Current issues in pharmacy and medicine: science and practice最新文献

{"title":"A study of preferences of instrumental cosmetology consumers","authors":"V. Demchenko, N. Tkachenko, N. Chervonenko, V. Demchenko","doi":"10.14739/2409-2932.2022.1.251215","DOIUrl":"https://doi.org/10.14739/2409-2932.2022.1.251215","url":null,"abstract":"A high demand for cosmetology among patients of various ages encourages the study of consumers’ needs and queries regarding instrumental cosmetology procedures.\u0000Aim of the work was to study the structure of consumers’ preferences of instrumental cosmetology procedures and to determine the factors of preferences in a group of young people for further use in the work of cosmetology facilities for shaping their marketing strategy.\u0000Materials and methods. Methods of information retrieval, synthesis, generalization, formalization, and questioning were used in the study. Research articles by domestic and foreign scientists regarding the instrumental procedures, the formation of consumer characteristic of cosmetology procedures, and the results of a consumer survey were used as the material for the study.\u0000Results. The consumers were surveyed using a specially designed online questionnaire, with the respondents’ consent and confidentiality compliance. 202 consumers of instrumental procedures took part in the survey. Respondents answered 11 questions regarding their attitude, awareness, trust and frequency of using various cosmetology procedures. A careful examination of the survey results revealed that in the “youth” group, a small part of the segment belongs to men, which encourages further research on reasoning, preferences, etc. of the male segment.\u0000Conclusions. The research enabled to study the structure of the consumers` preferences in instrumental cosmetology procedures and to determine the factors of their advantages in the study group. The priority information channels are the most trustworthy for the “youth” segment – social networks and communication with a cosmetologist. The results obtained are planned to be implemented in the work of cosmetology facilities to improve the quality of care and service.","PeriodicalId":10800,"journal":{"name":"Current issues in pharmacy and medicine: science and practice","volume":"24 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75316402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synthesis and study of the anticancer activity of some new 7H-[1,2,4]triazolo [3,4-b][1,3,4]thiadiazines","authors":"I. Myrko, T. Chaban, V. V. Ohurtsov, I. Drapak, V. Matiichuk","doi":"10.14739/2409-2932.2021.3.240361","DOIUrl":"https://doi.org/10.14739/2409-2932.2021.3.240361","url":null,"abstract":"The problem of finding effective low-toxic anticancer agents is one of the most important in modern medicine and pharmacy. Despite a large selection of anticancer drugs and a variety of mechanisms of their action, the effectiveness of existing drugs continues to be insufficient. Among the numerous natural and synthetic heterocyclic compounds that exhibit anticancer activity, 7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine derivatives, which are able to initiate different pathways of tumor cell death. Based on this, the synthesis of new derivatives of this class of compounds and the study of their anticancer properties is relevant.\u0000The aim of the work is to synthesis of new 7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazines and study their anticancer activity.\u0000Materials and methods. It was used methods of organic synthesis, physical and chemical methods of analysis organic compounds (1H NMR spectroscopy, elemental analysis).\u0000Results. In order to obtain new 7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazines, the interaction implemented of 4-amino-4H-[1,2,4]triazole-3-thiols with the corresponding bromoacetophenones. The reaction proceeds by heating the above reagents in alcohol with the closure of the thiadiazine ring and the formation of 7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine systems. The structure of all synthesized compounds was confirmed by 1H NMR spectroscopy and elemental analysis data.\u0000The study of the anticancer activity of the synthesized compounds was carried out in the framework of the international scientific program DTP (Developmental Therapeutics Program) of the National Cancer Institute (NCI, Bethesda, Maryland, USA). It was found that the synthesized compounds exhibited different levels of anticancer activity. The most active among the tested substances was compound 3j with an average GP value of 28.73. The most sensitive to it were the lines of melanoma MDA-MB-435 and SK-MEL-2, kidney cancer A498 and RXF 393, CNS cancer SNB-75, and non-small cell lung cancer NCI-H522. The secondary stage of studies of this compound confirmed its high anticancer activity against most cancer cell lines.