{"title":"Autoimmune Retinopathy, Testing, and Its Controversies","authors":"L. Roisman, J. Rossetto, R. Goldhardt","doi":"10.1007/s40135-021-00276-y","DOIUrl":"https://doi.org/10.1007/s40135-021-00276-y","url":null,"abstract":"","PeriodicalId":10836,"journal":{"name":"Current Ophthalmology Reports","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2021-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48841981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Michael J Gale, R. Kinast, F. Sanchez, S. Mansberger
{"title":"Adherence With Glaucoma Medications: Barriers to Success and Prospects for Improvement","authors":"Michael J Gale, R. Kinast, F. Sanchez, S. Mansberger","doi":"10.1007/s40135-021-00273-1","DOIUrl":"https://doi.org/10.1007/s40135-021-00273-1","url":null,"abstract":"","PeriodicalId":10836,"journal":{"name":"Current Ophthalmology Reports","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2021-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43924211","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"How Should Corneal Nerves be Incorporated Into the Diagnosis and Management of Dry Eye?","authors":"Sneh Patel, Divy Mehra, Kimberly Cabrera, Anat Galor","doi":"10.1007/s40135-021-00268-y","DOIUrl":"https://doi.org/10.1007/s40135-021-00268-y","url":null,"abstract":"<p><strong>Purpose: </strong>a)Confocal microscopy and aethesiometry have allowed clinicians to assess the structural and functional integrity of corneal nerves in health and disease. This review summarizes literature on nerves in dry eye disease (DED) and discusses how this data can be applied to DED diagnosis and treatment.</p><p><strong>Recent findings: </strong>b)Subjects with DED have a heterogenous symptom and sign profile along with variability in nerve structure and function. Most studies have reported lower nerve density and sensitivity in aqueous tear deficiency, while findings are more inconsistent for other DED subtypes. Examining nerve status, along with profiling symptoms and signs of disease, can help categorize subjects into disease phenotypes (structural and functional patterns) that exist under the umbrella of DED. This, in turn, can guide therapeutic decision-making.</p><p><strong>Summary: </strong>c)Due to the heterogeneity in symptoms and signs of DED, corneal nerve evaluations can be valuable for categorizing individuals into disease sub-types and for guiding clinical decision making.</p>","PeriodicalId":10836,"journal":{"name":"Current Ophthalmology Reports","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2021-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s40135-021-00268-y","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39827374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Current Indications for Photodynamic Therapy in Retina and Ocular Oncology","authors":"M. Di Nicola, B. Williams","doi":"10.1007/s40135-021-00272-2","DOIUrl":"https://doi.org/10.1007/s40135-021-00272-2","url":null,"abstract":"","PeriodicalId":10836,"journal":{"name":"Current Ophthalmology Reports","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2021-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42659218","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Comparison of Genomic Advances in Exfoliation Syndrome and Primary Open-Angle Glaucoma","authors":"J. H. Tran, L. Pasquale","doi":"10.1007/s40135-021-00270-4","DOIUrl":"https://doi.org/10.1007/s40135-021-00270-4","url":null,"abstract":"","PeriodicalId":10836,"journal":{"name":"Current Ophthalmology Reports","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2021-06-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s40135-021-00270-4","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43337283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Osmel P Alvarez, Anat Galor, Ghada AlBayyat, Carol L Karp
