COPD: Journal of Chronic Obstructive Pulmonary Disease最新文献

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Perceptions of Sedentary Behaviour in People with Chronic Obstructive Pulmonary Disease (COPD) Following a Recent Hospital-Managed Exacerbation: A Qualitative Exploration. 慢性阻塞性肺疾病(COPD)患者在近期医院管理恶化后的久坐行为认知:一项定性探索
IF 2.1 4区 医学
COPD: Journal of Chronic Obstructive Pulmonary Disease Pub Date : 2025-12-01 Epub Date: 2025-09-04 DOI: 10.1080/15412555.2025.2550430
Stefanie Harding, Angela Glynn, Alan Richardson, Ana-Carolina Gonçalves, Luke Hodgson
{"title":"Perceptions of Sedentary Behaviour in People with Chronic Obstructive Pulmonary Disease (COPD) Following a Recent Hospital-Managed Exacerbation: A Qualitative Exploration.","authors":"Stefanie Harding, Angela Glynn, Alan Richardson, Ana-Carolina Gonçalves, Luke Hodgson","doi":"10.1080/15412555.2025.2550430","DOIUrl":"https://doi.org/10.1080/15412555.2025.2550430","url":null,"abstract":"<p><strong>Background: </strong>Individuals with chronic obstructive pulmonary disease (COPD) often lead sedentary lives, which is linked to negative health outcomes. Understanding the causes of this behaviour is essential for designing effective interventions. In the time following a hospital discharge, people with COPD may be especially sedentary and develop habits that contribute to this behaviour. Therefore, this is an important point at which to evaluate the reasons behind sedentary behaviour.</p><p><strong>Methods: </strong>From one acute hospital in England, 12 participants with a recent COPD exacerbation were recruited. Following discharge, semi-structured interviews were conducted to identify perceptions of and barriers and facilitators to reducing sedentary behaviour. Reflexive thematic analysis was employed.</p><p><strong>Findings: </strong>Two themes developed: \"Focusing on survival\" and \"Loneliness, social isolation and lack of purpose\". Factors contributing to sedentary behaviour include the need for rest, social isolation, symptom management, fear of dying or being readmitted to hospital from over-exertion, adherence to health professional advice, and lack of motivation and purpose. Concerns about socioeconomic disparities were noted. Participants were ready to embrace positive lifestyle changes.</p><p><strong>Conclusion: </strong>Our study found some people with COPD, recently discharged from hospital, may adopt a sedentary lifestyle to manage symptoms and daily activities. Interviews highlight the need to tackle socioeconomic disparities, social support, and feelings of social disconnection. Misconceptions about sedentary behaviour being part of recovery underline the need for education for individuals with COPD and health professionals. The findings suggest strategies to reduce sedentary time, such as enjoyable activities, community involvement, and incorporating sedentary behaviour reduction into pulmonary rehabilitation.</p>","PeriodicalId":10704,"journal":{"name":"COPD: Journal of Chronic Obstructive Pulmonary Disease","volume":"22 1","pages":"2550430"},"PeriodicalIF":2.1,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144990928","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Current Practices on Prescribing and Deprescribing for Patients on Long-Term Antibiotic Treatment for Chronic Pulmonary Conditions: An Umbrella Review by the European Society of Clinical Pharmacy (ESCP). 慢性肺部疾病患者长期抗生素治疗的处方和处方的现行做法:欧洲临床药学学会(ESCP)的综合综述。
IF 2.1 4区 医学
COPD: Journal of Chronic Obstructive Pulmonary Disease Pub Date : 2025-12-01 Epub Date: 2025-07-28 DOI: 10.1080/15412555.2025.2532076
Ivana Tadic, Daniela Fialová, Ankie Hazen, Martin C Henman, Betul Okuyan, Francesca Wirth, Abdikarim Abdi, Silvana Urru, Kayla R Stover, Anita E Weidmann