\u0000Conclusions. As a result of the interaction of 4-amino-4H-[1,2,4]triazole-3-thiols with the relevant bromoacetophenones, a series of new triazolo[3,4-b][1,3,4]thiadiazines was not described in the literature was synthesized. Testing the synthesized compounds for the antitumor activity made it possible to isolate 1 highly active compound with a pronounced anticancer effect, which in terms of activity approaches or exceeds the known drugs 5-fluorouracil (5-FU) and cisplatin, as well as an anticancer agent, curcumin.\u0000 ","PeriodicalId":10800,"journal":{"name":"Current issues in pharmacy and medicine: science and practice","volume":"32 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74618208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative chromato-mass spectrometric study of tinctures based on Echinacea purpurea (L.) Moench","authors":"Y. I. Kornievskiy, D. Skoryna, V. H. Korniievska, N. V. Kandybei","doi":"10.14739/2409-2932.2021.3.242845","DOIUrl":"https://doi.org/10.14739/2409-2932.2021.3.242845","url":null,"abstract":"An urgent problem today is the spread of secondary immunodeficiencies associated with increased stress, urbanization, and negative changes in the environment that lead to impaired immune function. Herbal remedies are milder, less likely to become addictive and have side effects, and are long-lasting. A promising plant with immunomodulatory action is Echinacea purpurea (L.) Moench, a member of the family Asteraceae. The main active ingredients of echinacea are phenolic compounds, carbohydrates, and alkylamides. The chemical composition of echinacea is also represented by flavonoids, tannins, saponins, higher fatty acids, amino acids, betaine, essential oil, macro- and microelements (Se, Co, Ag, Mo, Zn, Mg, K, Na, Fe, etc.). Drugs have immunostimulatory, antioxidant, membrane-stabilizing effect, promote healing of wounds, burns, ulcers, are used in infectious and viral diseases, especially HF. They are traditionally used for furunculosis, septicemia (infection of the blood), pyorrhea, tonsillitis, especially for the treatment of boils, carbuncles, and abscesses. It is also important that in modern pharmaceutical science the leading place is occupied by research related to the introduction into medical practice of herbal medicines, the study of their chemical composition, standardization, development of optimal technologies for the manufacture of phytopreparations. That is why the objects of our research were tinctures based on Echinacea purpurea.\u0000The aim of the work is to study and compare the component composition of tinctures based on Echinacea purpurea (L.) Moench using gas chromatography (GC).\u0000Materials and methods. Tinctures of rhizomes with roots of Echinacea purpurea were used for the study: experimental – made according to industrial technological recipe (1:5, extractant – ethanol 70 %) from raw materials harvested in July 2019 at the research site of Zaporizhzhia State Medical University and control – finished products LLC “Zhytomyr Pharmaceutical Factory”, series 20319. Tinctures were investigated on a gas chromatograph Agilent 7890B with mass spectrometric detector 5977B. The NIST14 mass spectrum library was used to identify the components.\u0000Results. 31 (experimental) and 23 (control) components were identified by GC in rhizomes with rhizomes of Echinacea purpurea. The results of the study indicate that the qualitative and quantitative chemical composition of rhizomes with roots of Echinacea purpurea was characterized by complexity and variability. This fact complicates the process of standardization of phytopreparations and can affect their effectiveness and safety. Therefore, members of the genus Echinacea should be the subject of further in-depth chemical study.