Contemporary topics in immunobiology最新文献

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Nonoxidative antimicrobial reactions of leukocytes. 白细胞的非氧化抗菌反应。
Contemporary topics in immunobiology Pub Date : 1984-01-01 DOI: 10.1007/978-1-4757-4862-8_10
J K Spitznagel
{"title":"Nonoxidative antimicrobial reactions of leukocytes.","authors":"J K Spitznagel","doi":"10.1007/978-1-4757-4862-8_10","DOIUrl":"https://doi.org/10.1007/978-1-4757-4862-8_10","url":null,"abstract":"<p><p>Increasingly abundant evidence supports the hypothesis that PMNs and perhaps alveolar macrophages have antimicrobial mechanisms independent of the presences of molecular oxygen for effective action against an array of bacteria and against some fungi. Eosinophils have mechanisms toxic for schistosomula and Trichinella larvae. In all instances the antimicrobial substances isolated have been cationic proteins and, in PMNs, associated with the azurophil cytoplasmic granules of the PMNs. Several of these substances have thus far demonstrated no enzymic function. Two of these substances are serine proteases but in one, chymotrypsin-like protein, the antimicrobial action depends on the cationic properties of the protein and is independent of the proteolytic action of the substance. In most instances, these proteins are cationic due to relatively large proportions of arginine. In two instances, a large proportion of lysine is present. All have high proportions (about 50%) of hydrophobic amino acid. Such proteins occur in the PMNs of man, rabbit, guinea pig, rat, cow, and chicken. The present view is that they are most active against gram-negative bacteria. At least two of them-37-kd and 57-kd proteins (Shafer and Spitznagel, 1983)-act on S. typhimurium in a manner analogous to that of polymyxin B through binding to lipid A. Currently available results shows that anaerobic PMNs have substantial antimicrobial capacity. Whether this capacity is due to the O2-independent mechanisms discussed in this chapter remains to be established with greater certainty.</p>","PeriodicalId":10609,"journal":{"name":"Contemporary topics in immunobiology","volume":"14 ","pages":"283-343"},"PeriodicalIF":0.0,"publicationDate":"1984-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/978-1-4757-4862-8_10","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17441009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 79
Molecular interactions and recognition specificity of surface receptors. 表面受体的分子相互作用和识别特异性。
Contemporary topics in immunobiology Pub Date : 1980-01-01 DOI: 10.1007/978-1-4615-9131-3_10
J J Marchalonis
{"title":"Molecular interactions and recognition specificity of surface receptors.","authors":"J J Marchalonis","doi":"10.1007/978-1-4615-9131-3_10","DOIUrl":"https://doi.org/10.1007/978-1-4615-9131-3_10","url":null,"abstract":"","PeriodicalId":10609,"journal":{"name":"Contemporary topics in immunobiology","volume":"9 ","pages":"255-88"},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18035079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
On network theory and H-2 restriction. 论网络理论与H-2约束。
Contemporary topics in immunobiology Pub Date : 1980-01-01 DOI: 10.1007/978-1-4684-3701-0_6
G W Hoffmann
{"title":"On network theory and H-2 restriction.","authors":"G W Hoffmann","doi":"10.1007/978-1-4684-3701-0_6","DOIUrl":"https://doi.org/10.1007/978-1-4684-3701-0_6","url":null,"abstract":"","PeriodicalId":10609,"journal":{"name":"Contemporary topics in immunobiology","volume":"11 ","pages":"185-226"},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17227063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 49
Correlations between tumor antigenicity, malignant potential, and local host immune response. 肿瘤抗原性、恶性潜能和局部宿主免疫反应的相关性。
Contemporary topics in immunobiology Pub Date : 1980-01-01 DOI: 10.1007/978-1-4684-3677-8_10
H L Ioachim
{"title":"Correlations between tumor antigenicity, malignant potential, and local host immune response.","authors":"H L Ioachim","doi":"10.1007/978-1-4684-3677-8_10","DOIUrl":"https://doi.org/10.1007/978-1-4684-3677-8_10","url":null,"abstract":"","PeriodicalId":10609,"journal":{"name":"Contemporary topics in immunobiology","volume":"10 ","pages":"213-38"},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18016979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 20
Host cell analysis of a rapidly metastasizing mouse tumor and derived low-metastatic variant lines. 快速转移小鼠肿瘤及其衍生的低转移变异系的宿主细胞分析。
