{"title":"Intracranial Pressure and Its Relationship to Glaucoma","authors":"Brandon VanderZee, B. Shafer, John P Berdahl","doi":"10.1007/s40135-021-00267-z","DOIUrl":"https://doi.org/10.1007/s40135-021-00267-z","url":null,"abstract":"","PeriodicalId":10836,"journal":{"name":"Current Ophthalmology Reports","volume":"9 1","pages":"83 - 87"},"PeriodicalIF":0.9,"publicationDate":"2021-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s40135-021-00267-z","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43911171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Autologous Blood Products: When, Where, and How?","authors":"Arianna A. Tovar, Alfonso L. Sabater","doi":"10.1007/s40135-021-00266-0","DOIUrl":"https://doi.org/10.1007/s40135-021-00266-0","url":null,"abstract":"","PeriodicalId":10836,"journal":{"name":"Current Ophthalmology Reports","volume":"9 1","pages":"48 - 56"},"PeriodicalIF":0.9,"publicationDate":"2021-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s40135-021-00266-0","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49018439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Update on the Management of Ocular Surface Squamous Neoplasia.","authors":"Umangi Patel, Carol L Karp, Sander R Dubovy","doi":"10.1007/s40135-020-00260-y","DOIUrl":"https://doi.org/10.1007/s40135-020-00260-y","url":null,"abstract":"<p><strong>Purpose of review: </strong>To review and update the latest findings in diagnosis and management of ocular surface squamous neoplasia (OSSN).</p><p><strong>Recent findings: </strong>OSSN is the most common anterior segment neoplastic disease process. Several ocular surface imaging techniques have been developed for the early diagnosis and management of clinical and subclinical ocular surface squamous neoplasia, including high-resolution optical coherence tomography (HR-OCT), in vivo confocal microscopy, and ultrasound biomicroscopy. Treatment modalities include both surgical and medical management, with a recent trend towards primary and adjunctive pharmacotherapy.</p><p><strong>Summary: </strong>There is increasing use of HR-OCT for the diagnosis and monitoring of clinical and subclinical OSSN lesions. Topical pharmacotherapy agents, including interferon α-2b, 5-fluorouracil, and mitomycin C, have demonstrable efficacy in the treatment of OSSN and their use may be dictated based upon tumor factors, patient factors, cost, and side effect profile. Both surgical excision and adjunctive topical medications have excellent success, with the favored treatment method trending towards topical pharmacotherapy as primary therapy.</p>","PeriodicalId":10836,"journal":{"name":"Current Ophthalmology Reports","volume":"9 1","pages":"7-15"},"PeriodicalIF":0.9,"publicationDate":"2021-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s40135-020-00260-y","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39643657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Uveal Melanoma: A Review of Prognostic Factors for Metastases","authors":"Emily Chang, H. Demirci","doi":"10.1007/s40135-020-00261-x","DOIUrl":"https://doi.org/10.1007/s40135-020-00261-x","url":null,"abstract":"","PeriodicalId":10836,"journal":{"name":"Current Ophthalmology Reports","volume":"1 1","pages":"1-6"},"PeriodicalIF":0.9,"publicationDate":"2021-01-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s40135-020-00261-x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43622509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Clinical Studies of COMET for Total LSCD: a Review of the Methods and Molecular Markers for Follow-Up Characterizations","authors":"E. Attico, G. Galaverni, G. Pellegrini","doi":"10.1007/s40135-020-00263-9","DOIUrl":"https://doi.org/10.1007/s40135-020-00263-9","url":null,"abstract":"","PeriodicalId":10836,"journal":{"name":"Current Ophthalmology Reports","volume":"9 1","pages":"25-37"},"PeriodicalIF":0.9,"publicationDate":"2021-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s40135-020-00263-9","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43383944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Malignant Orbital Tumors: Current Approach to Diagnosis and Management","authors":"Jane S. Kim, Amal Al-lozi, Ilya M. Leyngold","doi":"10.1007/s40135-020-00262-w","DOIUrl":"https://doi.org/10.1007/s40135-020-00262-w","url":null,"abstract":"","PeriodicalId":10836,"journal":{"name":"Current Ophthalmology Reports","volume":"1 1","pages":"1-9"},"PeriodicalIF":0.9,"publicationDate":"2021-01-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s40135-020-00262-w","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49373422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Impact of the COVID-19 Pandemic on Refractive Surgery.","authors":"Matthew Bickford, Karolinne Rocha","doi":"10.1007/s40135-021-00280-2","DOIUrl":"https://doi.org/10.1007/s40135-021-00280-2","url":null,"abstract":"<p><strong>Purpose of review: </strong>In this article, we review the impact of the COVID-19 pandemic on refractive surgery.</p><p><strong>Recent findings: </strong>COVID-19 infection frequently causes eye symptoms, most commonly conjunctivitis or mild irritation. While virus can be detected in tears of symptomatic patients, the risk of transmission via this route appears low.</p><p><strong>Summary: </strong>Refractive surgery consultations were significantly reduced during the pandemic; however, volume is rebounding quickly likely due to a number of lifestyle, health, and financial factors. Laser refractive and intraocular surgery likely confer a low risk of virus spread, especially in asymptomatic patients. Screening prior to the refractive consultation and surface disinfection in the clinic and operating room can help reduce transmission risk further.</p>","PeriodicalId":10836,"journal":{"name":"Current Ophthalmology Reports","volume":"9 4","pages":"127-132"},"PeriodicalIF":0.9,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8532571/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39579475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S Tammy Hsu, Arathi Ponugoti, Jordan D Deaner, Lejla Vajzovic
