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Current Ophthalmology Reports最新文献

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Sight of Action: the Rationale and Evolution of Gene Therapy Approaches to the Treatment of Retinal Diseases 行动视野：视网膜疾病基因治疗方法的原理和发展
IF 0.9
Current Ophthalmology Reports Pub Date : 2020-10-28 DOI: 10.1007/s40135-020-00255-9
K. Woodburn, Sharmila Vijay, M. Blumenkranz
{"title":"Sight of Action: the Rationale and Evolution of Gene Therapy Approaches to the Treatment of Retinal Diseases","authors":"K. Woodburn, Sharmila Vijay, M. Blumenkranz","doi":"10.1007/s40135-020-00255-9","DOIUrl":"https://doi.org/10.1007/s40135-020-00255-9","url":null,"abstract":"","PeriodicalId":10836,"journal":{"name":"Current Ophthalmology Reports","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2020-10-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s40135-020-00255-9","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47737296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Corneal Neurotization and Novel Medical Therapies for Neurotrophic Keratopathy 神经营养性角膜病变的角膜神经化和新的药物治疗
IF 0.9
Current Ophthalmology Reports Pub Date : 2020-09-23 DOI: 10.1007/s40135-020-00254-w
Tatiana R. Rosenblatt, C. Sears, Ji Kwan Park, A. Kossler
{"title":"Corneal Neurotization and Novel Medical Therapies for Neurotrophic Keratopathy","authors":"Tatiana R. Rosenblatt, C. Sears, Ji Kwan Park, A. Kossler","doi":"10.1007/s40135-020-00254-w","DOIUrl":"https://doi.org/10.1007/s40135-020-00254-w","url":null,"abstract":"","PeriodicalId":10836,"journal":{"name":"Current Ophthalmology Reports","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2020-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s40135-020-00254-w","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43012886","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Descemet Membrane Endothelial Keratoplasty in Asian Eyes 视网膜膜内皮角膜移植术在亚洲人眼中的应用
IF 0.9
Current Ophthalmology Reports Pub Date : 2020-09-21 DOI: 10.1007/s40135-020-00256-8
Toshiki Shimizu, S. Yamagami, N. Mizuki, T. Hayashi
{"title":"Descemet Membrane Endothelial Keratoplasty in Asian Eyes","authors":"Toshiki Shimizu, S. Yamagami, N. Mizuki, T. Hayashi","doi":"10.1007/s40135-020-00256-8","DOIUrl":"https://doi.org/10.1007/s40135-020-00256-8","url":null,"abstract":"","PeriodicalId":10836,"journal":{"name":"Current Ophthalmology Reports","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2020-09-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s40135-020-00256-8","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48065905","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Effect of Intravitreal Injections on Retinal Imaging Metrics in Glaucomatous and Non-Glaucomatous Eyes. 玻璃体内注射对青光眼和非青光眼视网膜成像指标的影响。
IF 0.9
Current Ophthalmology Reports Pub Date : 2020-09-01 Epub Date: 2020-06-04 DOI: 10.1007/s40135-020-00235-z
Ronaldo Nuesi, Swarup S Swaminathan
{"title":"Effect of Intravitreal Injections on Retinal Imaging Metrics in Glaucomatous and Non-Glaucomatous Eyes.","authors":"Ronaldo Nuesi,&nbsp;Swarup S Swaminathan","doi":"10.1007/s40135-020-00235-z","DOIUrl":"https://doi.org/10.1007/s40135-020-00235-z","url":null,"abstract":"<p><strong>Purpose of review: </strong>To summarize the available literature on retinal imaging metrics in the context of intravitreal injections in glaucomatous and non-glaucomatous eyes.</p><p><strong>Recent findings: </strong>The retinal nerve fiber layer (RNFL) in injected non-glaucomatous eyes appears to thin at a similar rate to uninjected fellow eyes. A total of four studies evaluating RNFL thinning in injected glaucomatous eyes yielded mixed results, with more recent longitudinal investigations suggesting a potential association. The ganglion cell-inner plexiform layer is also being studied as a potential endpoint in both glaucomatous and non-glaucomatous eyes following intravitreal injections.</p>","PeriodicalId":10836,"journal":{"name":"Current Ophthalmology Reports","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2020-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s40135-020-00235-z","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25493498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
Diving Deep into Deep Learning: An Update on Artificial Intelligence in Retina. 深度学习:视网膜人工智能的最新进展。
IF 0.9
Current Ophthalmology Reports Pub Date : 2020-09-01 Epub Date: 2020-06-07 DOI: 10.1007/s40135-020-00240-2
Brian E Goldhagen, Hasenin Al-Khersan
