Cosmetics最新文献_第9页

Using 3D Imaging to Preoperatively Plan Facelift Procedures for the Lower Third of the Face and Neck 使用 3D 成像术前规划面部和颈部下三分之一的拉皮手术

IF 3.3

Cosmetics Pub Date : 2024-02-11 DOI: 10.3390/cosmetics11010028

A.S. Borisenko, Valentin I. Sharobaro, A. E. Avdeev, N.S. Burkhonova, Anastasiya O. Fisun

引用次数: 0

Using 3D Imaging to Preoperatively Plan Facelift Procedures for the Lower Third of the Face and Neck 使用 3D 成像术前规划面部和颈部下三分之一的拉皮手术

IF 3.3

Cosmetics Pub Date : 2024-02-11 DOI: 10.3390/cosmetics11010028

A.S. Borisenko, Valentin I. Sharobaro, A. E. Avdeev, N.S. Burkhonova, Anastasiya O. Fisun

引用次数: 0

Antioxidant and Anti-Inflammatory Potential of Brassica oleracea Accelerates Third-Degree Burn Healing in Rats 甘蓝菜的抗氧化和抗炎潜能可加速大鼠三度烧伤的愈合

IF 3.3

Cosmetics Pub Date : 2024-02-09 DOI: 10.3390/cosmetics11010027

L. L. Miranda, M. M. Sarandy, Luciana S Altoé, Daniel Silva Sena Bastos, Fabiana Cristina Silveira Alves Melo, R. Novaes, Debora Araújo Esposito, R. V. Gonçalves

{"title":"Antioxidant and Anti-Inflammatory Potential of Brassica oleracea Accelerates Third-Degree Burn Healing in Rats","authors":"L. L. Miranda, M. M. Sarandy, Luciana S Altoé, Daniel Silva Sena Bastos, Fabiana Cristina Silveira Alves Melo, R. Novaes, Debora Araújo Esposito, R. V. Gonçalves","doi":"10.3390/cosmetics11010027","DOIUrl":"https://doi.org/10.3390/cosmetics11010027","url":null,"abstract":"Burns account for more than 265,000 deaths per year in the world, mainly associated with infections. Therefore, the shorter the healing time, the better the prognosis. Based on this, the objective of the present study was to investigate the effect of an ointment based on Brassica oleracea var. capitata extract in the third-degree healing process. Twenty-five male Wistar rats (335 ± 16 g, three months of life) were individualized in cages with food and water ad libitum. After anesthesia, two circular third-degree burn wounds (12 mm in diameter) were made on the animals, which were randomly separated into five treatments (n = 5/group), i.e., SAL: saline solution 0.9%; OV: ointment vehicle; SS: silver sulfadiazine 1%; PB1: 10% B. oleracea extract; and PB2: 20% B. oleracea extract. The animals were treated with the ointment daily for eight days. Every four days, the area and the wound contraction index were evaluated. Tissue samples were taken for histopathological analysis (cellularity, blood vessels, and extracellular matrix components) and analysis of oxidative/nitrosative status (antioxidant enzymes, lipid, and protein oxidation markers, as well as nitric oxide (NO) and hydrogen peroxide (H2O2)). The ointment based on B. oleracea var. capitata at 10 and 20% concentrations increased the number of cells, blood vessels, and fibrous components of the extracellular matrix and the activity of antioxidant enzymes, promoting a fast and efficient cutaneous repair in third-degree burn wounds.","PeriodicalId":10735,"journal":{"name":"Cosmetics","volume":null,"pages":null},"PeriodicalIF":3.3,"publicationDate":"2024-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139787997","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Antioxidant and Anti-Inflammatory Potential of Brassica oleracea Accelerates Third-Degree Burn Healing in Rats 甘蓝菜的抗氧化和抗炎潜能可加速大鼠三度烧伤的愈合

IF 3.3

Cosmetics Pub Date : 2024-02-09 DOI: 10.3390/cosmetics11010027

L. L. Miranda, M. M. Sarandy, Luciana S Altoé, Daniel Silva Sena Bastos, Fabiana Cristina Silveira Alves Melo, R. Novaes, Debora Araújo Esposito, R. V. Gonçalves

