Current Environmental Health Reports最新文献

{"title":"Environmental Exposures and Neuroimaging in Children with Neurodevelopmental Disorders: A Scoping Review.","authors":"Elza Rechtman, Vida Rebello, Azzurra Invernizzi, Anna Sather, Kristie Oluyemi, Michelle A Rodriguez, Megan Horton","doi":"10.1007/s40572-026-00538-6","DOIUrl":"https://doi.org/10.1007/s40572-026-00538-6","url":null,"abstract":"<p><strong>Purpose of review: </strong>Neurodevelopmental disorders (NDDs) such as autism spectrum disorder (ASD) and attention-deficit/hyperactivity disorder (ADHD) have been linked to environmental exposures, yet the underlying neurobiological mechanisms remain poorly understood. Magnetic resonance imaging (MRI) offers an important in vivo tool for examining how environmental neurotoxicants impact brain development. This scoping review synthesizes current evidence on the associations between air pollution, metals, environmental tobacco smoke, and endocrine-disrupting chemicals (EDCs) assessed from pregnancy through childhood and neuroimaging findings in children diagnosed with NDDs.</p><p><strong>Recent findings: </strong>We identified 14 studies examining associations between environmental exposures and MRI outcomes in children with NDDs. Air pollution exposure was linked to reduced volumes in the caudate nucleus and corpus callosum. Metal exposure was associated with changes in cortical thickness and functional connectivity, varying by metal and diagnosis. Tobacco smoke exposure correlated with reduced volumes in the cerebellum and frontal cortex and disruptions in white matter and neural networks. EDCs were linked to cortical thinning and altered task-related brain activity, with some studies reporting associations with symptom severity among children with ADHD. Overall, the literature suggests that exposure to neurotoxicants may disrupt brain development in children with NDDs. Future research should prioritize longitudinal, transdiagnostic designs with repeated exposure assessments and multimodal imaging, as well as advanced statistical modeling, to better capture the complex relationships between exposure and outcome. These findings underscore the importance of public health interventions to mitigate exposure to neurotoxicants and minimize potential neurodevelopmental risks.</p>","PeriodicalId":10775,"journal":{"name":"Current Environmental Health Reports","volume":"13 1","pages":""},"PeriodicalIF":9.1,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13132954/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147812148","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Micronutrients as Mitigators of Endocrine Disrupting Chemical Health Effects: A Scoping Review and Framework for Epidemiologic Studies.","authors":"Heather M Guetterman, Jessie P Buckley, Kasandra Sanidad, Emily Jamo, Rita S Strakovsky","doi":"10.1007/s40572-026-00536-8","DOIUrl":"https://doi.org/10.1007/s40572-026-00536-8","url":null,"abstract":"<p><strong>Purpose of review: </strong>Exposure to endocrine disrupting chemicals (EDC) is linked to numerous adverse health outcomes. However, limiting exposure to EDCs remains a significant challenge due to their widespread uses and persistence in the environment. Adequate micronutrient status supports optimal health and may offer actionable strategies for mitigating the adverse health effects of EDCs. This scoping review aimed to summarize the epidemiologic evidence on micronutrients as potential mitigators of EDC-related health outcomes, with the goal of guiding future research and methodologies.</p><p><strong>Recent findings: </strong>We identified 71 epidemiologic studies assessing micronutrients as mitigators of EDC-outcome relations, focused primarily on exposures during pregnancy (n = 34). Most studies examined phthalates and/or environmental phenols (n = 25), per- and polyfluoroalkyl substances (n = 15), polycyclic aromatic hydrocarbons (n = 10), and self-reported pesticide exposure (n = 6). Most studies suggested higher levels of some micronutrients attenuated adverse associations of EDCs with some health outcomes, particularly iodine (thyroid hormones); folic acid (fertility, birth outcomes, neurodevelopment); vitamin D (lung function, neurodevelopment); and antioxidants (birth outcomes, aging, metabolic health). However, included studies assessed a wide range of micronutrients, EDCs, and outcomes, with limited overlap across studies. This scoping review identified few topics with substantial evidence to warrant focused systematic reviews, suggesting that additional prospective research is needed, especially in at-risk populations and sensitive periods outside of pregnancy. Future epidemiologic research should consider the co-occurrence of EDCs and micronutrients in foods and include multiple methods for assessing micronutrients. Finally, to strengthen causal inference, future research should thoughtfully model potential confounding, mediation, effect measure modification, and/or statistical interaction.