Communications Materials最新文献_第10页

Multiple intermediates in the detergent-induced fusion of lipid vesicles 去污剂诱导脂质囊泡融合的多个中间体

IF 7.5

Communications Materials Pub Date : 2024-09-19 DOI: 10.1038/s43246-024-00628-8

Lara G. Dresser, Casper Kunstmann-Olsen, Donato Conteduca, Christopher M. Hofmair, Nathan Smith, Laura Clark, Steven Johnson, J. Carlos Penedo, Mark C. Leake, Steven D. Quinn

{"title":"Multiple intermediates in the detergent-induced fusion of lipid vesicles","authors":"Lara G. Dresser, Casper Kunstmann-Olsen, Donato Conteduca, Christopher M. Hofmair, Nathan Smith, Laura Clark, Steven Johnson, J. Carlos Penedo, Mark C. Leake, Steven D. Quinn","doi":"10.1038/s43246-024-00628-8","DOIUrl":"10.1038/s43246-024-00628-8","url":null,"abstract":"Detergent-induced vesicle interactions, critical for applications including virus inactivation, varies according to the detergent type and membrane composition, but the underlying mechanistic details remain underexplored. Here, we use a lipid mixing assay based on Förster resonance energy transfer (FRET), and single-vesicle characterization approaches to identify that sub-micron-sized vesicles are induced to fuse by the non-ionic detergent Triton-X-100. We demonstrate that the process is a multi-step mechanism, characterized by discrete values of FRET efficiency between membrane-embedded fluorophores, and involves permeabilization, vesicle docking, hemi-fusion and full lipid mixing at sub-solubilizing detergent concentrations. We also dissect the kinetics of vesicle fusion to surface-tethered vesicles using a label-free quartz-crystal microbalance with dissipation monitoring approach, opening a platform for biotechnology applications. The presented strategies provide mechanistic insight into the dynamics of vesicle fusion and have implications for applications including drug delivery and sensor development where transport and manipulation of encapsulated cargo is essential. Detergent-induced membrane interactions are important for biotechnology applications but their mechanism is still not well understood. Here, sub-micron-sized vesicles are shown to fuse by a non-ionic detergent, involving permeabilization, vesicle docking, hemi-fusion, and full lipid mixing steps.","PeriodicalId":10589,"journal":{"name":"Communications Materials","volume":" ","pages":"1-12"},"PeriodicalIF":7.5,"publicationDate":"2024-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.com/articles/s43246-024-00628-8.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142255331","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Selective reductive conversion of CO2 to CH2-bridged compounds by using a Fe-functionalized graphene oxide-based catalyst 使用铁功能化氧化石墨烯基催化剂将二氧化碳选择性还原转化为 CH2-桥接化合物

IF 7.5

Communications Materials Pub Date : 2024-09-19 DOI: 10.1038/s43246-024-00639-5

Swarbhanu Ghosh, Parisa A. Ariya

{"title":"Selective reductive conversion of CO2 to CH2-bridged compounds by using a Fe-functionalized graphene oxide-based catalyst","authors":"Swarbhanu Ghosh, Parisa A. Ariya","doi":"10.1038/s43246-024-00639-5","DOIUrl":"10.1038/s43246-024-00639-5","url":null,"abstract":"Anthropogenic climate change drastically affects our planet, with CO2 being the most critical gaseous driver. Despite the existing carbon dioxide capture and transformation, there is much need for innovative carbon dioxide hydrogenation catalysts with excellent selectivity. Here, we present a fast, effective, and sustainable route for coupling diverse alcohols, amines and amides with CO2 via heterogenization of a natural metal-based homogeneous catalyst through decorating on functionalized graphene oxide (GO). Combined synthetic, experimental, and theoretical studies unravel mechanistic routes to convergent 4‑electron reduction of CO2 under mild conditions. We successfully replace the toxic and expensive ruthenium species with inexpensive, ubiquitously available and recyclable iron. This iron-based functionalized graphene oxide (denoted as Fe@GO-EDA, where EDA represents ethylenediamine) functions as an efficient catalyst for the selective conversion of CO2 into a formaldehyde oxidation level, thus opening the door for interesting molecular structures using CO2 as a C1 source. Overall, this work describes an intriguing heterogeneous platform for the selective synthesis of valuable methylene-bridged compounds via 4‑electron reduction of CO2. Carbon dioxide in the atmosphere can be captured and transformed to useful chemicals with hydrogenation catalysts. Here, iron-functionalized graphene oxide-based catalyst functions as an effective catalyst for the selective conversion of carbon dioxide into a formaldehyde oxidation level.","PeriodicalId":10589,"journal":{"name":"Communications Materials","volume":" ","pages":"1-17"},"PeriodicalIF":7.5,"publicationDate":"2024-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.com/articles/s43246-024-00639-5.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142255285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Materials and methods for cost-effective fabrication of perovskite photovoltaic devices 经济高效地制造过氧化物光伏器件的材料和方法