{"title":"Antioxidant and Anti-Inflammatory Potential of Brassica oleracea Accelerates Third-Degree Burn Healing in Rats","authors":"L. L. Miranda, M. M. Sarandy, Luciana S Altoé, Daniel Silva Sena Bastos, Fabiana Cristina Silveira Alves Melo, R. Novaes, Debora Araújo Esposito, R. V. Gonçalves","doi":"10.3390/cosmetics11010027","DOIUrl":"https://doi.org/10.3390/cosmetics11010027","url":null,"abstract":"Burns account for more than 265,000 deaths per year in the world, mainly associated with infections. Therefore, the shorter the healing time, the better the prognosis. Based on this, the objective of the present study was to investigate the effect of an ointment based on Brassica oleracea var. capitata extract in the third-degree healing process. Twenty-five male Wistar rats (335 ± 16 g, three months of life) were individualized in cages with food and water ad libitum. After anesthesia, two circular third-degree burn wounds (12 mm in diameter) were made on the animals, which were randomly separated into five treatments (n = 5/group), i.e., SAL: saline solution 0.9%; OV: ointment vehicle; SS: silver sulfadiazine 1%; PB1: 10% B. oleracea extract; and PB2: 20% B. oleracea extract. The animals were treated with the ointment daily for eight days. Every four days, the area and the wound contraction index were evaluated. Tissue samples were taken for histopathological analysis (cellularity, blood vessels, and extracellular matrix components) and analysis of oxidative/nitrosative status (antioxidant enzymes, lipid, and protein oxidation markers, as well as nitric oxide (NO) and hydrogen peroxide (H2O2)). The ointment based on B. oleracea var. capitata at 10 and 20% concentrations increased the number of cells, blood vessels, and fibrous components of the extracellular matrix and the activity of antioxidant enzymes, promoting a fast and efficient cutaneous repair in third-degree burn wounds.","PeriodicalId":10735,"journal":{"name":"Cosmetics","volume":null,"pages":null},"PeriodicalIF":3.3,"publicationDate":"2024-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139848070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effectiveness and Safety of Boesenbergia rotunda Extract on 3T3-L1 Preadipocytes and Its Use in Capsaicin-Loaded Body-Firming Formulation: In Vitro Biological Study and In Vivo Human Study 苧麻提取物对 3T3-L1 脂肪细胞的有效性和安全性及其在含辣椒素紧致配方中的应用：体外生物研究和体内人体研究

IF 3.3

Cosmetics Pub Date : 2024-02-07 DOI: 10.3390/cosmetics11010024

Phaijit Sritananuwat, Tipada Samseethong, Kusuma Jitsaeng, Sureewan Duangjit, P. Opanasopit, Worranan Rangsimawong

{"title":"Effectiveness and Safety of Boesenbergia rotunda Extract on 3T3-L1 Preadipocytes and Its Use in Capsaicin-Loaded Body-Firming Formulation: In Vitro Biological Study and In Vivo Human Study","authors":"Phaijit Sritananuwat, Tipada Samseethong, Kusuma Jitsaeng, Sureewan Duangjit, P. Opanasopit, Worranan Rangsimawong","doi":"10.3390/cosmetics11010024","DOIUrl":"https://doi.org/10.3390/cosmetics11010024","url":null,"abstract":"Boesenbergia rotunda has been used as an antiobesity agent by suppressing adipogenesis. This study aimed to investigate the biological activity of B. rotunda on preadipocyte cells and to evaluate the effectiveness and safety of using B. rotunda extract in a capsaicin-loaded body-firming formulation. The antiadipogenesis of B. rotunda ethanolic extract was evaluated in 3T3-L1 preadipocyte cells. After the application of the B. rotunda extract-loaded body-firming formulation on the skin of volunteers for 28 d, thigh circumference, melanin index, and skin erythema were investigated. The results showed that the ethanolic extract of B. rotunda was not toxic toward 3T3-L1 cells at concentrations lower than 20 µg/mL, with antiadipogenesis of the B. rotunda extract occurring at a concentration of 1 µg/mL. The B. rotunda extract containing panduratin A was mixed with capsaicin body-firming products and successfully permeated into and through the skin. Applying this formulation to the thighs of the volunteers two times a day for 21 days led to a significant reduction in thigh circumference and melanin index. A slight elevation in skin erythema was observed, but there was no significant increase in redness or pain. In conclusion, the B. rotunda extract contained bioactive compounds that inhibited antiadipogenesis. The formulations containing B. rotunda extract and capsaicin showed potential as effective body-firming products.","PeriodicalId":10735,"journal":{"name":"Cosmetics","volume":null,"pages":null},"PeriodicalIF":3.3,"publicationDate":"2024-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139797927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effectiveness and Safety of Boesenbergia rotunda Extract on 3T3-L1 Preadipocytes and Its Use in Capsaicin-Loaded Body-Firming Formulation: In Vitro Biological Study and In Vivo Human Study 苧麻提取物对 3T3-L1 脂肪细胞的有效性和安全性及其在含辣椒素紧致配方中的应用：体外生物研究和体内人体研究