{"title":"Current Practices on Prescribing and Deprescribing for Patients on Long-Term Antibiotic Treatment for Chronic Pulmonary Conditions: An Umbrella Review by the European Society of Clinical Pharmacy (ESCP).","authors":"Ivana Tadic, Daniela Fialová, Ankie Hazen, Martin C Henman, Betul Okuyan, Francesca Wirth, Abdikarim Abdi, Silvana Urru, Kayla R Stover, Anita E Weidmann","doi":"10.1080/15412555.2025.2532076","DOIUrl":"10.1080/15412555.2025.2532076","url":null,"abstract":"<p><strong>Purpose: </strong>Chronic pulmonary conditions require complex treatment strategies involving long-term antibiotic treatment, which carries the highest risk of antimicrobial resistance and adverse drug events (ADE). Specific guidance on prescribing and deprescribing can help reduce these risks and improve therapy effectiveness. The aim of the study was to determine prescribing and deprescribing practices for long-term antibiotic treatment (≥30 days) in preventing exacerbations of stable chronic pulmonary conditions in adult patients across all healthcare settings.</p><p><strong>Patients and methods: </strong>This umbrella review was part of a larger registered study (PROSPERO, CRD42022381268) including systematic reviews and meta-analyses retrieved from PubMed, Cochrane Library, and PsycInfo. Outcomes of interest included condition, antibiotic, dose, duration, (de-) prescribing advice. Standardized methodological tools were used to assess methodological quality of the selected publications (ROBIS), facilitate data extraction (EPOC), and guide narrative summary of findings (PRIOR).</p><p><strong>Results: </strong>In total, <i>n</i> = 14 publications were analyzed. (De-)prescribing advice is summarized for treatment (≥30 days) of chronic obstructive pulmonary disease, asthma, non-cystic fibrosis bronchiectasis, cystic fibrosis, and bronchiolitis obliterans syndrome. Macrolides are the most commonly recommended antibiotic for stable chronic pulmonary conditions. ADEs are the main reason for antibiotic discontinuation. Little consideration is given to emergence of antibiotic resistance.</p><p><strong>Conclusion: </strong>There is a significant paucity of literature providing specific (de-)prescribing advice for clinical practice. More precise recommendations are required in view of patient safety.</p>","PeriodicalId":10704,"journal":{"name":"COPD: Journal of Chronic Obstructive Pulmonary Disease","volume":"22 1","pages":"2532076"},"PeriodicalIF":2.1,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144728487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence, Risk Factors, and Antibiotic Intervention of Lower Airway Pseudomonas aeruginosa Colonization in Patients with Stable Chronic Obstructive Pulmonary Disease: a Systematic Review and Meta-Analysis. 稳定期慢性阻塞性肺疾病患者下气道铜绿假单胞菌定植的患病率、危险因素和抗生素干预:系统回顾和荟萃分析
IF 2.1 4区 医学
COPD: Journal of Chronic Obstructive Pulmonary Disease Pub Date : 2025-12-01 Epub Date: 2025-10-02 DOI: 10.1080/15412555.2025.2564743
Yanbing Liu, Yan Wang, Jingwei Qiu, Tao Li, Lihua Zhou, Yunping Song, Ling Hu
{"title":"Prevalence, Risk Factors, and Antibiotic Intervention of Lower Airway <i>Pseudomonas aeruginosa</i> Colonization in Patients with Stable Chronic Obstructive Pulmonary Disease: a Systematic Review and Meta-Analysis.","authors":"Yanbing Liu, Yan Wang, Jingwei Qiu, Tao Li, Lihua Zhou, Yunping Song, Ling Hu","doi":"10.1080/15412555.2025.2564743","DOIUrl":"https://doi.org/10.1080/15412555.2025.2564743","url":null,"abstract":"<p><strong>Background and objectives: </strong>Bacterial colonization or chronic infection occurs in the lower respiratory tract of patients with chronic obstructive pulmonary disease (COPD). Previous studies on Pseudomonas aeruginosa (PA) colonization in patients with stable COPD mainly focused on its impact on prognosis, such as leading to acute exacerbations and increased mortality. However, the prevalence of PA colonization remains unknown. Evidence-based medicine is lacking regarding the association of prior antibiotics and inhaled corticosteroids (ICSs) exposure with PA colonization, intervention with antibiotic therapy for acute exacerbations, and the effect of PA eradication. We conducted this systematic review and meta-analysis to investigate these issues and inform precise treatment and prevention.