\u0000Conclusions. A comparative analysis of the component composition of tinctures based on Echinacea purpurea (L.) Moench was studied and performed with the help of GC. The GC method is suitable for the determination of natural BAS in the composition of phytopreparations from echin","PeriodicalId":10800,"journal":{"name":"Current issues in pharmacy and medicine: science and practice","volume":"13 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75357644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pharmacoeconomic analysis of drug supply of the military personnel with chronic bronchitis","authors":"O. V. Plieshkova, O. Bielozorova, M. Bilous, D. Drozdov, A. Nikituk","doi":"10.14739/2409-2932.2021.3.241270","DOIUrl":"https://doi.org/10.14739/2409-2932.2021.3.241270","url":null,"abstract":"Despite the superiority of bronchitis in the structure of respiratory diseases in the military personnel, its course develops with certain peculiarities due to the peculiarities of military service. Consequently, the optimization of the costs of providing the military personnel with medicines is becoming more and more of medical and social importance. Reasonable selection of medicines in the treatment of chronic bronchitis is the result of the choice of effective and safe drugs, considering the cost of the components for military health care.\u0000Aim. To perform a pharmacoeconomic analysis of drug supply to the military personnel with chronic bronchitis.\u0000Materials and methods. The materials of the study were a database of drugs registered in Ukraine, presented on the official website of the State Institution “State Expert Center” of the Ministry of Health of Ukraine. The study employed “cost – effectiveness” method, which allows comparing the cost of a particular treatment method and its effectiveness.\u0000Results. The scheme of the pharmacoeconomic analysis method has been offered. According to the results of the previously formed list of drugs for the treatment of military personnel with chronic bronchitis, a further analysis of the proposed range of drugs is conducted using an expert survey. By calculating the efficacy ratio within each presented pharmacotherapeutic group, a 10-item list of the most optimal drugs for the treatment of chronic bronchitis has been compiled.\u0000Conclusions. Pharmacoeconomic analysis of medical supply to the military personnel is a constructive solution in the process of identifying manufacturers as potential suppliers of medicines to cover the needs of the medical service of the Armed Forces of Ukraine. Based on the results of the pharmacoeconomic analysis of the drug supply to military personnel with chronic bronchitis, a recommended list of drugs for their treatment has been formed. However, this list can be expanded to include drugs with the highest efficacy – according to the expert assessment. In the future it may become the basis for inclusion of drugs in the clinical protocols of medical care and could be used for the development of cost standards for the relevant nosological forms, which will improve the efficiency and quality of treatment and will provide economic benefits.","PeriodicalId":10800,"journal":{"name":"Current issues in pharmacy and medicine: science and practice","volume":"47 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81275343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Parameters of obtaining tincture from underground organs of Sanguisorba officinalisand study its biological activity","authors":"T. Oproshanska, O. Khvorost","doi":"10.14739/2409-2932.2021.3.244230","DOIUrl":"https://doi.org/10.14739/2409-2932.2021.3.244230","url":null,"abstract":"The aim of the work is to experimentally determine the optimal parameters for obtaining a tincture of rhizomes with roots of Sanguisorba officinalis and to investigate its antimicrobial and antioxidant activity.\u0000Materials and methods. Rhizomes with roots of Sanguisorba officinalis were harvested in autumn 2019. When establishing the optimal parameters of the technology of obtaining tincture, the evaluation criterion was the number of the sum of polyphenols and the amount of hydroxycinnamic acids, which were determined by spectrophotometric method according to the methods of the State Pharmacopoeia of Ukraine 2.0. Antimicrobial activity was studied by agar diffusion and serial dilutions, antioxidant – in vitro using a stable radical 2,2-diphenyl-1-picrylhydrazyl (2,2-diphenyl-1-picrylhydrazyl – DPPH).\u0000Results. The optimal parameters for obtaining a tincture of rhizomes with roots of Sanguisorba officinalis was extraction method maceration at room temperature, raw material-finished product ratio 1:5, time 48 hours, extractant 50 % ethyl alcohol, the number of polyphenols, and the number of hydroxycinnamic acids in terms of dry raw materials not less than 4.0 % and 1.5 % respectively. The resulting tincture exhibits antimicrobial activity against microorganisms Bacillus subtilis ATCC 6633 (growth retardation 26.40 ± 1.04 mm), Staphylococcus aureus ATCC 25923 (growth retardation 24.60 ± 0.68 mm) and Pseudomonas aeruginosa ATCС 27853 (growth retardation 23.60 ± 0.68 mm) and at a dose of 0.02 ml showed antioxidant activity at the level of 70 %.