IF 3.3

Cosmetics Pub Date : 2024-02-07 DOI: 10.3390/cosmetics11010024

Phaijit Sritananuwat, Tipada Samseethong, Kusuma Jitsaeng, Sureewan Duangjit, P. Opanasopit, Worranan Rangsimawong

{"title":"Effectiveness and Safety of Boesenbergia rotunda Extract on 3T3-L1 Preadipocytes and Its Use in Capsaicin-Loaded Body-Firming Formulation: In Vitro Biological Study and In Vivo Human Study","authors":"Phaijit Sritananuwat, Tipada Samseethong, Kusuma Jitsaeng, Sureewan Duangjit, P. Opanasopit, Worranan Rangsimawong","doi":"10.3390/cosmetics11010024","DOIUrl":"https://doi.org/10.3390/cosmetics11010024","url":null,"abstract":"Boesenbergia rotunda has been used as an antiobesity agent by suppressing adipogenesis. This study aimed to investigate the biological activity of B. rotunda on preadipocyte cells and to evaluate the effectiveness and safety of using B. rotunda extract in a capsaicin-loaded body-firming formulation. The antiadipogenesis of B. rotunda ethanolic extract was evaluated in 3T3-L1 preadipocyte cells. After the application of the B. rotunda extract-loaded body-firming formulation on the skin of volunteers for 28 d, thigh circumference, melanin index, and skin erythema were investigated. The results showed that the ethanolic extract of B. rotunda was not toxic toward 3T3-L1 cells at concentrations lower than 20 µg/mL, with antiadipogenesis of the B. rotunda extract occurring at a concentration of 1 µg/mL. The B. rotunda extract containing panduratin A was mixed with capsaicin body-firming products and successfully permeated into and through the skin. Applying this formulation to the thighs of the volunteers two times a day for 21 days led to a significant reduction in thigh circumference and melanin index. A slight elevation in skin erythema was observed, but there was no significant increase in redness or pain. In conclusion, the B. rotunda extract contained bioactive compounds that inhibited antiadipogenesis. The formulations containing B. rotunda extract and capsaicin showed potential as effective body-firming products.","PeriodicalId":10735,"journal":{"name":"Cosmetics","volume":null,"pages":null},"PeriodicalIF":3.3,"publicationDate":"2024-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139857792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Efficacy and Skin Microbiome Modulation Effects of a Fixed-Concentration Combination of Benzoyl Peroxide 4% Plus Niacinamide 4% in a Film-Forming Cream in Subjects with Mild-to-Moderate Acne: A Non-Sponsored, Prospective, Assessor-Blinded, Pilot Trial 过氧化苯甲酰 4% 和烟酰胺 4% 固定浓度组合的成膜霜对轻度至中度痤疮受试者的疗效和皮肤微生物群调节作用：一项非赞助、前瞻性、评估者对照的试点试验