</p><p><strong>Methods: </strong>We searched PubMed, Embase, Google Scholar, Cochrane, China National Knowledge Infrastructure (CNKI), and ClinicalTrials.gov for randomized controlled trials (RCTs) and observational studies. The primary outcome was prevalence. Secondary outcomes included previous antibiotic and ICS exposure, exacerbations after antibiotic therapy, and the eradication rate of PA with inhaled antibiotics (IAs).</p><p><strong>Results: </strong>A total of 39 studies were included, comprising 32,753 cases. The pooled prevalence was 5.6% (95% CI 0.04-0.07). Previous exposure to antibiotics and ICSs was associated with increased PA colonization, with odds ratio (OR) values of (OR = 2.85, 95% CI 1.62-5.01) and (OR = 1.89, 95% CI 1.12-3.19), respectively. Exacerbations decreased within the next year after azithromycin treatment (standardized mean difference [SMD] = -0.43, 95% CI -0.77 to -0.10). The eradication rate of PA with IAs was 0.52 (95% CI 0.46-0.57), and IAs reduced exacerbations in the following year (SMD = -0.87, 95% CI -1.38 to -0.35).</p><p><strong>Conclusion: </strong>The prevalence of PA colonization in stable COPD was approximately 5.6%. Prior exposure to antibiotics and ICSs increased the risk of PA colonization. Azithromycin therapy reduced exacerbations in PA colonized COPD patients. The eradication rate of PA within one year after IA therapy was about 52%, and exacerbations decreased.</p>","PeriodicalId":10704,"journal":{"name":"COPD: Journal of Chronic Obstructive Pulmonary Disease","volume":"22 1","pages":"2564743"},"PeriodicalIF":2.1,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145212036","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Roles of ABCA1 in Chronic Obstructive Pulmonary Disease. ABCA1在慢性阻塞性肺疾病中的作用
IF 2.2 4区 医学
COPD: Journal of Chronic Obstructive Pulmonary Disease Pub Date : 2025-12-01 Epub Date: 2025-04-29 DOI: 10.1080/15412555.2025.2493701
Ying Gu, Xiaoqing Bi, Xiaofei Liu, Qingqing Qian, Yiqiong Wen, Shu Hua, Qiaoli Fu, Yuanyuan Zheng, Shibo Sun
{"title":"Roles of ABCA1 in Chronic Obstructive Pulmonary Disease.","authors":"Ying Gu, Xiaoqing Bi, Xiaofei Liu, Qingqing Qian, Yiqiong Wen, Shu Hua, Qiaoli Fu, Yuanyuan Zheng, Shibo Sun","doi":"10.1080/15412555.2025.2493701","DOIUrl":"https://doi.org/10.1080/15412555.2025.2493701","url":null,"abstract":"<p><p>Chronic obstructive pulmonary disease (COPD) is one of the common chronic respiratory diseases, which causes a heavy burden to patients and society. Increasing studies suggest that ABCA1 plays an important role in COPD. ABCA1 belongs to a large class of ATP-binding (ABC) transporters. It is not only involved in the reverse transport of cholesterol, but also in the regulation of apoptosis, pyroptosis, cellular inflammation and cellular immunity. Meanwhile, ABCA1 is involved in several signaling pathways, such as SREBP pathway, LXR pathway, MAPK pathway, p62/mTOR pathway, CTRP1 pathway and so on. In addition, the ABCA1 participates in the disorder of lipid metabolism in COPD by regulating the formation of RCT and HDL, regulates the inflammation of COPD by removing excess cholesterol in macrophages, and promotes the differentiation of COPD phenotype into emphysema type. Accordingly, the ABCA1 may be a therapeutic target for COPD.</p>","PeriodicalId":10704,"journal":{"name":"COPD: Journal of Chronic Obstructive Pulmonary Disease","volume":"22 1","pages":"2493701"},"PeriodicalIF":2.2,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143986454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Biologics in COPD: The Road is Still Long and Winding. 慢性阻塞性肺病的生物制剂:道路仍然漫长而曲折。
IF 2.2 4区 医学
COPD: Journal of Chronic Obstructive Pulmonary Disease Pub Date : 2025-12-01 Epub Date: 2025-02-24 DOI: 10.1080/15412555.2025.2467657
Konstantinos Kostikas, Athena Gogali
{"title":"Biologics in COPD: The Road is Still Long and Winding.","authors":"Konstantinos Kostikas, Athena Gogali","doi":"10.1080/15412555.2025.2467657","DOIUrl":"https://doi.org/10.1080/15412555.2025.2467657","url":null,"abstract":"","PeriodicalId":10704,"journal":{"name":"COPD: Journal of Chronic Obstructive Pulmonary Disease","volume":"22 1","pages":"2467657"},"PeriodicalIF":2.2,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143482412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Meta-Analysis of the Effect of Aerobic Exercise Combined with Respiratory Training on Stable Chronic Obstructive Pulmonary Disease. 有氧运动联合呼吸训练对稳定期慢性阻塞性肺疾病疗效的meta分析。