\u0000Conclusions. The parameters of obtaining a tincture of rhizomes with roots of Sanguisorba officinalis were determined and its antimicrobial and antioxidant activity was studied.","PeriodicalId":10800,"journal":{"name":"Current issues in pharmacy and medicine: science and practice","volume":"76 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87050108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The experience, results, and possible perspectives of organizing the optimally accessible primary medical care for the rural population of Zaporizhzhia region","authors":"O. H. Aleksieiev, V. Taranov, V. P. Petrykhin","doi":"10.14739/2409-2932.2021.3.241818","DOIUrl":"https://doi.org/10.14739/2409-2932.2021.3.241818","url":null,"abstract":"Nowadays, the assessment of the activity of the domestic healthcare system is an important and actual issue, especially against the background the active reformation of this industry. One of the important elements of the assessment is studying the availability of primary healthcare to the rural population.\u0000The aim of this work is to study the territorial accessibility of primary healthcare, the adequacy and effectiveness of the principles of forming a network of primary care facilities in the rural areas of Zaporizhzhia region that enables to address issues and optimize the location of primary care facilities in the rural areas.\u0000Materials and methods. The materials of the research were the data of the official statistical reports for the past 20 years, which characterize the state of health and the degree of medical care accessibility to the rural population. During the research, the technique of complex social and hygienic research was applied, with the use of historical, sociological, sanitary and statistical methods, organizational experiment and others.\u0000Results. The article presents the main results of studying the current state of primary healthcare organization for the rural population of Zaporіzhzhia region against the background of active reforming processes. According to the research results, the main elements forming the system of accessibility are territorial, medical, social and economic. The main factors of impact on territorial accessibility are identified. These are: the nature of the settlement of rural residents (density, compactness, service-area radius, the proportion of the rural population, the distance between villages, the distance from a household to a healthcare facility); quality of roads; transport connections between settlements and healthcare facilities; availability of communication means.\u0000Conclusions. As a result of the research, the following conclusions were drawn. Such factors as population density, compactness of its location, service-area radius, distance between villages, distance from a household to a healthcare facility, condition and quality of roads, transport connections between settlements and healthcare facilities are important during forming or improving the network of healthcare facilities in rural areas. These factors must be considered for the rational placement of primary care facilities in rural areas.\u0000 ","PeriodicalId":10800,"journal":{"name":"Current issues in pharmacy and medicine: science and practice","volume":"70 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76126074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Formation of the demand for contraceptives using the Van Westendorp method based on establishing consumer value","authors":"підставі встановлення, споживчої цінності, T. Mahanova","doi":"10.14739/2409-2932.2021.3.239753","DOIUrl":"https://doi.org/10.14739/2409-2932.2021.3.239753","url":null,"abstract":"One of the main indicators of the consumer value of a product is the price. Its controversial idealistic and materialistic basis is aimed at securing the interests of two opposites: producer-seller and buyer. Correctly made pricing decisions, taking into account the requirements of both players in the pharmaceutical market, will effectively regulate the processes of the pharmaceutical business and the supply system.\u0000The aim: approbation of the Van Westendorp method on the example of contraceptives; establishing their consumer value for further rational decision-making regarding the improvement of the system for providing contraceptives to Ukrainian female consumers.\u0000Materials and methods. The research used the marketing Van Westendorp method based on surveying a quota sample of women of reproductive age from one of the Ukrainian regions. The main calculations were performed with MS Excel 2010 software.