Contemporary topics in immunobiology Pub Date : 1980-01-01 DOI: 10.1007/978-1-4684-3677-8_11
R S Kerbel, R R Twiddy, P Frost
{"title":"Host cell analysis of a rapidly metastasizing mouse tumor and derived low-metastatic variant lines.","authors":"R S Kerbel,&nbsp;R R Twiddy,&nbsp;P Frost","doi":"10.1007/978-1-4684-3677-8_11","DOIUrl":"https://doi.org/10.1007/978-1-4684-3677-8_11","url":null,"abstract":"","PeriodicalId":10609,"journal":{"name":"Contemporary topics in immunobiology","volume":"10 ","pages":"239-53"},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18016980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
The multicellular tumor spheroid: a quantitative model for studies of in situ immunity. 多细胞球形肿瘤:原位免疫研究的定量模型。
Contemporary topics in immunobiology Pub Date : 1980-01-01 DOI: 10.1007/978-1-4684-3677-8_15
H R MacDonald, B Sordat
{"title":"The multicellular tumor spheroid: a quantitative model for studies of in situ immunity.","authors":"H R MacDonald,&nbsp;B Sordat","doi":"10.1007/978-1-4684-3677-8_15","DOIUrl":"https://doi.org/10.1007/978-1-4684-3677-8_15","url":null,"abstract":"","PeriodicalId":10609,"journal":{"name":"Contemporary topics in immunobiology","volume":"10 ","pages":"317-42"},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/978-1-4684-3677-8_15","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18419337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 11
Salamanders and the evolution of the major histocompatibility complex. 蝾螈和主要组织相容性复合体的进化。
Contemporary topics in immunobiology Pub Date : 1980-01-01 DOI: 10.1007/978-1-4615-9131-3_5
N Cohen
{"title":"Salamanders and the evolution of the major histocompatibility complex.","authors":"N Cohen","doi":"10.1007/978-1-4615-9131-3_5","DOIUrl":"https://doi.org/10.1007/978-1-4615-9131-3_5","url":null,"abstract":"","PeriodicalId":10609,"journal":{"name":"Contemporary topics in immunobiology","volume":"9 ","pages":"109-39"},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17503337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 13
Immunologic reactivity of lymphoid cells in tumors. 淋巴样细胞在肿瘤中的免疫反应性。
Contemporary topics in immunobiology Pub Date : 1980-01-01 DOI: 10.1007/978-1-4684-3677-8_3
R B Herberman, H T Holden, L Varesio, T Taniyama, P Puccetti, H Kirchner, J Gerson, S White, Y Keisari, J S Haskill
{"title":"Immunologic reactivity of lymphoid cells in tumors.","authors":"R B Herberman,&nbsp;H T Holden,&nbsp;L Varesio,&nbsp;T Taniyama,&nbsp;P Puccetti,&nbsp;H Kirchner,&nbsp;J Gerson,&nbsp;S White,&nbsp;Y Keisari,&nbsp;J S Haskill","doi":"10.1007/978-1-4684-3677-8_3","DOIUrl":"https://doi.org/10.1007/978-1-4684-3677-8_3","url":null,"abstract":"","PeriodicalId":10609,"journal":{"name":"Contemporary topics in immunobiology","volume":"10 ","pages":"61-78"},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18016982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 44
Separation and characteristics of tumor-infiltrating lymphocytes in man. 人肿瘤浸润淋巴细胞的分离与特征。
Contemporary topics in immunobiology Pub Date : 1980-01-01 DOI: 10.1007/978-1-4684-3677-8_4
E Klein, F Vánky, U Galili, B M Vose, M Fopp
{"title":"Separation and characteristics of tumor-infiltrating lymphocytes in man.","authors":"E Klein,&nbsp;F Vánky,&nbsp;U Galili,&nbsp;B M Vose,&nbsp;M Fopp","doi":"10.1007/978-1-4684-3677-8_4","DOIUrl":"https://doi.org/10.1007/978-1-4684-3677-8_4","url":null,"abstract":"","PeriodicalId":10609,"journal":{"name":"Contemporary topics in immunobiology","volume":"10 ","pages":"79-107"},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18016983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 55
Discrimination of self and non-self in invertebrates. 无脊椎动物对自我和非自我的区分。
Contemporary topics in immunobiology Pub Date : 1980-01-01 DOI: 10.1007/978-1-4615-9131-3_2
M J Chorney, T C Cheng
{"title":"Discrimination of self and non-self in invertebrates.","authors":"M J Chorney,&nbsp;T C Cheng","doi":"10.1007/978-1-4615-9131-3_2","DOIUrl":"https://doi.org/10.1007/978-1-4615-9131-3_2","url":null,"abstract":"","PeriodicalId":10609,"journal":{"name":"Contemporary topics in immunobiology","volume":"9 ","pages":"37-54"},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/978-1-4615-9131-3_2","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18035080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 29
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