IF 7.5

Communications Materials Pub Date : 2024-09-18 DOI: 10.1038/s43246-024-00636-8

Chunyang Zhang, Nam-Gyu Park

引用次数: 0

Intrinsically microporous polyimide-based metal-free catalysts for round-the-clock photodegradation of organic pollutants 用于全天候光降解有机污染物的本征微孔聚酰亚胺基无金属催化剂

IF 7.5

Communications Materials Pub Date : 2024-09-18 DOI: 10.1038/s43246-024-00629-7

Zainah A. AlDhawi, Ridha Hamdi, Mahmoud A. Abdulhamid

{"title":"Intrinsically microporous polyimide-based metal-free catalysts for round-the-clock photodegradation of organic pollutants","authors":"Zainah A. AlDhawi, Ridha Hamdi, Mahmoud A. Abdulhamid","doi":"10.1038/s43246-024-00629-7","DOIUrl":"10.1038/s43246-024-00629-7","url":null,"abstract":"Photocatalytic degradation of organic pollutants is an essential technology for various environmental applications. However, the effectiveness of most photocatalysts is restricted to light. Herein, we report metal-free catalysts derived from intrinsically microporous polyimide for persistence in photocatalytic degradation of dyes. We systematically investigate the effect of porosity and functionality on photocatalytic efficiency. Both the pristine 4,4′-(hexafluoroisopropylidene)diphthalic anhydride-3,3′-dimethylnaphthidine and its thermally annealed counterpart at 530 °C exhibit high charge storage capabilities, enabling continuous photodegradation in the absence of light. The pre-irradiated catalyst exhibits an approximately 99% degradation of the dye, with a ~40% improvement relative to the non-pre-irradiated sample. We studied the influence of the chemical structure and porosity on the photocatalytic degradation efficiency in darkness by varying the polyimide chemical structure using different diamines. This research underscores the potential of polymers with intrinsic microporosity for application in the continuous degradation of dyes, contributing to the pursuit of cleaner water. Photodegradation of pollutants is important to produce clean water but their activities are restricted during nighttime. Here, metal-free catalysts derived from intrinsically microporous polyimide show efficient photocatalytic degradation activities of dyes under light and darkness.","PeriodicalId":10589,"journal":{"name":"Communications Materials","volume":" ","pages":"1-12"},"PeriodicalIF":7.5,"publicationDate":"2024-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.com/articles/s43246-024-00629-7.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142255335","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Exploring rare-earth Kitaev magnets by massive-scale computational analysis 通过大规模计算分析探索稀土基塔耶夫磁体

IF 7.5

Communications Materials Pub Date : 2024-09-18 DOI: 10.1038/s43246-024-00634-w

Seong-Hoon Jang, Yukitoshi Motome

{"title":"Exploring rare-earth Kitaev magnets by massive-scale computational analysis","authors":"Seong-Hoon Jang, Yukitoshi Motome","doi":"10.1038/s43246-024-00634-w","DOIUrl":"10.1038/s43246-024-00634-w","url":null,"abstract":"The Kitaev honeycomb model plays a pivotal role in the quest for quantum spin liquids, in which fractional quasiparticles would provide applications in decoherence-free topological quantum computing. The key ingredient is the bond-dependent Ising-type interactions, dubbed the Kitaev interactions, which require strong entanglement between spin and orbital degrees of freedom. Here we investigate the identification and design of rare-earth materials displaying robust Kitaev interactions. We scrutinize all possible 4f electron configurations, which require up to 6+ million intermediate states in the perturbation processes, by developing a parallel computational program designed for massive-scale calculations. Our analysis reveals a predominant interplay between the isotropic Heisenberg J and anisotropic Kitaev K interactions across all realizations of the Kramers doublets. Remarkably, instances featuring 4f3 and 4f11 configurations showcase the prevalence of K over J, presenting unexpected prospects for exploring the Kitaev quantum spin liquids in compounds, including Nd3+ and Er3+, respectively. Kitaev magnets are interesting as they can host quantum spin liquid phases and fractional quasiparticles for decoherence-free topological quantum computing. Here, a parallel computational program explores all possible 4f electron configurations of rare-earth Kitaev materials, identifying those configurations, such as 4f3 and 4f11 in Nd3+ and Er3+ compounds, where anisotropic Kitaev interactions prevail over isotropic Heisenberg exchange.","PeriodicalId":10589,"journal":{"name":"Communications Materials","volume":" ","pages":"1-8"},"PeriodicalIF":7.5,"publicationDate":"2024-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.com/articles/s43246-024-00634-w.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142255248","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Scaleable production of highly loaded protein nanoparticles for immune modulation 用于免疫调节的高负载蛋白质纳米颗粒的规模化生产

