{"title":"Systemic and local immunity in allograft and cancer rejection.","authors":"J S Haskill, P Häyry, L A Radov","doi":"10.1007/978-1-4684-0922-2_5","DOIUrl":"https://doi.org/10.1007/978-1-4684-0922-2_5","url":null,"abstract":"","PeriodicalId":10609,"journal":{"name":"Contemporary topics in immunobiology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1978-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11567639","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"In vitro induction and expression of T-cell immunity to tumor-associated antigens.","authors":"R C Burton, S E Chism, N L Warner","doi":"10.1007/978-1-4684-0922-2_4","DOIUrl":"https://doi.org/10.1007/978-1-4684-0922-2_4","url":null,"abstract":"","PeriodicalId":10609,"journal":{"name":"Contemporary topics in immunobiology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1978-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11567644","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Allotypes of IgM and IgD receptors in the mouse: a probe for lymphocyte differentiation.","authors":"J W Goding","doi":"10.1007/978-1-4684-0922-2_7","DOIUrl":"https://doi.org/10.1007/978-1-4684-0922-2_7","url":null,"abstract":"<p><p>Antibodies to IgD and IgM are present in many mouse alloantisera made against lymphocytes. Antibodies to IgM are also present in a small minority of conventional antiallotype sera made against pertussis/anti-pertussis complexes. These antibodies reflect different allelic forms of IgD and IgM in different mouse strains, and allowed the mapping of the delta- and mu-chain genes (Ig-5 and Ig-6, respectively) to the heavy-chain complex. The variable portions of IgM and IgD receptors on individual cells bearing both chains are similar or identical. Both receptors show allelic exclusion and come from the same chromosome on individual cells (haplotype exclusion). It is suggested that very early in B lymphocyte differentiation there is a commitment to a given chromosome, and translocation of one copy of a given variable region gene to each heavy-chain gene. Subsequent switches of immunoglobulin class then involve differential gene activation. Immature B cells possess IgM receptors only and mature into cells bearing both IgM and IgD receptors. After activation with antigen, IgD is probably lost. These findings are discussed within the framework of the clonal abortion theory of B-lymphocyte tolerance.</p>","PeriodicalId":10609,"journal":{"name":"Contemporary topics in immunobiology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1978-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11567641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Major transplantation antigens, viruses, and specificity of surveillance T cells.","authors":"R M Zinkernagel, P C Doherty","doi":"10.1007/978-1-4684-3054-7_5","DOIUrl":"https://doi.org/10.1007/978-1-4684-3054-7_5","url":null,"abstract":"","PeriodicalId":10609,"journal":{"name":"Contemporary topics in immunobiology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1977-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11290487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Significance of the major histocompatibility complex as assessed by T-cell-mediated lympholysis involving syngeneic stimulating cells.","authors":"G M Shearer, A M Schmitt-Verhulst, T G Rehn","doi":"10.1007/978-1-4684-3054-7_6","DOIUrl":"https://doi.org/10.1007/978-1-4684-3054-7_6","url":null,"abstract":"","PeriodicalId":10609,"journal":{"name":"Contemporary topics in immunobiology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1977-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11290488","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Mechanism of specific tumor-cell lysis by alloimmune T lymphocytes: resolution and characterization of discrete steps in the cellular interaction.","authors":"E Martz","doi":"10.1007/978-1-4684-3054-7_9","DOIUrl":"https://doi.org/10.1007/978-1-4684-3054-7_9","url":null,"abstract":"","PeriodicalId":10609,"journal":{"name":"Contemporary topics in immunobiology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1977-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11613749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Mechanism of T-cell-mediated cytolysis: the lethal hit stage.","authors":"P Golstein, E T Smith","doi":"10.1007/978-1-4684-3054-7_8","DOIUrl":"https://doi.org/10.1007/978-1-4684-3054-7_8","url":null,"abstract":"","PeriodicalId":10609,"journal":{"name":"Contemporary topics in immunobiology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1977-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11539975","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Functional analysis of distinct human T-cell subsets bearing unique differentiation antigens.","authors":"L Chess, S F Schlossman","doi":"10.1007/978-1-4684-3054-7_10","DOIUrl":"https://doi.org/10.1007/978-1-4684-3054-7_10","url":null,"abstract":"","PeriodicalId":10609,"journal":{"name":"Contemporary topics in immunobiology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1977-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11539976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Immunogenicity and MuMTV-like antigenicity of human breast cancer tissues.","authors":"M M Black","doi":"10.1007/978-1-4684-3051-6_9","DOIUrl":"https://doi.org/10.1007/978-1-4684-3051-6_9","url":null,"abstract":"","PeriodicalId":10609,"journal":{"name":"Contemporary topics in immunobiology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1977-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11410766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Immunity to leukemia, lymphoma, and fibrosarcoma in cats: a case for immunosurveillance.","authors":"M Essex","doi":"10.1007/978-1-4684-3051-6_2","DOIUrl":"https://doi.org/10.1007/978-1-4684-3051-6_2","url":null,"abstract":"","PeriodicalId":10609,"journal":{"name":"Contemporary topics in immunobiology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1977-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11410768","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}