{"title":"Diving Deep into Deep Learning: An Update on Artificial Intelligence in Retina.","authors":"Brian E Goldhagen, Hasenin Al-Khersan","doi":"10.1007/s40135-020-00240-2","DOIUrl":"https://doi.org/10.1007/s40135-020-00240-2","url":null,"abstract":"<p><strong>Purpose of review: </strong>In the present article, we will provide an understanding and review of artificial intelligence in the subspecialty of retina and its potential applications within the specialty.</p><p><strong>Recent findings: </strong>Given the significant use of diagnostic imaging within retina, this subspecialty is a fitting area for the incorporation of artificial intelligence. Researchers have aimed at creating models to assist in the diagnosis and management of retinal disease as well as in the prediction of disease course and treatment response. Most of this work thus far has focused on diabetic retinopathy, age-related macular degeneration, and retinopathy of prematurity, although other retinal diseases have started to be explored as well.</p><p><strong>Summary: </strong>Artificial intelligence is well-suited to transform the practice of ophthalmology. A basic understanding of the technology is important for its effective implementation and growth.</p>","PeriodicalId":10836,"journal":{"name":"Current Ophthalmology Reports","volume":"8 3","pages":"121-128"},"PeriodicalIF":0.9,"publicationDate":"2020-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s40135-020-00240-2","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38736748","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Retinal Tamponades: Current Uses and Future Technologies.","authors":"Avnish Deobhakta, Richard Rosen","doi":"10.1007/s40135-020-00247-9","DOIUrl":"https://doi.org/10.1007/s40135-020-00247-9","url":null,"abstract":"<p><strong>Purpose of review: </strong>In this article, the current use and limitations of existing retinal tamponades are discussed. Potential novel developments that address those limitations are subsequently highlighted, along with areas of future improvements.</p><p><strong>Recent findings: </strong>While retinal tamponades have existed for decades and improved the treatment of retinal detachments, many problems still exist with their use, including inadequate tamponade of the inferior retina, toxicity from retained heavy liquids, glaucoma, and keratopathy, among others. New advancements in the components of heavy liquids and vitreous substitutes aim to mitigate those issues.</p><p><strong>Summary: </strong>Existing retinal tamponades, including perflurocarbon heavy liquids, fluorinated gases, and silicone oil, have specific limitations that cause potentially avoidable morbidity. New developments, such as heavy silicone oil, novel vitreous gels, and future avenues of approach, such as potentially reabsorbing heavy liquids may help increase our ability to treat retinal detachments with fewer complications.</p>","PeriodicalId":10836,"journal":{"name":"Current Ophthalmology Reports","volume":"8 3","pages":"144-151"},"PeriodicalIF":0.9,"publicationDate":"2020-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s40135-020-00247-9","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"25519521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Optical Coherence Tomography: Critical Tool to Manage Expectations after Cataract Extraction.","authors":"Raquel Goldhardt, Bradley Simon Rosen","doi":"10.1007/s40135-020-00243-z","DOIUrl":"https://doi.org/10.1007/s40135-020-00243-z","url":null,"abstract":"<p><strong>Purpose of review: </strong>To review evidence on the utility of spectral domain optical coherence tomography (SD-OCT) in evaluating retinal structure prior cataract surgery and highlight new technologies that can assess retinal function perioperatively.</p><p><strong>Findings: </strong>SD-OCT detected clinically unsuspected macular pathology in 4.6-25% of individuals in the pre-operative cataract evaluation. The most common findings were epiretinal membrane and macular degeneration with frequencies that varied by population studied. These conditions have been associated with complication after surgery (e.g. macular edema, visual dissatisfaction). As such, findings on SD-OCT may impact the informed consent process, alter IOL selection, and provide realistic postoperative vision expectations. Other technologies that assess retinal function, such as microperimetry and multifocal ERG are beginning to be studied but their utility in the pre-operative cataract evaluation is not yet known.</p><p><strong>Summary: </strong>SD-OCT should be incorporated as a routine test prior to surgery to manage patient expectations and assist with optimal IOL selection, as even individuals with a seemingly normal clinical exam may have macular pathology. SD-OCT is the most established method for evaluating retinal anatomy and offers the benefits of a reduction in cases with missed macular pathology and fewer postoperative visual surprises.</p>","PeriodicalId":10836,"journal":{"name":"Current Ophthalmology Reports","volume":"8 3","pages":"129-135"},"PeriodicalIF":0.9,"publicationDate":"2020-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s40135-020-00243-z","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"38526622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hayley Favre, S. Lahoti, Nasser G. Issa, Daniel A. Johnson, A. Kheirkhah
