Current Gastroenterology Reports最新文献_第5页

Persistent Ostomy Following Percutaneous Endoscopic Gastrostomy Removal: Treatment Strategies. 经皮内镜胃造口术后持续造口：治疗策略。

Current Gastroenterology Reports Pub Date : 2024-02-01 Epub Date: 2024-01-09 DOI: 10.1007/s11894-023-00912-6

Alsiddig Elmahdi, Mohamed Eisa, Robert Martindale, Endashaw Omer

{"title":"Persistent Ostomy Following Percutaneous Endoscopic Gastrostomy Removal: Treatment Strategies.","authors":"Alsiddig Elmahdi, Mohamed Eisa, Robert Martindale, Endashaw Omer","doi":"10.1007/s11894-023-00912-6","DOIUrl":"10.1007/s11894-023-00912-6","url":null,"abstract":"Purpose of review: The purpose of this article is to review available literature on management of persistent ostomy following PEG tube removal. We will discuss the incidence of persistent gastrocutaneous fistula (GCF) following PEG tube removal, risk factors for their development, and management strategies that have been proposed and their efficacy.Recent findings: The use of over the scope clips (OTSC) have evolved recently in the management of gastrointestinal bleeding, perforation, and fistula closures. OTSC has become more readily available and proven to be effective and safe. Suturing devices have shown promising results. Persistent gastrocutaneous fistula following PEG removal is a rare yet serious complication that can lead to continuous skin irritation and leakage of gastric contents and acid. There are several postulated risk factors but the most important of these is duration of placement. Management can include medical therapy which has recently been shown to be somewhat effective, endoscopic therapy and surgery as a last resort. Overall, the data on GCFs is limited and further study with larger sample size is needed.","PeriodicalId":10776,"journal":{"name":"Current Gastroenterology Reports","volume":" ","pages":"53-56"},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139402140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical Application of Intestinal Ultrasound in Inflammatory Bowel Disease. 肠道超声在炎症性肠病中的临床应用。

Current Gastroenterology Reports Pub Date : 2024-02-01 Epub Date: 2024-01-20 DOI: 10.1007/s11894-024-00915-x

Noa Krugliak Cleveland, Joëlle St-Pierre, Amelia Kellar, David T Rubin

{"title":"Clinical Application of Intestinal Ultrasound in Inflammatory Bowel Disease.","authors":"Noa Krugliak Cleveland, Joëlle St-Pierre, Amelia Kellar, David T Rubin","doi":"10.1007/s11894-024-00915-x","DOIUrl":"10.1007/s11894-024-00915-x","url":null,"abstract":"Purpose of review: Intestinal ultrasound (IUS) is a non-invasive, accurate, and well-tolerated tool that provides real-time assessment of inflammatory bowel disease (IBD) activity and is therefore an ideal monitoring tool. This review describes the evolving role of IUS in each phase of clinical management of IBD.Recent findings: Accumulating evidence has demonstrated that IUS is an excellent tool for the assessment of suspected IBD, with a very high negative predictive value. It accurately assesses disease activity, disease complications, and in the pre-treatment phase, provides a benchmark for subsequent follow-up. IUS can detect early therapeutic response and correlates well with other established monitoring modalities with arguably superior predictive capabilities and ability to assess a deeper degree of remission, transmural healing (TH). IUS has a crucial role in the management of IBD and has ushered in a new era of monitoring with more rapid evaluation and the opportunity for early optimization, deeper therapeutic targets, and improved outcomes.","PeriodicalId":10776,"journal":{"name":"Current Gastroenterology Reports","volume":" ","pages":"31-40"},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11025373/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139502364","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Getting the BS out of Irritable Bowel Syndrome with Diarrhea (IBS-D): Let's Make a Diagnosis. 摆脱肠易激综合征伴腹泻 (IBS-D) 的困扰：让我们来做个诊断。

Current Gastroenterology Reports Pub Date : 2024-01-01 Epub Date: 2023-12-30 DOI: 10.1007/s11894-023-00909-1

Christine L Frissora, Lawrence R Schiller

引用次数: 0

Managing IBD Patients with Concomitant HIV Infection - a Systematic Review. 管理合并 HIV 感染的 IBD 患者 - 系统综述。

Current Gastroenterology Reports Pub Date : 2024-01-01 Epub Date: 2024-01-05 DOI: 10.1007/s11894-023-00914-4