IF 2.1 4区 医学
COPD: Journal of Chronic Obstructive Pulmonary Disease Pub Date : 2025-12-01 Epub Date: 2025-07-30 DOI: 10.1080/15412555.2025.2519598
Nixi Huang, Lina Peng, Hongjie Li, Juncheng Si, Lei Shi, Yu Wang, Jiangrui Liao, Lili Sun
{"title":"Meta-Analysis of the Effect of Aerobic Exercise Combined with Respiratory Training on Stable Chronic Obstructive Pulmonary Disease.","authors":"Nixi Huang, Lina Peng, Hongjie Li, Juncheng Si, Lei Shi, Yu Wang, Jiangrui Liao, Lili Sun","doi":"10.1080/15412555.2025.2519598","DOIUrl":"10.1080/15412555.2025.2519598","url":null,"abstract":"<p><p><b>Purpose:</b> The purpose of this study was to conduct a meta-analysis of the effects of aerobic exercise combined with respiratory training on patients with stable chronic obstructive pulmonary disease (COPD). <b>Methods:</b> The data of randomized controlled trials on the effects of aerobic exercise combined with respiratory training on patients with stable COPD published up to March 2024 were retrieved from six electronic databases (PubMed, Web of Science, Cochrane Library, Embase, CNKI and China Science and Technology Journal Database). The risk of bias and quality of evidence were assessed using the Cochrane Collaboration tool, and the Physiotherapy Evidence Database (PEDro) Scale approach, respectively. <b>Results:</b> A total of 9 eligible trials with 449 patients with stable COPD were identified. The quality of evidence was moderate. Compared with the control group, the meta-analysis of aerobic exercise combined with respiratory training revealed a significant improvement in the St. George's Respiratory Disease Questionnaire (SGRQ) score (standardized mean difference) (SMD=-0.68, 95% CI [-0.98, -0.39], <i>p</i> < 0.0001), 6-minute walking distance (6MWD) (standardized mean difference) (SMD = 0.84, 95% CI [0.58, 1.11], <i>p</i> < 0.00001), and exercise time (mean difference) (MD = 2.45, 95% CI [0.46, 4.44], <i>p</i> = 0.02). Moreover, aerobic exercise combined with respiratory training improved the secondary outcome measures. These included the modified Medical Research Council dyspnea Scale (mMRC) (SMD=-0.89, 95% CI [-1.32, -0.46], <i>p</i> < 0.00001), Chronic Respiratory Disease Questionnaire (CRQ) (MD = 1.43, 95% CI [-0.56, 3.41], <i>p</i> = 0.16). <b>Conclusion:</b> The results showed that this combination therapy significantly improved the patient's exercise endurance, effectively alleviated the symptoms of dyspnea, and significantly improved the patient's health-related quality of life.</p>","PeriodicalId":10704,"journal":{"name":"COPD: Journal of Chronic Obstructive Pulmonary Disease","volume":"22 1","pages":"2519598"},"PeriodicalIF":2.1,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144752626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Genetic Association of Lipid-Lowering Drug Target Genes with Chronic Obstructive Pulmonary Disease: A Mendelian Randomization Study. 降脂药物靶基因与慢性阻塞性肺疾病的遗传关联:孟德尔随机研究
IF 2.2 4区 医学
COPD: Journal of Chronic Obstructive Pulmonary Disease Pub Date : 2025-12-01 Epub Date: 2025-06-16 DOI: 10.1080/15412555.2025.2513601
Hao Luan, Tianhua Wang, Rui Wang, Yu Wang, Yu Liu, Wenru Sheng, Jiaqi Guo, Haotian Ji, Xiufeng Liu, Xiqing Xue, Yiider Tseng
{"title":"Genetic Association of Lipid-Lowering Drug Target Genes with Chronic Obstructive Pulmonary Disease: A Mendelian Randomization Study.","authors":"Hao Luan, Tianhua Wang, Rui Wang, Yu Wang, Yu Liu, Wenru Sheng, Jiaqi Guo, Haotian Ji, Xiufeng Liu, Xiqing Xue, Yiider Tseng","doi":"10.1080/15412555.2025.2513601","DOIUrl":"https://doi.org/10.1080/15412555.2025.2513601","url":null,"abstract":"<p><p>The role of lipid-lowering drugs in chronic obstructive pulmonary disease (COPD) is controversial in clinical studies. This study aimed to explore the causal relationship between lipid-lowering drugs and COPD from a genetic perspective, and to evaluate the potential effects of this relationship. Four hundred and thirty-one lipid-related phenotypes and two COPD