IF 7.5

Communications Materials Pub Date : 2024-09-17 DOI: 10.1038/s43246-024-00626-w

Michael J. Caplan, Richard Baldwin, Xiangyun Yin, Alexander Grishin, Stephanie Eisenbarth, Hugh A. Sampson, Kim Bottomly, Robert K. Prud’homme

{"title":"Scaleable production of highly loaded protein nanoparticles for immune modulation","authors":"Michael J. Caplan, Richard Baldwin, Xiangyun Yin, Alexander Grishin, Stephanie Eisenbarth, Hugh A. Sampson, Kim Bottomly, Robert K. Prud’homme","doi":"10.1038/s43246-024-00626-w","DOIUrl":"10.1038/s43246-024-00626-w","url":null,"abstract":"Immune modulation and  desensitization is a growing field of research and clinical investigation that requires precise delivery of antigens to immune system cells. Nanoparticles (NPs) have emerged as excellent candidates for antigen delivery, particularly in immune desensitization applications. NP-encapsulated protein antigens enable the delivery of protein and co-encapsulated adjuvant to antigen-presenting cells without systemic exposure and allergic response. Here, we show a method for producing poly(lactide-co-glycolide) (PLG) NPs in an efficient, high-yield, and large-scale inhomogeneous precipitation process. The process enables the production of compositionally complex PLG NPs containing protein while also incorporating DNA and E. coli phospholipids as integral adjuvants in the NP vehicle. Orally delivered PLG NPs activate the murine immune system, and encapsulated peanut allergen protein elicits approximately 10-fold lower levels of basophil activation than does unencapsulated protein in basophils isolated from peanut-allergic patients. This efficacy and safety evidence makes these PLG NPs excellent candidates for clinical applications. Protein-loaded nanoparticles are important for immunomodulatory applications. Here, an efficient method for producing protein-containing nanoparticles at large scale is developed which overcomes prior limitations on the use of poly(lactide-co-glycolide) nanoparticles.","PeriodicalId":10589,"journal":{"name":"Communications Materials","volume":" ","pages":"1-11"},"PeriodicalIF":7.5,"publicationDate":"2024-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.com/articles/s43246-024-00626-w.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142255249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Defect-engineered monolayer MoS2 with enhanced memristive and synaptic functionality for neuromorphic computing 用于神经形态计算的具有增强记忆和突触功能的缺陷工程单层 MoS2

IF 7.5

Communications Materials Pub Date : 2024-09-16 DOI: 10.1038/s43246-024-00632-y

Manisha Rajput, Sameer Kumar Mallik, Sagnik Chatterjee, Ashutosh Shukla, Sooyeon Hwang, Satyaprakash Sahoo, G. V. Pavan Kumar, Atikur Rahman

{"title":"Defect-engineered monolayer MoS2 with enhanced memristive and synaptic functionality for neuromorphic computing","authors":"Manisha Rajput, Sameer Kumar Mallik, Sagnik Chatterjee, Ashutosh Shukla, Sooyeon Hwang, Satyaprakash Sahoo, G. V. Pavan Kumar, Atikur Rahman","doi":"10.1038/s43246-024-00632-y","DOIUrl":"10.1038/s43246-024-00632-y","url":null,"abstract":"Two-dimensional transition metal dichalcogenides (TMDs)-based memristors are promising candidates for realizing artificial synapses in next-generation computing. However, practical implementation faces several challenges, such as high non-linearity and asymmetry in synaptic weight updates, limited dynamic range, and cycle-to-cycle variability. Here, utilizing optimal-power argon plasma treatment, we significantly enhance the performance matrix of memristors fabricated from monolayer MoS2. Our approach not only improves linearity and symmetry in synaptic weight updates but also increases the number of available synaptic weight updates and enhances Spike-Time Dependent Plasticity. Notably, it broadens the switching ratio by two orders, minimizes cycle-to-cycle variability, reduces non-linear factors, and achieves an energy consumption of  ~30 fJ per synaptic event. Implementation of these enhancements is demonstrated through Artificial Neural Network simulations, yielding a learning accuracy of  ~97% on the MNIST hand-written digits dataset. Our findings underscore the significance of defect engineering as a powerful tool in advancing the synaptic functionality of memristors. Memristors based on 2D materials are promising candidates for realizing artificial synapses in next-generation computing. Here, utilizing optimal-power argon plasma treatment, the authors enhance the performance of memristors fabricated from monolayer MoS2, reducing non-linearity and asymmetry in synaptic weight updates and minimizing cycle-to-cycle variability.","PeriodicalId":10589,"journal":{"name":"Communications Materials","volume":" ","pages":"1-14"},"PeriodicalIF":7.5,"publicationDate":"2024-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.com/articles/s43246-024-00632-y.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142234031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