\u0000Results. The survey of 420 women enabled to set the maximum range of readiness to pay (the point of maximum cheapness and high cost) for the most advanced pharmaceutical types of contraception (hormonal, non-hormonal and medical products) in the age and income quotas. It was established that the price sensitivity depends on social and economic indicators.\u0000Conclusions. The established maximal ranges of willingness to pay are well below market prices for contraceptives. The exception is cheap and widespread contraception (aerosol and male condom), which confirms the need to use marketing research methods to meet the needs of the female consumer.","PeriodicalId":10800,"journal":{"name":"Current issues in pharmacy and medicine: science and practice","volume":"27 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75250246","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Means of occupational therapy in (individual) rehabilitation programs for people with Parkinson’s disease","authors":"O. Antonova, S. Sorokina","doi":"10.14739/2409-2932.2021.3.239791","DOIUrl":"https://doi.org/10.14739/2409-2932.2021.3.239791","url":null,"abstract":"The aim of the work is to develop a set of rehabilitation measures including occupational therapy classes for Parkinson’s disease and to assess the objective condition of patients on the scales of non-motor symptoms, cognitive and mental disorders.\u0000Materials and methods. The study of patients was conducted on the basis of anamnesis, objective examination and scales for assessment of non-motor symptoms, cognitive and mental disorders (scale of non-motor symptoms – NMSS, scale of mental disorders – MMSE, Montreal scale of cognitive disorders – MOCA); to assess non-motor symptoms, a patient questionnaire was additionally used to identify autonomic disorders (according to A. M. Wayne, 1998). The control and experimental groups were offered exercise, physiotherapy, massage and nutrition (diet). Occupational therapy was added for the experimental group.\u0000Results. After the physical rehabilitation, the condition of the patients significantly improved. The final score in the experimental group of patients with non-motor manifestations of Parkinson’s disease on the scale of assessment of non-motor symptoms was statistically significantly lower and was 61.04 ± 0.39 (P < 0.01). The final score on the scale of mental disorders was statistically significantly higher – 27.78 ± 0.27 (P < 0.01), on the scale of cognitive changes, it also became statistically significantly higher – 25.13 ± 0.19 (P < 0.01). According to A. M. Wayne’s questionnaire of autonomic disorders, the total score in the control group was 64.0 ± 3.2. In the experimental group of patients, the total score was 51.0 ± 5.4 points (P < 0.01). Thus, under the influence of additional occupational therapy classes, in the experimental group both on the scale of non-motor symptoms and by A. M. Wayne’s, questionnaire there was a statistically significant improvement in the condition of patients.\u0000Conclusions. Based on the results of the study, it can be concluded that there is a significant difference (P < 0.01) in the condition of patients on the final scores, with the pronounced improvement in the condition of the experimental group patients in comparison with the control group patients, following the results of all survey scales. A significant difference is observed on the scale of non-motor symptoms. A certain role in improving the condition of patients with appropriate screening using study scales and a patient questionnaire to identify autonomic disorders (according to A. M. Wayne, 1998), apparently played a component of the rehabilitation program, which further included occupational therapy classes.","PeriodicalId":10800,"journal":{"name":"Current issues in pharmacy and medicine: science and practice","volume":"132 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80150842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Study of flavonoids and phenolic acids in green tea leaves","authors":"O. Maslov, S. Kolisnyk, M. Komisarenko, E. Akhmedov, S. M. Poluian, Z. Shovkova","doi":"10.14739/2409-2932.2021.3.240287","DOIUrl":"https://doi.org/10.14739/2409-2932.2021.3.240287","url":null,"abstract":"The aim of work is study qualitative composition and quantitative content of flavonoids and phenolic acids in green tea leaves.\u0000Material and methods. The object of the study was green tea leaves, which were collected in Anhui Province, China. The analysis of 60  % ethanolic extract from green tea leaves was performed by high-performance liquid chromatography using a Prominence LC-20 Shimadzu chromatographic system (Japan) with an SPD-20AV spectrophotometric detector, an Agilent Technologies Microsorb-MV-150 column (reversed-phase, C18 modified silica gel, length – 250 mm, diameter – 4.6 mm, particles size – 5 μm). Identification of substances in the extract was carried out by comparing the retention time and the spectral characteristics of the test substances with the same characteristics of the reference standards.