{"title":"Update on Retinal Drug Toxicities.","authors":"S Tammy Hsu, Arathi Ponugoti, Jordan D Deaner, Lejla Vajzovic","doi":"10.1007/s40135-021-00277-x","DOIUrl":"https://doi.org/10.1007/s40135-021-00277-x","url":null,"abstract":"<p><strong>Purpose of review: </strong>This review aims to provide an update on the clinical presentations and diagnostic findings of drug-induced retinal toxicities.</p><p><strong>Recent findings: </strong>Several newly FDA-approved medications have been associated with acute retinal toxicities, including brolucizumab, MEK inhibitors, ulixertinib, and FGFR inhibitors. Additionally, as previously believed-to-be well-tolerated medications, such as pentosan sulfate sodium, anti-retroviral therapies, and certain intraoperative ocular medications, are used more frequently or for longer periods of time, associated toxic retinopathies and inflammatory reactions have been reported. Finally, advances in ocular imaging have revealed novel findings in hydroxychloroquine and tamoxifen maculopathies.</p><p><strong>Summary: </strong>Discovery of new medications, increased frequency of use, and longer-term use have led to increased reports of retinal toxicities. Advances in retinal imaging have allowed for earlier detection of subclinical changes associated with these medications, which may help prevent progression of disease. However, more research is needed to determine the point at which vision loss becomes irreversible. Risks and benefits must be assessed prior to discontinuation of the offending, but potentially lifesaving, therapy.</p>","PeriodicalId":10836,"journal":{"name":"Current Ophthalmology Reports","volume":"9 4","pages":"168-177"},"PeriodicalIF":0.9,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8688906/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39764723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Impact of SARS-CoV-2 on Ocular Surface Pathology and Treatment Practices: a Review.","authors":"Sila Bal, James Chodosh, Nandini Venkateswaran","doi":"10.1007/s40135-021-00271-3","DOIUrl":"https://doi.org/10.1007/s40135-021-00271-3","url":null,"abstract":"<p><strong>Purpose of review: </strong>The ocular surface is a potential site of ocular involvement by SARS-CoV-2 infection. We performed a review of the literature to understand the pathogenesis of SARS-CoV-2 disease manifestations on the ocular surface as well as to elucidate emerging treatment patterns and practice changes during the COVID-19 pandemic.</p><p><strong>Recent findings: </strong>The ocular manifestations of SARS-CoV-2 are likely limited to a mild and transient conjunctivitis. Other manifestations have not been validated in larger cohorts. Ocular surface tissue should be considered potentially infectious due to the presence of host receptors on surface tissues. The availability of donor tissue in lower-middle income countries has been greatly impacted by the pandemic and would benefit from further investigation into transmissibility through donor tissue.</p><p><strong>Summary: </strong>Transmission of SARS-CoV-2 through the ocular surface has yet to be confirmed. The most common ocular manifestation is a mild conjunctivitis. Ocular surface surgeons face specific challenges in the use of donor tissues and aerosolizing procedures and have adapted practice patterns accordingly.</p>","PeriodicalId":10836,"journal":{"name":"Current Ophthalmology Reports","volume":"9 3","pages":"77-82"},"PeriodicalIF":0.9,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s40135-021-00271-3","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39299924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Monica K Ertel, Malik Y Kahook, Cara E Capitena Young
{"title":"The Future Is Now: Incorporating Telemedicine into Glaucoma Care.","authors":"Monica K Ertel, Malik Y Kahook, Cara E Capitena Young","doi":"10.1007/s40135-021-00269-x","DOIUrl":"https://doi.org/10.1007/s40135-021-00269-x","url":null,"abstract":"<p><strong>Purpose of review: </strong>The field of teleglaucoma has expanded rapidly in recent years with several large-scale teleglaucoma screening programs in existence throughout the world. Additionally, teleglaucoma programs for use in disease management are under study. The limited access to care that resulted from the COVID-19 pandemic highlighted the need for expansion of such programs. This article reviews the literature on teleglaucoma for screening and management of glaucoma, discussing considerations for incorporating teleglaucoma into clinical practice.</p><p><strong>Recent findings: </strong>Teleglaucoma screening reduces the rate of false-positive referrals and can accurately screen at-risk populations with accuracy similar to in-person screening. The use of teleglaucoma for the management of glaucoma shows promise for low-risk patients with early disease. Furthermore, teleglaucoma is cost-effective and reduces travel burden for patients resulting in high patient satisfaction.</p><p><strong>Summary: </strong>Teleglaucoma offers potential for improving access to glaucoma care, reducing the burden on patients and health care systems.</p>","PeriodicalId":10836,"journal":{"name":"Current Ophthalmology Reports","volume":"9 3","pages":"88-95"},"PeriodicalIF":0.9,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s40135-021-00269-x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39178173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}