{"title":"Diving Deep into Deep Learning: An Update on Artificial Intelligence in Retina.","authors":"Brian E Goldhagen,&nbsp;Hasenin Al-Khersan","doi":"10.1007/s40135-020-00240-2","DOIUrl":"https://doi.org/10.1007/s40135-020-00240-2","url":null,"abstract":"<p><strong>Purpose of review: </strong>In the present article, we will provide an understanding and review of artificial intelligence in the subspecialty of retina and its potential applications within the specialty.</p><p><strong>Recent findings: </strong>Given the significant use of diagnostic imaging within retina, this subspecialty is a fitting area for the incorporation of artificial intelligence. Researchers have aimed at creating models to assist in the diagnosis and management of retinal disease as well as in the prediction of disease course and treatment response. Most of this work thus far has focused on diabetic retinopathy, age-related macular degeneration, and retinopathy of prematurity, although other retinal diseases have started to be explored as well.</p><p><strong>Summary: </strong>Artificial intelligence is well-suited to transform the practice of ophthalmology. A basic understanding of the technology is important for its effective implementation and growth.</p>","PeriodicalId":10836,"journal":{"name":"Current Ophthalmology Reports","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2020-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s40135-020-00240-2","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38736748","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 7
Retinal Tamponades: Current Uses and Future Technologies. 视网膜填塞:当前用途和未来技术。
IF 0.9
Current Ophthalmology Reports Pub Date : 2020-09-01 Epub Date: 2020-07-04 DOI: 10.1007/s40135-020-00247-9
Avnish Deobhakta, Richard Rosen
{"title":"Retinal Tamponades: Current Uses and Future Technologies.","authors":"Avnish Deobhakta,&nbsp;Richard Rosen","doi":"10.1007/s40135-020-00247-9","DOIUrl":"https://doi.org/10.1007/s40135-020-00247-9","url":null,"abstract":"<p><strong>Purpose of review: </strong>In this article, the current use and limitations of existing retinal tamponades are discussed. Potential novel developments that address those limitations are subsequently highlighted, along with areas of future improvements.</p><p><strong>Recent findings: </strong>While retinal tamponades have existed for decades and improved the treatment of retinal detachments, many problems still exist with their use, including inadequate tamponade of the inferior retina, toxicity from retained heavy liquids, glaucoma, and keratopathy, among others. New advancements in the components of heavy liquids and vitreous substitutes aim to mitigate those issues.</p><p><strong>Summary: </strong>Existing retinal tamponades, including perflurocarbon heavy liquids, fluorinated gases, and silicone oil, have specific limitations that cause potentially avoidable morbidity. New developments, such as heavy silicone oil, novel vitreous gels, and future avenues of approach, such as potentially reabsorbing heavy liquids may help increase our ability to treat retinal detachments with fewer complications.</p>","PeriodicalId":10836,"journal":{"name":"Current Ophthalmology Reports","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2020-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s40135-020-00247-9","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25519521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 8
Optical Coherence Tomography: Critical Tool to Manage Expectations after Cataract Extraction. 光学相干断层扫描:管理白内障摘除后期望的关键工具。
IF 0.9
Current Ophthalmology Reports Pub Date : 2020-09-01 Epub Date: 2020-06-06 DOI: 10.1007/s40135-020-00243-z
Raquel Goldhardt, Bradley Simon Rosen
{"title":"Optical Coherence Tomography: Critical Tool to Manage Expectations after Cataract Extraction.","authors":"Raquel Goldhardt,&nbsp;Bradley Simon Rosen","doi":"10.1007/s40135-020-00243-z","DOIUrl":"https://doi.org/10.1007/s40135-020-00243-z","url":null,"abstract":"<p><strong>Purpose of review: </strong>To review evidence on the utility of spectral domain optical coherence tomography (SD-OCT) in evaluating retinal structure prior cataract surgery and highlight new technologies that can assess retinal function perioperatively.