</p>","PeriodicalId":10775,"journal":{"name":"Current Environmental Health Reports","volume":"13 1","pages":""},"PeriodicalIF":9.1,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13132905/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147811816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Itching to know: the Microbiome, Allergic Disease, and Antimicrobial Chemicals.","authors":"Hannah E Laue, Elvira S Fleury, Megan E Romano, Anne G Hoen, Joseph M Braun","doi":"10.1007/s40572-025-00519-1","DOIUrl":"https://doi.org/10.1007/s40572-025-00519-1","url":null,"abstract":"","PeriodicalId":10775,"journal":{"name":"Current Environmental Health Reports","volume":"13 1","pages":""},"PeriodicalIF":9.1,"publicationDate":"2026-04-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147764482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Environmental Justice and Pesticides in the Global South-A Scoping Review.","authors":"Meryl Jagarnath, Leslie London, Iman Nuwayhid, Rima R Habib","doi":"10.1007/s40572-026-00535-9","DOIUrl":"10.1007/s40572-026-00535-9","url":null,"abstract":"","PeriodicalId":10775,"journal":{"name":"Current Environmental Health Reports","volume":"13 1","pages":""},"PeriodicalIF":9.1,"publicationDate":"2026-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13086650/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147697609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Shared Plant-human Biology: Herbicide Effects and New Biomarkers Perspectives.","authors":"Aline de Souza Espindola, Christine Gibson Parks, Josino Costa Moreira","doi":"10.1007/s40572-026-00523-z","DOIUrl":"10.1007/s40572-026-00523-z","url":null,"abstract":"","PeriodicalId":10775,"journal":{"name":"Current Environmental Health Reports","volume":"13 1","pages":""},"PeriodicalIF":9.1,"publicationDate":"2026-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13046696/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147590523","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An Epidemiologic Review of Endocrine-disrupting Chemicals and Understudied Gynecologic Health Conditions Affecting Quality of Life.","authors":"Samantha Schildroth, Kristen Upson, Julia Bond","doi":"10.1007/s40572-026-00534-w","DOIUrl":"https://doi.org/10.1007/s40572-026-00534-w","url":null,"abstract":"","PeriodicalId":10775,"journal":{"name":"Current Environmental Health Reports","volume":"13 1","pages":""},"PeriodicalIF":9.1,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147590535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Air Pollution and Brain Tumors in Children. A Systematic Review.","authors":"Damian Pietrzak, Mateusz Zaręba, Agata Stolecka, Roberta Zupo, Fabio Stefano Castellana, Tim S Nawrot, Luisa Lampignano, Ilaria Bortone, Rodolfo Saradone, Jarosław Madowicz, Katarzyna Musioł, Agnieszka Gruszecka-Kosowska","doi":"10.1007/s40572-026-00533-x","DOIUrl":"https://doi.org/10.1007/s40572-026-00533-x","url":null,"abstract":"","PeriodicalId":10775,"journal":{"name":"Current Environmental Health Reports","volume":"13 1","pages":""},"PeriodicalIF":9.1,"publicationDate":"2026-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147479945","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tracking Microplastics From Source to Impact: A Review of Environmental Presence, Exposure, Remediation, and Health Risks.","authors":"Imari Walker-Franklin, Anna Villalobos Santeli, Natalia Neal-Walthall","doi":"10.1007/s40572-026-00531-z","DOIUrl":"10.1007/s40572-026-00531-z","url":null,"abstract":"","PeriodicalId":10775,"journal":{"name":"Current Environmental Health Reports","volume":"13 1","pages":""},"PeriodicalIF":9.1,"publicationDate":"2026-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12995963/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147473033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Review of R Packages for Bayesian Model-based Clustering of High-dimensional Multivariate Environmental Exposures.","authors":"Briana J K Stephenson, Yiran Fu","doi":"10.1007/s40572-026-00532-y","DOIUrl":"10.1007/s40572-026-00532-y","url":null,"abstract":"","PeriodicalId":10775,"journal":{"name":"Current Environmental Health Reports","volume":"13 1","pages":""},"PeriodicalIF":9.1,"publicationDate":"2026-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12999741/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147479953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Health Effects of Living Near Petroleum and Biofuel Refineries: A Systematic Evidence Map and Scoping Review.","authors":"Marinelle Villanueva, Qi Meng, Jenni A Shearston, Rachel Morello-Frosch, Lara J Cushing","doi":"10.1007/s40572-026-00530-0","DOIUrl":"10.1007/s40572-026-00530-0","url":null,"abstract":"","PeriodicalId":10775,"journal":{"name":"Current Environmental Health Reports","volume":"13 1","pages":""},"PeriodicalIF":9.1,"publicationDate":"2026-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12988906/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147456247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}