IF 3.3

Cosmetics Pub Date : 2024-02-07 DOI: 10.3390/cosmetics11010025

M. Puviani, K. Eisendle

{"title":"Efficacy and Skin Microbiome Modulation Effects of a Fixed-Concentration Combination of Benzoyl Peroxide 4% Plus Niacinamide 4% in a Film-Forming Cream in Subjects with Mild-to-Moderate Acne: A Non-Sponsored, Prospective, Assessor-Blinded, Pilot Trial","authors":"M. Puviani, K. Eisendle","doi":"10.3390/cosmetics11010025","DOIUrl":"https://doi.org/10.3390/cosmetics11010025","url":null,"abstract":"Benzoyl peroxide (BPO) and niacinamide (Niac) are commonly used alone or in combination with other molecules in the treatment of acne. BPO and Niac in the same product could exert complementary and synergistic effects improving efficacy in acne. Furthermore, Niac could reduce some side effects of BPO, such as skin irritation and erythema. A film-forming cream product containing BPO 4% and Niac 4%, vehiculated in a mixture of polyvinyl alcohol (PVA) and perfluoropolyether (PFPE) has been recently developed (B-N cream). A 28-day, assessor-blinded pilot trial was conducted to evaluate the clinical efficacy, skin tolerability, sebum production, skin redness, and skin microbiome modulation of B-N cream in subjects with mild to moderate acne of the face. Twenty-two adult men and women with mild-to-moderate acne of the face participated in this trial, after their written informed consent. B-N cream was applied once daily in the evening. The use of B-N cream was associated with a statistically significant decrease in acne lesions after treatment in comparison with baseline (non-inflammatory lesions: −40%; inflammatory lesions: −43% and total lesions: −41%). The use of the cream was not associated with a skin barrier function alteration. The skin redness score (−11%) and the sebum production (−42%) were significantly reduced after treatment. The use of B-N cream determined a reduction in the relative abundance of the Actinobacteria phylum (Corynebacterium and Propionibacterium, from 56% to 47%) and a significant increase in the abundance of Bacteroidetes phylum (from 3% to 5.2%). In addition, the product was well tolerated. In conclusion, this film-forming, medical device cream was effective in subjects with mild-to-moderate acne, reducing acne lesions and sebum production without altering skin barrier function, offering good skin tolerability. Furthermore, this product exerts positive skin microbiome modulation effects.","PeriodicalId":10735,"journal":{"name":"Cosmetics","volume":null,"pages":null},"PeriodicalIF":3.3,"publicationDate":"2024-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139854776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Skin Anti-Aging Efficacy of a Lactobacillus plantarum GT-17F Fermented Dendrobium officinale Ingredient: A Randomized, Double-Blind, Placebo-Controlled Clinical Study 植物乳杆菌 GT-17F 发酵铁皮石斛成分的皮肤抗衰老功效：随机、双盲、安慰剂对照临床研究

IF 3.3

Cosmetics Pub Date : 2024-02-07 DOI: 10.3390/cosmetics11010026

Weicheng Fei, M. Noda, Narandalai Danshiitsoodol, Masanori Sugiyama

{"title":"Skin Anti-Aging Efficacy of a Lactobacillus plantarum GT-17F Fermented Dendrobium officinale Ingredient: A Randomized, Double-Blind, Placebo-Controlled Clinical Study","authors":"Weicheng Fei, M. Noda, Narandalai Danshiitsoodol, Masanori Sugiyama","doi":"10.3390/cosmetics11010026","DOIUrl":"https://doi.org/10.3390/cosmetics11010026","url":null,"abstract":"We previously found that fermented extract of Dendrobium officinale using Lactobacillus plantarum GT-17F has a stronger antioxidant effect, especially in free radical scavenging. The result provided a basis for further studies to evaluate the effectiveness of fermented D. officinale in preventing UV-mediated damage and photoaging in humans. Therefore, in this study, we aimed to assess the anti-aging efficacy of D. officinale fermented with GT-17F strain in a clinical trial, which was conducted as a double-blind, placebo-controlled, randomized parallel-group comparative study with 99 volunteers with visible wrinkles. During the study, subjects were instructed to apply one pump of each essence, which contains fermented, unfermented, or no D. officinale extract, evenly to their face, both in the morning and evening, following their cleansing routine. At 28 days post-treatment, compared to baseline, subjects in the fermented extract group demonstrated significant improvements in stratum corneum water content, skin elasticity, skin glossiness, wrinkle area and ratio, erythema area, and erythema area ratio. In contrast, the unfermented extract group showed a significant difference only in improving erythema index levels in the skin. This comprehensive study has rigorously investigated the anti-aging effects of D. officinale and its fermented version on human skin, highlighting a notable contribution to dermatological research.","PeriodicalId":10735,"journal":{"name":"Cosmetics","volume":null,"pages":null},"PeriodicalIF":3.3,"publicationDate":"2024-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139795633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Efficacy and Skin Microbiome Modulation Effects of a Fixed-Concentration Combination of Benzoyl Peroxide 4% Plus Niacinamide 4% in a Film-Forming Cream in Subjects with Mild-to-Moderate Acne: A Non-Sponsored, Prospective, Assessor-Blinded, Pilot Trial 过氧化苯甲酰 4% 和烟酰胺 4% 固定浓度组合的成膜霜对轻度至中度痤疮受试者的疗效和皮肤微生物群调节作用：一项非赞助、前瞻性、评估者对照的试点试验