</p><p><strong>Findings: </strong>SD-OCT detected clinically unsuspected macular pathology in 4.6-25% of individuals in the pre-operative cataract evaluation. The most common findings were epiretinal membrane and macular degeneration with frequencies that varied by population studied. These conditions have been associated with complication after surgery (e.g. macular edema, visual dissatisfaction). As such, findings on SD-OCT may impact the informed consent process, alter IOL selection, and provide realistic postoperative vision expectations. Other technologies that assess retinal function, such as microperimetry and multifocal ERG are beginning to be studied but their utility in the pre-operative cataract evaluation is not yet known.</p><p><strong>Summary: </strong>SD-OCT should be incorporated as a routine test prior to surgery to manage patient expectations and assist with optimal IOL selection, as even individuals with a seemingly normal clinical exam may have macular pathology. SD-OCT is the most established method for evaluating retinal anatomy and offers the benefits of a reduction in cases with missed macular pathology and fewer postoperative visual surprises.</p>","PeriodicalId":10836,"journal":{"name":"Current Ophthalmology Reports","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2020-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s40135-020-00243-z","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38526622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
Topical Steroids in Management of Dry Eye Disease 局部类固醇治疗干眼症
IF 0.9
Current Ophthalmology Reports Pub Date : 2020-08-29 DOI: 10.1007/s40135-020-00249-7
Hayley Favre, S. Lahoti, Nasser G. Issa, Daniel A. Johnson, A. Kheirkhah
{"title":"Topical Steroids in Management of Dry Eye Disease","authors":"Hayley Favre, S. Lahoti, Nasser G. Issa, Daniel A. Johnson, A. Kheirkhah","doi":"10.1007/s40135-020-00249-7","DOIUrl":"https://doi.org/10.1007/s40135-020-00249-7","url":null,"abstract":"","PeriodicalId":10836,"journal":{"name":"Current Ophthalmology Reports","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2020-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s40135-020-00249-7","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47481803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Modern principles of the diabetic macular edema management 糖尿病性黄斑水肿的现代治疗原则
IF 0.9
Current Ophthalmology Reports Pub Date : 2020-08-24 DOI: 10.17816/OV33036
N. K. Mazurina, G. Stolyarenko
{"title":"Modern principles of the diabetic macular edema management","authors":"N. K. Mazurina, G. Stolyarenko","doi":"10.17816/OV33036","DOIUrl":"https://doi.org/10.17816/OV33036","url":null,"abstract":"Diabetes mellitus and diabetic retinal lesions are a global challenge for healthcare systems and one of the leading causes of severe vision loss among the working age population. Retinal laser coagulation remained the standard of therapy and the only possible treatment for diabetic macular edema (DME) in the 80-90s of the last century. The introduction of anti-VEGF therapy and glucocorticoids into the wide practice has significantly expanded the range of possibilities of DME treatment, allowing not only to stabilize patients vision, but also to improve it. The analyses of the large randomized clinical trials results are made and presented in this article, that highlight the basic principles of the contemporary DME treatment. This information is intended to help the ophthalmologist to develop the most optimal approach to treatment, considering the individual characteristics of each patient and the evidence-based efficacy and safety data of different methods.","PeriodicalId":10836,"journal":{"name":"Current Ophthalmology Reports","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2020-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90537334","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Emerging Technologies to Solve the Key Issues in Endothelial Keratoplasty 解决角膜内皮移植术关键问题的新兴技术
IF 0.9
Current Ophthalmology Reports Pub Date : 2020-08-24 DOI: 10.1007/s40135-020-00251-z
K. Brown, G. Dusting, M. Daniell
{"title":"Emerging Technologies to Solve the Key Issues in Endothelial Keratoplasty","authors":"K. Brown, G. Dusting, M. Daniell","doi":"10.1007/s40135-020-00251-z","DOIUrl":"https://doi.org/10.1007/s40135-020-00251-z","url":null,"abstract":"","PeriodicalId":10836,"journal":{"name":"Current Ophthalmology Reports","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2020-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s40135-020-00251-z","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43116237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
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