High-temperature Brown-Zak oscillations in graphene/hBN moiré field effect transistor fabricated using molecular beam epitaxy 利用分子束外延技术制造的石墨烯/卤化硼莫伊里场效应晶体管中的高温布朗-扎克振荡

IF 7.5

Communications Materials Pub Date : 2024-09-14 DOI: 10.1038/s43246-024-00633-x

Oleg Makarovsky, Richard J. A. Hill, Tin S. Cheng, Alex Summerfield, Takeshi Taniguchi, Kenji Watanabe, Christopher J. Mellor, Amalia Patanè, Laurence Eaves, Sergei V. Novikov, Peter H. Beton

{"title":"High-temperature Brown-Zak oscillations in graphene/hBN moiré field effect transistor fabricated using molecular beam epitaxy","authors":"Oleg Makarovsky, Richard J. A. Hill, Tin S. Cheng, Alex Summerfield, Takeshi Taniguchi, Kenji Watanabe, Christopher J. Mellor, Amalia Patanè, Laurence Eaves, Sergei V. Novikov, Peter H. Beton","doi":"10.1038/s43246-024-00633-x","DOIUrl":"10.1038/s43246-024-00633-x","url":null,"abstract":"Graphene placed on hexagonal boron nitride (hBN) has received significant interest due to its excellent electrical performance and physics phenomena, such as superlattice Dirac points. Direct molecular beam epitaxy growth of graphene on hBN offers an alternative fabrication route for hBN/graphene devices. Here, we investigate the electronic transport of moiré field effect transistors (FETs) in which the conducting channel is monolayer graphene grown on hexagonal boron nitride by high temperature molecular beam epitaxy (HT-MBE). Alignment between hBN and HT-MBE graphene crystal lattices gives rise to a moiré-fringed hexagonal superlattice pattern. Its electronic band structure takes the form of a “Hofstadter butterfly”. When a strong magnetic field B is applied perpendicular to the graphene layer, the electrical conductance displays magneto-oscillations, periodic in B−1, over a wide range of gate voltages and temperatures up to 350 K. We attribute this behaviour to the quantisation of electronic charge and magnetic flux within each unit cell of the superlattice, which gives rise to so-called Brown-Zak oscillations, previously reported only in high-mobility exfoliated graphene. Thus, this HT-MBE graphene/hBN heterostructure provides a platform for observation of room temperature quantum effects and device applications. Moiré field-effect transistors based on graphene/hexagonal boron nitride heterostructures are promising for their high room-temperature carrier mobilities and magnetotransport properties. Here, high-temperature molecular beam epitaxy growth of graphene/hBN gives rise to a moiré-fringed hexagonal superlattice with Hofstadter butterfly electronic band structure and quantum magneto-oscillations above room temperature.","PeriodicalId":10589,"journal":{"name":"Communications Materials","volume":" ","pages":"1-6"},"PeriodicalIF":7.5,"publicationDate":"2024-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.com/articles/s43246-024-00633-x.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142234035","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Toward direct band gaps in typical 2D transition-metal dichalcogenides junctions via real and energy spaces tuning 通过实空间和能量空间调整实现典型二维过渡金属二钙化结的直接带隙

IF 7.5

Communications Materials Pub Date : 2024-09-13 DOI: 10.1038/s43246-024-00631-z

Mei-Yan Tian, Yu-Meng Gao, Yue-Jiao Zhang, Meng-Xue Ren, Xiao-Huan Lv, Ke-Xin Hou, Chen-Dong Jin, Hu Zhang, Ru-Qian Lian, Peng-Lai Gong, Rui-Ning Wang, Jiang-Long Wang, Xing-Qiang Shi