{"title":"Update on imaging modalities for ocular surface pathologies.","authors":"Osmel P Alvarez, Anat Galor, Ghada AlBayyat, Carol L Karp","doi":"10.1007/s40135-021-00265-1","DOIUrl":"10.1007/s40135-021-00265-1","url":null,"abstract":"<p><strong>Purpose of review: </strong>To discuss recent studies of imaging modalities for ocular surface pathologies.</p><p><strong>Recent findings: </strong>Novel micro-ocular coherence tomography technology can produce high-resolution images of corneal cellular and nervous structures. Ocular coherence tomography angiography can aid in detecting early stage limbal stem cell deficiency. Several studies used <i>in vivo</i> confocal microscopy to evaluate corneal nerve metrics and morphology.</p><p><strong>Summary: </strong>The applications of anterior segment optical coherence tomography, anterior segment optical coherence tomography angiography, ultrasound biomicroscopy, and <i>in vivo</i> confocal microscopy are useful technologies for imaging the ocular surface. Several studies have used artificial intelligence in combination with imaging technologies to create reliable and effective systems to detect and visualize ocular surface pathologies. AS OCT continues to be a key imaging tool and future development of μOCT technology may further enhance its utility.</p>","PeriodicalId":10836,"journal":{"name":"Current Ophthalmology Reports","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9455836/pdf/nihms-1787847.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"33461892","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Y. Kam, David A. Ramirez, Jennifer J. Ling, M. Greiner, Christopher S. Sáles
{"title":"Performing DMEK with Other Surgical Procedures: Staged vs. Combined Approaches in Straightforward Cases","authors":"Y. Kam, David A. Ramirez, Jennifer J. Ling, M. Greiner, Christopher S. Sáles","doi":"10.1007/s40135-021-00264-2","DOIUrl":"https://doi.org/10.1007/s40135-021-00264-2","url":null,"abstract":"","PeriodicalId":10836,"journal":{"name":"Current Ophthalmology Reports","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s40135-021-00264-2","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44002917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Intracranial Pressure and Its Relationship to Glaucoma","authors":"Brandon VanderZee, B. Shafer, John P Berdahl","doi":"10.1007/s40135-021-00267-z","DOIUrl":"https://doi.org/10.1007/s40135-021-00267-z","url":null,"abstract":"","PeriodicalId":10836,"journal":{"name":"Current Ophthalmology Reports","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2021-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s40135-021-00267-z","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43911171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Autologous Blood Products: When, Where, and How?","authors":"Arianna A. Tovar, Alfonso L. Sabater","doi":"10.1007/s40135-021-00266-0","DOIUrl":"https://doi.org/10.1007/s40135-021-00266-0","url":null,"abstract":"","PeriodicalId":10836,"journal":{"name":"Current Ophthalmology Reports","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2021-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s40135-021-00266-0","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49018439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Update on the Management of Ocular Surface Squamous Neoplasia.","authors":"Umangi Patel, Carol L Karp, Sander R Dubovy","doi":"10.1007/s40135-020-00260-y","DOIUrl":"https://doi.org/10.1007/s40135-020-00260-y","url":null,"abstract":"<p><strong>Purpose of review: </strong>To review and update the latest findings in diagnosis and management of ocular surface squamous neoplasia (OSSN).</p><p><strong>Recent findings: </strong>OSSN is the most common anterior segment neoplastic disease process. Several ocular surface imaging techniques have been developed for the early diagnosis and management of clinical and subclinical ocular surface squamous neoplasia, including high-resolution optical coherence tomography (HR-OCT), in vivo confocal microscopy, and ultrasound biomicroscopy. Treatment modalities include both surgical and medical management, with a recent trend towards primary and adjunctive pharmacotherapy.</p><p><strong>Summary: </strong>There is increasing use of HR-OCT for the diagnosis and monitoring of clinical and subclinical OSSN lesions. Topical pharmacotherapy agents, including interferon α-2b, 5-fluorouracil, and mitomycin C, have demonstrable efficacy in the treatment of OSSN and their use may be dictated based upon tumor factors, patient factors, cost, and side effect profile. Both surgical excision and adjunctive topical medications have excellent success, with the favored treatment method trending towards topical pharmacotherapy as primary therapy.</p>","PeriodicalId":10836,"journal":{"name":"Current Ophthalmology Reports","volume":null,"pages":null},"PeriodicalIF":0.9,"publicationDate":"2021-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s40135-020-00260-y","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39643657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}