМСТВОВАНИЯ СОБСТВЕННЫХ ТЕКСТОВ (САМОПЛАГИАТ) В РУКОПИСЯХ, ПРЕДСТАВЛЕННЫХ НА РАССМОТРЕНИЕ В НАУЧНЫЙ ЖУРНАЛ: РЕКОМЕНДАЦИИ ПО ФОРМУЛИРОВАНИЮ РЕДАКЦИОННОЙ ПОЛИТИКИ 在科学期刊上提交的手稿中(自我剽窃)借用自己的文本:制定编辑政策的建议

Current Paediatrics Pub Date : 2017-09-27 DOI: 10.15690/VSP.V16I4.1772

Руслан Темирсултанович Сайгитов

引用次数: 0