{"title":"Toward direct band gaps in typical 2D transition-metal dichalcogenides junctions via real and energy spaces tuning","authors":"Mei-Yan Tian, Yu-Meng Gao, Yue-Jiao Zhang, Meng-Xue Ren, Xiao-Huan Lv, Ke-Xin Hou, Chen-Dong Jin, Hu Zhang, Ru-Qian Lian, Peng-Lai Gong, Rui-Ning Wang, Jiang-Long Wang, Xing-Qiang Shi","doi":"10.1038/s43246-024-00631-z","DOIUrl":"10.1038/s43246-024-00631-z","url":null,"abstract":"Most of the van der Waals homo- and hetero-junctions of group VIB two-dimensional (2D) transition-metal dichalcogenides (TMDs; MoS2, WS2, MoSe2, and WSe2) show indirect energy band gaps which hinders some of their applications especially in optoelectronics. In the current work, we demonstrate that most of the bilayers and even few-layers consisting of group VIB TMDs can have direct gaps by efficient weakening of their interlayer interactions via real and/or energy spaces tuning, which is based on insights from quantitative analyses of interlayer electronic hybridizations. Real space tuning here means introducing large-angle rotational misalignment between layers, which has been realized in a very recent experiment; and, energy space tuning means introducing energy mismatch between layers which can be introduced efficiently by different means thanks to the small vertical dielectric constant of 2D semiconducting TMDs. The efficient tuning in both real and energy spaces proposed here paves an avenue for indirect-direct gap regulation of homo- and hetero-junctions of TMDs and other 2D semiconductors. Notably, both tuning can be permanently preserved and hence our work is of great significance for the diverse applications of 2D semiconductors. Most van der Waals homo- and hetero-junctions of 2D transition-metal dichalcogenides of group VIB have indirect bandgaps. Here, the authors demonstrate a way of inducing direct gaps in these systems by tuning interlayer interactions via rotational misalignment or energy mismatch between layers.","PeriodicalId":10589,"journal":{"name":"Communications Materials","volume":" ","pages":"1-9"},"PeriodicalIF":7.5,"publicationDate":"2024-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.com/articles/s43246-024-00631-z.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142234042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Transformation of europium metal-organic framework from 3D via 2D into exfoliating 3D for enzyme immobilization 将铕金属有机框架从三维通过二维转化为用于酶固定的剥离三维

IF 7.5

Communications Materials Pub Date : 2024-09-12 DOI: 10.1038/s43246-024-00624-y

Ani Vardanyan, Guojun Zhou, Nayoung Kim, Tetyana M. Budnyak, Vadim G. Kessler, Insung S. Choi, Zhehao Huang, Gulaim A. Seisenbaeva

{"title":"Transformation of europium metal-organic framework from 3D via 2D into exfoliating 3D for enzyme immobilization","authors":"Ani Vardanyan, Guojun Zhou, Nayoung Kim, Tetyana M. Budnyak, Vadim G. Kessler, Insung S. Choi, Zhehao Huang, Gulaim A. Seisenbaeva","doi":"10.1038/s43246-024-00624-y","DOIUrl":"10.1038/s43246-024-00624-y","url":null,"abstract":"Metal-organic frameworks (MOFs) have emerged as highly promising materials for hosting functional biomolecules. Here, a 1,2,4-benzenetricarboxylate ligand with a flat asymmetric shape is applied to infuse an unusual behavior to a 3D europium MOF (SLU-1). Solvent addition results in the 3D MOF splitting into a 2D one (SLU-2), and in the presence of excess water, gets cross-linked into a different 3D MOF (SLU-3) prone to spontaneous exfoliation. SLU-3 features a combination of highly hydrophilic and hydrophobic spots and serves as an attractive host for incorporating large active species. As a representative demonstration, horseradish peroxidase (HRP) is incorporated into the exfoliated 3D-layered structure by simple mixing, and secured by an outer silica layer in the form of core-shell structures. The resulting HRP-based biocatalyst exhibited enhanced stability and reusability, effectively degrading phenol. This work showcases the potential of reconfigurable MOFs, offering upheld applications through the controlled uptake and retention of biocatalytic agents. Metal-organic frameworks are promising materials for hosting functional biomolecules. Here, a 3D europium metal-organic framework could split into a 2D one upon solvent addition and re-cross-link to 3D with excess solvent which can host enzymes as a biocatalyst.","PeriodicalId":10589,"journal":{"name":"Communications Materials","volume":" ","pages":"1-10"},"PeriodicalIF":7.5,"publicationDate":"2024-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.nature.com/articles/s43246-024-00624-y.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142206413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0