datasets were obtained from Genome-Wide Association Studies (GWAS) and analysed together using Mendelian randomization (MR). Genetic variants associated with genes encoding targets of lipid-lowering drugs were extracted from the Global Lipid Genetics Consortium. Expression quantitative trait loci data in relevant tissues were adopted to validate lipid-lowering drug targets that reached significance. We found that four lipid abnormalities were associated with COPD risk. Genetically proxied inhibition of HMG-CoA reductase (HMGCR) and PCSK9 is associated with an increased risk of COPD. And there is a significant MR correlation between increased whole blood HMGCR expression and COPD. HMGCR and PCSK9 inhibitors are associated with onset of COPD, lung function, and COPD-associated infections. Mediation analyses were performed to explore potential mediators of how genetically proxied inhibition of HMGCR and PCSK9 influences the risk of COPD through different immune cell phenotypes and inflammatory factor levels. Our findings indicate a potential link between the use of HMGCR and PCSK9 inhibitors and increased risk of COPD and exacerbation of COPD phenotypes. This suggests effects beyond LDL-C modulation, potentially involving immune cell function and inflammatory factors.</p>","PeriodicalId":10704,"journal":{"name":"COPD: Journal of Chronic Obstructive Pulmonary Disease","volume":"22 1","pages":"2513601"},"PeriodicalIF":2.2,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144301289","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effectiveness of Interventions to Reduce Sedentary Behaviour in People with Chronic Obstructive Pulmonary Disease: A Systematic Review of Randomised Controlled Trials. 减少慢性阻塞性肺疾病患者久坐行为的干预措施的有效性:随机对照试验的系统回顾
IF 2.1 4区 医学
COPD: Journal of Chronic Obstructive Pulmonary Disease Pub Date : 2025-12-01 Epub Date: 2025-04-09 DOI: 10.1080/15412555.2025.2482710
Stefanie Harding, Alan Richardson, Angela Glynn, Luke Hodgson
{"title":"Effectiveness of Interventions to Reduce Sedentary Behaviour in People with Chronic Obstructive Pulmonary Disease: A Systematic Review of Randomised Controlled Trials.","authors":"Stefanie Harding, Alan Richardson, Angela Glynn, Luke Hodgson","doi":"10.1080/15412555.2025.2482710","DOIUrl":"10.1080/15412555.2025.2482710","url":null,"abstract":"<p><strong>Background: </strong>Chronic obstructive pulmonary disease (COPD) affects over 300 million people and is the third leading cause of death. People with COPD spend a large amount of their day sedentary, which is associated with reduced life expectancy.</p><p><strong>Methods: </strong>A systematic search was conducted across electronic databases, including Medline, CINAHL, PsycINFO, and Cochrane Library. Due to the heterogeneity of study design and siting of the activity monitor, a narrative synthesis was conducted.</p><p><strong>Results: </strong>1086 studies were identified; six met inclusion criteria, and two reported a decreased sedentary time. Nordic walking reduced sedentary time by 128 minutes/day compared to baseline, significantly more than the control group (<i>p</i> < 0.01). Another study using a behaviour change intervention reduced sedentary behaviour by 64 minutes/day compared to baseline, significantly more than the control group (<i>p</i> = 0.018). Both studies were conducted for over 12 weeks, with a multi-modal approach incorporating behaviour change techniques, goal setting, education, self-monitoring and feedback. No studies focusing on reducing sedentary behaviour alone reported significant changes.</p><p><strong>Conclusions: </strong>Few interventional studies have focused on reducing sedentary behaviour in people with COPD. Interventions that have effectively reduced sedentary time primarily focused on physical activity and adopted a multi-modal strategy. This suggests that future interventions could consider a multi-modal approach, which includes behaviour change and the incorporation of enjoyable light physical activities into daily living. We cannot conclude from the available evidence that solely targeting sedentary time will reduce sedentary behaviour. Longer interventions may reduce sedentary behaviour, but there is a lack of studies on both short- and long-term approaches.PROSPERO registration number CRD 42024510434.</p>","PeriodicalId":10704,"journal":{"name":"COPD: Journal of Chronic Obstructive Pulmonary Disease","volume":"22 1","pages":"2482710"},"PeriodicalIF":2.1,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144728488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Psychometric Evaluation of the Assessment of the Burden of COPD Scale According to the Rasch Model. 基于Rasch模型的慢性阻塞性肺病负担量表评估的心理测量学评价。
