Compounds最新文献_第9页

Polymeric Substrates Modification with Biobased Functional Compounds 生物基功能化合物修饰聚合物底物

Compounds Pub Date : 2022-08-15 DOI: 10.3390/compounds2030016

M. Coltelli, S. Coiai

引用次数: 0

Chemical Reactivity in Microheterogeneous Media 微非均质介质中的化学反应性

Compounds Pub Date : 2022-08-02 DOI: 10.3390/compounds2030015

J. Mejuto, Antonio Cid-Samamed

引用次数: 0

Structured Supports and Catalysts: Design, Preparation, and Applications 结构支撑和催化剂:设计，制备和应用

Compounds Pub Date : 2022-07-15 DOI: 10.3390/compounds2030014

M. Martino

引用次数: 0

Quality Assessment of Medicinal Plants via Chemometric Exploration of Quantitative NMR Data: A Review 基于核磁共振定量数据化学计量学的药用植物质量评价综述

Compounds Pub Date : 2022-06-13 DOI: 10.3390/compounds2020012

A. Rebiai, B. B. Seghir, H. Hemmami, S. Zeghoud, I. B. Amor, I. Kouadri, M. Messaoudi, Ardalan Pasdaran, G. Caruso, Somesh Sharma, M. Atanassova, P. Pohl

引用次数: 2

DNA and BSA Interaction Studies and Antileukemic Evaluation of Polyaromatic Thiosemicarbazones and Their Copper Complexes 多芳硫代氨基脲及其铜配合物DNA与牛血清白蛋白相互作用研究及抗白血病评价

Compounds Pub Date : 2022-05-23 DOI: 10.3390/compounds2020011

G. Pelosi, S. Pinelli, F. Bisceglie

{"title":"DNA and BSA Interaction Studies and Antileukemic Evaluation of Polyaromatic Thiosemicarbazones and Their Copper Complexes","authors":"G. Pelosi, S. Pinelli, F. Bisceglie","doi":"10.3390/compounds2020011","DOIUrl":"https://doi.org/10.3390/compounds2020011","url":null,"abstract":"Some ten million cancer deaths occurred in 2020, highlighting the fact that the search for new anticancer drugs remains extremely topical. In the search for new coordination compounds with relevant biological properties, the choice of a metal ion is important for the design of the complex. In this regard, copper plays a peculiar role, thanks to its distinct properties. Thiosemicarbazones are, analogously, a unique class of ligands because they are easily modifiable, and therefore, extremely versatile in terms of modulating molecular properties. In this work, we synthesized and characterized, by means of X-ray diffraction, four new naphthaldehyde and anthraldehyde thiosemicarbazone derivatives and their copper complexes to be used in interaction studies with biological systems. The objective was to evaluate the antileukemic activity of these compounds. Reactions of these ligands with Cu(II) salts produced unexpected oxidation products and the isolation of Cu(I) metal complexes. One ligand and its related Cu(I) complex, which is stable in physiological conditions, were subjected to in vitro biological tests (UV-Vis and CD titration). An important interaction with DNA and an affinity toward BSA were observed in FT-IR experiments. Preliminary in vitro biological tests against a histiocytic lymphoma cell line revealed an interestingly low IC50 value, i.e., 5.46 µM, for the Cu(I) complex.","PeriodicalId":10621,"journal":{"name":"Compounds","volume":"32 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84742609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Volatile Organic Compounds in Dactylorhiza Species Dactylorhiza属植物的挥发性有机化合物

Compounds Pub Date : 2022-04-12 DOI: 10.3390/compounds2020009

Marisabel Mecca, R. Racioppi, V. Romano, L. Viggiani, R. Lorenz, M. D’Auria

引用次数: 5

A Photoswitchable Chalcone-Carbohydrate Conjugate Obtained by CuAAC Click Reaction 一种可光切换的查尔酮-碳水化合物缀合物

Compounds Pub Date : 2022-03-29 DOI: 10.3390/compounds2020008

Micael Paulino, M. M. Pereira, N. Basílio

引用次数: 2

The Nitrogen Bond, or the Nitrogen-Centered Pnictogen Bond: The Covalently Bound Nitrogen Atom in Molecular Entities and Crystals as a Pnictogen Bond Donor 氮键，或以氮为中心的pnicogen键:分子实体和晶体中作为pnicogen键供体的共价结合的氮原子