{"title":"Topical Steroids in Management of Dry Eye Disease","authors":"Hayley Favre, S. Lahoti, Nasser G. Issa, Daniel A. Johnson, A. Kheirkhah","doi":"10.1007/s40135-020-00249-7","DOIUrl":"https://doi.org/10.1007/s40135-020-00249-7","url":null,"abstract":"","PeriodicalId":10836,"journal":{"name":"Current Ophthalmology Reports","volume":"8 1","pages":"195 - 200"},"PeriodicalIF":0.9,"publicationDate":"2020-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s40135-020-00249-7","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47481803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Modern principles of the diabetic macular edema management","authors":"N. K. Mazurina, G. Stolyarenko","doi":"10.17816/OV33036","DOIUrl":"https://doi.org/10.17816/OV33036","url":null,"abstract":"Diabetes mellitus and diabetic retinal lesions are a global challenge for healthcare systems and one of the leading causes of severe vision loss among the working age population. Retinal laser coagulation remained the standard of therapy and the only possible treatment for diabetic macular edema (DME) in the 80-90s of the last century. The introduction of anti-VEGF therapy and glucocorticoids into the wide practice has significantly expanded the range of possibilities of DME treatment, allowing not only to stabilize patients vision, but also to improve it. The analyses of the large randomized clinical trials results are made and presented in this article, that highlight the basic principles of the contemporary DME treatment. This information is intended to help the ophthalmologist to develop the most optimal approach to treatment, considering the individual characteristics of each patient and the evidence-based efficacy and safety data of different methods.","PeriodicalId":10836,"journal":{"name":"Current Ophthalmology Reports","volume":"31 2 1","pages":""},"PeriodicalIF":0.9,"publicationDate":"2020-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90537334","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Emerging Technologies to Solve the Key Issues in Endothelial Keratoplasty","authors":"K. Brown, G. Dusting, M. Daniell","doi":"10.1007/s40135-020-00251-z","DOIUrl":"https://doi.org/10.1007/s40135-020-00251-z","url":null,"abstract":"","PeriodicalId":10836,"journal":{"name":"Current Ophthalmology Reports","volume":"8 1","pages":"236 - 244"},"PeriodicalIF":0.9,"publicationDate":"2020-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s40135-020-00251-z","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43116237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Svetlana S. Martirosyan, Diana R. Simonyan, Ilona K. Musheghyan, Mariam A. Ghazaryan
{"title":"Bilateral lacrimal gland enlargement as a clinical manifestation of sarcoidosis","authors":"Svetlana S. Martirosyan, Diana R. Simonyan, Ilona K. Musheghyan, Mariam A. Ghazaryan","doi":"10.17816/OV25854","DOIUrl":"https://doi.org/10.17816/OV25854","url":null,"abstract":"Sarcoidosis is an inflammatory disorder of unknown etiology. The main characteristics of sarcoidosis are non-caseating granulomas which can be formed in affected organs. Eye and its adnexal tissues can also be involved. In the early stages of sarcoidosis, the clinical picture may be mild and not always specific. Although the early signs of sarcoidosis are lung associated, we present a clinical case with diffuse enlargement of the lacrimal glands as a first sign of systemic sarcoidosis. A 21-years-old woman presented to the ophthalmological center with a 2-weeks history of having swollen, painful upper eyelids. Primary eye examination revealed palpable tender masses in the locations of the lacrimal glands. Characteristic for sarcoidosis X-ray findings and blood tests demanded lacrimal gland and lung biopsy for diagnosis verification. In spite sarcoidosis of lacrimal glands is a rare condition, it has to be taken into consideration in the differential diagnosis of lacrimal gland masses.","PeriodicalId":10836,"journal":{"name":"Current Ophthalmology Reports","volume":"39 1","pages":""},"PeriodicalIF":0.9,"publicationDate":"2020-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85761460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
O. Oganesyan, Оганесян Оганес Георгиевич, V. Getadaryan, Гетадарян Востан Рафаелович, P. M. Ashikova, Ашикова Патимат Магомедрасуловна, P. Makarov, Макаров Павел Васильевич, A. Khandzhyan, Ханджян Ануш Тиграновна