IF 3.3

Cosmetics Pub Date : 2024-02-07 DOI: 10.3390/cosmetics11010025

M. Puviani, K. Eisendle

{"title":"Efficacy and Skin Microbiome Modulation Effects of a Fixed-Concentration Combination of Benzoyl Peroxide 4% Plus Niacinamide 4% in a Film-Forming Cream in Subjects with Mild-to-Moderate Acne: A Non-Sponsored, Prospective, Assessor-Blinded, Pilot Trial","authors":"M. Puviani, K. Eisendle","doi":"10.3390/cosmetics11010025","DOIUrl":"https://doi.org/10.3390/cosmetics11010025","url":null,"abstract":"Benzoyl peroxide (BPO) and niacinamide (Niac) are commonly used alone or in combination with other molecules in the treatment of acne. BPO and Niac in the same product could exert complementary and synergistic effects improving efficacy in acne. Furthermore, Niac could reduce some side effects of BPO, such as skin irritation and erythema. A film-forming cream product containing BPO 4% and Niac 4%, vehiculated in a mixture of polyvinyl alcohol (PVA) and perfluoropolyether (PFPE) has been recently developed (B-N cream). A 28-day, assessor-blinded pilot trial was conducted to evaluate the clinical efficacy, skin tolerability, sebum production, skin redness, and skin microbiome modulation of B-N cream in subjects with mild to moderate acne of the face. Twenty-two adult men and women with mild-to-moderate acne of the face participated in this trial, after their written informed consent. B-N cream was applied once daily in the evening. The use of B-N cream was associated with a statistically significant decrease in acne lesions after treatment in comparison with baseline (non-inflammatory lesions: −40%; inflammatory lesions: −43% and total lesions: −41%). The use of the cream was not associated with a skin barrier function alteration. The skin redness score (−11%) and the sebum production (−42%) were significantly reduced after treatment. The use of B-N cream determined a reduction in the relative abundance of the Actinobacteria phylum (Corynebacterium and Propionibacterium, from 56% to 47%) and a significant increase in the abundance of Bacteroidetes phylum (from 3% to 5.2%). In addition, the product was well tolerated. In conclusion, this film-forming, medical device cream was effective in subjects with mild-to-moderate acne, reducing acne lesions and sebum production without altering skin barrier function, offering good skin tolerability. Furthermore, this product exerts positive skin microbiome modulation effects.","PeriodicalId":10735,"journal":{"name":"Cosmetics","volume":null,"pages":null},"PeriodicalIF":3.3,"publicationDate":"2024-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139795033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Skin Anti-Aging Efficacy of a Lactobacillus plantarum GT-17F Fermented Dendrobium officinale Ingredient: A Randomized, Double-Blind, Placebo-Controlled Clinical Study 植物乳杆菌 GT-17F 发酵铁皮石斛成分的皮肤抗衰老功效：随机、双盲、安慰剂对照临床研究

IF 3.3

Cosmetics Pub Date : 2024-02-07 DOI: 10.3390/cosmetics11010026

Weicheng Fei, M. Noda, Narandalai Danshiitsoodol, Masanori Sugiyama

{"title":"Skin Anti-Aging Efficacy of a Lactobacillus plantarum GT-17F Fermented Dendrobium officinale Ingredient: A Randomized, Double-Blind, Placebo-Controlled Clinical Study","authors":"Weicheng Fei, M. Noda, Narandalai Danshiitsoodol, Masanori Sugiyama","doi":"10.3390/cosmetics11010026","DOIUrl":"https://doi.org/10.3390/cosmetics11010026","url":null,"abstract":"We previously found that fermented extract of Dendrobium officinale using Lactobacillus plantarum GT-17F has a stronger antioxidant effect, especially in free radical scavenging. The result provided a basis for further studies to evaluate the effectiveness of fermented D. officinale in preventing UV-mediated damage and photoaging in humans. Therefore, in this study, we aimed to assess the anti-aging efficacy of D. officinale fermented with GT-17F strain in a clinical trial, which was conducted as a double-blind, placebo-controlled, randomized parallel-group comparative study with 99 volunteers with visible wrinkles. During the study, subjects were instructed to apply one pump of each essence, which contains fermented, unfermented, or no D. officinale extract, evenly to their face, both in the morning and evening, following their cleansing routine. At 28 days post-treatment, compared to baseline, subjects in the fermented extract group demonstrated significant improvements in stratum corneum water content, skin elasticity, skin glossiness, wrinkle area and ratio, erythema area, and erythema area ratio. In contrast, the unfermented extract group showed a significant difference only in improving erythema index levels in the skin. This comprehensive study has rigorously investigated the anti-aging effects of D. officinale and its fermented version on human skin, highlighting a notable contribution to dermatological research.","PeriodicalId":10735,"journal":{"name":"Cosmetics","volume":null,"pages":null},"PeriodicalIF":3.3,"publicationDate":"2024-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139855671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0