Hugo Sousa, Joana Barroso, Raquel Tavares, Joana Torres

{"title":"Managing IBD Patients with Concomitant HIV Infection - a Systematic Review.","authors":"Hugo Sousa, Joana Barroso, Raquel Tavares, Joana Torres","doi":"10.1007/s11894-023-00914-4","DOIUrl":"10.1007/s11894-023-00914-4","url":null,"abstract":"Purpose of review: Inflammatory Bowel Disease (IBD) is a chronic GI inflammatory condition induced by a dysregulated immune system activation, whereas HIV infection causes depletion of the immune system, inducing immunosuppression. Given the increasing incidence of IBD across the globe, including in developing countries, the co-prevalence of both conditions is expected to increase. Herein, we systematically review the data describing disease course when both pathologies co-exist.Recent findings: Overall, the co-prevalence of IBD and HIV is around 0.1 to 2%. While IBD does not seem to affect HIV course, the opposite is controversial, as some studies report milder IBD phenotype, with fewer disease relapses especially when CD4 + counts are lower than 200 cells/µL. Despite growing evidence to support the safety of the use of immunosuppressants and biologics in IBD-HIV infected patients, these classes of drugs are used in less than 50% of patients, as compared to non-HIV infected IBD patients. There is a need for more studies on disease course and safety of IBD medications in the setting of IBD.","PeriodicalId":10776,"journal":{"name":"Current Gastroenterology Reports","volume":" ","pages":"1-8"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139097527","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Neurogastroenterology and Motility Disorders of the Gastrointestinal Tract in Cystic Fibrosis. 神经胃肠病学和胃肠运动障碍的囊性纤维化。

Current Gastroenterology Reports Pub Date : 2024-01-01 Epub Date: 2023-12-07 DOI: 10.1007/s11894-023-00906-4

Dhiren Patel, Folashade Jose, Jason Baker, Baha Moshiree

{"title":"Neurogastroenterology and Motility Disorders of the Gastrointestinal Tract in Cystic Fibrosis.","authors":"Dhiren Patel, Folashade Jose, Jason Baker, Baha Moshiree","doi":"10.1007/s11894-023-00906-4","DOIUrl":"10.1007/s11894-023-00906-4","url":null,"abstract":"Purpose of review: To discuss all the various motility disorders impacting people with Cystic Fibrosis (PwCF) and provide diagnostic and management approaches from a group of pediatric and adult CF and motility experts and physiologists with experience in the management of this disease.Recent findings: Gastrointestinal (GI) symptoms coexist with pulmonary symptoms in PwCF regardless of age and sex. The GI manifestations include gastroesophageal reflux disease, esophageal dysmotility gastroparesis, small bowel dysmotility, small intestinal bacterial overgrowth syndrome, distal idiopathic obstruction syndrome, constipation, and pelvic floor disorders. They are quite debilitating, limiting the patients' quality of life and affecting their nutrition and ability to socialize. This genetic disorder affects many organ systems and is chronic, potentially impacting fertility and future family planning, requiring a multidisciplinary approach. Our review discusses the treatments of motility disorders in CF, their prevalence and pathophysiology. We have provided a framework for clinicians who care for these patients that can help to guide their clinical management.","PeriodicalId":10776,"journal":{"name":"Current Gastroenterology Reports","volume":" ","pages":"9-19"},"PeriodicalIF":0.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138498022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

ARFID at 10 years: A Review of Medical, Nutritional and Psychological Evaluation and Management. ARFID 10年：医学、营养和心理评估与管理综述。

Current Gastroenterology Reports Pub Date : 2023-12-01 Epub Date: 2023-09-27 DOI: 10.1007/s11894-023-00900-w

Martin Fisher, Jacqueline Zimmerman, Caroline Bucher, Lauren Yadlosky

{"title":"ARFID at 10 years: A Review of Medical, Nutritional and Psychological Evaluation and Management.","authors":"Martin Fisher, Jacqueline Zimmerman, Caroline Bucher, Lauren Yadlosky","doi":"10.1007/s11894-023-00900-w","DOIUrl":"10.1007/s11894-023-00900-w","url":null,"abstract":"Purpose of review: Avoidant restrictive food intake disorder (ARFID) is a diagnostic term that was established 10 years ago to describe those patients with an eating disorder, mostly children and adolescents, who have poor nutrition that is not due to body image or weight concerns. This article reviews the diagnosis and subtypes of ARFID, as well as the medical, nutritional and psychological principles of evaluation and management of the disorder.Recent findings: In the past 10 years, clinicians have refined their approaches to managing the two major subtypes of ARFID: (1) those patients with a longer-term restriction in the amount and/or variety of the foods they eat, and (2) those patients with a shorter-term decrease in eating because of fear of aversive consequences such as vomiting, choking, GI symptoms or an allergic reaction to food. In that same time, the field of psychology has been developing evidence-based approaches to management of ARFID in each of its manifestations. Each patient with ARFID presents with a unique set of medical, nutritional and psychological factors that requires an individualized and multi-disciplinary approach in the management of this difficult to treat disorder.","PeriodicalId":10776,"journal":{"name":"Current Gastroenterology Reports","volume":" ","pages":"421-429"},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41143251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Esophageal Radiography Interpretation: a Primer for the Gastroenterologist. 食道放射学解读：胃肠科医生的入门知识。

