А. В. Карасёва, Екатерина Иосифовна Алексеева, Т. М. Дворяковская
{"title":"患者成功使用异位性视网膜炎的经验,对治疗的前导反应良好的青少年特发性关节炎进行了审查。","authors":"А. В. Карасёва, Екатерина Иосифовна Алексеева, Т. М. Дворяковская","doi":"10.15690/VSP.V16I4.1779","DOIUrl":null,"url":null,"abstract":"The article presents a case of polyarticular juvenile idiopathic arthritis resistant to methotrexate therapy and nonsteroidal antiinflammatory drugs. The child was prescribed a tumor necrosis factor inhibitor etanercept at a dose of 0.4 mg/kg body weight2 times/week. The treatment with etanercept induced remission of the disease, ensured the function restoration in the joints. The predictors of a good response to etanercept were the younger age, the short course of the disease, the use of a small number of immunosuppressants before prescription of etanercept, the absence of concomitant use of glucocorticosteroids, and the absence of uveitis.","PeriodicalId":10919,"journal":{"name":"Current Paediatrics","volume":"80 1","pages":"321-325"},"PeriodicalIF":0.0000,"publicationDate":"2017-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"ОПЫТ УСПЕШНОГО ПРИМЕНЕНИЯ ЭТАНЕРЦЕПТА У ПАЦИЕНТКИ С ПОЛИАРТИКУЛЯРНЫМ ВАРИАНТОМ ЮВЕНИЛЬНОГО ИДИОПАТИЧЕСКОГО АРТРИТА С ОБЗОРОМ ПРЕДИКТОРОВ ХОРОШЕГО ОТВЕТА НА ПРОВОДИМУЮ ТЕРАПИЮ\",\"authors\":\"А. В. Карасёва, Екатерина Иосифовна Алексеева, Т. М. Дворяковская\",\"doi\":\"10.15690/VSP.V16I4.1779\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The article presents a case of polyarticular juvenile idiopathic arthritis resistant to methotrexate therapy and nonsteroidal antiinflammatory drugs. The child was prescribed a tumor necrosis factor inhibitor etanercept at a dose of 0.4 mg/kg body weight2 times/week. The treatment with etanercept induced remission of the disease, ensured the function restoration in the joints. The predictors of a good response to etanercept were the younger age, the short course of the disease, the use of a small number of immunosuppressants before prescription of etanercept, the absence of concomitant use of glucocorticosteroids, and the absence of uveitis.\",\"PeriodicalId\":10919,\"journal\":{\"name\":\"Current Paediatrics\",\"volume\":\"80 1\",\"pages\":\"321-325\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2017-09-27\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Current Paediatrics\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.15690/VSP.V16I4.1779\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current Paediatrics","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.15690/VSP.V16I4.1779","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
ОПЫТ УСПЕШНОГО ПРИМЕНЕНИЯ ЭТАНЕРЦЕПТА У ПАЦИЕНТКИ С ПОЛИАРТИКУЛЯРНЫМ ВАРИАНТОМ ЮВЕНИЛЬНОГО ИДИОПАТИЧЕСКОГО АРТРИТА С ОБЗОРОМ ПРЕДИКТОРОВ ХОРОШЕГО ОТВЕТА НА ПРОВОДИМУЮ ТЕРАПИЮ
The article presents a case of polyarticular juvenile idiopathic arthritis resistant to methotrexate therapy and nonsteroidal antiinflammatory drugs. The child was prescribed a tumor necrosis factor inhibitor etanercept at a dose of 0.4 mg/kg body weight2 times/week. The treatment with etanercept induced remission of the disease, ensured the function restoration in the joints. The predictors of a good response to etanercept were the younger age, the short course of the disease, the use of a small number of immunosuppressants before prescription of etanercept, the absence of concomitant use of glucocorticosteroids, and the absence of uveitis.