{"title":"Intrastromal descemet membrane transplantation in eyes with advanced keratoconus","authors":"O. Oganesyan, Оганесян Оганес Георгиевич, V. Getadaryan, Гетадарян Востан Рафаелович, P. M. Ashikova, Ашикова Патимат Магомедрасуловна, P. Makarov, Макаров Павел Васильевич, A. Khandzhyan, Ханджян Ануш Тиграновна","doi":"10.17816/OV20425","DOIUrl":"https://doi.org/10.17816/OV20425","url":null,"abstract":"Background. To report the outcomes of intrastromal Descemet membrane (DM) transplantation in corneas with advanced keratoconus. \u0000Materials and methods. Three eyes of 3 patients presented with advanced, progressive keratoconus. None of the eyes had prior UV-crosslinking or any other ocular surgery performed. All eyes had a donor DM implanted into a mid-stromal pocket under local anesthesia, and clinical outcomes were evaluated at 12 months after surgery. \u0000Results. To the best of our knowledge, this is the first report of DM transplantation performed in cases of advanced keratoconus. At 12 months after surgery, the DM graft was well positioned and barely visible within the recipient stroma, and all corneas were clear. None of the eyes showed signs of keratoconus progression throughout the follow-up period. No significant changes were observed in uncorrected (UCVA) and best contact lens corrected visual acuity (BCLCVA), central endothelial cell density (ECD), corneal thinnest point (CTP) pachymetry, and maximum keratometry values (SimK and Kmax). No early or late postoperative complications were observed. \u0000Conclusions. Intrastromal DM transplantation may potentially be an alternative to intrastromal Bowman layer transplantation in eyes with advanced keratoconus, to postpone deep anterior lamellar or penetrating keratoplasty.","PeriodicalId":10836,"journal":{"name":"Current Ophthalmology Reports","volume":"84 7 1","pages":""},"PeriodicalIF":0.9,"publicationDate":"2020-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89608322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
N. A. Sakhovskaya, M. Frolov, K. Kazakova, E. Belyaeva
{"title":"Complex clinical case of optic neuropathy differential diagnosis","authors":"N. A. Sakhovskaya, M. Frolov, K. Kazakova, E. Belyaeva","doi":"10.17816/OV19146","DOIUrl":"https://doi.org/10.17816/OV19146","url":null,"abstract":"The outcome of any damage or disease of the optic nerve is the atrophy of the optic nerve, which causes the irreversible loss of vision. The reasons of damage of the optic nerve are polymorphous, and early diagnosis allows to improve the efficacy of treatment and prevent irreversible consequences. The article presents a difficult clinical case of optic neuropathy differential diagnosis.","PeriodicalId":10836,"journal":{"name":"Current Ophthalmology Reports","volume":"4 1","pages":""},"PeriodicalIF":0.9,"publicationDate":"2020-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73015434","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
D. Davydov, Давыдов Дмитрий Викторович, Мagomed М. Маgomedov, Магомедов Магомед Маллаевич, Napisat М. Маgomedova, Магомедова Написат Магомедовна
{"title":"Conditions for improving the effectiveness of surgical treatment of patients with chronic dacryocystitis in endonasal endoscopic procedures","authors":"D. Davydov, Давыдов Дмитрий Викторович, Мagomed М. Маgomedov, Магомедов Магомед Маллаевич, Napisat М. Маgomedova, Магомедова Написат Магомедовна","doi":"10.17816/OV33437","DOIUrl":"https://doi.org/10.17816/OV33437","url":null,"abstract":"Introduction. Surgical treatment of patients with chronic dacryocystitis is a complex interdisciplinary problem. Lacrimal sac can be reached externally and internally (endonasally). The effectiveness of the treatment largely depends on the results of complete diagnosis and choice of a treatment method. \u0000Purpose. To analyze the effectiveness of surgical treatment of patients with chronic dacryocystitis in endonasal access. \u0000Materials and methods. The study of 225 patients consisted in the analysis of two groups of patients (20152019) with chronic dacryocystitis: the first group (110 patients) underwent an endonasal endoscopic dacryocystorhinostomy in the form of monooperation, the second underwent endonasal endoscopic dacryocystorhinostomy with additional intranasal interventions (115 patients). All patients underwent endoscopic examination of the nasal cavity and midface multispiral computed tomography (MSCT). \u0000Results. The results of the obtained data convincingly showed a higher efficiency of treatment in the group of patients with combined operations with the pathological processes revealed in intranasal localization in comparison with the group of monoperations. \u0000Conclusion. According to the study data, patients with chronic dacryocystitis should undergo full ophthalmologic and endonasal diagnostics, including multispiral computed tomography-dacryocystorhinography of the middle facial zone according to the described algorithm. When detecting pathological processes hindering the standard endonasal endoscopic dacryocystorhinostomy, it is necessary to perform an expanded scope of surgical interventions which will contribute to the efficiency of treatment of patients with chronic dacryocystitis up to 91.3%.","PeriodicalId":10836,"journal":{"name":"Current Ophthalmology Reports","volume":"35 1","pages":""},"PeriodicalIF":0.9,"publicationDate":"2020-08-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89801875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}