IF 2.1 4区 医学
COPD: Journal of Chronic Obstructive Pulmonary Disease Pub Date : 2025-09-06 Epub Date: 2025-09-16 DOI: 10.1080/15412555.2025.2557232
Maarten Voorhaar, Antoine Regnault, Onno C P van Schayck, Jean Muris, Annerika H M Slok
{"title":"Psychometric Evaluation of the Assessment of the Burden of COPD Scale According to the Rasch Model.","authors":"Maarten Voorhaar, Antoine Regnault, Onno C P van Schayck, Jean Muris, Annerika H M Slok","doi":"10.1080/15412555.2025.2557232","DOIUrl":"10.1080/15412555.2025.2557232","url":null,"abstract":"<p><p>To facilitate shared decision-making in Chronic obstructive pulmonary disease (COPD), the Assessment of the Burden of COPD (ABC) tool was developed. An integral part of the ABC tool is the ABC scale, a questionnaire to determine COPD burden. The psychometric evidence of the ABC scale is limited. If the data would fit the Rasch model, more accurate scoring would be possible. This would improve the use of the ABC tool. Therefore, the aim of this study is to validate the ABC scale using the Rasch model. We conducted a secondary analysis based on data collected in a pragmatic RCT using Rasch model theory. The ordering of thresholds, reliability and targeting were analysed, and we tested unidimensionality, local independence of items (LD), fit of the data with the model and measurement invariance between groups (DIF). We analysed 551 samples from 176 patients. The analyses confirmed that the ABC scale is a reliable instrument. However, initial analysis showed a poor fit of the data to the Rasch model. After recoding the response options and analysing the fit of the data for the subdomains of the ABC scale, we found ordered thresholds and a good overall model fit. This analysis indicates that the ABC scale assessed three distinct sub-domains: symptoms, physical functioning, and emotional health. We conclude that the ABC scale is a valid instrument to assess COPD burden. While the scale is considered suitable for use in clinical practice and research, we suggest rewording the response options to ensure uniform understanding by respondents.</p><p><p>The used data were derived from a previously conducted trial (NTR3788).</p>","PeriodicalId":10704,"journal":{"name":"COPD: Journal of Chronic Obstructive Pulmonary Disease","volume":"22 1","pages":"2557232"},"PeriodicalIF":2.1,"publicationDate":"2025-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145069192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Letter Reply to: Reassessing Gabapentinoids in Chronic Obstructive Pulmonary Disease: Emerging Respiratory Safety Concerns. 回复:重新评估加巴喷丁类药物治疗慢性阻塞性肺疾病:新出现的呼吸安全问题。
IF 2.1 4区 医学
COPD: Journal of Chronic Obstructive Pulmonary Disease Pub Date : 2025-08-14 Epub Date: 2025-08-27 DOI: 10.1080/15412555.2025.2547722
Omotayo Olaoye, Sophie Dell'Aniello, Pierre Ernst, Samy Suissa, Christel Renoux
{"title":"Letter Reply to: Reassessing Gabapentinoids in Chronic Obstructive Pulmonary Disease: Emerging Respiratory Safety Concerns.","authors":"Omotayo Olaoye, Sophie Dell'Aniello, Pierre Ernst, Samy Suissa, Christel Renoux","doi":"10.1080/15412555.2025.2547722","DOIUrl":"https://doi.org/10.1080/15412555.2025.2547722","url":null,"abstract":"","PeriodicalId":10704,"journal":{"name":"COPD: Journal of Chronic Obstructive Pulmonary Disease","volume":"22 1","pages":"2547722"},"PeriodicalIF":2.1,"publicationDate":"2025-08-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144945667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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