\u0000Results. 13 compounds were identified and determined by high-performance liquid chromatography. Among flavonoid aglycones quantitatively dominated by quercetin (0.35 %), in the case of flavonoid glycosides, it was luteolin-6-C-glycoside (1.30 %) and among phenolic acids, it was gallic acid (5.21 %).\u0000Conclusions. The qualitative composition, quantitative content of flavonoids and phenolic acids in the green tea leaves were determined by high-performance liquid chromatography. According to HPLC, the content of flavonoids in green tea leaves was higher than the content of phenolic acids.","PeriodicalId":10800,"journal":{"name":"Current issues in pharmacy and medicine: science and practice","volume":"45 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82356102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dynamics of general physical fitness indicators in the system of physical therapy of 11–13-year-old women weightlifters after traumatic injuries of the musculoskeletal system","authors":"E. Doroshenko, A. A. Orlov, O. Chernenko, A. Hurieieva, I. Shapovalova, V. I. Hlukhykh, S. Polskyi, I. Sazanova, M. M. Syromiatnykov","doi":"10.14739/2409-2932.2021.3.234033","DOIUrl":"https://doi.org/10.14739/2409-2932.2021.3.234033","url":null,"abstract":"The aim of the work to determine the dynamic characteristics of overall physical condition indicators in 11–13-year-old female weightlifters after injuries of the musculoskeletal system at the training stage of physical therapy.\u0000Materials and methods. The experimental population comprised 45 female weightlifters (aged 11–13 years, qualification ‒ I, II, III junior categories) from SСYSSOR “Spartak” of the Zaporizhzhia regional council, CYSS “Kolos” of Kamiansko-Dniprovskyi district of Zaporizhzhia region, Berdiansk CYSS of Zaporizhzhia Region City Council, and students of Kharkiv Regional Higher School of Physical Culture and Sports majoring in weightlifting. Patients after musculoskeletal injuries were divided into two groups: main (MG, n = 22) and control (CG, n = 23). Patients of the control group underwent standard treatment (generally prescribed in medical establishments). For main group patients in the training period, the program of physical therapy has been developed and implemented, with the current control of overall physical condition indicators.\u0000Research methods. Analysis of literature and sources of information presented on the Internet; clinical observations; pedagogical testing; methods of mathematical statistics.\u0000Results. Analysis of overall physical condition indicators of athletes of 11–13-year-old weightlifters of the main and control groups during the recovery and training periods allows us to state that main group athletes have higher growth rates, and dynamic characteristics of their overall physical condition are linear with constant focus on improvement. According to the indicators of “running 30 m, s” test, the following growth indicators were recorded: main group athletes (-0.48), control group athletes (-0.29), the difference (-0.19). According to the indicators of “standing long jump, cm” test, the following growth indicators were recorded: main group athletes (+14), control group athletes (+5), difference (+9). According to the results of the test “flexion-extension of the arms in the supine position, n” the following indicators were obtained: main group athletes (+4.44), control group athletes (+2.86), difference (+1.58).\u0000Conclusions. Intensification of the training process and forcing the training of junior athletes in weightlifting are the leading factors that result in injuries of the musculoskeletal system, multisystem pathologies and the development of pathomorphic phenomena. Indicators of overall physical condition of weightlifters aged 11–13 allow us to state that main group athletes have a higher difference in growth, and the tendency of their overall physical condition has a linear focus on improvement. Indicators of overall physical condition of control group athletes are nonlinear, according to “running 30 m, s” and “standing long jump, cm” the test results.","PeriodicalId":10800,"journal":{"name":"Current issues in pharmacy and medicine: science and practice","volume":"21 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-10-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78917766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}