Current Gastroenterology Reports Pub Date : 2023-12-01 Epub Date: 2023-11-08 DOI: 10.1007/s11894-023-00903-7

Catiele Antunes, Joshua A Sloan

{"title":"Esophageal Radiography Interpretation: a Primer for the Gastroenterologist.","authors":"Catiele Antunes, Joshua A Sloan","doi":"10.1007/s11894-023-00903-7","DOIUrl":"10.1007/s11894-023-00903-7","url":null,"abstract":"Purpose of review: Radiological studies can be helpful when evaluating patients with suspect esophageal disorders. From benign strictures to malignancy and motility disorders such as achalasia, imaging modalities play a significant role in diagnosis. This review explores the role of different imaging modalities in the most frequently encountered esophageal pathologies.Recent findings: Conventional barium esophagram has long been considered the primary imaging modality of the esophagus. In the same fashion, a timed barium esophagram is a valuable tool in the evaluation of achalasia and esophagogastric junction outlet obstruction. Over the last few decades there has been an increase in CT and MRI studies, which also play a role in the evaluation of esophageal pathologies. However, not infrequently, these newer imaging techniques can result in incidental esophageal findings. It is important that gastroenterologists appreciate the value of different modalities and recognize key imaging features. The diagnosis and management of esophageal disorders is evolving. A basic understanding of esophageal radiology is essential to any gastroenterologist caring for patients with esophageal complaints.","PeriodicalId":10776,"journal":{"name":"Current Gastroenterology Reports","volume":" ","pages":"363-373"},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71479102","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Revisiting Proton Pump Inhibitors as Chemoprophylaxis Against the Progression of Barrett's Esophagus. 质子泵抑制剂作为预防Barrett食管进展的化学药物的再研究。

Current Gastroenterology Reports Pub Date : 2023-12-01 Epub Date: 2023-11-09 DOI: 10.1007/s11894-023-00905-5

Shawn L Shah, Kerry Dunbar

引用次数: 0

Hepatitis D Virus and HBsAg Dynamics in the era of new Antiviral Treatments. 新抗病毒治疗时代的丁型肝炎病毒和HBsAg动态。

Current Gastroenterology Reports Pub Date : 2023-12-01 Epub Date: 2023-10-11 DOI: 10.1007/s11894-023-00901-9

Louis Shekhtman, Sarah Duehren, Ohad Etzion, Scott J Cotler, Harel Dahari

{"title":"Hepatitis D Virus and HBsAg Dynamics in the era of new Antiviral Treatments.","authors":"Louis Shekhtman, Sarah Duehren, Ohad Etzion, Scott J Cotler, Harel Dahari","doi":"10.1007/s11894-023-00901-9","DOIUrl":"10.1007/s11894-023-00901-9","url":null,"abstract":"Purpose of review: Hepatitis D virus (HDV) infection is the most severe form of chronic viral hepatitis, with no FDA-approved therapy. Progress in the development of effective HDV treatments is accelerating. This review highlights how mathematical modeling is improving understanding of HDV-HBsAg-host dynamics during antiviral therapy and generating insights into the efficacy and modes of action (MOA) of new antiviral agents.Recent findings: Clinical trials with pegylated-interferon-λ, bulevertide, nucleic acid polymers, and/or lonafarnib against various steps of the HDV-life cycle have revealed new viral-kinetic patterns that were not observed under standard treatment with pegylated-interferon-α. Modeling indicated that the half-lives of circulating HDV and HBsAg are ~ 1.7 d and ~ 1.3 d, respectively, estimated the relative response of HDV and HBsAg during different antiviral therapies, and provided insights into the efficacy and MOA of drugs in development for treating HDV, which can inform response-guided therapy to individualize treatment duration. Mathematical modeling of HDV and HBsAg kinetics provides a window into the HDV virus lifecycle, HDV-HBsAg-host dynamics during antiviral therapy, and the MOA of new drugs for HDV.","PeriodicalId":10776,"journal":{"name":"Current Gastroenterology Reports","volume":" ","pages":"401-412"},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10842234/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41194139","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Modern-Day Practice of DCD Liver Transplantation: Controversies, Innovations, and Future Directions. DCD肝移植的现代实践：争议、创新和未来方向。

Current Gastroenterology Reports Pub Date : 2023-12-01 Epub Date: 2023-10-28 DOI: 10.1007/s11894-023-00902-8

Omar J Haque, Eve M Roth, David D Lee

引用次数: 0