Compounds Pub Date : 2022-03-15 DOI: 10.3390/compounds2010007

P. Varadwaj, Arpita Varadwaj, H. Marques, K. Yamashita

{"title":"The Nitrogen Bond, or the Nitrogen-Centered Pnictogen Bond: The Covalently Bound Nitrogen Atom in Molecular Entities and Crystals as a Pnictogen Bond Donor","authors":"P. Varadwaj, Arpita Varadwaj, H. Marques, K. Yamashita","doi":"10.3390/compounds2010007","DOIUrl":"https://doi.org/10.3390/compounds2010007","url":null,"abstract":"The nitrogen bond in chemical systems occurs when there is evidence of a net attractive interaction between the electrophilic region associated with a covalently or coordinately bound nitrogen atom in a molecular entity and a nucleophile in another, or the same molecular entity. It is the first member of the family of pnictogen bonds formed by the first atom of the pnictogen family, Group 15, of the periodic table, and is an inter- or intra-molecular non-covalent interaction. In this featured review, we present several illustrative crystal structures deposited in the Cambridge Structure Database (CSD) and the Inorganic Crystal Structure Databases (ICSD) to demonstrate that imide nitrogen is not the only instance where nitrogen can act as an electrophilic agent. Analysis of a set of carefully chosen illustrative crystal systems shows that a covalently bound nitrogen atom in a variety of molecular entities features a σ-hole or even a π-hole, and these have the ability to sustain attractive engagements with negative sites to form inter- and/or intramolecular interactions that drive, or assist, the formation of a crystalline phase.","PeriodicalId":10621,"journal":{"name":"Compounds","volume":"137 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89073454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 14

Defect-Induced Luminescence Quenching of 4H-SiC Single Crystal Grown by PVT Method through a Control of Incorporated Impurity Concentration 通过控制杂质浓度，PVT法生长4H-SiC单晶的缺陷致发光猝灭

Compounds Pub Date : 2022-03-02 DOI: 10.3390/compounds2010006

Seul-Ki Kim, E. Y. Jung, Myung-Hyun Lee

{"title":"Defect-Induced Luminescence Quenching of 4H-SiC Single Crystal Grown by PVT Method through a Control of Incorporated Impurity Concentration","authors":"Seul-Ki Kim, E. Y. Jung, Myung-Hyun Lee","doi":"10.3390/compounds2010006","DOIUrl":"https://doi.org/10.3390/compounds2010006","url":null,"abstract":"The structural defect effect of impurities on silicon carbide (SiC) was studied to determine the luminescence properties with temperature-dependent photoluminescence (PL) measurements. Single 4H-SiC crystals were fabricated using three different 3C-SiC starting materials and the physical vapor transport method at a high temperature and 100 Pa in an argon atmosphere. The correlation between the impurity levels and the optical and fluorescent properties was confirmed using Raman spectroscopy, X-ray diffraction, inductively coupled plasma atomic emission spectroscopy (ICP-OES), UV-Vis-NIR spectrophotometry, and PL measurements. The PL intensity was observed in all three single 4H-SiC crystals, with the highest intensities at low temperatures. Two prominent PL emission peaks at 420 and 580 nm were observed at temperatures below 50 K. These emission peaks originated from the impurity concentration due to the incorporation of N, Al, and B in the single 4H-SiC crystals and were supported by ICP-OES. The emission peaks at 420 and 580 nm occurred due to donor–acceptor-pair recombination through the incorporated concentrations of nitrogen, boron, and aluminum in the single 4H-SiC crystals. The results of the present work provide evidence based on the low-temperature PL that the mechanism of PL emission in single 4H-SiC crystals is mainly related to the transitions due to defect concentration.","PeriodicalId":10621,"journal":{"name":"Compounds","volume":"28 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90473108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Effects of Electrolytes on the Dediazoniation of Aryldiazonium Ions in Acidic MeOH/H2O Mixtures 电解质对酸性MeOH/H2O混合物中芳基重氮离子脱氮的影响

Compounds Pub Date : 2022-02-15 DOI: 10.3390/compounds2010005

S. Losada-Barreiro, C. Bravo-Díaz

{"title":"Effects of Electrolytes on the Dediazoniation of Aryldiazonium Ions in Acidic MeOH/H2O Mixtures","authors":"S. Losada-Barreiro, C. Bravo-Díaz","doi":"10.3390/compounds2010005","DOIUrl":"https://doi.org/10.3390/compounds2010005","url":null,"abstract":"Aryldiazonium, ArN2+, ions decompose spontaneously through the formation of highly reactive aryl cations that undergo preferential solvation by water, showing a low selectivity towards the nucleophiles present in their solvation shell. In this work, we investigate the effects of electrolytes (NaCl, LiCl, and LiClO4) on the dediazoniation of 2-, 3-, and 4-methylbenzenediazonium ions in acidic MeOH/H2O mixtures. In the absence of electrolytes, the rates of dediazoniation, kobs, increase modestly upon increasing the MeOH content of the reaction mixture. At any solvent composition, the rate of ArN2+ loss is the same as that for product formation. The main dediazoniation products are cresols (ArOH) and methyl phenyl ethers (ArOMe). Only small amounts (less than 5%) of the reduction product toluene (ArH), which are detected at high percentages of MeOH. Quantitative yields of are obtained at any solvent composition. The addition of LiCl or NaCl ([MCl] = 0–1.5 M) to the reaction mixtures has a negligible effect on kobs but leads to the formation, in low yields (<10%), of the ArCl derivative. The addition of LiClO4 (0–1.5 M) to 20% MeOH/H2O mixtures has a negligible effect on both kobs and on the product distribution. However, at 99.5% MeOH, the addition of the same amounts of LiClO4 leads to a modest decrease in kobs but to a significant decrease in the yields of ArOMe. Results are interpreted in terms of the preferential solvation of perchlorate ions by the aryl cations, removing MeOH molecules from the solvation shell.","PeriodicalId":10621,"journal":{"name":"Compounds","volume":"31 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76921881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1